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| 1 | Heteromeric and Homomeric Geranyl Diphosphate Synthases from Catharanthus roseus and Their Role in Monoterpene Indole Alkaloid Biosynthesis显示文摘Catharanthus roseus 是二很重要的 monoterpene 吲哚碱(MIA ) 的唯一的来源反癌症代理人:vinblastine 和长春新碱。MIA 拥有萜烯和分别地从 terpenoid 和 shikimate 小径导出的吲哚一半。Geranyl diphosphate (GPP ) ,入口点到萜烯一半的形成,由 GPP synthase (GPPS ) 是 isopentenyl diphosphate (IPP ) 和 dimethylallyl diphosphate (DMAPP ) 的冷凝作用的一个产品。这里,我们报导与顺序类似编码蛋白质到大子单元(CrGPPS.LSU ) 和 heteromeric GPPS,和 homomeric 的小子单元(CrGPPS.SSU ) 的三基因 GPPS。CrGPPS.LSU 是生产 GPP 和 geranyl geranyl diphosphate (GGPP ) 的 bifunctional 酶, CrGPPS.SSU 是不活跃的,而 CrGPPS 是形成 GPP 的 homomeric 酶。在 Escherichia coli 的两个子单元的合作表示与生产仅仅 GPP 的提高的活动导致了 heteromeric 酶。当 CrGPPS.LSU 和 CrGPPS 在更旧、更年轻的叶子显示出更高的表示时,分别地, CrGPPS.SSU 显示出一个增加的趋势并且逐渐地减少了。叶子的甲基 jasmonate (MeJA ) 处理显著地导致了仅仅 CrGPPS.SSU 的表示。而 CrGPPS 是 mitochondrial, GFP 本地化显示 CrGPPS.SSU 是 plastidial。在 C 的 AmGPPS.SSU 的短暂 overexpression。roseus 叶子导致了增加的 vindoline, vinblastine 和长春新碱的立即的 monomeric 先锋。尽管 C。roseus 有 heteromeric 和 homomeric GPPS 酶,我们的结果含有有为 MIA 生合成调整 GPP 流动的 CrGPPS.SSU 的仅仅 heteromeric GPPS 的参与。 | Avanish Rai Shachi S. Smita Anup Kumar Singh Karuna Shanker Dinesh A. Nagegowda | 2013 | Molecular Plant2013，6，5： | 20 |
| 2 | Experimental studies of water hammer in propellant feed system of reaction control system显示文摘Water hammer pressure transient produces large dynamic forces which can damage the pipes and other assemblies in the feed line of a reaction control system(RCS).It has led to the failure of pressure transducers monitoring the manifold pressure in the feed line of RCS.Therefore,water hammer studies have been carried out to understand its effect in feed line.Feedline system has been simplified to develop a mathematical model and experiments have been carried out at extensive levels.The mathematical model was developed considering pipe of uniform c/s and moving liquid-gas interface.The experimental studies have been done using water as working medium instead of actual propellant.The studies showed that rate of pressurization have a very critical role on the water hammer amplitude.Sensitivity studies have been also carried out to study the effect of density,friction and initial liquid column length on water hammer amplitude. | Avanish Kumar P.Satya Prasad M.Raghavendra Rao | 2018 | Propulsion and Power Research2018，7，1： | 3 |
| 3 | Simultaneous optimization of multiple quality characteristics in laser cutting of titanium alloy sheet显示文摘 | Arun Kumar Pandey Avanish Kumar Dubey | 2012 | Optics and Laser Technology2012，，6： | 2 |
| 4 | Next-Generation Intelligent MXene-Based Electrochemical Aptasensors for Point-of-Care Cancer Diagnostics显示文摘Delayed diagnosis of cancer using conventional diagnostic modalities needs to be addressed to reduce the mortality rate of cancer.Recently,2 D nanomaterial-enabled advanced biosensors have shown potential towards the early diagnosis of cancer.The high surface area,surface functional groups availability,and excellent electrical conductivity of MXene make it the 2 D material of choice for the fabrication of advanced electrochemical biosensors for disease diagnostics.MXene-enabled electrochemical aptasensors have shown great promise for the detection of cancer biomarkers with a femtomolar limit of detection.Additionally,the stability,ease of synthesis,good reproducibility,and high specificity offered by MXene-enabled aptasensors hold promise to be the mainstream diagnostic approach.In this review,the design and fabrication of MXene-based electrochemical aptasensors for the detection of cancer biomarkers have been discussed.Besides,various synthetic processes and useful properties of MXenes which can be tuned and optimized easily and efficiently to fabricate sensitive biosensors have been elucidated.Further,futuristic sensing applications along with challenges will be deliberated herein. | Arpana Parihar Ayushi Singhal Neeraj Kumar Raju Khan MohdAkram Khan Avanish KSrivastava | 2022 | Nano-Micro Letters2022，14，6： | 2 |
| 5 | Laser Beam Machining--A Review 显示文摘 | Avanish Kumar Dubey Vinod Yadava | 2008 | International Journal of Machine Tools and Manufacture2008，48，6： | 1 |
| 6 | Laser beam machining-a review显示文摘 | Avanish Kumar Dubey Vinod Yadava | 2008 | International Journal of Machine Tools and Manufacure2008，48，6： | 1 |
| 7 | Robust parameter design and multi-objective optimization of laser beam cutting for aluminium alloy sheet显示文摘 | Avanish Kumar Dubey Vinod Yadava | 2008 | The International Journal of Advanced Manufacturing Technology2008，38，34： | 1 |
| 8 | Nanobiocomposite platform based on polyaniline-iron oxide-carbon nanotubes for bacterial detection显示文摘 | Renu Singh Rachna Verma G. Sumana Avanish Kumar Srivastava Seema Sood Rajinder K. Gupta B.D. Malhotra | 2012 | Bioelectrochemistry2012，，： | 1 |
| 9 | A Modified Method for Solving the Unbalanced Assignment Problems 显示文摘 | KUMAR AVANISH | 2006 | Applied Mathematics and Computat ion2006，，176： | 1 |
| 10 | Laser beam machining- A review显示文摘 | Avanish Kumar Dubey Vinod Yadava | 2008 | International Journal of Machine Tools & Manufacture2008，48，： | 1 |
| 11 | Laser beam machining—A review显示文摘 | Avanish Kumar Dubey Vinod Yadava | 2007 | International Journal of Machine Tools and Manufacture2007，，6： | 1 |
| 12 | Multiple quality optimization in laser cutting of difficuh-to-laser-cut material using grey-fuzzy methodology 显示文摘 | Arun Kumar Pandey & Avanish Kumar Dubey | 2013 | Int J Adv Manuf Technol2013，65，14： | 1 |
| 13 | A eacile and novel synthesis of Ag-raphene-based nanocomposites显示文摘 | Renu Pasricha Shweta Gupta and Avanish Kumar Srivastava | 2009 | Small2009，5，20： | 1 |
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