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| 1 | Ontology-based Access Control for FAIR Data显示文摘This paper focuses on fine-grained,secure access to FAIR data,for which we propose ontology-based data access policies.These policies take into account both the FAIR aspects of the data relevant to access(such as provenance and licence),expressed as metadata,and additional metadata describing users.With this tripartite approach(data,associated metadata expressing FAIR information,and additional metadata about users),secure and controlled access to object data can be obtained.This yields a security dimension to the“A”(accessible)in FAIR,which is clearly needed in domains like security and intelligence.These domains need data to be shared under tight controls,with widely varying individual access rights.In this paper,we propose an approach called Ontology-Based Access Control(OBAC),which utilizes concepts and relations from a data set's domain ontology.We argue that ontology-based access policies contribute to data reusability and can be reconciled with privacy-aware data access policies.We illustrate our OBAC approach through a proof-of-concept and propose that OBAC to be adopted as a best practice for access management of FAIR data. | Christopher Brewster Barry Nouwt Stephan Raaijmakers Jack Verhoosel | 2020 | Data Intelligence2020，2，1： | 8 |
| 2 | Gynecologic oncologists involvement on ovarian cancer standard of care receipt and survival显示文摘AIM:To examine the influence of gynecologic oncolo-gists(GO) in the United States on surgical/chemotherapeutic standard of care(SOC), and how this translates into improved survival among women with ovarian cancer(OC).METHODS: Surveillance, Epidemiology, and End Result(SEER)-Medicare data were used to identify 11688 OC patients(1992-2006). Only Medicare recipients with an initial surgical procedure code(n = 6714) were included. Physician specialty was identified by linking SEER-Medicare to the American Medical Association Masterfile. SOC was defined by a panel of GOs. Multivariate logistic regression was used to determine predictors of receiving surgical/chemotherapeutic SOCand proportional hazards modeling to estimate the effect of SOC treatment and physician specialty on survival. RESULTS: About 34% received surgery from a GO and 25% received the overall SOC. One-third of women had a GO involved sometime during their care. Women receiving surgery from a GO vs non-GO had 2.35 times the odds of receiving the surgical SOC and 1.25 times the odds of receiving chemotherapeutic SOC(P < 0.01). Risk of mortality was greater among women not receiving surgical SOC compared to those who did [hazard ratio = 1.22(95%CI: 1.12-1.33), P < 0.01], and also was higher among women seen by non-GOs vs GOs(for surgical treatment) after adjusting for covariates. Median survival time was 14 mo longer for women receiving combined SOC. CONCLUSION: A survival advantage associated with receiving surgical SOC and overall treatment by a GO is supported. Persistent survival differences, particularly among those not receiving the SOC, require further investigation. | Sun Hee Rim Shawn Hirsch Cheryll C Thomas Wendy R Brewster Darryl Cooney Trevor D Thompson Sherri L Stewart | 2016 | World Journal of Obstetrics and Gynecology2016，5，2： | 3 |
| 3 | Characterization of solid dispersions of itraconazole and hydroxypropylmethylcellulose prepared by melt extrusion—part I显示文摘 | Geert Verreck Karel Six Guy Van den Mooter Lieven Baert Jef Peeters Marcus E. Brewster | 2002 | International Journal of Pharmaceutics2002，，1： | 2 |
| 4 | Thinking and Working Relationally: Interviewing and Constructing Hypotheses to Create Compassionate Understanding显示文摘 | Marcia Sheinberg Mary Kim Brewster | 2014 | Fam. Proc2014，，： | 2 |
| 5 | Radiative Propertiesof Burning Alumin um Droplets 显示文摘 | Brewster M Q Dale MT | 1988 | Combustion and Flame1988，72，： | 2 |
| 6 | Cross - resistance of serval diclofop resistant wild oat(Avena fatua)biotypes from the Willamette Valley of Oregen显示文摘 | SEEFELDT S S GEALY D R BREWSTER B D | 1994 | Weed Sci1994，42，： | 2 |
| 7 | Infrapopliteal balloon angioplasty for the treatment of chronic occlusive disease显示文摘 | Mark F. Conrad Jeanwan Kang Richard P. Cambria David C. Brewster Michael T. Watkins Christopher J. Kwolek Glenn M. LaMuraglia | 2009 | Journal of Vascular Surgery2009，，： | 2 |
| 8 | Chemotherapy options in elderly and frail patients with metastatic colorectal cancer (MRC FOCUS2): an open-label, randomised factorial trial显示文摘 | Matthew T Seymour Lindsay C Thompson Harpreet S Wasan Gary Middleton Alison E Brewster Stephen F Shepherd M Sinead O’Mahony Timothy S Maughan Mahesh Parmar Ruth E Langley | 2011 | The Lancet2011，，9779： | 2 |
| 9 | 环糊精在注射剂中应用的前景显示文摘在水中难溶或不大稳定的药物难以做成制剂注射给药,这是一个长期存在的恼人的问题。有人曾用药物前体、有机助溶剂、乳剂、脂质体及胶束化等方法来解决药理活性成分的水不相容问题,但注射给药对低毒性的绝对需要阻碍了这些方法的应用。环糊精能与许多药物形成包含物,实质上能增加药物的水溶性,但由于环糊精有肾毒性,排除了用于注射剂的可能。羟基烃基-β-环糊精似乎比未取代或烃基化环糊精的毒性低,有可能应用于静脉注射。 | Brewster ME 盛坤贤 | 1990 | 国外医药(合成药.生化药.制剂分册)1990，11，6： | 2 |
| 10 | An osmosensing signal transduction pathway in yeast 显示文摘 | BREWSTER JL DE VALOIR T DWYER N | 1993 | Science1993，259，5102： | 1 |
| 11 | Knowledge transfer and the management of expatriation 显示文摘 | B JAIME BREWSTER | 2001 | Thunderbird International Business Review2001，43，1： | 1 |
| 12 | The role of angioplasty to improve inflow for infrainguinal bypasses显示文摘 | Brewster DC | 1995 | Eur J Vase Endovasc Surg1995，9，3： | 1 |
| 13 | Endoplasmic reticulum stress and trophic factor withdrawal activate distinct signaling cascades that induce glycogen synthase kinase-3 beta and a caspase-9-dependent apoptosis in cerebellar granule neurons显示文摘 | Brewster J L Linseman D A Bouchard R J Loucks F A Precht T A Esch E A Heidenreich K A | | 0，，03： | 1 |
| 14 | Cyclodextrin-based pharmaceutics : past, pl~sent and future显示文摘 | Davis M E Brewster M E | 2004 | Nat Rev Drug Discovery2004，3，： | 1 |
| 15 | Self-association of cyclodextrins and cyclodextrin complexes显示文摘 | Loftsson Thorsteinn Masson Mar Brewster E | 2004 | J Phann Sci2004，93，5： | 1 |
| 16 | Self-association of cyclodextrins and cyclodextrin complexes 显示文摘 | Loftsson T Masson M Brewster ME | 2004 | J Pharm Sci2004，93，5： | 1 |
| 17 | Chemosensitization of human prostate cancer using antisense agents tareting the type1 insulin - like growth factor receptor显示文摘 | Hellawell GO Ferguson DJ Brewster SF | 2003 | BJU Int2003，91，3： | 1 |
| 18 | Force and motion analysis of the normal, diseased, and prosthetic ankle joint 显示文摘 | Stauffer RN Chao EY Brewster RC | 1977 | Clin Orthop Relat Res1977，，127： | 1 |
| 19 | Biodiversity of ant species along a disturbance gradient in residential environments of Puerto Rico显示文摘 | Brown P H Miller D M Brewster C C | 2013 | Urban Ecosystems2013，16，2： | 1 |
| 20 | An osmosensing signal transduction pathway in yeast显示文摘 | Brewster JL de Valoir T Dwyer ND | 1993 | Science1993，259，5102： | 1 |
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