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| 1 | Surgery in biliary lithiasis: from the traditional “open” approach to laparoscopy and the“rendezvous” technique显示文摘BACKGROUND:According to the current literature, biliary lithiasis is a worldwide-diffused condition that affects almost 20% of the general population. The rate of common bile duct stones(CBDS) in patients with symptomatic cholelithiasis is estimated to be 10% to 33%, depending on patient's age.Compared to stones in the gallbladder, the natural history of secondary CBDS is still not completely understood. It is not clear whether an asymptomatic choledocholithiasis requires treatment or not. For many years, open cholecystectomy with choledochotomy and/or surgical sphincterotomy and cleaning of the bile duct were the gold standard to treat both pathologies. Development of both endoscopic retrograde cholangiopancreatography(ERCP) and laparoscopic surgery,together with improvements in diagnostic procedures, influenced new approaches to the management of CBDS in association with gallstones.DATA SOURCES:We decided to systematically review the literature in order to identify all the current therapeutic options for CBDS. A systematic literature search was performed independently by two authors using Pub Med, EMBASE, Scopus and the Cochrane Library Central.RESULTS:The therapeutic approach nowadays varies greatly according to the availability of experience and expertise in each center, and includes open or laparoscopic common bile duct exploration, various combinations of laparoscopic cholecystectomy and ERCP and combined laparoendoscopic rendezvous.CONCLUSIONS:Although ERCP followed by laparoscopic cholecystectomy is currently preferred in the majority of hospitals worldwide, the optimal treatment for concomitant gallstones and CBDS is still under debate, and greatly varies among different centers. | Giuseppe Tarantino Paolo Magistri Roberto Ballarin Giacomo Assirati Antonio Di Cataldo Fabrizio Di Benedetto | 2017 | Hepatobiliary & Pancreatic Diseases International2017，16，6： | 18 |
| 2 | Radiofrequency ablation vs surgical resection in elderly patients with hepatocellular carcinoma in Milan criteria显示文摘BACKGROUND Surgical resection and radiofrequency ablation(RFA)represent two possible strategy in treatment of hepatocellular carcinoma(HCC)in Milan criteria.AIM To evaluate short-and long-term outcome in elderly patients(>70 years)with HCC in Milan criteria,which underwent liver resection(LR)or RFA.METHODS The study included 594 patients with HCC in Milan criteria(429 in LR group and 165 in RFA group)managed in 10 European centers.Statistical analysis was performed using the Kaplan-Meier method before and after propensity score matching(PSM)and Cox regression.RESULTS After PSM,we compared 136 patients in the LR group with 136 patients in the RFA group.Overall survival at 1,3,and 5 years was 91%,80%,and 76%in the LR group and 97%,67%,and 41%in the RFA group respectively(P=0.001).Diseasefree survival at 1,3,and 5 years was 84%,60%and 44%for the LR group,and 63%,36%,and 25%for the RFA group(P=0.001).Postoperative Clavien-Dindo IIIIV complications were lower in the RFA group(1%vs 11%,P=0.001)in association with a shorter length of stay(2 d vs 7 d,P=0.001).In multivariate analysis,Model for End-stage Liver Disease(MELD)score(>10)[odds ratio(OR)=1.89],increased value of international normalized ratio(>1.3)(OR=1.60),treatment with radiofrequency(OR=1.46),and multiple nodules(OR=1.19)were independent predictors of a poor overall survival while a high MELD score(>10)(OR=1.51)and radiofrequency(OR=1.37)were independent factors associated with a higher recurrence rate.CONCLUSION Despite a longer length of stay and a higher rate of severe postoperative complications,surgery provided better results in long-term oncological outcomes as compared to ablation in elderly patients(>70 years)with HCC in Milan criteria. | Maria Conticchio Riccardo Inchingolo Antonella Delvecchio Letizia Laera Francesca Ratti Maximiliano Gelli Ferdinando Anelli Alexis Laurent Giulio Vitali Paolo Magistri Giacomo Assirati Emanuele Felli Taiga Wakabayashi Patrick Pessaux Tullio Piardi Fabrizio di Benedetto Nicola de'Angelis Javier Briceño AntonioRampoldi RenèAdam Daniel Cherqui Luca Antonio Aldrighetti Riccardo Memeo | 2021 | World Journal of Gastroenterology2021，27，18： | 4 |
| 3 | Parasagiattal meningomas: follow-up review显示文摘 | Colli BO Carlotti CG Jr Assirati JA Jr | 2013 | Surg Neurol2013，66，3： | 1 |
| 4 | Parasagiattal meningomas:follow-up review 显示文摘 | Colli BO Carlotti CG Jr Assirati JA Jr | 2006 | Surg Neurol2006，66，3： | 1 |
| 5 | Parasagittal meningiomas: follow-up review显示文摘 | Colli BO Carlotti CG Jr Assirati JA Jr | 2006 | Surg Neurol2006，66，3： | 1 |
| 6 | On the prognostic value of ictal EEG patterns in temporal lobe epilepsy surgery:a cohort study显示文摘 | Monnerat BZ Velasco TR Assirati JA Jr | 2013 | Seizure2013，22，4： | 1 |
| 7 | Glutamate NMDA Receptor Subunit R1 and GAD mRNA Expression in Human Temporal Lobe Epilepsy显示文摘 | Luciano Neder Valeria Valente Carlos G. Carlotti Jo?o P. Leite Jo?o A. Assirati Maria L. Pa?ó-Larson Jorge E. Moreira | 2002 | Cellular and Molecular Neurobiology (-)2002，，56： | 1 |
| 8 | Plasticity,synaptic strength,and epilepsy:what can we learnfrom ultrastructural data显示文摘 | Leite JP Neder L Arisi GM Carlotti Jr CG Assirati JA MoreiraJE | 2005 | Epilepsia2005，46，5： | 1 |
| 9 | Tentorial meningiomas: follow-up review显示文摘 | Benedicto Oscar Colli Jo?o Alberto Assirati Danilo Jorge Pinho Deriggi Luciano Neder Antonio Carlos dos Santos Carlos Gilberto Carlotti | 2008 | Neurosurgical Review2008，，4： | 1 |
| 10 | Parasagittal meningiomas:follow-up review显示文摘 | Colli BO Carlotti CG Jr Assirati JA | | 0，，3： | 1 |
| 11 | Parasagittal meningiomas: follow-up review显示文摘 | Colli BO Carlotti CG Jr Assirati JA Jr | 2006 | Surg Neurol2006，3，： | 1 |
| 12 | Olfactory groove men- ingioma: surgical techniques and follow-up review 显示文摘 | CoUi BO Cadotti CG Jr Assirati JA Jr | 2007 | Arq Neurop- siquiatr2007，65，3： | 1 |
| 13 | Parasagittal meningiomas: follow-up review显示文摘 | COLLI BO CARLOTFI CG ASSIRATI JA | 2006 | Surg Neurol2006，66，3： | 1 |
| 14 | Neurotrophins in mesial temporal lobe epilepsy with and without psychiatric comorbidities显示文摘 | Kandratavicius L Monteiro MR Assirati JA Jr | 2013 | J Neuropathol Exp Neurol2013，72，11： | 1 |
| 15 | Performing edge detection by difference of Gaussians using q-Gaussian kernels显示文摘 | Assirati L Da S | 2013 | Computer Science2013，20，11： | 1 |
| 16 | Tentorial meningiomas: follow-up review显示文摘 | Colli BO Assirati JA Deriggi D J | 2008 | Neurosurg Review2008，31，4： | 1 |
| 17 | Parasagittal meningiomas: follow-up review 显示文摘 | Colli BO Carlotti Jr CG Assirati JA | 2006 | Snrs Neuro12006，66，3： | 1 |
| 18 | Distinct increased metabotropic glutamate receptor type 5 (mGluR5) in temporal lobe epilepsy with and without hippocampal sclerosis显示文摘 | Ludmyla Kandratavicius Pedro Rosa‐Neto Mariana Raquel Monteiro Marie‐Christine Guiot Joao Alberto Assirati Carlos Gilberto Carlotti Eliane Kobayashi Joao Pereira Leite | 2013 | Hippocampus2013，，12： | 1 |
| 19 | Liver resection vs radiofrequency ablation in single hepatocellular carcinoma of posterosuperior segments in elderly patients显示文摘BACKGROUND Liver resection and radiofrequency ablation are considered curative options for hepatocellular carcinoma.The choice between these techniques is still controversial especially in cases of hepatocellular carcinoma affecting posterosuperior segments in elderly patients.AIM To compare post-operative outcomes between liver resection and radiofrequency ablation in elderly with single hepatocellular carcinoma located in posterosuperior segments.METHODS A retrospective multicentric study was performed enrolling 77 patients age≥70-years-old with single hepatocellular carcinoma(≤30 mm),located in posterosuperior segments(4a,7,8).Patients were divided into liver resection and radiofrequency ablation groups and preoperative,peri-operative and long-term outcomes were retrospectively analyzed and compared using a 1:1 propensity score matching.RESULTS After propensity score matching,twenty-six patients were included in each group.Operative time and overall postoperative complications were higher in the resection group compared to the ablation group(165 min vs 20 min,P<0.01;54%vs 19%P=0.02 respectively).A median hospital stay was significantly longer in the resection group than in the ablation group(7.5 d vs 3 d,P<0.01).Ninety-day mortality was comparable between the two groups.There were no significant differences between resection and ablation group in terms of overall survival and disease free survival at 1,3,and 5 years.CONCLUSION Radiofrequency ablation in posterosuperior segments in elderly is safe and feasible and ensures a short hospital stay,better quality of life and does not modify the overall and disease-free survival. | Antonella Delvecchio Riccardo Inchingolo Rita Laforgia Francesca Ratti Maximiliano Gelli Massimiliano Ferdinando Anelli Alexis Laurent Giulio Vitali Paolo Magistri Giacomo Assirati Emanuele Felli Taiga Wakabayashi Patrick Pessaux Tullio Piardi Fabrizio di Benedetto Nicola de'Angelis Javier Briceño Antonio Rampoldi RenèAdam Daniel Cherqui Luca Antonio Aldrighetti Riccardo Memeo | 2021 | World Journal of Gastrointestinal Surgery2021，13，12： | 1 |
| 20 | Results of microsurgical treatment of paraclinoid carotid aneurysms显示文摘 | Colli BO Carlotti CG Jr Assirati JA Jr | 2013 | Neurosurg Rev2013，36，1： | 1 |
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