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1Update on surgical treatment of pancreatic neuroendocrine neoplasms显示文摘Pancreatic neuroendocrine neoplasms(PNENs) are rare and account for only 2%-4% of all pancreatic neoplasms. All PNENs are potential(neurendocrine tumors PNETs) or overt(neuroendocrine carcinomas PNECs) malignant,but a subset of PNETs is low-risk. Even in case of low-risk PNETs surgical resection is frequently required to treat hormone-related symptoms and to obtain an appropriate pathological diagnosis. Low-risk PNETs in the body and the tail are ideal for minimallyinvasive approaches which should be tailored to the individual patient. Generally,surgeons must aim for parenchyma sparing in these cases. In high-risk and malignant PNENs,indications for tumor resection are much wider than for pancreatic adenocarcinoma,in many cases due to the relatively benign tumor biology. Thus,patients with locally advanced and metastatic PNETs may benefit from extensive resection. In experienced hands,even multi-organ resections are accomplished with acceptable perioperative morbidity and mortality rates and are associated with excellent long term survival. However,poorly differentiated neoplasms with high proliferation rates are associated with a dismal prognosis and may frequently only be treated with chemotherapy. The evidence on surgical treatment of PNENs stems from reviews of mostly singlecenter series and some analyses of nation-wide tumor registries. No randomized trial has been performed to compare surgical and non-surgical therapies in potentially resectable PNEN. Though such a trial would principally be desirable,ethical considerations and the heterogeneity of PNENs preclude realization of such a study. In the current review,we summarize recent advances in the surgical treatment of PNENs.Jan G D’Haese Chiara Tosolini Güralp O Ceyhan Bo Kong Irene Esposito Christoph W Michalski J?rg Kleeff 2014World Journal of Gastroenterology2014,20,38:4
2A chemical method to graft carbon nanotubes onto a carbon fiber显示文摘Abdelghani Laachachi Alexandre Vivet Gérard Nouet Bessem Ben Doudou Christophe Poilane Jun Chen Jin Bo bai M’Hamed Ayachi 2007Materials Letters2007,,3:3
3DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice显示文摘Meira Lisiane B Bugni James M Green Stephanie L Lee Chung-Wei Pang Bo Borenshtein Diana Rickman Barry H Rogers Arlin B Moroski-Erkul Catherine A McFaline Jose L Schauer David B Dedon Peter C Fox James G Samson Leona D 2008Journal of Clinical Investigation2008,,7:2
4Stent Thrombosis in New-Generation Drug-Eluting Stents in Patients With STEMI Undergoing Primary PCI显示文摘Giovanna Sarno Bo Lagerqvist Johan Nilsson Ole Frobert Kristina Hambraeus Christoph Varenhorst Ulf J. Jensen Tim T?dt Matthias G?tberg Stefan K. James 2014Journal of the American College of Cardiology2014,,1:2
5Cystatin C as a marker of GFR-history,indications,and future research显示文摘Filler G Bo kenkamp Hofmann W 0,,:2
6Influence of Eutrophication on the Distribution of Total Mercury and Methylmercury in Hydroelectric Reservoirs显示文摘Meng Bo Feng X B Chen C X Qiu G L Sommar J Guo Y N Liang P Wan Q 2010EN2010,,5:2
7Altered expression patterns of group Ⅰ and Ⅱ metabotropic glutamate receptors in multiple sclerosis显示文摘Geurts JJ Wolswijk G Bo L 2003Brain2003,126,8:1
8The coolstreaming: Design, theory and practice显示文摘XIE Su-su LI Bo KEUNG G Y 2007IEEE Transactions on Multimedia Special Issue on Content Storage and Delivery in Peer-to-Peer Network2007,9,8:1
9Effectiveness of a lifestyle intervention on metabolic syndrome:a randomized controlled trial显示文摘Bo S Ciccone G Baldi C 2007J Gen Intern Med2007,22,12:1
10Selective proges terone receptor modulators and progesterone antagonists: mechanisms of action and clinical applications显示文摘Nathalie C B Meduri G Bo'uchard P 2005Hum Re prod Update2005,11,:1
11Force amplification response of actin filaments under confined compression 显示文摘GREENE G ANDERSON T ZENG Hong Bo 2009Proc Nat Acad SciUSA2009,106,2:1
12C-reactive protein and tumor necrosis factor-alpha in gestational hyperglycemia显示文摘Signorile A Bo S Menato G 0,,09:1
13Isolation of a strain of Acidithiobacillus caldus and its role in bioleaching of chalcopyrite显示文摘ZHOU Q G BO F BO Z H XI L JIAN G FEI L F HUA C X 2007World Journal of Microbiology and Biotechnology2007,23,9:1
14Sulfamic acid as a cost-effective and recyclable catalyst for liquid Beckmann rearrangement,a green process to produce amides from ketoximes without waste显示文摘Bo W Yanlong G Cheng L 2004Tetrahedron Lett2004,45,:1
15Dietary fat and gestation hyperglycaemia显示文摘Bo S Menato G Lezo A 2001Diabetologia2001,44,:1
16Morphology and size control of Ni-Al layered double hydroxides using chitosan as template 显示文摘Li Bo He Jing David G 2006Journal of Physics and Chemistry of Solids2006,67,:1
17Bovine lacto ferrin for Helicobacter pylori eradication: an open, randomized, muhicentre study显示文摘DI MARIO F ARAGONA G DAL BO N 2006Aliment Pharmacol Ther2006,23,8:1
18Ovarian superstimulatory response relative to follicular wave emergence in heifers显示文摘Nasser L Adams G P Bo G A 2003Theriogenology2003,40,:1
19Transplantation current stature and future directions显示文摘Chesen BO Leyland-jones B Sarosy G 1989Ann Intern Med1989,110,1:1
20Role of platinum deposited on TiO2 in phenol photocatalytic oxidation 显示文摘Bo S Alexander V V Panagiotis G S 2003Langmuir2003,19,:1
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