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| 1 | TGF-β/BMP signaling and other molecular events: regulation of osteoblastogenesis and bone formation显示文摘Transforming growth factor-beta(TGF-β)/bone morphogenetic protein(BMP) plays a fundamental role in the regulation of bone organogenesis through the activation of receptor serine/threonine kinases. Perturbations of TGF-β/BMP activity are almost invariably linked to a wide variety of clinical outcomes, i.e., skeletal, extra skeletal anomalies, autoimmune, cancer, and cardiovascular diseases. Phosphorylation of TGF-β(I/II) or BMP receptors activates intracellular downstream Smads, the transducer of TGF-β/BMP signals. This signaling is modulated by various factors and pathways, including transcription factor Runx2. The signaling network in skeletal development and bone formation is overwhelmingly complex and highly time and space specific.Additive, positive, negative, or synergistic effects are observed when TGF-β/BMP interacts with the pathways of MAPK, Wnt, Hedgehog(Hh), Notch, Akt/m TOR, and mi RNA to regulate the effects of BMP-induced signaling in bone dynamics. Accumulating evidence indicates that Runx2 is the key integrator, whereas Hh is a possible modulator, mi RNAs are regulators, and b-catenin is a mediator/regulator within the extensive intracellular network. This review focuses on the activation of BMP signaling and interaction with other regulatory components and pathways highlighting the molecular mechanisms regarding TGF-β/BMP function and regulation that could allow understanding the complexity of bone tissue dynamics. | Md Shaifur Rahman Naznin Akhtar Hossen Mohammad Jamil Rajat Suvra Banik Sikder M Asaduzzaman | 2015 | Bone Research2015，3，1： | 53 |
| 2 | nsights into molecular therapy of glioma: current .-hallenges and next generation blueprint显示文摘Glioma 说明人的大脑肿瘤的多数。与占优势的治疗政体,病人有差的幸存率。尽管有在主流的 glioma 治疗的当前的开发,为 glioma 的痊愈看起来从活动范围。glioma 和获得的电阻的渗透性的性质 substancially 限制治疗学的选择。glioma 和 proteogenomic 描述的复杂 pathobiology 的更好的说明可能最后为更复杂、有效的联合政体的设计打开新奇大街。这能被个别地定制进步 neuroimaging 技术完成,终止有 激活prodrug 基因的 DNA 合成, silencing gliomagenesis 基因(基因治疗),指向的 miRNA oncogenic 活动( miRNA-mRNA 相互作用),有干细胞治疗的联合 Hedgehog-Gli/Akt 禁止者,作为抗原采用肿瘤 lysates 由细胞毒素的 T 淋巴细胞(树枝状的房间种痘)为肿瘤特定的癌症干细胞的有效弄空采购原料,妄想的反的采纳转移因此,现在的评论捕获与分子的机制象外科,放射和化疗的限制一样在 glial tumorigenesis 包含了联系的最近的趋势。在这篇文章,我们极其也讨论下一代为 glioma 的成功的治疗的分子的治疗学的策略和他们的机制。 | Y RAJESH Ipsita PAL Payel BANIK Sandipan CHAKRABORTY Sachin A BORKAR Goutam DEY Ahona MUKHERJEE Mahitosh MANDAL | 2017 | Acta Pharmacologica Sinica2017，38，5： | 16 |
| 3 | Effect of Processing and Composition on the Structure and Properties of P/M EP741NP Type Alloys显示文摘A study was carried out on the effects of processing and composition on the structure and properties of P/M EP741NP type alloys. The objectives of this study were to understand the role of Hf in a P/M superalloy containing high niobium used in aircraft engines and to determine the effects of extrusion and forging the powders as contrasted to HIPing (hot isostatic pressing) only. Two alloys of the P/M EP741NP composition were atomized: one alloy contained 0.26%Hf and the other was Hf free. After the as-atomized powders from both alloys were characterized, the powders were extruded into billets, forged and heat treated. After each process, the microstructures were characterized by SEM and the phases were extracted and identified by X-ray diffraction. The presence of Hf in the residues was probed by EDS (energy dispersive spectroscopy). The alloys were given the published Russian heat treatment as well as a more conventional heat treatment more typical of western powder alloys. Tensile, creep and stress rupture mechanical property tests were run. Results of the structural behavior of the alloys after each processing step will be presented and discussed. The role of the Hf on the mechanical proper- ties will be discussed. | John Radavich Tadeu Carneiro David Furrer Joseph Lemsky Anthony Banik | 2007 | Chinese Journal of Aeronautics2007，20，2： | 7 |
| 4 | Risk factors for severity and mortality in patients with MERS-CoV:Analysis of publicly available data from Saudi Arabia显示文摘Dear Editor,Middle East respiratory syndrome coronavirus(MERS-CoV)has affected over 1600 people across four continents;it has a fatality rate of about 36%(WHO,2015).Approximately 75%of MERS-CoV patients have a preexisting medical condition(Zumla et al.,2015).MERS-CoV is especially severe in patients with comorbidities. | Gouri Rani Banik Amani Salem Alqahtani Robert Booy Harunor Rashid | 2016 | Virologica Sinica2016，31，1： | 6 |
| 5 | Multi-criteria land evaluation for suitability analysis of wheat:a case study of a watershed in eastern plateau region,India显示文摘Improper land use results in land degradation as well as decline in agricultural productivity.To obtain optimum benefit from the land,proper utilization of its resources is necessary.Land suitability analysis is the evaluation and grouping of specific areas of land in terms of their suitability for a defined use,which is a precondition for sustainable land use planning.This study investigated the applicability of Geographical Information System(GIS)techniques in combination with multi-criteria land evaluation for analysing land suitability.The study used the weighted overlay technique for multi-criteria evaluation with GIS for the assessment of suitability of wheat cultivation in Beko watershed(Purulia,India).The watershed area is moderately suitable for wheat crop production,with constraints like imperfect drainage and poor soil depth. | Aditi SARKAR Amit GHOSH Pabitra BANIK | 2014 | Geo-Spatial Information Science2014，17，2： | 3 |
| 6 | Phytochemical and in vitro biological investigations of methanolic extracts of Enhydra fluctuans Lour显示文摘Objective:To study the phytochemical and biological properties(antioxidant,anthelmintic and thrombolytic)of methanolic extracts of Enhydra fluctuant Lour.,a plant belonging to the Asteraceae family.Methods:The phytochemical evaluation was carried out by qualitative analysis.In vitro antioxidant activity of extract was studied using free radical scavenging assay,ability of reduction,total phenol and total flavonoid contents determination assays.The anthelmintic activity was determined using paralysis and death time of Pheretima posthuma(earthworm)and thrombolytic activity by clot disruption assay.Results:The phytochemical evaluation showed significant presence of flavonoids,triterpenes,carbohydrate,reducing sugars,saponins,phenols,diterpenes,protein and tannin.The antioxidant activity was found significant[IC_(50)(135.20±036)μg/mL]as compared to ascorbic acid[(130.00±0.76)μg/mL].The reducing power was increased with concentration.Total phenol and total flavonoid contents were(153.08±0.38)mg/mL and(172.04±0.56)mg/mL respectively.The paralysis and death time of earthworms for different concentrations of extract were determined and compared with albendazole.The results showed that 10 mg/mL of the crude extract had similar effect with albendazole.Additionally,the crude extract showed a concentration depended relationship with its anthelmintic property.The clot lysis activity of crude extract was compared to the standard streptokinase's clot lysis(40.13%)activity and found significant(31%).Conclusions:The study proves that the crude methanolic extract of Enhydra fluctuant Lour,has significant antioxidant,anthelmintic and thrombolytic activity containing wide range of phytochemicals. | Sourov Kuri Mustahsan Billah S.M.Masud Rana Zannatul Naim Mahmodul Islam Hasanuzzaman Ramjan Ali Rana Banik | 2014 | Asian Pacific Journal of Tropical Biomedicine2014，4，4： | 2 |
| 7 | 简易转速测量系统设计显示文摘介绍了一种基于定时器的转速测量系统的设计与开发。使用直流电动机的转轴来测量其转速,定时器IC 555用于不稳定模式。使用数字存储示波器(DSO)测量的定时器输出波形的频率几乎与转轴的转速成线性比例,而这个转速又与外部输入电压水平的变化成线性关系,由此得到了定时器输出波形频率与转速之间的线性关系。该系统的主要优点是线性输入-输出,体积小,便于携带且成本低。 | Akash Kumar Anindya Debnath Antar Banik Kabirul Islam Mondal Partha Pratim Biswas Rik Bhattacharyya T K Maiti | 2020 | Journal of Measurement Science and Instrumentation2020，11，2： | 2 |
| 8 | On the GI/M/1/N queue with working vacations-analytic analysis and computation显示文摘 | Banik A D Gupta U C Pathak S S | 2007 | Applied Mathematics Modeling2007，，： | 1 |
| 9 | Effect of supplementation of rice straw with biogas residual slurry manure on the yield, protein and mineral contents of oyster mushroom显示文摘 | Banik S Nandi R | 2004 | Industrial Crops and Products2004，20，3： | 1 |
| 10 | Bioeffects of microwave-a brief review显示文摘 | Banik S Bandyopadhyay S Ganguly S | 2003 | Bioresource Technoiogy2003，87，： | 1 |
| 11 | Molecular mechanisms in the pathogenesis of traumatic brain injury 显示文摘 | Ray SK Dixon CE Banik NL | 2002 | Histol Histopathol2002，17，4： | 1 |
| 12 | Knockdown of hTERT and concurrent treatment with interferon-gamma inhibited proliferation and invasion of human glioblastoma cell lines 显示文摘 | George J Banik N L Ray S K | 2010 | Int J Biochem Cell Biol2010，42，7： | 1 |
| 13 | Managing realtime database transactions in mobile ad-hoc networks显示文摘 | Le Gruenwald Shankar M Banik Chuo N Lau | 2007 | Distributed and Parallel Database2007，22，1： | 1 |
| 14 | Effect of pre-and postharvest treatments with calcium compounds on the incidence of postharvest fruit rots of mango显示文摘 | Kaiser S A K M Dhua R S Banik A K | 2001 | Journal of Mycopathological Research2001，39，： | 1 |
| 15 | Nanoclay modified water-blown polyurethane foams derived from bifunctional soybean oil-based polyol显示文摘 | BANIK I SAIN M M | 2010 | Polymer-Plastics Technology and Engineering2010，49，7： | 1 |
| 16 | Fine needle aspiration cytology in sclerosing stromal tumor of the ovary: a series of three cases显示文摘 | Banik T Gupta N Dey P et al | 2012 | Diagn Cytopathol2012，40，4： | 1 |
| 17 | Available phosphate content of an alluvialsoil as influenced by inoculation of some isolated phosphate-solu-bilizing microorganisms显示文摘 | BANIK S DEY B K | 1982 | Plant and Soil1982，69，3： | 1 |
| 18 | Reexamination of the difference in susceptibility to adjuvant-induced arthritis among LEW/Crj, Sic/Wistar/ST and Sic/SD rats显示文摘 | Banik R K Kasai M Mizumura K | 2002 | Exp Anita2002，51，2： | 1 |
| 19 | Opti- mization of nutrients for gellan gum production by Sphin- gomonas paucimobilis ATCC 31461 in molasses based medium using response surface methodology 显示文摘 | BANIK R M SANTHIAGU A UPADHYAY S N | 2007 | Biore- sour Technol2007，98，4： | 1 |
| 20 | Calpain in the pathophysiology of spinal cord injury:neuroprotection with calpain inhibitors显示文摘 | Ray SK Hogan EL Banik NL | | 0，，： | 1 |
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