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| 1 | 大气二氧化氮与每日总死亡率、心血管和呼吸系统疾病死亡率的短期关联:398个城市的多中心分析显示文摘目的:采用统一的分析方案,评估全球多个国家/地区的二氧化氮(NO_(2))与总死亡率、心血管和呼吸系统疾病死亡率之间的短期关联。研究设计:采用两阶段的时间序列分析方法、过度离散的广义线性模型和多水平meta分析。研究地点:22个低到高收入国家/地区的398个城市。主要结局指标:1973—2018年逐日总死亡人数(6280万人)、心血管疾病死亡人数(1970万人)和呼吸系统疾病死亡人数(550万人)。结果:平均而言,NO_(2)浓度在滞后1天(前1天)每增加10μg/m^(3),会导致总死亡率、心血管和呼吸系统疾病死亡率分别增加0.46%(95%可信区间0.36%~0.57%)、0.37%(0.22%~0.51%)、0.47%(0.21%~0.72%)。在对共污染物(PM_(10)、PM_(2.5)、臭氧、二氧化硫和一氧化碳)进行调整后,这些关联仍然很稳定。所有3种死因的暴露-反应曲线几乎是线性的,没有明显的阈值。在398个城市中,可归因于高过假定零水平的NO_(2)浓度造成的死亡比例为1.23%(95%可信区间0.96%~1.51%)。结论:这项多中心研究提供了关于NO_(2)短期暴露与总死亡率、心血管和呼吸系统死亡风险之间的独立和线性关联的关键证据,说明通过加强NO_(2)的控制和监管限制标准,可获得人群水平的健康收益。 | 孟夏 刘聪(校) 陈仁杰 郑湃(译) 阚海东(校) Francesco Sera Ana Vicedo-Cabrera Ai Milojevic Maria Guo Yuming Tong Shilu Micheline de Sousa Zanotti Stagliorio Coelh Paulo Hilario Nascimento Saldiva Eric Lavigne Patricia Matus Correa Nicolas Valdes Ortega Samuel Osorio Garcia Jan Kysely Ales Urban Hans Orru Marek Maasikmets Jouni J K Jaakkola Niilo Ryti Veronika Huber Alexandra Schneider Klea Katsouyanni Antonis Analitis Masahiro Hashizume Yasushi Honda Chris Fook Sheng Ng Baltazar Nunes João Paulo Teixeira Iulian Horia Holobaca Simona Fratianni Ho Kim Aurelio Tobias Carmeníniguez Bertil Forsberg ChristoferÅström Martina S Ragettli Yue-Liang Leon Guo Shih-Chun Pan Shanshan Li Michelle L Bell Antonella Zanobetti Joel Schwartz Tangchun Wu Antonio Gasparrini | 2021 | 英国医学杂志中文版2021，24，8： | 7 |
| 2 | Spatial patterns and chemical characteristics of root biomass in ecosystems of the Patagonian Monte disturbed by grazing显示文摘 | Rodriguez M V Bertiller M B Sain C L | 2007 | Journal of Arid Environments2007，70，1： | 1 |
| 3 | Seedling recruitment of perennial grasses in degraded areas of the Patagonian Monte显示文摘 | Bisigato A J Bertiller M B | 2004 | Journal of Range Management2004，57，： | 1 |
| 4 | Soil nitrogen dynamics in northeastern Patagonia steppe under different precipitation regiones显示文摘 | Mazzarino M J Bertiller M B Sain C | 1998 | Plant and Soil1998，202，： | 1 |
| 5 | Function al and structural landscape indicators of intensification, resilience and resistance in agroecosystems in southern Argentina based on remotely sensed data显示文摘 | ARES J BERTILLER M H' ECTOR DEL VALLE | 2001 | Landscape Ecology2001，16，： | 1 |
| 6 | Seasonal variation in the seed bank of a Patagonian grassland in relation to grazing and topography显示文摘 | Bertiller M B | 1992 | Journal of Vegetation Science1992，3，1： | 1 |
| 7 | Precipitation and landscape related effects on soil moisture in semi-arid range lands of Patagonia显示文摘 | Coronato F R Bertiller M B | 1996 | Journal of Arid Environments1996，34，： | 1 |
| 8 | Grazing effects on patchy dryland vegetation in northern Patagonia显示文摘 | Bisigato A J Bertiller M B | 1997 | Journal of Arid Environments1997，36，4： | 1 |
| 9 | Grazing effects on sustainable semiarid rangelands in Patagonia: the state and dynamics of the soil seed bank显示文摘 | BERTILLER M B | 1996 | Environ Manage1996，20，1： | 1 |
| 10 | Grazing effects on patchy dry land vegetation in northern Patagonia 显示文摘 | BISIGATO A J BERTILLER M B | 1997 | J Arid Environ1997，36，4： | 1 |
| 11 | Biological interactions at different spatial scales in the Monte desert of Argentina显示文摘 | Bertiller M B Marone L Baldi R | 2009 | Journal of Arid Environments2009，73，2： | 1 |
| 12 | Grazing effects on sustainable semiarid rangelands in Patagonia:the state and dynamics of the soil seed bank显示文摘 | Bertiller M B | 1996 | Environmental Management1996，20，1： | 1 |
| 13 | Effect of fine-scale spatial variation of soil nitrogen on the performance of the sexes of Poa ligularis in patchy ecosystems of northern Patagonia显示文摘 | Bertiller M B Sain C L Carrera A L | 2002 | International Journal of Plant Sciences2002，163，3： | 1 |
| 14 | Leaf litterfall, fineroot production, and decomposition in shrublands with different canopy structure induced by grazing in the Patagonian Monte, Argentina 显示文摘 | CARRERA A L BERTILLER M B LARREGUY C | 2008 | Plant and Soil2008，311，： | 1 |
| 15 | Understanding the meaning of accuracy, trueness and precision显示文摘 | ANTONIO M MARINA P BERTIL M | 2007 | Accred Qual Assur2007，12，： | 1 |
| 16 | Plant phenology, leaf traits and leaf litterfall of contrasting life forms in the arid Patagonian Monte, Argentina 显示文摘 | Campanella M V Bertiller M B | 2008 | Journal of Vegetation Science2008，19，1： | 1 |
| 17 | Small Changes in Troponin T Levels Are Common in Patients With Non–ST-Segment Elevation Myocardial Infarction and Are Linked to Higher Mortality显示文摘 | Christian Bjurman M?rten Larsson Per Johanson Max Petzold Bertil Lindahl Michael L.X. Fu Ola Hammarsten | 2013 | Journal of the American College of Cardiology2013，，： | 1 |
| 18 | Are fine roots of both shrubs and perennial grasses able to occupy the upper soil layer? A case study in the arid Patagonian Monte with non-seasonal precipitation显示文摘 | Rodriguez M V Bertiller M B Bisigato A | | 0，，1： | 1 |
| 19 | Stent implantation,but not pathogen burden,is associated with plasma C-reactive protein and interleukin-6levels after percutaneous coronary intervention in patients with stable angina pectoris显示文摘 | Saleh Nawsad M D Svane Bertil M D Jens M D | 2005 | AM Heart J2005，149，5： | 1 |
| 20 | Detection of Mycoplas- ma neumoniae by using the polymerase chain reaction 显示文摘 | Bernel C Garret M Bertille de B | 1989 | Clin Microbiol1989，27，11： | 1 |
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