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| 1 | 骨头的 Immunophenotype 和区别能力从 CBA/Ca, ICR 和 Balb/c 的导出髓的间充质的干细胞老鼠显示文摘 AIM:To assess the capacity to isolate and expand mesenchymal stem cells(MSC)from bone marrow of CBA/Ca,ICR and Balb/c mice. METHODS:Bone marrow of tibia and femur were flushed,cultured and maintained in supplemented Dulbecco’s modified Eagle’s medium.MSC immunophenotype of cultures were tracked along increasing passages for positivity to CD106,Sca-1 and CD44 and negativity to CD45,CD11b and MHC classⅡ.Differentiation capacity of MSC towards osteogenic and adipo-genic lineages were also assessed. RESULTS:MSC were successfully cultured from bone marrow of all 3 strains,albeit differences in the temporal expression of certain surface antigens.Their differentiation into osteocytes and adipocytes were also observed. MSC from all 3 mouse strains demonstrated a shift from a haematopoietic phenotype(CD106-CD45+CD11b+Sca-1low)to typical MSC phenotype(CD106+CD45-CD11b-Sca-1high)with increasing passages. CONCLUSION:Information garnered assists us in the decision of selecting a mouse strain to generate MSC from for downstream experimentation. | Yin Yin Ooi Zul'atfi Rahmat Shinsmon Jose Rajesh Ramasamy Sharmili Vidyadaran | 2013 | World Journal of Stem Cells2013，5，1： | 3 |
| 2 | Repeated occurrence of palaeo-wildfires during deposition of the Bahariya Formation(early Cenomanian) of Egypt显示文摘The Upper Cretaceous(early Cenomanian)Bahariya Formation of Egypt has an outstanding reputation for its wealth of vertebrate remains,including a variety of iconic dinosaurs,like the carnivorous Spinosaurus and Carcharodontosaurus,as well as the herbivorous Aegyptosaurus and Paralititan.Besides these dinosaur fossils,the Bahariya Formation yielded also a wealth of invertebrate and plant remains,but even today many aspects concerning the continental palaeoenvironments reflected in these deposits(including the occurrence of palaeo-wildfires)have not been studied in detail.So far six distinct macro-charcoal bearing levels could be identified within the type section of the Bahariya Formation at Gabal El Dist profile,one of the most prolific outcrops of this formation in terms of fossil occurrence located in the north of the Bahariya Oasis,Western Desert,Egypt.Most of the charcoal investigated by means of SEM originates from ferns,pointing to a considerable proportion of this plant group within the palaeo-ecosystems that experienced fires.Gymnosperms and(putative)angiosperms have less frequently been identified.The collected data present evidence that the landscapes at the northern shores of Gondwana repeatedly experienced palaeo-wildfires,adding extra proof to previous statements that the Late Cretaceous was a fiery world on a global scale. | Haytham El Atfy Tarek Anan Andre Jasper Dieter Uhl | 2019 | Journal of Palaeogeography2019，8，4： | 2 |
| 3 | The clinical significance of OPG/sRANKL ratio in thalassemia patients suffering from osteopenia orosteoporosis in Egyptian patients 显示文摘 | Salah H Atfy M Fathy A | 2010 | Immunol Invest2010，39，8： | 1 |
| 4 | Activation of mitogen-activated protein kinase is in regulation of bone morphogenetic protein-2-induced osteoblast differentiation in pluripotent C2C12 cells显示文摘 | Gallea S Lallemand F Atfi A | 2001 | Bone2001，28，5： | 1 |
| 5 | Source rock potential and paleoenvironment of the Miocene Rudeis and Kareem formation,Gulf of Suez,Egypt:An integrated palynofacies and organic geochemical approach显示文摘 | Haytham Ei Atfy Rainer Brocke Dieter Ghl | 2014 | International Journal of Coal Geology2014，131，： | 1 |
| 6 | Role of urokinase plasminogen activator receptor (CD87) as a prognostic marker in acute myeloid leukemia显示文摘 | Atfy M Eissa M Hossam E | | 0，，03： | 1 |
| 7 | The oncoprotein e-ski functions as a direct antagonist of the transtorming growth factor-{heta} type I receptor 显示文摘 | Ferrand N Atfi A Prunier C | 2010 | Cancer Res2010，70，21： | 1 |
| 8 | Role of urokinase plas-minogen activator receptor(CD87)as a prognostic marker in acute mye-loid leukemia显示文摘 | Maha Atfy Mohamad Eissa Hossam E | 2012 | Med Oncol2012，29，3： | 1 |
| 9 | Activation of mitogen-activated protein kinase cascades is involved in regulation of bone morphogenetic protein-2-induced osteoblast differentiation in pluripotent C2 C12 cells显示文摘 | Gallea S F Lallemand A Atfi | 2001 | Bone2001，28，5： | 1 |
| 10 | p53 brings a new twist to the Smad signaling net- work 显示文摘 | Atfi A Baron R | 2008 | Science Signal2008，1，26： | 1 |
| 11 | The oncoprotein c-Ski functions as a direct antagonist of the transforming growth factor-β type I receptor显示文摘 | Ferrand N Atfi A Prunier C | 2010 | Cancer Res2010，70，21： | 1 |
| 12 | Induction of apoptosis by DPC4, a transcription factor regulated by transforming growth factor-β through stress-activated protein kinase/c-Jun N-terminal kinase(SAPK/JNK) signaling pathway显示文摘 | Atfi A Buisine M Mazars A Gespach C | 1997 | J Biol Chem1997，272，24： | 1 |
| 13 | Evidence for a role of MSK1 in transforming growth factor-β-mediated responses through p38α and Smad signaling pathway显示文摘 | Abecassis L Rogier E Vazquea A Atfi A Bourgeade MF | 2004 | J Biol Chem2004，279，30： | 1 |
| 14 | 显示文摘 | Djelloul S Chastre E | 1997 | J Biol Chem1997，272，3： | 1 |
| 15 | Activation of mitogen-activated protein kinase cascades is involved in regulation of bone morphogenetic protein-2-induced osteoblast differentiation in pluripotent C2C12 cells 显示文摘 | Gallea S Lallemand F Atfi A | 2001 | Bone2001，28，5： | 1 |
| 16 | Evidence for a role of Rho-like GTPases and stress-activated protein kinase/c-Jun N-terminal kinase(SAPK/JNK) in transforming growth factor beta-mediated signaling显示文摘 | Atfi A Djelloul S Chastre E | 1997 | J Biol Chem1997，272，3： | 1 |
| 17 | Bone marrow-derived mesenchymal stem cells modulate BV2 microglia responses to lipopolysaccharide显示文摘 | Yin Yin Ooi Rajesh Ramasamy Zul’atfi Rahmat Hemavathy Subramaiam Shi Wei Tan Maha Abdullah Daud Ahmad Israf Sharmili Vidyadaran | 2010 | International Immunopharmacology2010，，12： | 1 |
| 18 | Role of urokinase plasminogen activator receptor (CD87) as a prognostic marker in acute myeloid leukemia显示文摘 | Maha Atfy Mohamad Eissa Hossam Salah Deena El Shabrawy | 2012 | Medical Oncology2012，，3： | 1 |
| 19 | Impact of CD4+CD25high regulatory T-cells and FoxP3 expression in the peripheral blood of patients with systemic lupus erythematosus 显示文摘 | Atfy M Amr GE Elnaggar AM | 2009 | Egypt J Immunol2009，16，1： | 1 |
| 20 | Activation of mitogen-actirated protein kinase cascades is involved in regulation of bone morphogenetic protein-2-induced osteoblast differentiation in pluripotent C2C12 cells 显示文摘 | Gallea S Lallemand F Atfi A | 2001 | Bone2001，28，5： | 1 |
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