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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Morphology and subdivision of Amanita and a monograph of its section Lepidella显示文摘 | Bars C | 1969 | Persoonia1969，，5： | 1 |
| 3 | Pulse Transit Time and Blood Pressure Changes Following Auditory-e- voked Subcortical Arousal and Waking of Infants 显示文摘 | Barbara C Galland Evan Tan Bar J Taylor | 2007 | Sleep2007，30，7： | 1 |
| 4 | Pathology teach and tell: eosinophilic granuloma 显示文摘 | Khalil F K Wallis Crespo M C Gilbert Barness E | 2004 | Fetal Pediatr Pathol2004，23，4： | 1 |
| 5 | Manganese(Ⅲ)acetate mediated radical reactions in the presence of an ionic liquid显示文摘 | BAR G PARSONS A F THOMAS C B | 2001 | ChemCommun2001，15，： | 1 |
| 6 | Q-T dispersion and sudden unexpected death in chronic heart failure 显示文摘 | Bar C Nass A Freeman M | 1994 | Lancet1994，343，： | 1 |
| 7 | Breast cancer HER-2 equiv- ocal cases: is there an alternative to FISH testing? A pilot study u- sing two different antibodies sequentially 显示文摘 | Yosepovich A Avivi C Bar J | 2010 | lsr Med Assnc J2010，12，6： | 1 |
| 8 | ABL-specific tyrosine kinase inhibitor imatinib as salvage therapy in a child with Philadelphia chromosomepositive acute mixed lineage leukemia ( AMLL ) 显示文摘 | Selle B Bar C Hecker S | 2002 | Leukemia2002，16，7： | 1 |
| 9 | On opti- meal track- to -track fusion 显示文摘 | CHANG K C SAHA R K BAR - SHALOM Y | 1977 | IEEE Trans on AES1977，33，4： | 1 |
| 10 | Characteristic electrocardiographic pattern indicating a critical stenosis high in left anterior descending coronary artery in patients admitted because of impending myocardial infraction显示文摘 | De Zwaan C Bar FW Wellens HJ | 1982 | Am Heart J1982，103，42： | 1 |
| 11 | Usage of smart antenna for cancelling neighboring base-station interferences in wireless CDMA communicaions显示文摘 | YE W C BAR N ALEXANDER M H | 1997 | IEEE Signals Systems & Computers1997，1998，1： | 1 |
| 12 | Characterization of monascidin A from Monascus as citrinin显示文摘 | P J Blanc J P Laussac J L Bars P L Bars M O Lotet A Pareilleux D Prome J C Prome A L Santerre G Goma | 1995 | International Journal of Food Microbiology1995，27，： | 1 |
| 13 | Effect of activated protein C on pulmonary blood flow and cytokine production in experimental acute lung injury显示文摘 | Richard J C Bregeon F Leray V Le Bars D Costes N Tourvieille C | 2007 | Intensive Care Med2007，33，： | 1 |
| 14 | Association of laryngopharyngeal manifestations and gatroesophageal reflux显示文摘 | Sema Zer Toros Ahmet Burak Toros Ozlem Doganer Yüksel Leyla Ozel C?nar Akkaynak Bar?s Naiboglu | 2009 | European Archives of Oto - Rhino - Laryngology2009，，3： | 1 |
| 15 | MicroRNA profiling in pediatric pilocytic astrocytoma reveals biologically relevant targets, including PBX3, NFIB, and METAP2显示文摘 | Ho CY Bar E Giannini C | 2013 | Neuro Oncol2013，15，1： | 1 |
| 16 | Heart rate monitoring in soccer: interest and limits during competitive match play and training, practical applica- tion显示文摘 | Alexandre D da Silva C D Hill-Haas S Wong del P Natali A J De Lima J R Bars Filho M G Matins J J Garcia E S Karim C | 2012 | J Strength C ond Res2012，26，10： | 1 |
| 17 | Microalbuminuria after pregnancy complicated by pre-eclampsia显示文摘 | Bar J Kaplan B Wittenberg C | 1999 | Nephrol Dial Transplant1999，14，5： | 1 |
| 18 | Characterization of monascidin A from Monascus as citrinin显示文摘 | Blanc P C Laussac J P Bars J L | 1995 | International Journal of Food Microbiology1995，，23： | 1 |
| 19 | Colony-stimulating factors: clinical evidence for treatment and prophylaxis of chemotherapy-induced febrile neutropenia显示文摘 | César Gómez Raposo álvaro Pinto Marín Manuel González Barón | 2006 | Clinical and Translational Oncology2006，，10： | 1 |
| 20 | Characteristic elec- trocardiographic pattern indicating a critical stenosis high in left anterior descending coronary artery in patients ad- mitted because of impending myocardial infarction 显示文摘 | de Zwaan C Bar F W Wellens H J | 1982 | Am Heart J1982，103，42： | 1 |
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