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| 1 | Gastric partitioning for the treatment of malignant gastric outlet obstruction显示文摘BACKGROUND Gastric outlet obstruction(GOO)is one of the main complications in stage IV gastric cancer patients.This condition is usually managed by gastrojejunostomy(GJ).However,gastric partitioning(GP)has been described as an alternative to overcoming possible drawbacks of GJ,such as delayed gastric emptying and tumor bleeding.AIM To compare the outcomes of patients who underwent GP and GJ for malignant GOO.METHODS We retrospectively analyzed 60 patients who underwent palliative gastric bypass for unresectable distal gastric cancer with GOO from 2009 to 2018.Baseline clinicopathological characteristics including age,nutritional status,body mass index,and performance status were evaluated.Obstructive symptoms were graded according to GOO score(GOOS).Surgical outcomes evaluated included duration of the procedure,surgical complications,mortality,and length of hospital stay.Acceptance of oral diet after the procedure,weight gain,and overall survival were the long-term outcomes evaluated.RESULTS GP was performed in 30 patients and conventional GJ in the other 30 patients.The mean follow-up was 9.2 mo.Forty-nine(81.6%)patients died during that period.All variables were similar between groups,with the exception of worse performance status in GP patients.The mean operative time was higher in the GP group(161.2 vs 85.2 min,P<0.001).There were no differences in postoperative complications and surgical mortality between groups.The median overall survival was 7 and 8.4 mo for the GP and GJ groups,respectively(P=0.610).The oral acceptance of soft solids(GOOS 2)and low residue or full diet(GOOS 3)were reached by 28(93.3%)GP patients and 22(75.9%)GJ patients(P=0.080).Multivariate analysis demonstrated that GOOS 2 and GOOS 3 were the main prognostic factors for survival(hazard ratio:8.90,95%confidence interval:3.38-23.43,P<0.001).CONCLUSION GP is a safe and effective procedure to treat GOO.Compared to GJ,it provides similar surgical outcomes with a trend to better solid diet acceptance by patients. | Marcus Fernando Kodama Pertille Ramos Leandro Cardoso Barchi Rodrigo Jose de Oliveira Marina Alessandra Pereira Donato Roberto Mucerino Ulysses Ribeiro Jr Bruno Zilberstein Ivan Cecconello | 2019 | World Journal of Gastrointestinal Oncology2019，11，12： | 2 |
| 2 | Hormetic effect(s) of tetracyclines as environmental contaminant on Zea mays显示文摘 | Luciana Migliore Feliciana Godeas Stefania Paola De Filippis Paolo Mantovi Davide Barchi Cecilia Testa Nicolino Rubattu Gianfranco Brambilla | 2009 | Environmental Pollution2009，，1： | 2 |
| 3 | Segregation distortion and linkage analysis in eggplant (Solanum melongena L ) 显示文摘 | Barchi L Lanteri S Portis E | 2010 | Genome2010，53，10： | 1 |
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| 12 | QTL analysis of plant development and fruit traits in pepper and performance of selective phenotyping显示文摘 | Lorenzo Barchi Véronique Lefebvre Anne-Marie Sage-Palloix Sergio Lanteri Alain Palloix | 2009 | Theoretical and Applied Genetics2009，，6： | 1 |
| 13 | The impact of specialized centers of care for spinal cord injury on length of stay,complications,and mortality:a systematic review of the literature显示文摘 | Parent S Barchi S Lebreton M | | 0，，： | 1 |
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| 15 | Structural evolution of a fold and thrust belt generated by multiple decollements: Analogue models and natural examples from the Northern Ape nnines (Italy)显示文摘 | Massoli D Koyi H A Barchi M R | 2006 | Journal of Structural Geology2006，28，： | 1 |
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| 17 | Mining the NCI antiviral compounds for HIV-1 integrase inhibitors显示文摘 | DENG J KELLEY JA BARCHI JJ | 2006 | Bioorg Med Chem2006，14，11： | 1 |
| 18 | QTL analysis of plant development and fruit'raits in pepper and performance of selective phenotyping显示文摘 | Barchi L Lefebvre V Sage-Palloix A M Lanteri S Palloix A | | 0，，： | 1 |
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