|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 亚太地区胃食管反流病的处理共识:更新版显示文摘背景与目的:自从2004年亚太地区胃食管反流病(GERD)共识发表以来,更多关于GERD流行病学和处理的文献资料相继出现。有必要对这些资料进行循证综述,对共识作出更新。方法:由多学科专家组应用德尔菲(Delphi)法制定共识条文,提呈相关资料,并对证据质量、推荐力度和共识水平进行分级。结果:亚洲GERD发生率日益增加。其危险因素包括老年、男性、种族、家族史、社会经济地位高、体重指数增加和吸烟。对于有典型症状而无报警症状的患者,对质子泵抑制剂(PPI)试验有症状应答具有诊断意义。如PPI试验失败,停止治疗后pH监测结果阴性可排除GERD。窄带成像、胶囊内镜检查和无线pH监测的作用尚未明确。亚洲诊断策略的制定须考虑到并存的胃癌和消化性溃疡。减轻体质量和抬高床头可改善反流症状。PPIs是最有效的内科治疗手段。对于非糜烂性反流病(NERD)患者,按需治疗较为适宜。有慢性咳嗽、喉炎和典型GERD症状的患者在排除非GERD病因后,应予PPI每天两次治疗。如有经验丰富的外科医师,GERD患者可行胃底折叠术。除临床试验外,GERD不应采用内镜治疗。结论:新的诊断方法和内镜治疗的作用有待进一步研究阐明。亚洲GERD诊断策略的制定须考虑到并存的胃癌和消化性溃疡。PPIs仍为治疗的基石。 | Kwong Ming Fock Nicholas J Talley Ronnie Fass Khean Lee Goh Peter Katelaris Richard Hunt Michio Hongo Tiing Leong Ang Gerald Holtmann Sanjay Nandurkar San Ren Lin Benjamin CY Wong Francis KL Chan Abdul Aziz Rani Young-Tae Bak Jose Sollano Khek Yu Ho Sathoporn Manatsathit 钱本余 | 2008 | 胃肠病学2008，13，7： | 21 |
| 2 | Prevention and management of hepatitis B virus reactivation in patients with hematological malignancies treated with anticancer therapy显示文摘Hepatitis due to hepatitis B virus(HBV) reactivation can be severe and potentially fatal, but is preventable. HBV reactivation is most commonly reported in patients receiving cancer chemotherapy, especially rituximabcontaining therapy for hematological malignancies and those receiving stem cell transplantation. All patients with hematological malignancies receiving anticancer therapy should be screened for active or resolved HBV infection by blood tests for hepatitis B surface antigen(HBs Ag) and antibody to hepatitis B core antigen(antiHBc). Patients found to be positive for HBs Ag should be given prophylactic antiviral therapy to prevent HBV reactivation. For patients with resolved HBV infection, no standard strategy has yet been established to prevent HBV reactivation. There are usually two options. One is pre-emptive therapy guided by serial HBV DNA monitoring, whereby antiviral therapy is given as soon as HBV DNA becomes detectable. However, there is little evidence regarding the optimal interval and period of monitoring. An alternative approach is prophylactic antiviral therapy, especially for patients receiving highrisk therapy such as rituximab, newer generation of anti-CD20 monoclonal antibody, obinutuzumab or hematopoietic stem cell transplantation. This strategy may effectively prevent HBV reactivation and avoid the inconvenience of repeated HBV DNA monitoring. Entecavir or tenofovir are preferred over lamivudine as prophylactic therapy. Although there is no well-defined guideline on the optimal duration of prophylactic therapy, there is growing evidence to recommend continuing prophylactic antiviral therapy for at least 12 mo after cessation of chemotherapy, and even longer for those who receive rituximab or who had high serum HBV DNA levels before the start of immunosuppressive therapy. Many novel agents have recently become available for the treatment of hematological malignancies, and these agents may be associated with HBV reactivation. Although there is currently limited evidence to guide the optimal preventive measures, we recommend antiviral prophylaxis in HBs Ag-positive patients receiving novel treatments, especially the Bruton tyrosine kinase inhibitors and the phosphatidylinositol 3-kinase inhibitors, which are B-cell receptor signaling modulators and reduce proliferation of malignant B-cells. Further studies are needed to clarify the risk of HBV reactivation with these agents and the best prophylactic strategy in the era of targeted therapy for hematological malignancies. | Man Fai Law Rita Ho Carmen KM Cheung Lydia HP Tam Karen Ma Kent CY So Bonaventure Ip Jacqueline So Jennifer Lai Joyce Ng Tommy HC Tam | 2016 | World Journal of Gastroenterology2016，22，28： | 10 |
| 3 | Asymmetric membrane capsules for delivery of poorly water-soluble drugs by osmotic effects 显示文摘 | Wang CY Ho HO Lin LH | 2005 | IntJPharm2005，297，12： | 1 |
| 4 | Cucurb-itacin B induces apoptosis and S phase cell cycle arrest in BEL-7402human hepatocellular carcinoma cells and is effective via oral admin-istration显示文摘 | Chan KT Meng FY Li Q Ho CY Lam TS To Y | 2010 | Cancer Lett2010，294，1： | 1 |
| 5 | Immunoidentification of gonadotropin releasing hormone receptor in human sperm, pituitary and cancer cells显示文摘 | Lee CY Ho J Chow SN | 2000 | Am J Reprod Immunol2000，44，3： | 1 |
| 6 | Elevated production of interleukin-18 is associated with renal disease in patients with systemic lupus erythematosus显示文摘 | Wong CK Ho CY Li EK | 2002 | Clin Exp Immunol2002，130，2： | 1 |
| 7 | Elevation of proinflammatory cytokine (IL-18, IL-17, IL-12) and Th2 eytokine (IL-4) concentrations in patients with systemic lupus erythematous 显示文摘 | Wong CK Ho CY Li EK | 2000 | Lupus2000，9，： | 1 |
| 8 | Elevated plasma concentrations of nitric oxide, soluble thrombomodul in and soluble vascular cell adhesion molecule- 1 in patients with systemic lupus erythematosus显示文摘 | Ho CY Wong CK Li EK | 2003 | Rheumatology (Oxford)2003，42，1： | 1 |
| 9 | Cytotoxic activities of Coriolusversicolor (Yunzhi)extract on human leukemia and lym-phoma cells by in duction of apoptosis显示文摘 | Lau CB Ho CY Kim CF | 2004 | Life Sci2004，75，7： | 1 |
| 10 | Endotoxemia contributes to the immune paralysis in patients with cirrhosis显示文摘 | Lin CY Tsai IF Ho YP | 2007 | J Hepatol2007，46，5： | 1 |
| 11 | 显示文摘 | Ho CY Wong CK Li EK | 2001 | Immunol Invest2001，30，3： | 1 |
| 12 | Cutaneous metastases of osteosarcoma on the scalp显示文摘 | Ho CY Yang KC Chang WH | 2006 | Dermatol Sinica2006，24，： | 1 |
| 13 | Cephalometric analysis of nonobese snorers either with or without obstructive sleep apnea syndrome 显示文摘 | Tsai HH Ho CY Lee PL | 2007 | Angle Orthodontist2007，77，6： | 1 |
| 14 | Validity of the keratometric index: evaluation by the Pentacam rotating Scheimpflug camera 显示文摘 | HO JD TSAI CY TSAI ILl | 2008 | J Cataract Refract Surg2008，34，1： | 1 |
| 15 | Pathology of the motor sensory axonal Guillain-Barre syndrome显示文摘 | Griffin JW Li CY Ho TW | 1996 | Ann Neurol1996，39，： | 1 |
| 16 | Early recognition of nasopharyngeal cancer in adults with only otitis media with effusion显示文摘 | Ho KY Lee KW Chai CY | 2008 | J Otolaryngol Head Neck Surg2008，37，3： | 1 |
| 17 | TREM-1 expression in Tumor- associated macrophages and clinical outcome in lung cancer 显示文摘 | Ho CC Liao WY Wang CY | 2008 | Am J Respir Crit Care Med2008，177，： | 1 |
| 18 | Accuracy of CT cerebral perfusion in predicting infarct in the emergency department : lesion characterization on CT perfusion based on commercially available software 显示文摘 | Ho CY YIussain S Alan T | 2013 | Emerg Radiol2013，20，3： | 1 |
| 19 | Links ribotyping of vibrio parahaemolyticus isolates obtained from food poisoning outbreaks in Taiwan显示文摘 | Ho CY Kuo LP | 1999 | Microbiol Immunol1999，43，7： | 1 |
| 20 | Guillain-Barré syndrome in northern China:Relationship to Campylobacter jejuni infection and anti-glycolipid antibodies显示文摘 | Mishu B Li CY | 1995 | Brain1995，118，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员