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| 1 | Update on surgical treatment of pancreatic neuroendocrine neoplasms显示文摘Pancreatic neuroendocrine neoplasms(PNENs) are rare and account for only 2%-4% of all pancreatic neoplasms. All PNENs are potential(neurendocrine tumors PNETs) or overt(neuroendocrine carcinomas PNECs) malignant,but a subset of PNETs is low-risk. Even in case of low-risk PNETs surgical resection is frequently required to treat hormone-related symptoms and to obtain an appropriate pathological diagnosis. Low-risk PNETs in the body and the tail are ideal for minimallyinvasive approaches which should be tailored to the individual patient. Generally,surgeons must aim for parenchyma sparing in these cases. In high-risk and malignant PNENs,indications for tumor resection are much wider than for pancreatic adenocarcinoma,in many cases due to the relatively benign tumor biology. Thus,patients with locally advanced and metastatic PNETs may benefit from extensive resection. In experienced hands,even multi-organ resections are accomplished with acceptable perioperative morbidity and mortality rates and are associated with excellent long term survival. However,poorly differentiated neoplasms with high proliferation rates are associated with a dismal prognosis and may frequently only be treated with chemotherapy. The evidence on surgical treatment of PNENs stems from reviews of mostly singlecenter series and some analyses of nation-wide tumor registries. No randomized trial has been performed to compare surgical and non-surgical therapies in potentially resectable PNEN. Though such a trial would principally be desirable,ethical considerations and the heterogeneity of PNENs preclude realization of such a study. In the current review,we summarize recent advances in the surgical treatment of PNENs. | Jan G D’Haese Chiara Tosolini Güralp O Ceyhan Bo Kong Irene Esposito Christoph W Michalski J?rg Kleeff | 2014 | World Journal of Gastroenterology2014,20,38: | 4 |
| 2 | A chemical method to graft carbon nanotubes onto a carbon fiber显示文摘 | Abdelghani Laachachi Alexandre Vivet Gérard Nouet Bessem Ben Doudou Christophe Poilane Jun Chen Jin Bo bai M’Hamed Ayachi | 2007 | Materials Letters2007,,3: | 3 |
| 3 | DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice显示文摘 | Meira Lisiane B Bugni James M Green Stephanie L Lee Chung-Wei Pang Bo Borenshtein Diana Rickman Barry H Rogers Arlin B Moroski-Erkul Catherine A McFaline Jose L Schauer David B Dedon Peter C Fox James G Samson Leona D | 2008 | Journal of Clinical Investigation2008,,7: | 2 |
| 4 | Stent Thrombosis in New-Generation Drug-Eluting Stents in Patients With STEMI Undergoing Primary PCI显示文摘 | Giovanna Sarno Bo Lagerqvist Johan Nilsson Ole Frobert Kristina Hambraeus Christoph Varenhorst Ulf J. Jensen Tim T?dt Matthias G?tberg Stefan K. James | 2014 | Journal of the American College of Cardiology2014,,1: | 2 |
| 5 | Cystatin C as a marker of GFR-history,indications,and future research显示文摘 | Filler G Bo kenkamp Hofmann W | | 0,,: | 2 |
| 6 | Influence of Eutrophication on the Distribution of Total Mercury and Methylmercury in Hydroelectric Reservoirs显示文摘 | Meng Bo Feng X B Chen C X Qiu G L Sommar J Guo Y N Liang P Wan Q | 2010 | EN2010,,5: | 2 |
| 7 | Altered expression patterns of group Ⅰ and Ⅱ metabotropic glutamate receptors in multiple sclerosis显示文摘 | Geurts JJ Wolswijk G Bo L | 2003 | Brain2003,126,8: | 1 |
| 8 | The coolstreaming: Design, theory and practice显示文摘 | XIE Su-su LI Bo KEUNG G Y | 2007 | IEEE Transactions on Multimedia Special Issue on Content Storage and Delivery in Peer-to-Peer Network2007,9,8: | 1 |
| 9 | Effectiveness of a lifestyle intervention on metabolic syndrome:a randomized controlled trial显示文摘 | Bo S Ciccone G Baldi C | 2007 | J Gen Intern Med2007,22,12: | 1 |
| 10 | Selective proges terone receptor modulators and progesterone antagonists: mechanisms of action and clinical applications显示文摘 | Nathalie C B Meduri G Bo'uchard P | 2005 | Hum Re prod Update2005,11,: | 1 |
| 11 | Force amplification response of actin filaments under confined compression 显示文摘 | GREENE G ANDERSON T ZENG Hong Bo | 2009 | Proc Nat Acad SciUSA2009,106,2: | 1 |
| 12 | C-reactive protein and tumor necrosis factor-alpha in gestational hyperglycemia显示文摘 | Signorile A Bo S Menato G | | 0,,09: | 1 |
| 13 | Isolation of a strain of Acidithiobacillus caldus and its role in bioleaching of chalcopyrite显示文摘 | ZHOU Q G BO F BO Z H XI L JIAN G FEI L F HUA C X | 2007 | World Journal of Microbiology and Biotechnology2007,23,9: | 1 |
| 14 | Sulfamic acid as a cost-effective and recyclable catalyst for liquid Beckmann rearrangement,a green process to produce amides from ketoximes without waste显示文摘 | Bo W Yanlong G Cheng L | 2004 | Tetrahedron Lett2004,45,: | 1 |
| 15 | Dietary fat and gestation hyperglycaemia显示文摘 | Bo S Menato G Lezo A | 2001 | Diabetologia2001,44,: | 1 |
| 16 | Morphology and size control of Ni-Al layered double hydroxides using chitosan as template 显示文摘 | Li Bo He Jing David G | 2006 | Journal of Physics and Chemistry of Solids2006,67,: | 1 |
| 17 | Bovine lacto ferrin for Helicobacter pylori eradication: an open, randomized, muhicentre study显示文摘 | DI MARIO F ARAGONA G DAL BO N | 2006 | Aliment Pharmacol Ther2006,23,8: | 1 |
| 18 | Ovarian superstimulatory response relative to follicular wave emergence in heifers显示文摘 | Nasser L Adams G P Bo G A | 2003 | Theriogenology2003,40,: | 1 |
| 19 | Transplantation current stature and future directions显示文摘 | Chesen BO Leyland-jones B Sarosy G | 1989 | Ann Intern Med1989,110,1: | 1 |
| 20 | Role of platinum deposited on TiO2 in phenol photocatalytic oxidation 显示文摘 | Bo S Alexander V V Panagiotis G S | 2003 | Langmuir2003,19,: | 1 |