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| 1 | Developing More Effective Enhanced Biochar Fertilisers for Improvement of Pepper Yield and Quality显示文摘Utilization of biochar at high application rates can increase soil C and crop yields, decrease greenhouse gas emissions and reduce nutrient run-off from soils. However, the high application rate of 10 t ha-1may not return a profit to the farmer due to the high cost of biochar. In this study biochar was modified through pre-treating the biomass and post-treating with phosphoric acid, minerals and different chemical fertilisers to study the effects of two new enhanced biochar fertilisers on the yield and quality of green pepper in a field experiment with 5 fertilisation treatments and 3 replications. The two new biochar fertilisers significantly(P < 0.05) increased the yield of green pepper(11.33–11.47 t ha-1), compared with the conventional chemical fertiliser(9.72 t ha-1). The biochar fertiliser treatments improved the vitamin C content of green pepper from 236.99 to 278.28 mg kg-1, and also significantly(P < 0.05) reduced the nitrate content from 132.32 to 101.92 mg kg-1, compared with chemical fertiliser. This study indicated that, compared to the use of conventional chemical fertiliser, all of the biochar fertiliser treatments could significantly improve the yield and quality of green pepper. | YAO Chunxue Stephen JOSEPH LI Lianqing PAN Genxing Yun LIN Paul MUNROE Ben PACE Sarasadat TAHERYMOOSAVI Lukas VAN ZWIETEN Torsten THOMAS Shaun NIELSEN Jun YE Scott DONNE | 2015 | Pedosphere2015，25，5： | 8 |
| 2 | Phosphorylation switch modulates the interdigitated pattern of PIN1 localization and cell expansion in Arabidopsis leaf epidermis显示文摘在多细胞的纸巾以内,房间可以并列地形成一单个或多重的极的轴,而是它是不清楚的普通机制是否管理极的轴形成的不同类型。大头针蛋白质的 phosphorylation 地位,被 PINOID (PID ) 蛋白质 kinase 和 PP2A 蛋白质磷酸酶直接影响,被知道在根和射击顶的双极的房间调整大头针本地化的顶端基础的极性。这里,我们提供证据 phosphorylation 调停地位的大头针极性开关广泛地被用来与交错的脑叶和缩进包括多极的人行道房间(PC ) 在 Arabidopsis 调制细胞的进程。当 FYPP1 基因,编码称为联系 phytochrome 的 serine/threonine 蛋白质磷酸酶的 PP2A,被击倒时或当 PID 基因是 overexpressed (35S::PID ) 时, PC interdigitation 的度也极大地被减少。这些基因修正引起了 PIN1 本地化从脑叶切换到缩进区域。PP2A 和 PID 调停了 PIN1 本地化切换惊人地类似于他们在另外的房间的大头针蛋白质的顶端基础的极性开关的规定。我们的调查结果为 PIN1 极性形成,在织物 / 器官两个都为模式形成是关键的一个基本细胞的过程和细胞的层次的规定建议普通机制。 | Hongjiang Li Deshu Lin Pankaj Dhonukshe Shingo Nagawa Dandan Chen Jifi Friml Ben Scheres Hongwei Guo Zhenbiao Yang | 2011 | Cell Research2011，21，6： | 7 |
| 3 | Endocrine Disruption Activity of 30-day Dietary Exposure to Decabromodiphenyl Ethane in Balb/C Mouse显示文摘Objective This study aimed to evaluate the hepatotoxicity,metabolic disturbance activity and endocrine disrupting activity of mice treated by Decabromodiphenyl ethane(DBDPE).Methods In this study,Balb/C mice were treated orally by gavage with various doses of DBDPE.After 30 days of treatment,mice were sacrificed; blood,livers and thyroid glands were obtained,and hepatic microsomes were isolated.Biochemical parameters including 8 clinical chemistry parameters,blood glucose and hormone levels including insulin and thyroid hormone were assayed.The effects of DBDPE on hepatic cytochrome P450(CYP) levels and activities and uridinediphosphate-glucuronosyltransferase(UDPGT) activities were investigated.Liver and thyroid glands were observed.Results There were no obvious signs of toxicity and no significant treatment effect on body weight,or liver-to-body weight ratios between treatment groups.The levels of ALT and AST of higher dose treatment groups were markedly increased.Blood glucose levels of treatment groups were higher than those of control group.There was also an induction in TSH,T3,and f T3.UDPGT,PROD,and EROD activities were found to have been increased significantly in the high dose group.Histopathologic liver changes were characterized by hepatocyte hypertrophy and cytoplasmic vacuolization.Our findings suggest that DBDPE can cause a certain degree of mouse liver damage and insufficiency.Conclusion DBDPE has the activity of endocrine disruptors in Bal/C mice,which may induce drug-metabolizing enzymes including CYPs and UDPGT,and interfere with thyroid hormone levels mediated by Ah R and CAR signaling pathways.Endocrine disrupting activity of DBDPE could also affect the glucose metabolism homeostasis. | SUN Ru Bao SHANG Shuai ZHANG Wei LIN Ben Cheng WANG Qiang SHI Yun XI Zhu Ge | 2018 | Biomedical and Environmental Sciences2018，31，1： | 7 |
| 4 | Homogeneous bottom-growth of lithium metal anode enabled by double-gradient lithiophilic skeleton显示文摘Lithium(Li) metal is considered as the most promising anode material for the next-generation high performance Li batteries.However,the uncontrollable dendritic growth impedes its commercial application.Herein,we design a 3 D Si@carbon nanofibers(CNFs)@ZnO-ZnO-Cu skeleton(SCZ) for guiding the homogeneous bottom-growth of Li metal.The top LixSi@CNFs and bottom LiyZn@CNFs layers could form conductivity and overpotential gradient to avoid the 'top-growth' of Li metal.Moreover,the top lithiophilic LixSi@CNFs layer could regulate the nucleation and deposition of Li-ions even if the lithium dendrites grow out of the skeleton under high capacity Li deposition(30 mAh cm^(-2)).As a result,the SCZ-Li||LiFePO_(4) full cell delivers a high capacity of ~104 mAh g^(-1)(~94.82% capacity retention) after 2000 cycles at 5 C, elucidating the potential application of the 3 D double-gradient Li metal composite anode. | Li Zhang Hongfei Zheng Ben Liu Qingshui Xie Qiulin Chen Liang Lin Jie Lin Baihua Qu Laisen Wang Dong-Liang Peng | 2021 | Journal of Energy Chemistry2021，30，6： | 5 |
| 5 | Online schedule for autonomy of multiple unmanned aerial vehicles显示文摘An online rectangle based scheduling algorithm(RSA) is developed to improve autonomy of multiple unmanned aerial vehicles(UAVs) to search a field of forest together. The purposes of RSA are to online decide the number of the UAVs to be assigned and to schedule the path for the assigned UAVs to search the missed areas resulted from the previous search. The main ideas of RSA are to cover each separated zone of the missed areas with a rectangle and then to schedule the path to search the rectangles. Thus, RSA is robust against the unknown shapes and sizes of the missed areas. The forest search is applied to verify the online RSA in simulation. The simulation results demonstrate that the online RSA is successful to decide the number of the UAVs to be assigned and to schedule the path for the assigned UAVs to search the missed areas. | Kemao PENG Feng LIN Ben M.CHEN | 2017 | Science China(Information Sciences)2017，60，7： | 5 |
| 6 | The desumoylating enzyme sentrin-specific protease 3 contributes to myocardial ischemia reperfusion injury显示文摘Sentrin-specific protease 3(SENP3), a member of the desumoylating enzyme family, is known as a redox sensor and could regulate multiple cellular signaling pathways. However, its implication in myocardial ischemia reperfusion(MIR) injury is unclear. Here, we observed that SENP3 was expressed and upregulated in the mouse heart depending on reactive oxygen species(ROS) production in response to MIR injury. By utilizing si RNA-mediated cardiac specific gene silencing, SENP3 knockdown was demonstrated to significantly reduce MIR-induced infarct size and improve cardiac function. Mechanistic studies indicated that SENP3 silencing ameliorated myocardial apoptosis mainly via suppression of endoplasmic reticulum(ER) stress and mitochondrial-mediated apoptosis pathways. By contrast, adenovirusmediated cardiac SENP3 overexpression significantly exaggerated MIR injury. Further molecular analysis revealed that SENP3 promoted mitochondrial translocation of dynamin-related protein 1(Drp1) in reperfused myocardium. In addition, mitochondrial division inhibitor-1(Mdivi-1), a pharmacological inhibitor of Drp1, significantly attenuated the exaggerated mitochondrial abnormality and cardiac injury by SENP3 overexpression after MIR injury. Taken together, we provide the first direct evidence that SENP3 upregulation pivotally contributes to MIR injury in a Drp1-dependent manner, and suggest that SENP3 suppression may hold therapeutic promise for constraining MIR injury. | Lingchen Gao Yichao Zhao Jie He Yang Yan Longwei Xu Nan Lin Qingqi Ji Renyang Tong Yanan Fu Yu Gao Yuanyuan Su Ancai Yuan Ben He Jun Pu | 2018 | Journal of Genetics and Genomics2018，45，3： | 5 |
| 7 | Aggregation-induced emission (ALE) dye loaded polymer nanoparticles for gene silencing in pancreatic cancer and their in vitro and in vivo biocompatibility evaluation显示文摘 | Rui Hu Chengbin Yang Yucheng Wang Guimiao Lin Wei Qin Qingling Ouyang Wing-Cheung Law Quoc Toan Nguyen Ho Sup Yoon Xiaomei Wang Ken-Tye Yong Ben Zhong Tang | 2015 | Nano Research2015，8，5： | 4 |
| 8 | Exposure to PM2.5 Enhances the PI3K/AKT Signaling and Malignancy of ERα Expression-dependent Non-small Cell Lung Carcinoma显示文摘Atmospheric particulate matter(PM)2.5 is a major carcinogen and is associated with an increased risk of developing various cancers and pulmonary fibrous diseases[1-2].Non-small cell lung cancer(NSCLC)is the major type of lung cancer with high morbidity and mortality rates.Epidemiological studies report that the incidence of NSCLC,particularly adenocarcinoma,significantly differs with the gender[3].Female patients with NSCLC have unique epidemiologic characteristics,imaging profiles,clinical manifestations,and pathological characteristics[4]. | TIAN Lei LI Ying LIU Huan Liang LAI Wen Qing SHI Yue LIU Xiao Hua XI Zhu Ge LIN Ben Cheng | 2021 | Biomedical and Environmental Sciences2021，34，4： | 3 |
| 9 | 1-((12-Bromododecyl)oxy)-4-((4-(4-pentylcyclohexyl)phenyl)ethynyl) benzene: Liquid crystal with aggregation-induced emission characteristics显示文摘The luminescent liquid crystals (LLCs) are expected to solve the conflicts between the aggregation caused quenching and the requirement of aggregation or self-organization for LCs. Herein, we developed a new strategy of applying aggregation-induced emission (AIE) phenomenon to the molecular design of LCs towards LLCs. In this report, a calamitic liquid crystal based on tolane with AIE characteristics was successfully synthesized and the chemical structure was characterized by 1H, 13C NMR, and matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) high-resolution mass spectra. The fluorescence behavior was studied by fluorescence spectroscopy and the liquid crystal phase behaviors were investigated by differential scanning calorimetry (DSC), polarized optical microscopy (POM). The crystal structure was obtained by X-ray diffraction crystallography with P1 space group. Results demonstrated that the sample was AIE active and the LC phases sequence during cooling was nematic, smectic C and smectic B phase. | CHEN YaFei LIN JieSheng YUAN WangZhang YU ZhenQiang LAM Jacky WingYip TANG Ben Zhong | 2013 | Science China Chemistry2013，56，9： | 3 |
| 10 | Feeding Biochar to Cows:An Innovative Solution for Improving Soil Fertility and Farm Productivity显示文摘Addition of biochar produced through thermal decomposition of biomass has been seen as a strategy to improve soils and to sequester carbon(C), but wide scale implementation of the technology requires to devise innovative profitable solutions. To develop biochar utilisation with an integrated system approach, an innovative program was implemented in 2012 on a 53-ha farm in Western Australia to determine the costs and benefits of integrating biochar with animal husbandry and improvement of pastures. Biochar was mixed with molasses and fed directly to cows. The dung-biochar mixture was incorporated into the soil profile by dung beetles.We studied the changes in soil properties over 3 years. Biochar extracted from fresh dung and from the soil to a depth of 40 cm was characterised. A preliminary financial analysis of the costs and benefits of this integrated approach was also undertaken. The preliminary investigation results suggested that this strategy was effective in improving soil properties and increasing returns to the farmer. It was also concluded that the biochar adsorbed nutrients from the cow's gut and from the dung. Dung beetles could transport this nutrient-rich biochar into the soil profile. There was little evidence that the recalcitrant component of the biochar was reduced through reactions inside the gut or on/in the soil. Further research is required to quantify the long-term impact of integrating biochar and dung beetles into the rearing of cows. | Stephen JOSEPH Doug POW Kathy DAWSON David R.G.MITCHELL Aditya RAWAL James HOOK Sarasadat TAHERYMOOSAVI Lukas VAN ZWIETEN Joshua RUST Scott DONNE Paul MUNROE Ben PACE Ellen GRABER Torsten THOMAS Shaun NIELSEN Jun YE Yun LIN PAN Genxing LI Lianqing Zakaria M.SOLAIMAN | 2015 | Pedosphere2015，25，5： | 2 |
| 11 | Salivary microbiota may predict the presence of esophageal squamous cell carcinoma显示文摘The aim is to explore the predictive value of salivary bacteria for the presence of esophageal squamous cell carcinoma (ESCC). Saliva samples were obtained from 178 patients with ESCC and 101 healthy controls, and allocated to screening and verification cohorts, respectively. In the screening phase, after saliva DNA was extracted, 16S rRNA V4 regions of salivary bacteria were amplified by polymerase chain reaction (PCR) with high-throughput sequencing. Highly expressed target bacteria were screened by Operational Taxonomic Units clustering, species annotation and microbial diversity assessment. In the verification phase, the expression levels of target bacteria identified in the screening phase were verified by absolute quantitative PCR (Q-PCR). Receiver operating characteristic (ROC) curves were plotted to investigate the predictive value of target salivary bacteria. LEfSe analysis revealed higher proportions of Fusobacterium, Streptococcus and Porphyromonas, and Q-PCR assay showed significantly higher numbers of Streptococcus salivarius, Fusobacterium nucleatum and Porphyromonas gingivalis in patients with ESCC, when compared with healthy controls (all P < 0.05). The areas under the ROC curves for Streptococcus salivarius, Fusobacterium nucleatum, Porphyromonas gingivalis and the combination of the three bacteria for predicting patients with ESCC were 69%, 56.5%, 61.8% and 76.4%, respectively. The sensitivities corresponding to cutoff value were 69.3%, 22.7%, 35.2% and 86.4%, respectively, and the matched specificity were 78.4%, 96.1%, 90.2% and 58.8%, respectively. These highly expressed Streptococcus salivarius, Fusobacterium nucleatum and Porphyromonas gingivalis in the saliva, alone or in combination, indicate their predictive value for ESCC. | Junmin Wei Ruifeng Li Yanxian Lu Fan Meng Bohong Xian Xiaorong Lai Xiayi Lin Yu Deng Dongyang Yang Huabin Zhang Liangfang Li Xiaosong Ben Guibin Qiao Wanwei Liu Zijun Li | 2022 | Genes & Diseases2022，9，4： | 2 |
| 12 | Revolution of vitamin E production by starting from microbial fermented farnesene to isophytol显示文摘Vitamin E is one of the most widely used vitamins.In the classical commercial synthesis of vitamin E(a-tocopherol),the chemical synthesis of isophytol is the key technical barrier.Here,we establish a new process for isophytol synthesis from microbial fermented farnesene.To achieve an efficient pathway for farnesene production,Saccharomyces cerevisiae was selected as the host strain.First,b-farnesene synthase genes from different sources were screened,and through protein engineering and system metabolic engineering. | Ziling Ye Bin Shi Yanglei Huang Tian Ma Zilei Xiang Ben Hu Zhaolin Kuang Man Huang Xiaoying Lin Zhu Tian Zixin Deng Kun Shen Tiangang Liu | 2022 | The Innovation2022，3，3： | 2 |
| 13 | Anα/βhydrolase family member negatively regulates salt tolerance but promotes flowering through three distinct functions in rice显示文摘Ongoing soil salinization drastically threatens crop growth,development,and yield worldwide.It is therefore crucial that we improve salt tolerance in rice by exploiting natural genetic variation.However,many salt-responsive genes confer undesirable phenotypes and therefore cannot be effectively applied to practical agricultural production.In this study,we identified a quantitative trait locus for salt tolerance from the African rice species Oryza glaberrima and named it as Salt Tolerance and Heading Date 1(STH1).We found that STH1 regulates fatty acid metabolic homeostasis,probably by catalyzing the hydrolytic degradation of fatty acids,which contributes to salt tolerance.Meanwhile,we demonstrated that STH1 forms a protein complex with D3 and a vital regulatory factor in salt tolerance,OsHAL3,to regulate the protein abundance of OsHAL3 via the 26S proteasome pathway.Furthermore,we revealed that STH1 also serves as a co-activator with the floral integrator gene Heading date 1 to balance the expression of the florigen gene Heading date 3a under different circumstances,thus coordinating the regulation of salt tolerance and heading date.Notably,the allele of STH1 associated with enhanced salt tolerance and high yield is found in some African rice accessions but barely in Asian cultivars.Introgression of the STH1HP46 allele from African rice into modern rice cultivars is a desirable approach for boosting grain yield under salt stress.Collectively,our discoveries not only provide conceptual advances on the mechanisms of salt tolerance and synergetic regulation between salt tolerance and flowering time but also offer potential strategies to overcome the challenges resulted from increasingly serious soil salinization that many crops are facing. | You-Huang Xiang Jia-Jun Yu Ben Liao Jun-Xiang Shan Wang-Wei Ye Nai-Qian Dong Tao Guo Yi Kan Hai Zhang Yi-Bing Yang Ya-Chao Li Huai-Yu Zhao Hong-Xiao Yu Zi-Qi Lu Hong-Xuan Lin | 2022 | Molecular Plant2022，15，12： | 2 |
| 14 | Revealing complex optical phenomena through vectorial metrics显示文摘Advances in vectorial polarization-resolved imaging are bringing new capabilities to applications ranging from fundamental physics through to clinical diagnosis.Imaging polarimetry requires determination of the Mueller matrix(MM)at every point,providing a complete description of an object’s vectorial properties.Despite forming a comprehensive representation,the MM does not usually provide easily interpretable information about the object’s internal structure.Certain simpler vectorial metrics are derived from subsets of the MM elements.These metrics permit extraction of signatures that provide direct indicators of hidden optical properties of complex systems,while featuring an intriguing asymmetry about what information can or cannot be inferred via these metrics.We harness such characteristics to reveal the spin Hall effect of light,infer microscopic structure within laser-written photonic waveguides,and conduct rapid pathological diagnosis through analysis of healthy and cancerous tissue.This provides new insight for the broader usage of such asymmetric inferred vectorial information. | Chao He Jintao Chang Patrick S.Salter Yuanxing Shen Ben Dai Pengcheng Li Yihan Jin Samlan Chandran Thodik Mengmeng Li Aziz Tariq Jingyu Wang Jacopo Antonello Yang Dong Ji Qi Jianyu Lin Daniel S.Elson Min Zhang Honghui He Hui Ma Martin J.Booth | 2022 | Advanced Photonics2022，4，2： | 2 |
| 15 | Guidelines for the Diagnosis and Treatment of Rosacea in China(2021 Edition)显示文摘Rosacea is a chronic inflammatory skin disease that primarily affects the centrofacial areas and mainly manifests as recurrent flushing and erythema.In recent years,there has been progress in the understanding of the diagnosis and treatment of rosacea.Therefore,a group of dermatological experts updated the guidelines based on the 2016 expert consensus statement on rosacea diagnosis and treatment in China.These new guidelines propose diagnostic criteria for rosacea at different sites to further standardize the diagnosis and treatment of rosacea in China. | Rosacea Research Center,Chinese Society of Dermatology Rosacea Professional Committee,Chinese Dermatologist Association Heng Gu Fei Hao Wei He Dan Jian Zhe Jian Xian Jiang Qiang Ju Xiao-Jing Kang Wei Lai Heng-Jin Li Ji Li Tie-Nan Li Xin-Yu Lin Wei Liu Xiao-Hua Tao Ben Wang Hong-Fu Xie Hong-Hui Xu Yang Xu Shu-Xian Yan Jie Yang Bo Yu | 2021 | International Journal of Dermatology and Venereology2021，4，4： | 2 |
| 16 | Impact of government and industrial agglomeration on industrial land prices: A Taiwanese case study显示文摘 | Shu-Wen Lin Tai-Ming Ben | 2009 | Habitat International2009，，4： | 1 |
| 17 | Impact of government and industrial agglomeration on industrial land prices:A Taiwanese case study显示文摘 | LIN Shu-wen BEN Tai-Ming | 2009 | Habitat International2009，33，4： | 1 |
| 18 | Theranostic hyaluronic acid prodrug micelles with aggregation- induced emission characteristics for targeted drug delivery显示文摘Theranostic hyaluronic acid(HA) prodrug micelles with pH-responsive drug release and aggregation-induced emission(AIE)properties were prepared by chemical graft of biomimetic phosphorylcholine(PC), anticancer drug doxorubicin(DOX) and AIE fluorogen tetraphenylene(TPE) to the HA backbone. DOX was conjugated to the HA backbone by a hydrazone bond which can be hydrolyzed under acidic environment and result in pH-triggered smart release of DOX. The TPE units with typical AIE characteristics were applied for real time drug tracking in cancer cells. The HA-based prodrugs could self-assemble into micelles in aqueous solution as confirmed by the dynamic light scattering(DLS) and transmission electron microscopy(TEM). The intracellular distribution of HA prodrug micelles could be clearly observed by fluorescence microscopy based on the strong fluorescence of TPE. Moreover, after treated with the micelles, stronger fluorescence of TPE in CD44 overexpressed MDA-MB-231 cancer cells was observed, compared to the CD44 negative cell line, NIH3T3 cells, suggesting efficient cell uptake of HA prodrug micelles by receptor-mediated endocytosis. The cell viability results indicated that the prodrug micelles could inhibit the proliferation of the cancer cells effectively. Such pH-triggered theranostic drug delivery system with AIE features can provide a new platform for targeted and image-guided cancer therapy. | Lin Wang Haoke Zhang Anjun Qin Qiao Jin Ben Zhong Tang Jian Ji | 2016 | Science China Chemistry2016，59，12： | 1 |
| 19 | Throughput maximization of ad k hoe wireless networks using adaptive cooperative diversity and truncated ARQ显示文摘 | Lin Dai Khaled Ben Letaief | 2008 | 1EEE Transactions on Communica tions2008，56，11： | 1 |
| 20 | Breast cancer metastasis suppressor 1 inhibits SDF-1 alpha-induced migration of non-small cell lung cancer by decreasing CXCR4 expression显示文摘 | Yang Jiyun Zhang Ben Lin Yin | 2008 | Cancer Lett2008，269，1： | 1 |
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