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| 1 | 先天性心脏病中的肺动脉高压:来自一项荷兰注册研究的流行病学结果显示文摘背景:与先天性心脏病有关的肺动脉高压(PAH),通常是大量体循环向肺循环分流的结果,常常导致右室心力衰竭和早期死亡。本研究旨在确定一项先天性心脏病国家注册研究所登记成年患者中的PAH患病率,评价患者特征和PAH之间的关系。 | Duffels M.G.J. Engelfriet P.M. Berger R.M.F. B.J.M. Mulder 韩瑞娟 | 2007 | 世界核心医学期刊文摘(心脏病学分册)2007，，11： | 4 |
| 2 | 法洛四联症患者肺动脉瓣置换后自体移植物功能的长期随访显示文摘Aims: To analyse the long-term outcomes after pulmonary valve replacement(PVR) in patients with a previous correction for tetralogy of Fallot. Methods and results: In a retrospective study, 158 adult patients with a diagnosis of tetralogy of Fallot, who had undergone a PVR after initial total correction in childhood, were identified from the CONCOR(CONgenital CORvitia) registry. All patients underwent 175 PVRs between June 1986 and June 2005. To analyse the predictors for homograft dysfunction and adverse events(death, reoperations, balloon angioplasty), Cox-regression analysis was performed. Overall freedom from significant homograft dysfunction was 66%after 5 years and 47%after 10 years. We could not identify predictors for combined homograft dysfunction. Event-free survival was 78%at 10 years and 68%at 15 years after PVR. Both early significant pulmonary regurgitation(PR)(HR 6.8, P=0.017) and pulmonary stenosis(PS)(HR 4.0, P=0.037) after surgery were associated with adverse events. When analysing direct post-operative PR or PS,we observed that in patients with severe, pre-operative PR, right ventricular aneurysm/patch resection resulted in a lower post-operative PR(mean difference grade 0.38±0.14, P=0.01). Less significant post-operative PS was associated with a higher diameter of the homograft(HR 0.37, P=0.006). Conclusion: While 47%of the patients in our study were free from homograft dysfunction at 10 years after PVR, event-free survival after PVR remained fairly good(78%). Significant residual lesions directly after surgery influenced event-free survival. A smaller diameter of the pulmonary homograft and severe pre-surgical PR were related to early homograft dysfunction after surgery. | Oosterhof T. Meijboom F.J. Vliegen H.W. B.J.M. Mulder 郭俊 | 2006 | 世界核心医学期刊文摘(心脏病学分册)2006，，12： | 4 |
| 3 | Accumulation of Ultrasmall Superparamagnetic Particles of Iron Oxide in Human Atherosclerotic Plaques Can Be Detected by In Vivo Magnetic Resonance Imaging显示文摘 | M. E. Kooi V. C. Cappendijk K. B.J.M. Cleutjens A. G.H. Kessels P. J.E.H.M. Kitslaar M. Borgers P. M. Frederik M. J.A.P. Daemen J. M.A. van Engelshoven | 2003 | Circulation: Journal of the American Heart Association2003，，19： | 1 |
| 4 | The effects of the multispecies probiotic mixture Ecologic?Barrier on migraine: results of an open-label pilot study显示文摘 | N.M. de Roos C.G.T. Giezenaar J.M.P Rovers B.J.M. Witteman M.G. Smits S. van Hemert | 2015 | Beneficial Microbes2015，，1： | 1 |
| 5 | Prevalence of oropharyngeal dysphagia in Parkinson’s disease: A meta-analysis显示文摘 | J.G. Kalf B.J.M. de Swart B.R. Bloem M. Munneke | 2011 | Parkinsonism and Related Disorders2011，，4： | 1 |
| 6 | Circulating DNA is a non-invasive prognostic factor for survival in non-small cell lung cancer显示文摘 | Miep A. van der Drift Bernard E.A. Hol Corné H.W. Klaassen Clemens F.M. Prinsen Yvonne A.W.G. van Aarssen Rogier Donders Jos W.J. van der Stappen P.N. Richard Dekhuijzen Henricus F.M. van der Heijden Frederik B.J.M. Thunnissen | 2009 | Lung Cancer2009，，2： | 1 |
| 7 | Disruption of the Cathepsin K Gene Reduces Atherosclerosis Progression and Induces Plaque Fibrosis but Accelerates Macrophage Foam Cell Formation显示文摘 | E Lutgens S P.M. Lutgens B C.G. Faber S Heeneman M M.J. Gijbels M P.J. de Winther P Frederik I van der Made A Daugherty A M. Sijbers A Fisher C J. Long P Saftig D Black M J.A.P. Daemen K B.J.M. Cleutjens | 2006 | Circulation2006，，： | 1 |
| 8 | Designing continuous safety improvement within chemical industrial areas显示文摘 | G.L.L. Reniers B.J.M. Ale W. Dullaert K. Soudan | 2008 | Safety Science2008，，5： | 1 |
| 9 | 西德肉用牛的生产、测定和选育制度显示文摘西德的牛在全年或全年的大部分时间里都是进行集约化舍饲的,喂的是青贮饲料、干草和精饲料。以乳肉兼用品种为主。选种的重点是增加奶量和改进15—18个月的瘦公牛的肉质。 西德有大量的活牛出口贸易,但是所需要的牛肉和小牛肉,34%靠进口。 农场和牛群的规模以澳洲标准来衡量都比较小,因此需要集中进行性能和后裔测定。由于广泛采用了人工授精,使得经过精选的少量良种公牛的优良遗传物体得到了广泛传播。 对西德两个州的选种和测定方案进行了比较。这些方案是按照良种公牛与高产母牛的计划配种进行的。在性能测定之后进行精液测定和后裔测定,后者指对种牛的女儿和儿子分别测定其繁殖、产奶、产肉能力。对于不加限制地使用人工授精的公牛,在约五岁半时最后选定。 | B.J.M.霍兰德 李崇瑾 | 1979 | 世界农业1979，，7： | 0 |
| 10 | 马方综合征患者远离主动脉根部的远端扩张 | Engelfriet P.M. Boersma E. Tijssen J.G.P. B.J.M. Mulder 郭俊 | 2007 | 世界核心医学期刊文摘(心脏病学分册)2007，0，1： | 0 |
| 11 | 眼咽肌营养不良患者的上睑下垂加重其吞咽困难显示文摘Background: Ptosis and dysphagia are important features in oculopharyngeal muscular dystrophy (OPMD). Objective: Retroflexion of the head is a well known compensatory mechanism for ptosis, but generally retroflexion has a negative effect on swallowing. We hypothesised that severity of ptosis is related to degree of retroflexion and that this compensation is responsible for deteriorating dysphagia. Methods: Nine OPMD patients were examined in the conditions “head position adapted to ptosis' and “head position slightly flexed'. Ptosis was quantified by photogrammetry and retroflexion of the head by digital photographs. The severity of dysphagia was measured using visual analogue scales (VAS) and by calculating swallowing volumes and oropharyngeal swallow efficiency (OPSE) based on videofluoroscopy. Results: Statistical analyses show a significant relationship between ptosis and degree of retroflexion. The degree of retroflexion of the head correlated significantly with VAS scores and with the maximum swallowing volume. The slightly flexed head position significantly improved VAS scores as well as swallowing volumes and OPSE. Conclusion: In OPMD patients, ptosis significantly correlates with retroflexion of the head, which has a negative effect on swallowing. Subjective and objective reduction of swallowing problems was found when patients were instructed to eat and drink with a slightly flexed head position. | De Swart B.J.M. Van Der Sluijs B.M. Vos A.M.C. 王孝文 | 2006 | 世界核心医学期刊文摘(神经病学分册)2006，2，6： | 0 |
| 12 | 成年起病型强直性肌营养不良患者肌强直和弛缓型构音障碍 | De Swart B.J.M. Van Engelen B.G.M. Van De Kerkhof J.P.B.M. Maassen B.A.M. 高方 | 2005 | 世界核心医学期刊文摘(神经病学分册)2005，0，2： | 0 |
| 13 | 西德肉用牛的生产、测定和选育制度显示文摘西德的牛在全年或全年的大部分时间里都是进行集约化舍饲的,喂的是青贮饲料、干草和精饲料。以乳肉兼用品种为主。选种的重点是增加奶量和改进15—18个月的瘦公牛的肉质。西德有大量的活牛出口贸易,但是所需要的牛肉和小牛肉,34%靠进口。农场和牛群的规模以澳洲标准来衡量都比较小,因此需要集中进行性能和后裔测定。由于广泛采用了人工授精,使得经过精选的少量良种公牛的优良遗传物体得到了广泛传播。对西德两个州的选种和测定方案进行了比较。这些方案是按照良种公牛与高产母牛的计划配种进行的。在性能测定之后进行精液测定和后裔测定,后者指对种牛的女儿和儿子分别测定其繁殖、产奶、产肉能力。对于不加限制地使用人工授精的公牛。 | B.J.M.霍兰德 | 1980 | 世界农业1980，，7： | 0 |
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