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| 1 | Automation of immunohistochemical evaluation in breast cancer using image analysis显示文摘AIM:To automate breast cancer diagnosis and to study the inter-observer and intra-observer variations in the manual evaluations.METHODS:Breast tissue specimens from sixty cases were stained separately for estrogen receptor(ER),progesterone receptor(PR)and human epidermal growth factor receptor-2(HER-2/neu).All cases were assessed by manual grading as well as image analysis.The manual grading was performed by an experienced expert pathologist.To study inter-observer and intra-observer variations,we obtained readings from another pathologist as the second observer from a different laboratory who has a little less experience than the first observer.We also took a second reading from the second observer to study intra-observer variations.Image analysis was carried out using in-house developed software(TissueQuant).A comparison of the results from image analysis and manual scoring of ER,PR and HER-2/neu was also carried out.RESULTS:The performance of the automated analysis in the case of ER,PR and HER-2/neu expressions was compared with the manual evaluations.The performance of the automated system was found to correlate well with the manual evaluations.The inter-observer variations were measured using Spearman correlation coefficient r and 95%confidence interval.In the case of ER expression,Spearman correlation r=0.53,in the case of PR expression,r=0.63,and in the case of HER-2/neu expression,r=0.68.Similarly,intra-observer variations were also measured.In the case of ER,PR and HER-2/neu expressions,r=0.46,0.66 and 0.70,respectively.CONCLUSION:The automation of breast cancer diagnosis from immunohistochemically stained specimens is very useful for providing objective and repeatable evaluations. | Keerthana Prasad Avani Tiwari Sandhya Ilanthodi Gopalakrishna Prabhu Muktha Pai | 2011 | World Journal of Clinical Oncology2011，2，4： | 3 |
| 2 | Effect of E-Learning on Public Health and Environment During COVID-19 Lockdown显示文摘E-learning is the most promising venture in the entire world. During the COVID-19 lockdown, e-learning is successfully providing potential information to the students and researchers. In developing nations like India, with limited resources, e-learning tools and platforms provide a chance to make education available to middle and low income households. This paper gives insights about three different online services, namely Google Classroom,Zoom, and Microsoft Teams being used by three different educational institutions. We aim to analyze the efficiency and acceptability of e-learning tools among Indian students during the COVID-19 lockdown. The paper also aims to evaluate the impact of e-learning on the environment and public health during COVID-19 lockdown. It is found that e-learning has potential to reduce carbon emissions, which has beneficial impact on the environment. However, the mental health is impacted as e-learning may lead to self-isolation and reduction in academic achievements that may lead to anxiety and mental depression. Due to usage of electronic devices for learning, the eyes and neck muscles may be put in strain, having deleterious effects on physical health. | Avani Agarwal Sahil Sharma Vijay Kumar Manjit Kaur | 2021 | Big Data Mining and Analytics2021，4，2： | 2 |
| 3 | Arsenic induced free radical toxicity in brain of mice 显示文摘 | Rao MN Avani G | 2004 | Indian J Exp Biol2004，42，5： | 1 |
| 4 | Enzymatic Natural Dyeing of Cotton and Silk Fabrics Without Met- al Mordants显示文摘 | PADMA S VANKAR RAKHI S AVANI V | 2007 | Science Direct2007，15，： | 1 |
| 5 | In vitro genotoxicity assays to evaluate the role ofvitamin A on arsenic in human lymphocytes显示文摘 | Avani G Rao MV | 2009 | Ecotoxicol EnvironSaf2009，72，2： | 1 |
| 6 | Exploring the role of Th1 cytokines:interleukin-17 and interleukin-18 in periodontal health and disease显示文摘 | Avani R Pradeep T Parag H | 2009 | J Oral Sci2009，2，： | 1 |
| 7 | Hydrotalcite-type anionic clays:preparation,properties and applications显示文摘 | AVANI F RIFIR F VACCARI A | 1991 | Catalysis Today1991，2，2： | 1 |
| 8 | Arsenic induced free radical toxicity in brain of mice显示文摘 | RaoMV Avani G | 2004 | Indian J Exp Biol2004，42，： | 1 |
| 9 | The Promise Of Data Grouping In Large Scale Storage Systems显示文摘 | Wildani Avani | 2013 | Computer Science2013，36，8： | 1 |
| 10 | Fabric structure and mold curvature effects on preform permeability and mold filling in the RTM process,Part Ⅱ:Predictions and comparisons with experiments显示文摘 | Bickerton S Sozer E M Simácek P Avani S G | 2000 | Composites Part A2000，31，： | 1 |
| 11 | Purification, characterization and comparison of phycoerythrins from three different marine cyanobacterial cultures显示文摘 | Asha Parmar Niraj Kumar Singh Avani Kaushal Sagar Sonawala Datta Madamwar | 2010 | Bioresource Technology2010，，： | 1 |
| 12 | Expression of microRNA-30c and its target genes in human osteoblastic cells by nano-bioglass ceramic- treatment 显示文摘 | Moorthi A Vimalraj S Avani C | 2013 | Int J Biol Macromo12013，56，： | 1 |
| 13 | Uptake of water-and energy-conservation devices in the home显示文摘 | Avani Babooram and Matt Hurst | 2010 | Canadian SocialTrends2010，2010，91： | 1 |
| 14 | Formulation de- sign and optimization of mouth dissolve tablets of nimesulide using vacuum drying technique 显示文摘 | MUKESH G MADHABHAI P AVANI A | 2004 | AAPS Pharm Sci Tech2004，5，3： | 1 |
| 15 | Enzymatic natural dyeing of cotton and silk fabrics without metal mordants显示文摘 | Padma S.Vankar Rakhi Shanker Avani Verma | | 0，，15： | 1 |
| 16 | Dry eye syndrome: A rising occupational hazard in tropical countries显示文摘 | Kavita Bhatnagar Avani Sapovadia Divya Gupta Pooja Kumar Hemal Jasani | 2014 | Medical Journal of Dr DY Patil University2014，，1： | 1 |
| 17 | Arsenic Induced Free Radical Toxicity in Brain of Mice 显示文摘 | Rao MV Avani G | 2004 | Indian J Exp Biol2004，42，5： | 1 |
| 18 | Arsenic induced free radical toxicity in brain of mice显示文摘 | Rao MV Avani G | 2004 | Indian Journal of Experimental Biology2004，42，： | 1 |
| 19 | Virtual world teaching, experiential learning, and assessment: An interdisciplinary communication course in Second Life显示文摘 | Leslie Jarmon Tomoko Traphagan Michael Mayrath Avani Trivedi | 2009 | Computers & Education2009，，1： | 1 |
| 20 | Arsenic induced free radical toxicity in brain of mice显示文摘 | Rao MV Avani G | | 0，，： | 1 |
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