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| 1 | Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density显示文摘 | W.S Simonet D.L Lacey C.R Dunstan M Kelley M.-S Chang R Lüthy H.Q Nguyen S Wooden L Bennett T Boone G Shimamoto M DeRose R Elliott A Colombero H.-L Tan G Trail J Sullivan E Davy N Bucay L Renshaw-Gegg T.M Hughes D Hill W Pattison P Campbell S Sander G Van | 1997 | Cell1997，，2： | 6 |
| 2 | Fecal lactoferrin accurately reflects mucosal inflammation in inflammatory bowel disease显示文摘BACKGROUND Studies have demonstrated a potential role for fecal biomarkers such as fecal calprotectin(FC)and fecal lactoferrin(FL)in monitoring inflammatory bowel diseases(IBD)-Crohn's disease(CD)and ulcerative colitis(UC).However,their correlation to endoscopic scores,disease severity and affected intestinal surface has not been extensively investigated.AIM To correlate FL,and for comparison white blood cell(WBC)and C-reactive protein(CRP),with endoscopic scores,disease extent and location in CD and UC.METHODS Retrospective analysis in 188 patients who had FL,CRP and WBC determined within 30 d of endoscopy.Disease location,disease extent(number of intestinal segments involved),disease severity(determined by endoscopic scores),timing of FL testing in relation to colonoscopy,as well as the use of effective fast acting medications(steroids and biologics)between colonoscopy and FL measurement,were recorded.RESULTS In 131 CD and 57 UC patients,both CRP and FL-but not WBC-distinguished disease severity(inactive,mild,moderate,severe).In patients receiving fastacting(steroids or biologics)treatment in between FL and colonoscopy,FL showed a higher correlation to endoscopic scores when tested before vs after the procedure(r=0.596,P<0.001,vs r=0.285,P=0.15 for the Simple Endoscopic Score for CD;and r=0.402,P=0.01 vs r=0.054 P=0.84 for Disease Activity Index).Finally,FL was significantly correlated with the diseased mucosal surface(colon-ileocolon>small bowel)and the number of inflamed colon segments.CONCLUSION FL and CRP separated disease severity categories with FL showing lower discriminating P-values.FL showed a close correlation with the involved mucosal surface and with disease extent and was more closely correlated to endoscopy when determined before the procedure–this indicating that inflammatory activity changes associated with therapy might be rapidly reflected by FL levels.FL can accurately and timely characterize intestinal inflammation in IBD. | Marrieth G Rubio Kofi Amo-Mensah James M Gray Vu Q Nguyen Sam Nakat Douglas Grider Kim Love James H Boone Dario Sorrentino | 2019 | World Journal of Gastrointestinal Pathophysiology2019，10，5： | 4 |
| 3 | Chemical oxidation kinetics ofpyrite in bioleaching processes 显示文摘 | Boon M Heijnen J J | 1998 | Hydrometallurgy1998，，1： | 2 |
| 4 | Chemical oxidation kinetics of pyrite in bioleaching processes显示文摘 | Boon M Heijnen J J | 1998 | Hydrometallurgy1998，48，1： | 1 |
| 5 | Vascular Dysmorphogenesis Caused by an Activating Mutation in the Receptor Tyrosine Kinase TIE2 显示文摘 | Vikkula M Boon LM Carraway KL 3rd | 1996 | Cell1996，87，11： | 1 |
| 6 | Size effects of PVP Pd nanoparticles on the catalytic Suzuki reactions inaqueous solution显示文摘 | Li Y Boone E J *'1-Sayed M A | 2002 | Langmuir2002，18，12： | 1 |
| 7 | H5N1 influenza virus pathogenesis in genetically diverse mice is mediated at the level of viral load显示文摘 | Boon AC Finkelstein D Zheng M | | 0，，05： | 1 |
| 8 | Synthe- sis of LD-Hepp and Kdo containing di- and tetrasac- charide derivatives of Neisseriu meningitidis inner-core region via iodonium ion promoted glycosidations 显示文摘 | Boons G J Van D F L Vander K P M | 1992 | Tetrahedron1992，48，5： | 1 |
| 9 | Biofuel cells select for microbial consortia that self-mediate electron transfer显示文摘 | Rabaey K Boon N Hofte M | 2004 | Appl Environ Microbial2004，70，9： | 1 |
| 10 | The use of off-gas analyses and stoichiometry in the biooxidation kinetics of sulphide minerals显示文摘 | Boon M | 1998 | Hydrometallurgy1998，48，1： | 1 |
| 11 | Vascular dysmorphogenesis caused by an activating mutation in the receptor tyrosine kinase tie-2显示文摘 | Vikkula M Boon L Carraway K | 1996 | Cell1996，87，7： | 1 |
| 12 | Effects of density on metamorphosis of bullfrogs in a single season显示文摘 | Provenzano S E Boone M D | 2009 | Journal of Herpetology2009，43，1： | 1 |
| 13 | Tumor regressions observed in patients with metastatic melanoma treated with an antigenic peptide encoded by gene MAGE-3 and presented by HLA-A1显示文摘 | Marchand M Van Baren N Boon T | 1999 | Int J Cancer1999，80，2： | 1 |
| 14 | Biofuel cells select for microbial consortia that self-mediate electron transfer显示文摘 | RABAEY K BOON N SICILIANO S D VERHAEGE M VERSTRAETE W | 2004 | Appl Environ Microbiol2004，70，9： | 1 |
| 15 | Direct temperature resolved HRMS of fire-retarded polymers by in-Source PyMS on an external ion source fourier transform ion cyclotron resonance mass spectrometer显示文摘 | Heeren R M A De Koster C G Boon J J | 1995 | Analytical Chemistry1995，67，21： | 1 |
| 16 | Spatial Sound Reproduction Based on Wave Field Synthsis显示文摘 | M M Boone | 1995 | J A E S1995，43，12： | 1 |
| 17 | De-mand articulation in emerging technologies: intermediary user organisations as co-producers? 显示文摘 | BOON W P C MOORS E H M KUHLMANN S | 2010 | Research Policy2010，40，2： | 1 |
| 18 | Desorption of CO from Ru (001) induced by near-infrared femtosecond laser pulse显示文摘 | Funk S Boon M Denzler D N | 2000 | J Chem Phys2000，112，22： | 1 |
| 19 | Oxidation, Kinetics of Zinc Sulphide with Thiobacillus ferrooxidans 显示文摘 | Boon M Snider M Hansford G S | 1998 | Hydromrtallurgy1998，48，2： | 1 |
| 20 | Congenital hemangioma:evidence of accelerated involution显示文摘 | BOON L M ENJOLRAS O MULLIKEN J B | 1996 | J Pediatr1996，128，3： | 1 |
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