|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | miR-27b inhibits gastric cancer metastasis by targeting NR2F2显示文摘增加的注意在癌症过程集中于 miRNAs 的下面规定。原子受体亚科 2 (NR2F2,也作为 COUP-TFII 知道) 涉及癌症的许多类型的发展,但是它在胃的癌症的角色留下逃犯。在这个实验, oncomine 和 Kaplan-meier 数据库表明 NR2F2 在胃的癌症是起来调整的并且高 NR2F2 表示贡献了差的幸存。MicroRNA-27b 被指向并且由在人的胃的癌症纸巾和房间的 NR2F2 下面调整。miR-27b 的宫外的表示在 vitro 并且在 vivo 禁止了胃的癌症房间增长和肿瘤生长。试金建议 miR-27b 的 overexpression 能支持 MGC-803 房间移植和侵略并且延迟他们的转移到肝。另外, miR-27b 的下面规定在 vitro 提高了 GES-1 房间增长和转移。这些调查结果表明 miR-27b 为改进病人是在胃的癌症和 biomarker 的肿瘤 suppressor 幸存。 | Qingzhao Feng Xionglin Wu Fuchao Li Beibei Ning Xiaofeng Lu Yin Zhang Ying Pan Wenxian Guan | 2017 | Protein & Cell2017，8，2： | 16 |
| 2 | sLe^(x) expression in invasive micropapillary breast carcinoma is associated with poor prognosis and can be combined with MUC1/EMA as a supplementary diagnostic indicator显示文摘Objective: Mucin 1(MUC1/EMA) and sialyl Lewis X(sLe^(x)) indicate polarity reversal in invasive micropapillary carcinoma(IMPC). The purpose of this study was to evaluate the expression of MUC1/EMA and sLe^(x) and to assess their diagnostic and prognostic value in patients with IMPC.Methods: The expression of sLe^(x) and MUC1/EMA in 100 patients with IMPC and a control group of 89 patients with invasive ductal carcinoma not otherwise specified(IDC-NOS) were analyzed with IHC. Fresh tumor tissues were collected from patients with IMPC or IDC-NOS for primary culture and immunofluorescence analysis.Results: The rate of nodal metastasis was higher in patients with IMPC than those with IDC-NOS, and IMPC cells tended to express more sLe^(x) and MUC1/EMA in the cytomembranes(the stroma-facing surfaces of the micropapillary clusters) than IDC-NOS cells. In IMPC, high cytomembrane expression of sLe^(x), but not MUC1/EMA, indicated poor prognosis. In addition, among the 100 patients with IMPC, 10 patients had sLe^(x)+/EMA-expression patterns, and 8 patients had sLe^(x)-/EMA+ expression patterns. The primary IMPC cells were suspended, non-adherent tumor cell clusters, whereas the primary IDC cells were adherent tumor cells. Immunofluorescence analysis showed that MUC1/EMA and sLe^(x) were co-expressed on the cytomembranes in IMPC cell clusters and in the cytoplasm in IDC-NOS cells.Conclusions: sLe^(x) can be used as a prognostic indicator and can be combined with MUC1/EMA as a complementary diagnostic indicator to avoid missed IMPC diagnosis. | Yawen Song Hui Sun Kailiang Wu Jianke Lyu Jingyue Zhang Feng Gu Yongjie Ma Beibei Shen Chijuan Wang Xiaojiao Chen Jing Xu Weidong Li Fangfang Liu Li Fu | 2021 | Cancer Biology & Medicine2021，18，2： | 7 |
| 3 | Metalens-integrated compact imaging devices for wide-field microscopy显示文摘Metasurfaces have demonstrated unprecedented capabilities in manipulating light with ultrathin and flat architectures.Although great progress has been made in the metasurface designs and function demonstrations,most metalenses still only work as a substitution of conventional lenses in optical settings,whose integration advantage is rarely manifested.We propose a highly integrated imaging device with silicon metalenses directly mounted on a complementary metal oxide semiconductor image sensor,whose working distance is in hundreds of micrometers.The imaging performances including resolution,signal-to-noise ratio,and field of view(FOV)are investigated.Moreover,we develop a metalens array with polarization-multiplexed dual-phase design for a wide-field microscopic imaging.This approach remarkably expands the FOV without reducing the resolution,which promises a non-limited space-bandwidth product imaging for wide-field microscopy.As a result,we demonstrate a centimeter-scale prototype for microscopic imaging,showing uniqueness of meta-design for compact integration. | Beibei Xu Hanmeng Li Shenglun Gao Xia Hu Cheng Yang Chen Chen Feng Yan Shining Zhu Tao Li | 2020 | Advanced Photonics2020，2，6： | 6 |
| 4 | Far-red light: A regulator of plant morphology and photosynthetic capacity显示文摘Plant photosynthetic capacity directly determines crop yield. Light quality regulates photosynthetic capacity. This review discusses plant responses to far-red light from the phenotypic to the molecular level, focusing specifically on the improvement of photosynthetic capacity by adjustment of photosynthetic electron transport and the path of light energy. Far-red light can also regulate leaf angle and increase plant height and leaf area, via expression of associated genes, to capture more light energy.Thus, far-red light regulates plant morphology and photosynthetic capacity. Identifying the mechanism of this regulation may lead to increased crop yields. | Tingting Tan Shenglan Li Yuanfang Fan Zhonglin Wang Muhammad Ali Raza Iram Shafiq Beibei Wang Xiaoling Wu Taiwen Yong Xiaochun Wang Yushan Wu Feng Yang Wenyu Yang | 2022 | The Crop Journal2022，10，2： | 4 |
| 5 | Different meridian tropism in three Chinese medicines: Tinglizi(Semen Lepidii Apetali), Yiyiren(Semen Coicis), Cheqianzi(Semen Plantaginis)显示文摘OBJECTIVE: To study the meridian tropism(MT) for three Chinese medicines: Tinglizi(Semen Lepidii Apetali, TLZ), Yiyiren(Semen Coicis, YYR), Cheqianzi(Semen Plantaginis, CQZ) in vivo experiments.METHODS: The extracts of TLZ,YYR, CQZ were orally administered to rats at a dose 234, 700 and 350 mg/kg, respectively. The urinary excretion rate, loss in weight of rats and the electrolyte levels in the plasma were measured, in order to assess the mechanisms of the three traditional Chinese diuretic medicines.RESULTS: TLZ, YYR and CQZ exhibited obvious diuretic effect and reduced the weight of saline-loaded animals. All the three diuretic medicines differentially reduced various serum, urinary, lung, stomach, kidney and hormonal markers, thus indicating the different mechanisms of action and a close resemblance with their different meridian as per the MT theory.CONCLUSION: Our findings suggest that the three Traditional Chinese Medicine(TCM) medicines-TLZ,YYR and CQZ-possess different Shamisen meridian.This can support the regimen of treating the same disease with different therapies in TCM theory. | Zeng Mengnan Li Miao Zhang Li Zhang Beibei Wu Guangcao Feng Weisheng Zheng Xiaoke | 2019 | Journal of Traditional Chinese Medicine2019，39，2： | 4 |
| 6 | High performance liquid chromatographic separation of eight drugs collected in Chinese Pharmacopoeia 2010 on amylose ramification chiral stationary phase显示文摘The enantiomers separation of ei ght pharmaceutical racemates collected in Chinese Pharmacopoeia 2010(Ch.P2010),including nitrendipine,felodipine,omeprazole,praziquantel,sulpiride,clenbuterol hydrochloride,verapamil hydrochloride and chlorphenamine maleate,was performed on chiral stationary phase of amylose ramification by high performance liquid chromatography(HPLC)on Chiralpak AD-H column and Chiralpak AS-H column with the mobile phase consisted of isopropanol and n-hexane.The detection wavelength and the flow rate were set at 254 nm and 0.7 mL/min,respectively.The effects of proportion of organic additives,alcohol displacer and temperature on the separation were investigated.The results indicated that eight chiral drugs were separated on chiral stationary phase of amylase ramification in normal phase chroma tographic system.The chromatographic retention and resolution of enantiomers were adjusted by factors,including the changes of the concentration of alcohol displacer in mobile phase,organic alkaline modifier and column temperature.It was shown that the resolution was improved with reducing concentration of alcohol displacer.When the concentration of organic alkaline modifier was 0.2%,the resolution and the peak shape were fairly good.Most racemates mentioned above had the best resolution at column temperature of 25℃.The best temperature should be kept unchanged in the process of separation so as to obtain stable separation results. | Yan Wang Ying Zhou Chao Ma Beibei Yang Ru Feng Yiying Zhang Jie Fu Wenjing Chen Yupeng Sun Jingyi Ma Qiming Zhang Yulin Deng Yukui Zhang Wenyi He | 2012 | Acta Pharmaceutica Sinica B2012，2，5： | 3 |
| 7 | Hormonal changes throughout puberty in boys:an observational study on the treatment outcome of congenital hypogonadotropic hypogonadism显示文摘To the Editor:It is difficult to capture the exact time of initiation of puberty in normal children,such as when breasts in girls and testicles in boys begin to grow,especially in boys.As a result,research on the detailed patterns of physical development during puberty and the cut-off values and changes of hormones at the initiation of puberty and developmental maturation is rare.It is generally believed that hormonal changes during puberty are a direct result of the stimulating effect of luteinizing hormone(LH)on initiation of puberty;[1]thus,LH is widely accepted as an indicator to evaluate initiation of puberty.However,researchers have not yet reached an agreement on the cut-off value of LH,especially in boys. | Xiaoya Ren Yuanyuan Tian Guoshuang Feng Yi Wang Beibei Zhang Bingyan Cao Jiajia Chen Chunxiu Gong | 2022 | Chinese Medical Journal2022，，3： | 2 |
| 8 | Smad5 acts as an intracellular pH messenger and maintains bioenergetic homeostasis显示文摘环境暗示和细胞内部的 bioenergetic 状态深刻地影响细胞内部的 pH (pHi ) 。一个房间怎么对 pHi 变化作出回应维持 bioenergetic 动态平衡,留下逃犯。这里,我们显示出那 Smad5,发信号的形态基因的蛋白质(BMP ) 回答到 pHi 的骨头的一个描绘得好的下游的部件变化。冷、基本或张力亢进的条件增加 pHi,它接着在 Smad5 的 MH1 域以内声言不赞成控告的氨基酸簇,推动它到细胞质的从原子核的重定位。在另一方面,加热,酸或张力减退的条件减少 pHi,堵住 Smad5 的原子出口,并且因此引起它的原子累积。环境变化和 pHi 变化导致的 Smad5 的活跃 nucleocytoplasmic shuttling 独立于 BMP 发信号, carboxyl 终点 phosphorylation 和 Smad4。另外, Smad5 的脱离引起在区别识别了的神经发展过程人的 pluripotent 干细胞建模的细胞的 bioenergetic 动态平衡和破坏正常的长期、不可逆的 dysregulation。重要地,在 Smad5 缺乏的房间的这些新陈代谢、发展的赤字能仅仅由细胞质的 Smad5 被救。细胞质的 Smad5 身体上与 hexokinase 交往 1 并且加速 glycolysis。一起,我们的调查结果显示 Smad5 充当一个 pHi 送信人并且由调整细胞质的新陈代谢的机械维持房间的 bioenergetic 动态平衡。 | Yujiang Fang Zhongliang Liu Zhenyu Chen Xiangjie Xu Mengtao Xiao Yanyan Yu Yuanyuan Zhang Xiaobai Zhang Yanhua Du Cizhong Jiang Yuzheng Zhao Yiran Wang Beibei Fan Daniel Terheyden-Keighley Yang Liu Lei Shi Yi Hui Xin Zhang Bowen Zhang Hexi Feng Lin Ma Quanbin Zhang Guohua Jin Yi Yang Bin Xiang Ling Liu Xiaoqing Zhang | 2017 | Cell Research2017，27，9： | 2 |
| 9 | Rapid and accurate detection of African swine fever virus by DNA endonuclease-targeted CRISPR trans reporter assay显示文摘The first case of African swine fever(ASF)outbreak in China was reported in a suburban pig farm in Shenyang in 2018.Since then,the rapid spread and extension of ASF has become the most serious threat fo r the swine industry.Therefore,rapid and accurate detection of African swine fever virus(ASFV)is essential to provide effective strategies to control the disease.In this study,we developed a rapid and accurate ASFV-detection method based on the DNA endonuclease-targeted CRISPR trans reporter(DETECTR)assay.By com bining recombinase polymerase am plification w ith CRISPR-Cas12a proteins,the DETECTR assay dem onstrated a m inim um detection lim it of eight copies with no cross reactivity with other swine viruses.Clinical blood samples were detected by DETECTR assay and showed 100%(30/30)agreement w ith real-tim e polymerase chain reaction assay.The rapid and accurate detection of ASFV may facilitate tim ely eradication measures and strict sanitary procedures to control and prevent the spread of ASF. | Zongjie Li Jianchao Wei Di Di Xin Wang Chenxi Li Beibei Li Yafeng Qiu Ke Liu Feng Gu Minglong Tong Shuiming Wang Xiaodong Wu Zhiyong Ma | 2020 | Acta Biochimica et Biophysica Sinica2020，52，12： | 2 |
| 10 | Energy balance and GHG emissions of cassava-based fuel ethanol using different planting modes in China显示文摘 | Beibei Liu Feng Wang Bing Zhang Jun Bi | 2012 | Energy Policy2012，，： | 1 |
| 11 | Orchestrating antigen delivery and presentation efficiency in lymph node by nanoparticle shape for immune response显示文摘Activating humoral and cellular immunity in lymph nodes(LNs)of nanoparticle-based vaccines is critical to controlling tumors.However,how the physical properties of nanovaccine carriers orchestrate antigen capture,lymphatic delivery,antigen presentation and immune response in LNs is largely unclear.Here,we manufactured gold nanoparticles(AuNPs)with the same size but different shapes(cages,rods,and stars),and loaded tumor antigen as nanovaccines to explore their disparate characters on above four areas.Results revealed that star-shaped AuNPs captured and retained more repetitive antigen epitopes.On lymphatic delivery,both rods and star-shaped nanovaccines mainly drain into the LN follicles region while cage-shaped showed stronger paracortex retention.A surprising finding is that the star-shaped nanovaccines elicited potent humoral immunity,which is mediated by CD4^(+)T helper cell and follicle B cell cooperation significantly preventing tumor growth in the prophylactic study.Interestingly,cage-shaped nanovaccines preferentially presented peptide-MHC I complexes to evoke robust CD8^(+)T cell immunity and showed the strongest therapeutic efficacy when combined with the PD-1 checkpoint inhibitor in established tumor study.These results highlight the importance of nanoparticle shape on antigen delivery and presentation for immune response in LNs,and our findings support the notion that different design strategies are required for prophylactic and therapeutic vaccines. | Hongjuan Zhao Yatong Li Beibei Zhao Cuixia Zheng Mengya Niu Qingling Song Xinxin Liu Qianhua Feng Zhenzhong Zhang Lei Wang | 2023 | Acta Pharmaceutica Sinica B2023，13，9： | 1 |
| 12 | Genome-wide signatures of the geographic expansion and breeding of soybean显示文摘Soybean is a leguminous crop that provides oil and protein. Exploring the genomic signatures of soybean evolution is crucial for breeding varieties with improved adaptability to environmental extremes. We analyzed the genome sequences of 2,214 soybeans and proposed a soybean evolutionary route, i.e., the expansion of annual wild soybean(Glycine soja Sieb. & Zucc.) from southern China and its domestication in central China, followed by the expansion and local breeding selection of its landraces(G. max(L.) Merr.). We observed that the genetic introgression in soybean landraces was mostly derived from sympatric rather than allopatric wild populations during the geographic expansion. Soybean expansion and breeding were accompanied by the positive selection of flowering time genes, including GmSPA3c. Our study sheds light on the evolutionary history of soybean and provides valuable genetic resources for its future breeding. | Ying-Hui Li Chao Qin Li Wang Chengzhi Jiao Huilong Hong Yu Tian Yanfei Li Guangnan Xing Jun Wang Yongzhe Gu Xingpeng Gao Delin Li Hongyu Li Zhangxiong Liu Xin Jing Beibei Feng Tao Zhao Rongxia Guan Yong Guo Jun Liu Zhe Yan Lijuan Zhang Tianli Ge Xiangkong Li Xiaobo Wang Hongmei Qiu Wanhai Zhang Xiaoyan Luan Yingpeng Han Dezhi Han Ruzhen Chang Yalong Guo Jochen C.Reif Scott A.Jackson Bin Liu Shilin Tian Li-juan Qiu | 2023 | Science China(Life Sciences)2023，66，2： | 1 |
| 13 | Precisely quantifying bulk transition metal valence evolution in conventional battery electrode by inverse partial fluorescence yield显示文摘Precisely quantifying transition metal(TM) redox in bulk is a key to understand the fundamental of optimizing cathode materials in secondary batteries. At present, the commonly used methods to probe TM redox are hard X-ray absorption spectroscopy(hXAS) and soft X-ray absorption spectroscopy(sXAS).However, they are both facing challenges to precisely quantify the valence states of some transition metals such as Mn. In this paper, Mn-L iPFY(inverse partial fluorescence yield) spectra extracted from Mn-L m RIXS(mapping of resonant inelastic X-ray scattering) is adopted to quantify Mn valence states. Mn-L i PFY spectra has been considered as a bulk-sensitive, non-distorted probe of TM valence states.However, the exact precision of this method is still unclear in quantifying practical battery electrodes.Herein, a series of LiMn_(2)O_(4) electrodes with different charge and discharge states are prepared. Based on their electrochemical capacity(generally considered to be very precise), the precision of Mn iPFY in quantifying bulk Mn valence state is confirmed, and the error range is unraveled. Mn-L mRIXS iPFY thus is identified as one of the best methods to quantify the bulk Mn valence state comparing with hXAS and sXAS. | Kehua Dai Weiwei Shao Beibei Zhao Wenjuan Zhang Yan Feng Wenfeng Mao Guo Ai Gao Liu Jing Mao Wanli Yang | 2022 | Journal of Energy Chemistry2022，31，6： | 1 |
| 14 | Understanding energetic disorder in electron-deficient-core-based non-fullerene solar cells显示文摘Recent advances in material design for organic solar cells(OSCs)are primarily focused on developing near-infrared nonfullerene acceptors,typically A-DA′D-A type acceptors(where A abbreviates an electron-withdrawing moiety and D,an electron-donor moiety),to achieve high external quantum efficiency while maintaining low voltage loss.However,the charge transport is still constrained by unfavorable molecular conformations,resulting in high energetic disorder and limiting the device performance.Here,a facile design strategy is reported by introducing the'wing'(alkyl chains)at the terminal of the DA′D central core of the A-DA′D-A type acceptor to achieve a favorable and ordered molecular orientation and therefore facilitate charge carrier transport.Benefitting from the reduced disorder,the electron mobilities could be significantly enhanced for the'wing'-containing molecules.By carefully changing the length of alkyl chains,the mobility of acceptor has been tuned to match with that of donor,leading to a minimized charge imbalance factor and a high fill factor(FF).We further provide useful design strategies for highly efficient OSCs with high FF. | Jun Yuan Chujun Zhang Honggang Chen Can Zhu Sin Hang Cheung Beibei Qiu Fangfang Cai Qingya Wei Wei Liu Hang Yin Rui Zhang Jidong Zhang Ye Liu Huotian Zhang Weifang Liu Hongjian Peng Junliang Yang Lei Meng Feng Gao Shukong So Yongfang Li Yingping Zou | 2020 | Science China Chemistry2020，63，8： | 1 |
| 15 | Degradation of SARS-CoV-2 receptor ACE2 by the E3 ubiquitin ligase Skp2 in lung epithelial cells显示文摘An unexpected observation among the COVID-19 pandemic is that smokers constituted only 1.4%–18.5%of hospitalized adults,calling for an urgent investigation to determine the role of smoking in SARS-CoV-2 infection.Here,we show that cigarette smoke extract(CSE)and carcinogen benzo(a)pyrene(BaP)increase ACE2 mRNA but trigger ACE2 protein catabolism.BaP induces an aryl hydrocarbon receptor(AhR)-dependent upregulation of the ubiquitin E3 ligase Skp2 for ACE2 ubiquitination.ACE2 in lung tissues of non-smokers is higher than in smokers,consistent with the findings that tobacco carcinogens downregulate ACE2 in mice.Tobacco carcinogens inhibit SARS-CoV-2 spike protein pseudovirions infection of the cells.Given that tobacco smoke accounts for 8 million deaths including 2.1 million cancer deaths annually and Skp2 is an oncoprotein,tobacco use should not be recommended and cessation plan should be prepared for smokers in COVID-19 pandemic. | Guizhen Wang Qun Zhao Hui Zhang Fan Liang Chen Zhang Jun Wang Zhenyin Chen Ran Wu Hong Yu Beibei Sun Hua Guo Ruie Feng Kaifeng Xu Guangbiao Zhou | 2021 | Frontiers of Medicine2021，15，2： | 1 |
| 16 | High frequency of alternative splicing variants of the oncogene Focal Adhesion Kinase in neuroendocrine tumors of the pancreas and breast显示文摘The characteristic genetic abnormality of neuroendocrine neoplasms(NENs),a heterogeneous group of tumors found in various organs,remains to be identified.Here,based on the analysis of the splicing variants of an oncogene Focal Adhesion Kinase(FAK)in The Cancer Genome Atlas datasets that contain 9193 patients of 33 cancer subtypes,we found that Box 6/Box 7-containing FAK variants(FAK^(6/7))were observed in 7(87.5%)of 8 pancreatic neuroendocrine carcinomas and 20(11.76%)of 170 pancreatic ductal adenocarcinomas(PDACs).We tested FAK variants in 157 tumor samples collected from Chinese patients with pancreatic tumors,and found that FAK^(6/7)was positive in 34(75.6%)of 45 pancreatic NENs,19(47.5%)of 40 pancreatic solid pseudopapillary neoplasms,and 2(2.9%)of 69 PDACs.We further tested FAK splicing variants in breast neuroendocrine carcinoma(BrNECs),and found that FAK^(6/7)was positive in 14(93.3%)of 15 BrNECs but 0 in 23 non-NEC breast cancers.We explored the underlying mechanisms and found that a splicing factor serine/arginine repetitive matrix protein 4(SRRM4)was overexpressed in FAK^(6/7)-positive pancreatic tumors and breast tumors,which promoted the formation of FAK^(6/7)in cells.These results suggested that FAK^(6/7)could be a biomarker of NENs and represent a potential therapeutic target for these orphan diseases. | Dawei Xie Zheng Wang Beibei Sun Liwei Qu Musheng Zeng Lin Feng Mingzhou Guo Guizhen Wang Jihui Hao Guangbiao Zhou | 2023 | Frontiers of Medicine2023，17，5： | 0 |
| 17 | BGB-A445,a novel non-ligand-blocking agonistic anti-OX40 antibody,exhibits superior immune activation and antitumor effects in preclinical models显示文摘t OX40 is a costimulatory receptor that is expressed primarily on activated CD4+,CD8+,and regulatory T cells.The ligation of OX40 to its sole ligand OX40L potentiates T cell expansion,differentiation,and activation and also promotes dendritic cells to mature to enhance their cytokine production.Therefore,the use of agonistic anti-Ox40 antibodies for cancer immunotherapy has gained great interest.However,most of the agonistic anti-OX40 antibodies in the clinic are OX40L-competitive and show limited efficacy.Here,we discovered that BGB-A445,a non-ligand-competitive agonistic anti-OX40 antibody currently under clinical investigation,induced optimal T cell activation without impairing dendritic cell function.In addition,BGB-A445 dose-dependently and significantly depleted regulatory T cells in vitro and in vivo via antibody-dependent cellular cytotoxicity.In the MC38 syngeneic model established in humanized OX40 knock-in mice,BGB-A445 demonstrated robust and dose-dependent antitumor efficacy,whereas the ligand-competitive anti-Ox40 antibody showed antitumor efficacy characterized by a hook effect.Furthermore,BGB-A445 demonstrated a strong combination antitumor effect with an anti-PD-1 antibody.Taken together,our findings show that BGB-A445,which does not block OX40-OX40L interaction in contrast to clinical-stage anti-OX40 antibodies,shows superior immune-stimulating effects and antitumor efficacy and thus warrants further clinical investigation. | Beibei Jiang Tong Zhang Minjuan Deng Wei Jin Yuan Hong Xiaotong Chen Xin Chen Jing Wang Hongjia Hou Yajuan Gao Wenfeng Gong Xing Wang Haiying Li Xiaosui Zhou Yingcai Feng Bo Zhang Bin Jiang Xueping Lu Lijie Zhang Yang Li Weiwei Song Hanzi Sun Zuobai Wang Xiaomin Song Zhirong Shen Xuesong Liu Kang Li Lai Wangl Ye Liu | 2023 | Frontiers of Medicine2023，17，6： | 0 |
| 18 | Effects of different soil amendments on physicochemical property of soda saline-alkali soil and crop yield in Northeast China显示文摘Soil amendment is one of the most effective methods to improve saline-alkali soil.In this study,laboratory experiments were conducted to verify the effect of 13 kinds of amendments and their combinations(Citric acid(NM),Phosphogypsum(LS),Aluminum sulfate+citric acid(AL+NM),Aluminum sulfate+phosphogypsum(AL+LS),Aluminum sulfate+citric acid+phosphogypsum(HH),Zeolite(Z),Acidified zeolite(ZH),Aluminum sulfate(AL),Aluminum sulfate+zeolite(AL+Z),Aluminum sulfate+acidified zeolite(AL+ZH),Poly Aluminum chloride(ALCL),Polyaluminium chloride+zeolite(ALCL+Z),Polyaluminium chloride+acidified zeolite(ALCL+ZH))on soil pH,metal cations content,exchangeable Na+,exchangeable sodium percentage(ESP)in the lab.And then the five most effective amendments(Z,ZH,AL,AL+Z,and AL+ZH)were chosen applying both in dry field(maize field)and paddy field to evaluate their improvement on soda saline-alkali soil and crop yield in the northeast Songnen Plain,China.The lab results showed that AL,AL+Z and AL+ZH treatments could significantly reduce the pH in soil solution and increase the content of metal cations.Z and ZH treatments could adsorb metal cations in soil.Both in dry and paddy fields,all five treatments could increase the soil saturated hydraulic conductivity(Ks),increased from 9.63 to 60.02 mm/d and 0.18 to 33.25 mm/d,respectively,of which the AL treatment was the best;all five treatments could reduce the content of exchangeable Na+in soil,and decrease by 38.62%-61.33%and 25.24%-71.53%,respectively,of which the AL+ZH treatment was the best;all treatments could reduce soil exchangeable sodium percentage,and decrease by 0.14-0.22 and 0.14-0.41,respectively,of which the AL+ZH treatment was the best;AL,AL+Z and AL+ZH treatments could improve soil organic matter content;all treatments could effectively improve the yield of crops,and increase 23.98%-60.75%and 52.51%-260.21%,respectively,of which the AL treatment was the best in dry field and the AL+ZH treatment was the best in paddy field.The effect of AL treatment was the best in dry field and AL+ZH treatment was the best in paddy field of soda saline-alkali soil.This study could provide instructive information for the chemical improvement and agricultural utilization of soda saline-alkali soils in the world. | Fan Xiao Beibei Zhou Hongbin Wang Manli Duan Lei Feng | 2022 | International Journal of Agricultural and Biological Engineering2022，15，1： | 0 |
| 19 | Calculation of natural circulation under heaving motion显示文摘Wide validation of self-developed program of natural circulation under oceanic conditions has been conducted compared with experimental data of inclination,zero-power condition and hot-state condition.Experiments were performed on a full-scale,whole parameterization natural circulation loop designed with reference to 5 MW experimental low temperature nuclear heating reactor(NHR)of Tsinghua University.Investigation of natural circulation and parameter effect under heaving motion was carried out using the program and comparison of heaving,inclination and rolling on natural circulation respectively to reveal the influence mechanism.Results indicate that:(1)significant influence of heaving motion on natural circulation was observed,and heaving motion with high level of strength and long cycle would lead to severe flow fluctuation;(2)slight effect was caused by short cycle heaving motion which was completely different from long cycle heaving motion;(3)comprehensive action of alternating force and flow density distribution would result in natural circulation under heaving motion;(4)most severe accidents maybe result from the long cycle heaving motion rather than inclination and rolling motion.Investigation of influence of heaving motion on natural circulation could have important reference significance in the optimization design of nuclear reactors. | FENG BeiBei YANG XingTuan JIANG ShengYao | 2014 | Science China(Technological Sciences)2014，57，8： | 0 |
| 20 | Fuel type preference of taxi driver and its implications for air emissions显示文摘天然气在 2005 为出租车成为了可得到的燃料并且在南京在出租车工业占据了 43.6% 的市场份额到 2010 为止,中国。为了调查精力代替模式以及出租车工业的污染物质减小潜力,首先,为他们的下辆出租车的出租车司机的燃料偏爱决定因素被分析。作为为传统的汽油的一种重要选择,天然气广泛地被接受的结果表演(75%) 坐出租司机。与集中了于更干净的燃料代替的早阶段的以前的研究不同,有各种各样的特征的出租车司机(例如年龄,工作经验,和教育水平) 当他们选择他们的下辆出租车时,与他们的燃料偏爱一致。结果建议与特定的特征使消费者担心的政策可以在市场份额的变化上有小效果,当其他的燃料市场被开发了很好时。另外,在燃料市场的气体的增加的份额完成精力消费的 7.2% 减小。就生命周期排出物而言,下列空气污染物质,也就是温室气体( GHG ),碳的氧化物(公司),氮氧化物(没有 x ),微粒事(下午)和烃( C x H y ),获得10.0%,3.5%,20.5%,36.1%,和26.4%减小分别地。假设以有本地政策干预,精力保存和五个学生的天然气为动力的所有出租车舰队让污染物质排出物通风能相应地与 12.2% , 16.0% , 8.8% , 22.5% , 44.2% ,和 49.4% 完成最大的减小。 | Feng WANG Beibei LIU Bing ZHANG Jun BI | 2015 | Frontiers of Environmental Science & Engineering2015，9，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员