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| 1 | A systematic review of the efficacy and safety of herbal medicines used in the treatment of obesity显示文摘This review focuses on the efficacy and safety of effective herbal medicines in the management of obesity in humans and animals. PubMed, Scopus, Google Scholar, Web of Science, and IranMedex databases were searched up to December 30, 2008. The search terms were 'obesity' and ('herbal medicine' or 'plant', 'plant medicinal' or 'medicine traditional') without narrowing or limiting search elements. All of the human and animal studies on the effects of herbs with the key outcome of change in anthropometric measures such as body weight and waist-hip circumference, body fat, amount of food intake, and appetite were included. In vitro studies, reviews, and letters to editors were excluded. Of the publications identified in the initial database, 915 results were identified and reviewed, and a total of 77 studies were included (19 human and 58 animal studies). Studies with Cissus quadrangularis (CQ), Sambucus nigra , Asparagus officinalis , Garcinia atroviridis , ephedra and caffeine, Slimax (extract of several plants including Zingiber officinale and Bofutsushosan) showed a significant decrease in body weight. In 41 animal studies, significant weight loss or inhibition of weight gain was found. No significant adverse effects or mortality were observed except in studies with supplements containing ephedra,caffeine and Bofutsushosan. In conclusion, compounds containing ephedra, CQ, ginseng, bitter melon, and zingiber were found to be effective in the management of obesity. Attention to these natural compounds would open a new approach for novel therapeutic and more effective agents. | Shirin Hasani-Ranjbar Neda Nayebi Bagher Larijani Mohammad Abdollahi | 2009 | World Journal of Gastroenterology2009，15，25： | 14 |
| 2 | Modification in Media Composition to Obtain Secretory Production of STxB-based Vaccines using Escherichia coli显示文摘Shiga toxin B-subunit (STxB) from Shigella dysenteriae targets in vivo antigen to cancer cells, dendritic cells (DC) and B cells, which preferentially express the globotriaosylceramide (Gb3) receptor. This pivotal role has encouraged scientists to investigate fusing STxB with other clinical antigens. Due to the challenges of obtaining a functional soluble form of the recombinant STxB, such as formation of inclusion bodies during protein expression, scientists tend to combine STxB with vaccine candidates rather than using their genetically fused forms. In this work, we fused HPV16 E7 as a vaccine candidate to the recombinantly-produced STxB. To minimize the formation of inclusion bodies, we investigated a number of conditions during the expression procedure. Then various strategies were used in order to obtain high yield of soluble recombinant protein from E. coli which included the use of different host strains, reduction of cultivation temperature, as well as using different concentrations of IPTG and different additives (Glycin, Triton X-100, ZnCl2). Our study demonstrated the importance of optimizing incubation parameters for recombinant protein expression in E. coli; also showed that the secretion production can be achieved over the course of a few hours when using additives such as glycine and Triton X-100. Interestingly, it was shown that when the culture mediums were supplemented by additives, there was an inverse ratio between time of induction (TOI) and the level of secreted protein at lower temperatures. This study determines the optimal conditions for high yield soluble E7-STxB expression and subsequently facilitates reaching a functionally soluble form of STxB-based vaccines, which can be considered as a potent vaccine candidate for cervical cancer. | Mohammad Sadraeian Mohammad Bagher Ghoshoon Milad Mohkam Zeinab Karimi SaraRasoul-Amini Younes Ghasemi | 2013 | Virologica Sinica2013，28，1： | 7 |
| 3 | Corrosion behavior of electron beam processed AZ91 magnesium alloy显示文摘The increasing use of light alloys owing to their high performance makes magnesium alloys very attractive for the use in automotive and biomedical applications.However,it is well known that magnesium and its alloys have poor corrosion resistance in different atmospheric and aqueous environments.As a means of improving corrosion resistance through the microstructure modification,electron beam processing(EBP)was applied on the as-cast AZ91 magnesium alloy.To evaluate the microstructure influence on the corrosion-resistant,the EB processed samples underwent a solution heat treatment and an artificial aging heat treatment.Four different obtained microstructures were investigated by standard microscopy and electrochemical corrosion tests to evaluate the microstructure and its effects on the corrosion resistance of AZ91 alloy.The EBPed specimens show a significant microstructure refinement and homogenous distribution ofβ-phase at the grain boundaries surrounded by supersaturatedα-Mg which acts as a barrier against corrosion.The electrochemical corrosion test of the samples immersed in 3.5 wt%NaCl after 4 weeks indicates that the EBP improves the corrosion resistance of the alloy due to the nobler corrosion potential of supersaturated a-Mg and more stable protective hydroxide films compared to the heat-treated and as-cast conditions. | Fatemeh Iranshahi Mohammad Bagher Nasiri Fernando Gustavo Warchomicka Christof Sommitsch | 2020 | Journal of Magnesium and Alloys2020，8，4： | 7 |
| 4 | 25-gauge transconjunctival diagnostic vitrectomy in suspected cases of intraocular lymphoma: a case series and review of the literature显示文摘AIM:To report the cytology results of 25-gauge transconjunctival(25G-TSV)diagnostic vitrectomy in cases suspicious for intraocular lymphoma(IOL),and compare the results to those reported in the literature.METHODS:Clinical and cytopathological records of 18vitreous biopsy specimens obtained via 25G-TSV diagnostic vitrectomy in 12 patients suspicious for IOL were reviewed retrospectively.A review of the literature in regards to the diagnostic yields of vitreous specimens obtained via 25-gauge and 20-gauge diagnostic vitrectomy in suspected cases of IOL was performed.RESULTS:Eighteen eyes from 12 patients with clinical suspicion of IOL underwent diagnostic 25G-TSV.The cytopathological investigations demonstrated IOL in 15eyes(83.3%).Vitreous analysis was non-diagnostic in 3eyes(16.7%).CONCLUSION:Twenty-five-gauge diagnostic vitrectomy yields adequate sample for cytological evaluation of the vitreous in cases suspicious for IOL.The diagnostic results of the 25G-TSV in the current study are superior to those reported for 20-gauge vitrectomy but equivalent to those reported for 25G-TSV in the published literature. | Mozhgan Rezaei Kanavi Masoud Soheilian Sayed Bagher Hosseini Amir A. Azari | 2014 | International Journal of Ophthalmology(English edition)2014，7，3： | 7 |
| 5 | Radiation-induced inflammation and autoimmune diseases显示文摘Currently,ionizing radiation(IR)plays a key role in the agricultural and medical industry,while accidental exposure resulting from leakage of radioactive sources or radiological terrorism is a serious concern.Exposure to IR has various detrimental effects on normal tissues.Although an increased risk of carcinogenesis is the best-known long-term consequence of IR,evidence has shown that other diseases,particularly diseases related to inflammation,are common disorders among irradiated people.Autoimmune disorders are among the various types of immune diseases that have been investigated among exposed people.Thyroid diseases and diabetes are two autoimmune diseases potentially induced by IR.However,the precise mechanisms of IR-induced thyroid diseases and diabetes remain to be elucidated,and several studies have shown that chronic increased levels of inflammatory cytokines after exposure play a pivotal role.Thus,cytokines,including interleukin-1(IL-1),tumor necrosis factor(TNF-α)and interferon gamma(IFN-α),play a key role in chronic oxidative damage following exposure to IR.Additionally,these cytokines change the secretion of insulin and thyroid-stimulating hormone(TSH).It is likely that the management of inflammation and oxidative damage is one of the best strategies for the amelioration of these diseases after a radiological or nuclear disaster.In the present study,we reviewed the evidence of radiation-induced diabetes and thyroid diseases,as well as the potential roles of inflammatory responses.In addition,we proposed that the mitigation of inflammatory and oxidative damage markers after exposure to IR may reduce the incidence of these diseases among individuals exposed to radiation. | Rasoul Yahyapour Peyman Amini Saeed Rezapour Mohsen Cheki Abolhasan Rezaeyan Bagher Farhood Dheyauldeen Shabeeb Ahmed Eleojo Musa Hengameh Fallah Masoud Najafi | 2018 | Military Medical Research2018，5，1： | 7 |
| 6 | Rat hair follicle stem cells differentiate and promote recovery following spinal cord injury显示文摘Emerging studies of treating spinal cord injury(SCI)with adult stem cells led us to evaluate the effects of transplantation of hair follicle stem cells in rats with a compression-induced spinal cord lesion.Here,we proposed a hypothesis that rat hair follicle stem cell transplantation can promote the recovery of injured spinal cord.Compression-induced spinal cord injury was induced in Wistar rats in this study.The bulge area of the rat vibrissa follicles was isolated,cultivated and characterized with nestin as a stem cell marker.5-Bromo-2′-deoxyuridine(BrdU)labeled bulge stem cells were transplanted into rats with spinal cord injury.Immunohistochemical staining results showed that some of the grafted cells could survive and differentiate into oligodendrocytes(receptor-interacting protein positive cells)and neuronal-like cells(βIII-tubulin positive cells)at 3 weeks after transplantation.In addition,recovery of hind limb locomotor function in spinal cord injury rats at 8 weeks following cell transplantation was assessed using the Basso,Beattie and Bresnahan(BBB)locomotor rating scale.The results demonstrate that the grafted hair follicle stem cells can survive for a long time period in vivo and differentiate into neuronal-and glial-like cells.These results suggest that hair follicle stem cells can promote the recovery of spinal cord injury. | Nowruz Najafzadeh Maliheh Nobakht Bagher Pourheydar Mohammad Ghasem Golmohammadi | 2013 | Neural Regeneration Research2013，8，36： | 6 |
| 7 | Ultrabroad Microwave Absorption Ability and Infrared Stealth Property of Nano-Micro CuS@rGO Lightweight Aerogels显示文摘Developing ultrabroad radar-infrared compatible stealth materials has turned into a research hotspot,which is still a problem to be solved.Herein,the copper sulfide wrapped by reduced graphene oxide to obtain three-dimensional(3D)porous network composite aerogels(CuS@rGO)were synthesized via thermal reduction ways(hydrothermal,ascorbic acid reduction)and freeze-drying strategy.It was discovered that the phase components(rGO and CuS phases)and micro/nano structure(microporous and nanosheet)were well-modified by modulating the additive amounts of CuS and changing the reduction ways,which resulted in the variation of the pore structure,defects,complex permittivity,microwave absorption,radar cross section(RCS)reduction value and infrared(IR)emissivity.Notably,the obtained CuS@rGO aerogels with a single dielectric loss type can achieve an ultrabroad bandwidth of 8.44 GHz at 2.8 mm with the low filler content of 6 wt%by a hydrothermal method.Besides,the composite aerogel via the ascorbic acid reduction realizes the minimum reflection loss(RL_(min))of−60.3 dB with the lower filler content of 2 wt%.The RCS reduction value can reach 53.3 dB m^(2),which effectively reduces the probability of the target being detected by the radar detector.Furthermore,the laminated porous architecture and multicomponent endowed composite aerogels with thermal insulation and IR stealth versatility.Thus,this work offers a facile method to design and develop porous rGO-based composite aerogel absorbers with radar-IR compatible stealth. | Yue Wu Yue Zhao Ming Zhou Shujuan Tan Reza Peymanfar Bagher Aslibeiki Guangbin Ji | 2022 | Nano-Micro Letters2022，14，11： | 6 |
| 8 | Higher order aberration comparison between two aspherical intraocular lenses: MC6125AS and Akreos advanced optics显示文摘AIM: To compare higher order aberrations in two aspherical intraocular lenses(IOLs): Akreos advanced optics(AO) and Dr. Schmidt Microcrystalline 6125 aspheric anterior surface(MC6125AS) with each other. METHODS: Forty eyes of 39 patients underwent phacoemulsification and Akreos AO and MC6125 AS were implanted in their eyes in a random manner. Three months post-operatively, higher order aberrations including spherical aberration, coma aberration, and total aberrations were measured and compared.RESULTS: The total aberration was 0.24±0.17 in eyes with Dr. Schmidt and 0.20 ±0.01 in eyes with Akreos AO(P =0.361). The mean of coma aberration was 0.17 ±0.21 and 0.09 ±0.86 in Dr. Schmidt and Akreos lenses,respectively(P =0.825). Total spherical aberration was almost the same in both groups(mean: 0.05, P =0.933).Best corrected visual acuity in Akreos AO(0.10±0.68) and Dr. Schmidt(0.09±0.67) did not differ significantly(P =0.700). CONCLUSION: There is no statistically significant difference in the higher order aberrations between these two aspherical lenses. | Mohammad Taher Rajabi Sara Korouji Mahgol Farjadnia Mohammad Naderan Mohammad Bagher Rajabi Bahram Khosravi Seyed Mehdi Tabatabaie | 2015 | International Journal of Ophthalmology(English edition)2015，8，3： | 5 |
| 9 | Enhanced removal of nitrate and phosphate from wastewater by Chlorella vulgaris: Multi-objective optimization and CFD simulation显示文摘To enhance the efficiency of wastewater biotreatment with microalgae, the effects of physical parameters need to be investigated and optimized. In this regard, the individual and interactive effects of temperature, p H and aeration rate on the performance of biological removal of nitrate and phosphate by Chlorella vulgaris were studied by response surface methodology(RSM). Furthermore, a multi-objective optimization technique was applied to the response equations to simultaneously find optimal combinations of input parameters capable of removing the highest possible amount of nitrate and phosphate. The optimal calculated values were temperature of 26.3 °C, pH of 8 and aeration rate of 4.7 L·min^(-1). Interestingly, under the optimum condition, approximately 85% of total nitrate and 77% of whole phosphate were removed after 48 h and 24 h, respectively, which were in excellent agreement with the predicted values. Finally, the effect of baffle on mixing performance and, as a result, on bioremoval efficiency was investigated in Stirred Tank Photobioreactor(STP) by means of Computational Fluid Dynamics(CFD). Flow behavior indicated substantial enhancement in mixing performance when the baffle was inserted into the tank. Obtained simulation results were validated experimentally. Under the optimum condition, due to proper mixing in baffled STP, nitrate and phosphate removal increased up to 93% and 86%,respectively, compared to unbaffled one. | Mohammad Bagher Sabeti Mohammad Amin Hejazi Afzal Karimi | 2019 | Chinese Journal of Chemical Engineering2019，27，3： | 4 |
| 10 | Life Cycle Assessment modeling of milk production in Iran显示文摘Livestock units are known as one of the most influential sectors in the environment pollution.Therefore,the aim of this study was to investigate the environmental impacts of milk production in Guilan province of Iran through Life Cycle Assessment(LCA)methodology.The primary data were collected from 45 units of milk production through a field survey with the help of a structured questionnaire.The reliability was assessed using Cronbach’s alpha coefficient and was estimated an acceptable value of 0.91.The consumption of resources and emissions were allocated to a functional unit(FU)of one ton of milk.Impacts of emissions in five impact categories of global warming,acidification,eutrophication,photochemical oxidation and depletion of resources were investigated.The results showed that the characterization index for these impact categories were 1831 kg CO2 eq,7.97 kg SO2 eq,3.42 kg PO4^-3 eq,0.21 kg C2H4 eq and 838.39 MJ,respectively.Final indices for these impact categories were calculated as 0.24,0.28,0.076,0.017 and 0.046,respectively.Environmental index(EcoX)and resources depletion index(RDI)were obtained 0.61 and 0.04,respectively.In this study,the highest potential for environmental impacts of production revealed for acidification and followed by global warming impact category. | Hamzeh Soltanali Bagher Emadi Abbas Rohani Mehdi Khojastehpour Amin Nikkhah | 2015 | Information Processing in Agriculture2015，2，2： | 4 |
| 11 | Bicanalicular versus monocanalicular intubation after failed probing in congenital nasolacrimal duct obstruction显示文摘AIM:To investigate the clinical outcomes of different intubation techniques in the cases of failed primary probing.METHODS: This retrospective study was performed on338 patients with the diagnosis of congenital nasolacrimal duct obstruction with age 1-4y that had failed primary probing.Intubation was performed under light sedation in operating room and the stent was left 3mo in place.Clinical outcome was investigated 3mo after tube removal.RESULTS: Bicanalicular intubation method had higher complete and relative success rates compared to monocanalicular intubation(P =0.00).In addition,Monoka intubation had better outcomes compared to Masterka technique(P =0.046).No difference was found between genders but the higher the age,the better the outcomes with bicanalicular technique rather than monocanalicular.CONCLUSION: Overall success rate of bicanalicular intubation is superior to monocanalicular technique especially in older ages.Also,based upon our clinical outcomes,Masterka intubation is not recommended in cases of failed probing. | Mohammad Taher Rajabi Najmeh Zavarzadeh Alireza Mahmoudi Mohammad Karim Johari Seyedeh Simindokht Hosseini Yalda Abrishami Mohammad Bagher Rajabi | 2016 | International Journal of Ophthalmology(English edition)2016，9，10： | 4 |
| 12 | A Novel Distributed Optimal Adaptive Control Algorithm for Nonlinear Multi-Agent Differential Graphical Games显示文摘In this paper, an online optimal distributed learning algorithm is proposed to solve leader-synchronization problem of nonlinear multi-agent differential graphical games. Each player approximates its optimal control policy using a single-network approximate dynamic programming(ADP) where only one critic neural network(NN) is employed instead of typical actorcritic structure composed of two NNs. The proposed distributed weight tuning laws for critic NNs guarantee stability in the sense of uniform ultimate boundedness(UUB) and convergence of control policies to the Nash equilibrium. In this paper, by introducing novel distributed local operators in weight tuning laws, there is no more requirement for initial stabilizing control policies. Furthermore, the overall closed-loop system stability is guaranteed by Lyapunov stability analysis. Finally, Simulation results show the effectiveness of the proposed algorithm. | Majid Mazouchi Mohammad Bagher Naghibi-Sistani Seyed Kamal Hosseini Sani | 2018 | IEEE/CAA Journal of Automatica Sinica2018，5，1： | 3 |
| 13 | Evaluation of rabbit antibody response against 8 and 16 kDa recombinant subunits of antigen B from Echinococcus granulosus显示文摘Objective:To immunize rabbits with 12 and 16 kDa recombinant subunits of antigen B from Echinococcus granulosus(E.granulosus) and measuring polyclonal antibody and humoral immune response using ELISA and gel diffusion.Methods:Two mentioned antigens were cloned and expressed in expression vector and purified by affinity chromatography.Four young rabbits were selected and challenged intradermallt with yielded recombinant antigens.Rabbits’ sera were collected post infection and were tested using ELISA and gel diffusion for polyclonal antibody detection 10 days after last injection.Results:The specific antibody against the recombinant peptides was efficiently produced within 4 weeks post infection.Conclusions: Produced recombinants proteins could induce the immune response of the rabbits successfully. This process might improve the clarification of diagnosis and vaccination as regards hydatidosis. | Jahangir Abdi Bahram Kazemi Mohammad Hasan Karimfar Mohammad Bagher Rokni | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，5： | 3 |
| 14 | Islet transplantation and antioxidant management: A comprehensive review显示文摘Islet transplantation as a promising treatment for type 1 diabetes has received widespread attention. Oxidative stress plays an essential role in cell injury during islet isolation and transplantation procedures. Antioxidants have been used in various studies to improve islet transplantation procedures. The present study reviews the role of oxidative stress and the benefits of antioxidants in islet transplantation procedures. The bibliographical databases Pubmed and Scopus were searched up to November 2008. All relevant human and animal in-vivo and in-vitro studies, which investigated antioxidants on islets, were included. Almost all the tested antioxidants used in the in-vitro studies enhanced islet viability and insulin secretion. Better control of blood glucose after transplantation was the major outcome of antioxidant therapy in all in-vivo studies. The data also indicated that antioxidants improved islet transplantation procedures. Although there is still insuffi cient evidence to draw definitive conclusions about the efficacy of individual supplements, the benefi ts of antioxidants in islet isolation procedures cannot be ignored. | Seyed Sajad Mohseni Salehi Monfared Bagher Larijani Mohammad Abdollahi | 2009 | World Journal of Gastroenterology2009，15，10： | 3 |
| 15 | Lymphomatoid Granulomatosis with Splenomegaly and Pancytopenia显示文摘Lymphomatoid granulomatosis (LG) is an angiocentric lymphoproliferative disease. It usually involves lung, skin, and central nervous system, but splenomegaly and pancytopenia are the rare manifestations of the disease. We report a 15-year-old boy presented with fever, dry cough and dyspnea from two months ago, after admission patient had nodular lesions on the left leg and hepatosplenomegaly. Then he manifested neurologic signs such as seizure, aphasia and right-sided hemiplegia. Chest X-ray and CT scan revealed bilateral pulmonary nodules predominantly in lower lobes and peripheral lung fields. Laboratory exams showed pancytopenia. Skin biopsy was done, and histopathological examination and immunohistochemistry evaluation confirmed lymphomatoid granulomatosis. He was treated with steroid and cyclophosphamide but succumbed by neurologic involvement. | Abolhasan HALVANI Mohammad Bagher OWLIA Ramin SAMI | 2010 | 中国肺癌杂志2010，13，1： | 3 |
| 16 | Evaluation of renewable energies production potential in the Middle East:confronting the world’s energy crisis显示文摘Oil and fossil fuels,the main source of energy in the Middle East have obviously the most destructive effects on the environment and public health.The developed countries of the Middle East are faced with the crisis and energy security.This paper is about evaluating the energy demand/consumption in the Middle East.First,the position of energy consumption in the world and the Middle East is discussed.Next,the evaluation of the current potential of clean energy production from renewable energies is explained.Finally,according to related maps,charts and information presented for the condition of renewable energy which has been approved by the countries of the Middle East,the greatest places in some countries of this region are introduced and discussed. | Hamid BAHRAMPOUR Amir Khosro BEHESHTI MARNANI Mohammad Bagher ASKARI Mohammad Reza BAHRAMPOUR | 2020 | Frontiers in Energy2020，14，1： | 3 |
| 17 | Nanoparticles of quaternized chitosan derivatives as a carrier for colon delivery of insulin: Ex vivo and in vivo studies显示文摘 | Akbar Bayat Farid A. Dorkoosh Ahmad Reza Dehpour Leila Moezi Bagher Larijani Hans E. Junginger Morteza Rafiee-Tehrani | 2008 | International Journal of Pharmaceutics2008，，1： | 2 |
| 18 | 精准医学伦理问题综述显示文摘精准医学是针对每个个体的遗传特性和生活方式,而制定预防和治疗方案的新方法。欧美发达国家早在20世纪初就着眼于精准医学的研发,将基因测序技术与靶向药物研发及其相关的监管政策为发展重点,积极推动基于药物基因组学的新药创制与上市。我国精准医学起步晚,研发和应用相对落后,成功研发上市的相关药物仅占世界的0. 7%;相关伦理和法规建设也存在一定的滞后. | Pooneh Salari Bagher Larijani 郑君 | 2018 | 中国医学伦理学2018，31，9： | 2 |
| 19 | Pseudo four-component and regioselective synthesis of 4-amino-3,5-dicyano-6-arylphthalates using triethylamine catalyst显示文摘An efficient triethylamine-catalyzed synthesis of 4-amino-3,5-dicyano-6-arylphthalates is described.A one-pot,simple pseudo four-component reaction between arylaldehydes,dialkyl acetylenedicarboxylates, and twice as much malononitrile gave 4-amino-3,5-dicyano-6-arylphthalates in good to excellent yields. | Bagher Mohammadi Mansoor Shafieey Hamed Kazemi Ali Ramazani | 2013 | Chinese Chemical Letters2013，24，6： | 2 |
| 20 | Effect of Satureja khuzestanica essential oil on male rat fertility显示文摘 | Sulmaz Haeri Bagher Minaie Gholamreza Amin Shekoufeh Nikfar Reza Khorasani Hadi Esmaily Alinazar Salehnia Mohammad Abdollahi | 2006 | Fitoterapia2006，，7： | 2 |
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