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| 1 | Extracellular Signal-Regulated Kinase in Nucleus Accumbens Mediates Propofol Self-Administration in Rats显示文摘Clinical and animal studies have indicated that propofol has potential for abuse,but the specific neurobiological mechanism underlying propofol reward is not fully understood.The purpose of this study was to investigate the role of extracellular signal-regulated kinase(ERK) signal transduction pathways in the nucleus accumbens(NAc) in propofol self-administration.We tested the expression of p-ERK in the NAc following the maintenance of propofol self-administration in rats.We also assessed the effect of administration of SCH23390,an antagonist of the D1 dopamine receptor,on the expression of p-ERK in the NAc in propofol self-administering rats,and examined the effects of intra-NAc injection of U0126,an MEK inhibitor,on propofol reinforcement in rats.The results showed that the expression of p-ERK in the NAc increased significantly in rats maintained on propofol,and pre-treatment with SCH23390 inhibited the propofol selfadministration and diminished the expression of p-ERK in the NAc.Moreover,intra-NAc injection of U0126(4 μg/side) attenuated the propofol self-administration.The data suggest that ERK signal transduction pathways coupled with D1 dopamine receptors in the NAc may be involved in the maintenance of propofol self-administration and its rewarding effects. | Benfu Wang Xiaowei Yang Anna Sun Lanman Xu Sicong Wang Wenxuan Lin Miaojun Lai Huaqiang Zhu Wenhua Zhou Qingquan Lian | 2016 | Neuroscience Bulletin2016，32，6： | 12 |
| 2 | Surface characteristics of rapidly solidified nickel-based superalloy pow-ders prepared by PREP显示文摘The surface microstructure and the surface segregation of FGH95 nickel-based superalloy powders prepared through plasma rotating electrode processing (PREP) have been investigated by using SEM and AES. The results indicate that the surface microstructure of powders changes fiom dendrite into cellular structure as the particle size of powders decrease, and the predominant precipitates solidified on the particle surfaces were identified as MC' type carbides enriched with Nb and Ti. It was also indicated that along with the depth of particle surfaces, the segregation layer of S, C and O elements are thick, and that of Ti, Cr elements are thin for large size powders while they are in reverse for median size particles. | CHEN Huanming , HU Benfu , and LI Huiying1) School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, China2) School of Physics and Electrical Information Engineering, Ningxia University, Yinchuan 750021, China | 2003 | Rare Metals2003，22，4： | 6 |
| 3 | Microstructure Stability of V and Ta Microalloyed 12%Cr Reduced Activation Ferrite/Martensite Steel during Long-term Aging at 650℃显示文摘In view of developing novel alloys for applications in supercritical water-cooled reactor fuel cladding and in-core components, a 12%Cr reduced activation ferrite/martensite(RAFM) steel with good corrosion resistance and irradiation performance was developed. V and Ta were added to form fine MX type carbonitrides and enhance the high temperature creep rupture strength. Microstructure stability of the steel during long-term aging at 650 C was studied experimentally combined with the simulation of ThermoCalc and DICTRA software. The results show that the precipitates in the steel during long-term aging contain M23C6, MX and Laves phase. M23C6 carbides play a major role in the stabilization of the tempered martensite lath structure by exerting a large Zener pinning force as compared with MX and Laves phase.Adding V and Ta in the steel can not only promote MX precipitation, but also refine M23C6 carbides and thus improve the thermal stability of lath/subgrains, which is beneficial to the improvement of high temperature microstructure stability of the 12%Cr RAFM steel. | Xiang Xiao Guoquan Liu Benfu Hu Jinsan Wang Wenbin Ma | 2015 | Journal of Materials Science & Technology2015，31，3： | 5 |
| 4 | Hot deformation behavior of FGH96 superalloys显示文摘The hot deformation behavior of FGH96 superalloys at 1070-1170°C and 5×10?4-2×10?1 s?1 were investigated by means of the isothermal compression tests at a Gleeble-1500 thermal mechanical simulator. The results show that dynamic recovery acts as the main softening mechanism below 2×10?3 s?1, whereas dynamic recrystallization acts as the main softening mechanism above 2×10?3 s?1 during deformation; the temperature increase caused by the deformation and the corresponding softening stress is negligible; the thermal-mechanical constitutive model to describe the hot deformation behavior is given, and the value of the apparent deformation activation energy (Qdef ) is determined to be 354.93 kJ/mol. | Jiantao Liu Guoquan Liu Benfu Hu Yuepeng Song Ziran Qin Yiwen Zhang | 2006 | Journal of University of Science and Technology Beijing2006，13，4： | 4 |
| 5 | Effect of solution cooling rate on the γ′ precipitation behaviors of a Ni-base P/M superalloy显示文摘The effect of cooling rate on the cooling γ′ precipitation behaviors was investigated in a Ni-base powder/metallurgy (P/M) superalloy (FGH4096). The empirical equations were established between the cooling rate and the average sizes of secondary and tertiary γ′ precipitates within grains and tertiary γ′ precipitates at grain boundaries, as well as the apparent width of grain boundaries. The results show that the average sizes of secondary or tertiary γ′ precipitates are inversely correlated with the cooling rate. The shape of secondary γ′ precipitates within grains changes from butterfly-like to spherical with the increase of cooling rate, but all the tertiary γ′ precipitates formed are spherical in shape. It is also found that tertiary γ′ may be precipitated in the latter part of the cooling cycle only if the cooling rate is not faster than 4.3°C/s, and the apparent width of grain boundaries decreases linearly with the in-crease of cooling rate. | Gaofeng Tian Chengchang Jia Ying Wen Benfu Hu | 2008 | Journal of University of Science and Technology Beijing2008，15，6： | 3 |
| 6 | Cooling γ′ precipitation behavior and strengthening in powder metallurgy su-peralloy FGH4096显示文摘Two cooling schemes (continuous cooling and interrupted cooling tests) were applied to investigate the cooling γ′ precipitation behavior in powder metallurgy superalloy FGH4096. The effect of cooling rate on cooling γ′ precipitation and the development of γ′ precipitates during cooling process were involved in this study. The ultimate tensile strength (UTS) of the specimens in various cooling circumstances was tested. The experiential equations were obtained between the average sizes of secondary and tertiary γ′ precipitates, the strength, and cooling rate. The results show that they are inversely correlated with the cooling rate as well as the grain boundary changes from serrated to straight, the shape of secondary γ′ precipitates changes from irregular cuboidal to spherical, while the formed tertiary γ′ precipitates are always spherical. The interrupted cooling tests show that the average size of secondary γ′ precipitates increases as a linear function of interrupt temperature for a fixed cooling rate of 24°C/min. The strength first decreases and then increases against interrupt temperature, which is fundamentally caused by the multistage nucleation of γ′ precipitates during cooling process. | TIAN Gaofeng JIA Chengchang WEN Yin LIU Guoquan HU Benfu | 2008 | Rare Metals2008，27，4： | 3 |
| 7 | SOLIDIFICATION MICROSTRUCTURE OF Ni-BASE SUPERALLOY POWDER显示文摘The solidification microstructure and phase composition of Ni-base superalloy FGH95 pow-der with different mesh size have been investigated.The structure transition was found fromdendrite in major into cellular structure as the powder size reduces and the cooling rate in-creases.The predominant phase was identified as MC-type carbide,with differentmorphologies,which may be related to their composition and the condition ofsolidification.Minor phases,such as boride,Laves and primary γ’ are also present as ac-companiments of the carbide. | HU Benfu LI Huiying WU Chengjian ZHANG Shouhua University of Science and Technology Beijing,Beijing,China Associate Professor,Dept.of Material Science and Engineering,University of Science and technology Beijing,Beijing 100083,China. | 1991 | Acta Metallurgica Sinica(English Letters)1991，4，2： | 2 |
| 8 | THREE ASPECTS ON SOLVING QUEUING SERVICE SYSTEM IN SHANGHAI WORLD EXPO显示文摘This paper analyzes the queuing problem that was experienced during the Shanghai World Expo of2010.The queuing problem will be discussed at three levels.The three levels include the physical,psychological,and social aspects of the queuing problem.The collective behavior of visitors is studied through analyzing the information from the different sources,such as,the network of electronic eyes,the evaluation platform based on mobile phone system and the Internet.A hybrid information network technology is implemented.Based on the Wuli-Shili-Renli(WSR) system methodology,a new theoretical analysis framework for the queuing problem is proposed. | Jifa GU Shanying XU Yong FANG Kan SHI Benfu LV Geng PENG Bo WANG Li SONG Rong XIE | 2013 | Journal of Systems Science and Systems Engineering2013，22，3： | 2 |
| 9 | Stability of γ′ multimodal microstructure in a Ni-based powder metallurgy superalloy显示文摘Multimodal size distribution of γ′ phase was obtained in a slow-cooling experiment following supersolvus solution treatment(1191°C). The morphology of the secondary γ′ particles exhibited splitting and protrusion instabilities. In the subsequent aging process(815°C), reverse coarsening was observed, i.e., the average precipitate size decreased with increasing aging time.Reverse coarsening slows the coarsening rate of the precipitates, increases the hardness of the alloy, and greatly improves the morphological stability of the γ′ phase. | ZHANG Ming LIU GuoQuan WANG Hao HU BenFu | 2018 | Science China(Technological Sciences)2018，61，12： | 2 |
| 10 | Randomized trial of autologous bone marrow mesenchymal stem cells transplantation for hepatitis B virus cirrhosis: Regulation of T reg/ T h17 cells显示文摘 | Lanman Xu Yuewen Gong Benfu Wang Keqing Shi Yijun Hou Liping Wang Zuo Lin Yixiang Han Lu Lu Dazhi Chen Xiuli Lin Qiqiang Zeng Wenke Feng Yongping Chen | 2014 | J Gastroenterol Hepatol2014，，8： | 1 |
| 11 | Glucose-6-phosphate dehydrogenase neutralizes stresses by supporting reductive glutamine metabolism and AMPK activation显示文摘Dear Editor,Glucose-6-phosphate dehydrogenase(G6PD)is the rate-limiting enzyme in the oxidative pentose phosphate pathway(oxPPP)that can generate cytosolic NADPH(Fig.1a)for biosynthesis and oxidative defence.Here,we reveal a previously unidentified function of G6PD.It,even the natural G6PD deficiency-associated mutant without the activity to maintain the normal oxPPP,can antagonize the stresses by supporting the reductive glutamine metabolism and AMPK activation,independently of the NADPH generation by the oxPPP. | Benfu Zhong Dewei Jiang Yang Hong Lifang Li Li Qiu Ronghui Yang Xiaohan Jin Yawen Song Ceshi Chen Binghui Li | 2021 | Signal Transduction and Targeted Therapy2021，6，3： | 1 |
| 12 | Hot compressive deformation behavior of a new hot isostatically pressed Ni–Cr–Co based powder metallurgy superalloy显示文摘 | Kai Wu Guoquan Liu Benfu Hu Feng Li Yiwen Zhang Yu Tao Jiantao Liu | 2010 | Materials and Design2010，，： | 1 |
| 13 | Damage behaviour in an electron/helium dual-beam irradiated Fe-Cr-Mn(W,V)alloy显示文摘 | HU Benfu Kinoshita H | 1998 | J Nucl Mater1998，25，17： | 1 |
| 14 | Carbide phases in Ni- based P/M superalloy显示文摘 | Hu Benfu Zhang Shouhua | 1994 | Journal of University of Science & Technology Beijing1994，1，1： | 1 |
| 15 | Analysis on the Water-saving Irrigation Technique Based on the Perspective of Food Safety显示文摘The paper analyzed the important role of water saving in protecting the food safety,introduced the present development of agricultural water-saving technique,pointed out the potential risks of water resources,and proposed the future development of water-saving irrigation. | Jinpeng HUANG Benfu WANG Bende ZHOU | 2014 | Asian Agricultural Research2014，6，8： | 1 |
| 16 | Numerical calculation on temperature field of FGH95 alloy droplet during rapid solidification显示文摘The temperature field of FGH95 alloy droplet atomized by plasma rotating electrode processing (PREP) during solidifica-tion has been calculated through numerical analysis based on equivalent sensible heat capacity method. And thus the relational cul-ves among temperature gradient of solid-liquid interface, moving velocity of solid-liquid interface and solid fraction during solidifi-cation have been presented. The results indicate that the relation between average temperature gradient of solid-liquid interface anddroplet size, and the relation between average moving velocity of solid-liquid interface and droplet size can be expressed during solidification. | Huanming Chen and Benfu Hu Materials Science and Engineering School, University of Science and Technology Beijing, Beijing 100083,China Physics and Electrical Information Engineering School, Ningxia University, Yinchuan 750021,China | 2003 | Journal of University of Science and Technology Beijing2003，10，3： | 1 |
| 17 | The General Model of Influenza Epidemics Surveillance Using Search Engine Data显示文摘 | Liu Fan Liu Ying and Lv Benfu | 2010 | Working paper2010，，： | 1 |
| 18 | Orbital chemodectoma: Clinic and pathologic analysis of 2 cases显示文摘 | Wu Benfu | 1981 | Chin Med J1981，94，： | 1 |
| 19 | Stability Analysis and Measure Study of Tobacco Farmers in the Mountainous Area of Western Hubei显示文摘Through the investigation,this paper analyzes the important restricting factors for the tobacco farmers in Enshi Badong mountainous area from 2018 to 2021,including the age structure,the loss situation,the number of years of planting tobacco,the scale of planting tobacco and the benefit of planting tobacco.This paper puts forward some corresponding measures and suggestions,such as cultivating the team of professional tobacco farmers,establishing the team of young tobacco farmers,expanding professional services,developing'tobacco plus'diversified industries,and popularizing suitable agricultural machinery in mountainous areas in order to effectively improve the stability of the team of tobacco farmers. | Fanwen FENG Benfu LIU Jing HUANG Gaohang CHEN Shenghui TUO Yongjun CHEN Yong WANG | 2022 | Asian Agricultural Research2022，14，11： | 0 |
| 20 | 用 3-PBIB (2 ) 设计的到构造的有限几何学和 3 设计 | Yang Benfu (1) | 1994 | Applied Mathematics(A Journal of Chinese Universities)1994，9，3： | 0 |
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