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| 1 | Global Wheat Head Detection 2021:An Improved Dataset for Benchmarking Wheat Head Detection Methods显示文摘The Global Wheat Head Detection(GWHD)dataset was created in 2020 and has assembled 193,634 labelled wheat heads from 4700 RGB images acquired from various acquisition platforms and 7 countries/institutions.With an associated competition hosted in Kaggle,GWHD_2020 has successfully attracted attention from both the computer vision and agricultural science communities.From this first experience,a few avenues for improvements have been identified regarding data size,head diversity,and label reliability.To address these issues,the 2020 dataset has been reexamined,relabeled,and complemented by adding 1722 images from 5 additional countries,allowing for 81,553 additional wheat heads.We now release in 2021 a new version of the Global Wheat Head Detection dataset,which is bigger,more diverse,and less noisy than the GWHD_2020 version. | Etienne David Mario Serouart Daniel Smith Simon Madec Kaaviya Velumani Shouyang Liu Xu Wang Francisco Pinto Shahameh Shafiee Izzat SATahir Hisashi Tsujimoto Shuhei Nasuda Bangyou Zheng Norbert Kirchgessner Helge Aasen Andreas Hund Pouria Sadhegi-Tehran Koichi Nagasawa Goro Ishikawa Sébastien Dandrifosse Alexis Carlier Benjamin Dumont Benoit Mercatoris Byron Evers Ken Kuroki Haozhou Wang Masanori Ishii Minhajul ABadhon Curtis Pozniak David Shaner LeBauer Morten Lillemo Jesse Poland Scott Chapman Benoit de Solan Frédéric Baret Ian Stavness Wei Guo | 2021 | Plant Phenomics2021，3，1： | 2 |
| 2 | Saccharomyces cerevisiae CNCM I-3856 in irritable bowel syndrome: An individual subject meta-analysis显示文摘AIM To confirm previous conclusions on Saccharomyces cerevisiae(S. cerevisiae) CNCM I-3856 for irritable bowel syndrome(IBS) management.METHODS An individual patient data meta-analysis was performed on two randomized clinical trials studying the effect of S. cerevisiae CNCM I-3856 supplementation on gastrointestinal(GI) symptoms in IBS subjects. A total of 579 IBS subjects were included. Outcomes were the daily Likert scale scores of abdominal pain/discomfort and bloating [area under the curve(AUC) and weekly means], responder status, and bowel movements(stool frequency and consistency). Statistical analyses were conducted in Intent to Treat(ITT) population, IBS-C subjects and IBS-C subjects with an abdominal pain/discomfort score higher than or equal to 2 at baseline('IBS-C ≥ 2 subpopulation').RESULTS S. cerevisiae CNCM I-3856 significantly improved abdominal pain/discomfort and bloating during the second month of supplementation [AUC(W5-W8)]with improvement up to the minimal clinically relevant threshold of 10%: a 12.3% reduction of abdominal pain/discomfort in the ITT population compared to the Placebo group(P = 0.0134) has been observed. In the IBS-C ≥ 2 subpopulation, there were a 13.1% reduction of abdominal pain/discomfort and a 14.9% reduction of bloating compared to the Placebo group(P = 0.0194 and P = 0.0145, respectively). GI symptoms significantly decreased during supplementation but no statistical differences were reported between groups at the end of the supplementation period. Responder status was defined as a subject who experienced a decrease of 1 arbitrary unit(a.u.) or 50% of the abdominal discomfort score from baseline for at least 2 wk out of the last 4 wk of the study. A significant difference between groups was reported in the ITT population, when considering the first definition: subjects in the Active group had 1.510 higher odds to be a responder(reduction of 1 a.u. of abdominal pain/discomfort) compared with subjects in the Placebo group(P = 0.0240). At the end of supplementation period, stool consistency in the Active group of the ITT population was significantly improved and classified as 'normal' compared to Placebo(respectively 3.13 ± 1.197 a.u. vs 2.58 ± 1.020 a.u., P = 0.0003). Similar results were seen in the IBS-C ≥ 2 subpopulation(Active group: 3.14 ± 1.219 a.u. vs Placebo group: 2.59 ± 1.017 a.u., P = 0.0009).CONCLUSION This meta-analysis supports previous data linking S. cerevisiae I-3856 and improvement of GI symptoms, in IBS overall population and in the IBS-C and IBS-C ≥ 2 subpopulations. | Amélie Cayzeele-Decherf Fanny Pélerin Sébastien Leuillet Benoit Douillard Béatrice Housez Murielle Cazaubiel Gunnard K Jacobson Peter Jüsten Pierre Desreumaux | 2017 | World Journal of Gastroenterology2017，23，2： | 2 |
| 3 | Effect of low temperature in the development cycle of Lucilia sericata (Meigen) (Diptera, Calliphoridae): implications for the minimum postmortem interval estimation显示文摘Knowledge of necrophagous insects' developmental data is necessary for the forensic entomologist to estimate a reliable minimum postmortem interval (PMImin).Among the most represented necrophagous species,Lucilia sericata (Diptera,Calliphoridae) is particularly interesting.It is regularly identified in samples,with a predominance in summer,and is commonly used by analysts of our entomology department (Institut de Recherche Criminelle de la Gendarmerie Nationale) to estimate the PMImin with the accumulated degree days (ADD) method.This method requires the mathematical lower thermal threshold to be known.This value dictates the quality of the applied ADD method but cannot be considered as fixed,especially when insect development occurs at temperatures close to the biological threshold.In such conditions,it is necessary to study the influence of such temperatures on development rate,as well as the consequences of estimating the period of first oviposition on cadavers,when using the ADD method.Seven replicate rearings were conducted at six different temperatures: 30 ℃,24 ℃,18 ℃,15 ℃,12 ℃ and 10 ℃.Time of development and time of emergence were recorded.The effect of low temperature on the development cycle and the reliability of the ADD method under this entire temperature spectrum were studied using different linear regression models.Calculated durations of total insect time development and experimental rearing duration were then compared.A global linear model cannot be used on the whole temperature spectrum experienced by L.sericata without resulting in an overestimation at some temperatures.We found a combination of two linear regression models to be suitable for the estimation of the total development time,depending on the temperature experienced by L.sericata.This approach allowed us to obtain a variation lower than 2% at 12 ℃ and 10 ℃ between the calculated duration and experimental duration of development.In comparison,the results obtained with a global model show a variation higher than 3% at 12 ℃ and 10%at 10℃. | Laetitia Cervantès Laurent Dourel Emmanuel Gaudry Thierry Pasquerault Benoit Vincent | 2018 | Forensic Sciences Research2018，3，1： | 2 |
| 4 | Fingolimod potentiates the effects of sunitinib malate in a rat breast cancer model显示文摘 | Yoanne Mousseau Séverine Mollard Karine Faucher-Durand Laurence Richard Angélique Nizou Jeanne Cook-Moreau Yasser Baaj Hao Qiu Xavier Plainard Laurent Fourcade Benoit Funalot Franck G. Sturtz | 2012 | Breast Cancer Research and Treatment2012，，1： | 1 |
| 5 | Immunohistochemical analysis of CD4^+ and CD8^+T-cell subsets in high-risk human papillomavirus-associated pre-maligant and maligant leisions of the uterine cervix 显示文摘 | Monnier Benoit S Mannvf F | 2006 | Gynecol Onco12006，102，1： | 1 |
| 6 | Ghrelin controls hippocampal spine synapse density and memory performance 显示文摘 | Diano S Farr SA Benoit SC | 2006 | Nat Neurosci2006，9，3： | 1 |
| 7 | Influence of chemical modification of anthracite on the porosity of the resulting activated carbons显示文摘 | LYUBCHIK S B BENOIT R BGUIN F | 2002 | Carbon2002，，40： | 1 |
| 8 | Runoff and soil erosion during spring thaw in the northern US Corn Belt显示文摘 | Sharratt B S Lindstrom M J Benoit G R | 2000 | Journal of Soil and Water Conservation2000，55，4： | 1 |
| 9 | Insulin and leptin combine additively to reduce food intake and body weigh in mt 显示文摘 | Air E L Benoit S C Clegg O J | 2002 | Endocrinol2002，143，6： | 1 |
| 10 | Synthesis,structural characterization, experimental, and computational spectrophotometric studies of 8-quinolinyloxymethypho- sphonate compounds 显示文摘 | Man S P Benoit D M Buchaca E | 2006 | Inorg Chem2006，45，： | 1 |
| 11 | Development of a zebrafish 4-day embryo-larval bioassay to assess toxicity of chemicals显示文摘 | BENOIT F RAPHAEL M S JEANNE G | 2006 | Ecotoxicology and Environmental Safety2006，63，2： | 1 |
| 12 | Favorable outcome with bevacizumab after poor outcome with steroids in a patient with temporal lobe and brainstem radiation necrosis显示文摘 | Benoit A Ducray F Cartalat-Carel S | 2011 | J Neurol2011，258，： | 1 |
| 13 | Chemistry and electrochemistry of composite LiFePO4 materials for secondary lithium batteries显示文摘 | FRANGER S BENOIT C BOURBON C CRAS F L | 2006 | Journal of Physics and Chemistry of Solids2006，67，56： | 1 |
| 14 | Ghrelin controls hippocampal spine synapse density and memory performance 显示文摘 | Diano S Farr SA Benoit SC | 2006 | Nature Meuroscience2006，9，3： | 1 |
| 15 | Effect of pH and temperature on the viscosity of texturized and Commercial whey protein dispersions 显示文摘 | Benoit S M Afizah M Nor Ruttarattanamongkol K | 2013 | International Journal of Food Properties2013，，： | 1 |
| 16 | Chemistry and electrochemistry of composite LiFePO4 materials for secondary lithium batteries显示文摘 | Franger S Benoit C Bourbon C | | 0，，5： | 1 |
| 17 | The precise location and nature of the nerves to the male human urethra: histological and immunohistochemical studies with three-di- mensional reconstruction显示文摘 | Karam I Droupy S Abd-Alsamad I Korbage A Uhl JF Benoit G | 2005 | Eur Urol2005，48，： | 1 |
| 18 | Pesticide desorption from soils facilitated by dissolved organic matter coming from composts: ex- perimental data and modelling approach显示文摘 | Barriuso E Andrades M S Benoit P | 2011 | Biogeochemistry2011，106，： | 1 |
| 19 | Crohn disease-associated adherent-invasive E. coli bacteria target mouse and human Peyer’s patches via long polar fimbriae显示文摘 | Chassaing Benoit Rolhion Nathalie de Vallée Amélie Salim Sa’ad Y Prorok-Hamon Maelle Neut Christel Campbell Batty J S?derholm Johan D Hugot Jean-Pierre Colombel Jean-Frédéric Darfeuille-Michaud Arlette | 2011 | Journal of Clinical Investigation2011，，3： | 1 |
| 20 | Chemistry and electrochemistry of composite LiFePO4 materials for secondary lithium batteries显示文摘 | Franger S Benoit C Bourbon C | 2006 | Journal of Physics and Chemistry of Solids2006，67，56： | 1 |
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