1篇
您的检索式：作者名="Mahmodul Islam"
|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Phytochemical and in vitro biological investigations of methanolic extracts of Enhydra fluctuans Lour显示文摘Objective:To study the phytochemical and biological properties(antioxidant,anthelmintic and thrombolytic)of methanolic extracts of Enhydra fluctuant Lour.,a plant belonging to the Asteraceae family.Methods:The phytochemical evaluation was carried out by qualitative analysis.In vitro antioxidant activity of extract was studied using free radical scavenging assay,ability of reduction,total phenol and total flavonoid contents determination assays.The anthelmintic activity was determined using paralysis and death time of Pheretima posthuma(earthworm)and thrombolytic activity by clot disruption assay.Results:The phytochemical evaluation showed significant presence of flavonoids,triterpenes,carbohydrate,reducing sugars,saponins,phenols,diterpenes,protein and tannin.The antioxidant activity was found significant[IC_(50)(135.20±036)μg/mL]as compared to ascorbic acid[(130.00±0.76)μg/mL].The reducing power was increased with concentration.Total phenol and total flavonoid contents were(153.08±0.38)mg/mL and(172.04±0.56)mg/mL respectively.The paralysis and death time of earthworms for different concentrations of extract were determined and compared with albendazole.The results showed that 10 mg/mL of the crude extract had similar effect with albendazole.Additionally,the crude extract showed a concentration depended relationship with its anthelmintic property.The clot lysis activity of crude extract was compared to the standard streptokinase's clot lysis(40.13%)activity and found significant(31%).Conclusions:The study proves that the crude methanolic extract of Enhydra fluctuant Lour,has significant antioxidant,anthelmintic and thrombolytic activity containing wide range of phytochemicals. | Sourov Kuri Mustahsan Billah S.M.Masud Rana Zannatul Naim Mahmodul Islam Hasanuzzaman Ramjan Ali Rana Banik | 2014 | Asian Pacific Journal of Tropical Biomedicine2014，4，4： | 2 |
您所在的机构暂未开通此部分的功能，请联系管理员