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| 1 | Abdominal applications of diffusion-weighted magnetic resonance imaging: Where do we stand?显示文摘Diffusion-weighted imaging (DWI) is one of the magnetic resonance imaging (MRI) sequences providing qualitative as well as quantitative information at a cellular level. It has been widely used for various applications in the central nervous system. Over the past decade, various extracranial applications of DWI have been increasingly explored, as it may detect changes even before signal alterations or morphological abnormalities become apparent on other pulse sequences. Initial results from abdominal MRI applications are promising, particularly in oncological settings and for the detection of abscesses. The purpose of this article is to describe the clinically relevant basic concepts of DWI, techniques to perform abdominal DWI, its analysis and applications in abdominal visceral MR imaging, in addition to a brief overview of whole body DWI MRI. | Ajaykumar C Morani Khaled M Elsayes Peter S Liu William J Weadock Janio Szklaruk Jonathan Russell Dillman Asra Khan Thomas L Chenevert Hero K Hussain | 2013 | World Journal of Radiology2013，5，3： | 12 |
| 2 | Sources and Ecological Risks of Heavy Metals in Soils Under Different Land Uses in Bangladesh显示文摘Soil heavy metal pollution, influenced by both natural and anthropogenic factors, significantly reduces environmental quality. In this study, Cr, Ni, Cu, As, Cd, and Pb in eight different land-use soils from Patuakhali District in Bangladesh were assessed. Concentrations of Cr, Ni, Cu, As, Cd, and Pb in soils were 1-87, 5-271, 4-181, 0-80, 0.2-24.0, and 5-276 mg kg-1, respectively, measured using an inductively coupled plasma-mass spectrometer. The enrichment factor, pollution load index (PLI), and contamination factor (CJ) of metal i were used to assess the ecological risk posed by metals in soils. The PLI ranged from 0.78 to 2.66, indicating baseline levels to progressive deterioration of soil due to metal contamination. However, C;of Cd ranged from 1.8 to 12.0, which showed that the studied soils were strongly impacted by Cd. Considering the severity of the potential ecological risk of a single metal, the descending order was Cd > As > Pb > Cu > Ni > Cr. Soils under all land uses showed moderate to very high potential ecological risk. | Mohammad Saiful ISLAM Mohammad Kawser AHMED Mohammad Habibullah AL-MAMUN Shah Mohammad Asraful ISLAM | 2019 | Pedosphere2019，29，5： | 5 |
| 3 | Malnutrition and liver disease in a developing country显示文摘Malnutrition is a highly prevalent and under recognized condition in developing countries of South Asia.The presence of malnutrition causes a severe impact on patients with liver cirrhosis.The etiology of cirrhosis differs in the South Asian region compared to the West,with hepatitis B and C still being the leading causes and the prevalence of nonalcoholic fatty liver disease increasing over time.Comorbid malnutrition worsens outcomes for cirrhosis patients.Urgent attention to address malnutrition is needed to improve patient outcomes.The etiology and pathophysiology of malnutrition in liver diseases is multifactorial,as reduction in liver function affects both macronutrients and micronutrients.A need for nutritional status assessment for liver disease patients exists in all parts of the world.There are many widely studied tools in use to perform a thorough nutritional assessment,of which some tools are low cost and do not require extensive training.These tools can be studied and evaluated for use in the resource limited setting of a country like Pakistan.Treatment guidelines for proper nutrition maintenance in chronic liver disease exist for all parts of the world,but the knowledge and practice of nutritional counseling in Pakistan is poor,both amongst patients and physicians.Emphasis on assessment for nutritional status at the initial visit with recording of vital signs is needed.Simultaneously,treating physicians need to be made aware of the misconceptions surrounding nutritional restrictions in cirrhosis so that patient education is done correctly based on proper scientific evidence. | Asra tus Saleha Siddiqui Om Parkash Syeda Amrah Hashmi | 2021 | World Journal of Gastroenterology2021，27，30： | 3 |
| 4 | scFv Antibody: Principles and Clinical Application显示文摘 | Zuhaida Asra Ahmad Swee Keong Yeap Abdul Manaf Ali Wan Yong Ho Noorjahan Banu Mohamed Alitheen Muhajir Hamid T. Nakayama | 2012 | Clinical and Developmental Immunology2012，，： | 2 |
| 5 | Comparison of half-molar sodium lactate and mannitol to treat brain edema in severe traumatic brain injury:A systematic review显示文摘Purpose:Hypertonic fluids such as mannitol and half-molar sodium lactate are given to treat intracranial hypertension in patients with severe traumatic brain injury(TBI).In this study,sodium lactate was compared to mannitol in patients with TBI to investigate the efficacy in reducing intracranial pressure(ICP).Methods:This study was a systematic review with literature research on articles published in any year in the databases of PubMed,ScienceDirect,Asian Journal of Neurosurgery,and Cochrane Central Register of Controlled Trials.The keywords were'half-molar sodium lactate','mannitol','cerebral edema or brain swelling',and'severe traumatic brain injury'.The inclusion criteria were(1)studies published in English,(2)randomized control trials or retrospective/prospective studies on TBI patients,and(3)therapies including half-molar sodium lactate and mannitol and(4)sufficient data such as mean difference(MD)and risk ratio(RR).Data analysis was conducted using Review Manager 5.3.Results:From 1499 studies,a total of 8 studies were eligible.Mannitol group reduced ICP of 0.65 times(MD 0.65;p=0.64)and improved cerebral perfusion pressure of 0.61 times(MD 0.61;p=0.88),better than the half-molar group of sodium lactate.But the half-molar group of sodium lactate maintained the mean arterial pressure level of 0.86 times,better than the mannitol group(MD 0.86;p=0.09).Conclusion:Half-molar sodium lactate is as effective as mannitol in reducing ICP in the early phase of brain injury,superior over mannitol in an extended period.It is able to prevent intracranial hypertension and give better brain tissue perfusion as well as more stable hemodynamics.Blood osmolarity is a concern as it increases serum sodium. | Abdul Hafid Bajamal Tedy Apriawan I.G.M.Aswin R.Ranuh Franco Servadei Muhammad Faris Asra Al Fauzi | 2021 | Chinese Journal of Traumatology2021，24，6： | 2 |
| 6 | Revisiting growth and poverty reduction in Indonesia:what do subnational data show 显示文摘 | Balisacan A M Pernia E M Asra A | 2002 | Economics and Research2002，25，7： | 1 |
| 7 | Human survivin is negatively regulated by wild-type p53 and participates in p53-dependent apoptotic pathway显示文摘 | Asra M Marnie M Tish NH | 2002 | Oncogene2002，21，17： | 1 |
| 8 | Prevalence of Neuroendocrine Dysfunction in Patients Recovering from Traumatic Brain Injury显示文摘 | Steven A.Lieberman Asra L.Oberoi Charles R.Gilkison | | 0，，06： | 1 |
| 9 | Abdominal applications of diffusion-weighted magnetic resonance imaging: Where do we stand?显示文摘 | Ajaykumar C Morani Khaled M Elsayes Peter S Liu William J Weadock Janio Szklaruk Jonathan Russell Dillman Asra Khan Thomas L Chenevert Hero K Hussain | | World Journal of Radiology0，，： | 1 |
| 10 | Characterization of flocculating agent from the self-flocculating microalga Scenedesmus obliquus AS-6-1 for efficient biomass harvest显示文摘 | Suo-Lian Guo Xin-Qing Zhao Chun Wan Zih-You Huang Yu-Liang Yang Md. Asraful Alam Shih-Hsin Ho Feng-Wu Bai Jo-Shu Chang | 2013 | Bioresource Technology2013，，： | 1 |
| 11 | Isolation of a novel gene encoding a 3,5,6-trich-loro-2-pyridinol degrading enzyme from a cow rumen mctagenomic library显示文摘 | MATH R K ASRAFUL ISLAM S M CHO K M ct al | 2010 | Biodcgradation2010，21，4： | 1 |
| 12 | Novel multiplex PCR for the detection of lactic acid bacteria during Kimchi fermentation显示文摘 | Cho K M MAth R K Asraful Islam S M | 2009 | Molecular and Cellu- lar Probes2009，23，： | 1 |
| 13 | Effect of plant age on endophytic bacterial diversity of Balloon Flower(Platycodon Grandiflorum)root and their antimicrobial activities显示文摘 | Shan M Asraful I Renukaradhya K | 2010 | Current Microbiol2010，61，： | 1 |
| 14 | Novel multiplex PCR for the detection of lactic acid bacteria during kimchi fermentation显示文摘 | Cho K M Math R K Asraful Islam S M | 2009 | Molecular and Cellular Probes2009，23，2： | 1 |
| 15 | Glinus lotoides ethanolic extract alleviates LPS-induced anxiety and depression-like behavior by modulating antioxidant and inflammatory biomarkers in rats显示文摘Objective:To explore the protective role of Glinus lotoides ethanolic extract in a depression model through modulating oxidant/antioxidant enzyme system and inflammatory status.Methods:Phytochemical constituents of Glinus lotoides ethanolic extract were evaluated qualitatively and quantitatively along with HPLC.Rats were divided into six groups.The normal control and the intoxicated groups received normal saline,and the standard group received imipramine,while the remaining groups received 100,300,and 500 mg/kg Glinus lotoides ethanolic extract.All groups received treatments for 14 d.Lipopolysaccharides(LPS)were then administered i.p.(0.83 mg/kg)to all groups except the normal control group.After 24 h,anxiety and depression-like behaviors were evaluated by performing behavioral analysis(open field,tail suspension,forced swim,sucrose preference test),and determining total oxidant status,total antioxidant capacity,catalase,and biochemical parameters[malondialdehyde,glutathione,superoxide dismutase,tumor necrosis factor(TNF)-alpha and interleukin(IL)-6].Results:Phytochemical studies confirmed the presence of phenols and flavonoids and HPLC analysis showed the presence of gallic acid,quercetin,chlorogenic,and caffeic acid.Total oxidant status was significantly decreased,while total antioxidant capacity was significantly increased in the Glinus lotoides ethanolic extract treated groups.Moreover,Glinus lotoides ethanolic extract diminished malondialdehyde,IL-6,and TNF-alpha levels,while increasing superoxide dismutase,catalase,and glutathione activities.Conclusions:Glinus lotoides ethanolic crude extract shows significant antidepressant activity by modulating oxidative and biochemical parameters that supports its folkloric use in traditional systems of medicine. | Ambreen Mehmood Awan Wafa Majeed Faraza Javed Bilal Aslam Asra Iftikhar Hafiza Arooj Kanwal Sobia Fiaz | 2022 | Asian Pacific Journal of Tropical Biomedicine2022，12，2： | 1 |
| 16 | Chronic low back pain and dis- ability among nurses:a cross seetional study from Bam,Iran显示文摘 | Laleh S Asra N Pourhaji F | 2016 | Int J Aearol Musculoskeletal Pain Prevention2016，1，1： | 1 |
| 17 | In silico identification and characterization of common epitope-based peptide vaccine for Nipah and Hendra viruses显示文摘Objective: To explore a common B-and T-cell epitope-based vaccine that can elicit an immune response against encephalitis causing genus Henipaviruses, Hendra virus(He V) and Nipah virus(Ni V). Methods: Membrane proteins F, G and M of He V and Ni V were retrieved from the protein database and subjected to different bioinformatics tools to predict antigenic B-cell epitopes. Best B-cell epitopes were then analyzed to predict their T-cell antigenic potentiality. Antigenic B-and T-cell epitopes that shared maximum identity with He V and Ni V were selected. Stability of the selected epitopes was predicted. Finally, the selected epitopes were subjected to molecular docking simulation with HLA-DR to confirm their antigenic potentiality in silico. Results: One epitope from G proteins, one from M proteins and none from F proteins were selected based on their antigenic potentiality. The epitope from the G proteins was stable whereas that from M was unstable. The M-epitope was made stable by adding flanking dipeptides. The 15-mer G-epitope(VDPLRVQWRNNSVIS) showed at least 66% identity with all Ni V and He V G protein sequences, while the 15-mer M-epitope(GKLEFRRNNAIAFKG) with the dipeptide flanking residues showed 73% identity with all Ni V and He V M protein sequences available in the database. Molecular docking simulation with most frequent MHC class-II(MHC II) and class-I(MHC I) molecules showed that these epitopes could bind within HLA binding grooves to elicit an immune response. Conclusions: Data in our present study revealed the notion that the epitopes from G and M proteins might be the target for peptide-based subunit vaccine design against He V and Ni V. However, the biochemical analysis is necessary to experimentally validate the interaction of epitopes individually with the MHC molecules through elucidation of immunity induction. | Chayan Kumar Saha Mahbub Hasan Saddam Hossain Asraful Jahan Abul Kalam Azad | 2017 | Asian Pacific Journal of Tropical Medicine2017，10，6： | 0 |
| 18 | History,epidemiology,vaccine and transmission of coronavirus disease 2019 (COVID-19):a quick review显示文摘Coronavirus belonging to family Coronaviridae is a large group of viruses causing respiratory and gastrointestinal diseases.The outbreak of 2019-novel coronavirus has created panic in the whole world after being transmitted from Wuhan,China in December 2019.A large number of people are affected throughout the world that forced a solitary situation in the affected areas confining common people to their homes to prevent its spread.Cellular receptors in humans for 2019-novel coronavirus are found to be same as for severe acute respiratory syndrome coronavirus,the first human pandemic of 21st century,however,2019-novel coronavirus is highly contagious,virulent and mutable than the severe acute respiratory syndrome coronavirus.The most attractive site for vaccine development against 2019-novel coronavirus is the spike glycoprotein which is crucial for receptor binding,membrane fusion via conformational changes,virus internalization,and host tissue tropism or spike inactivation through antibody induced destabilization.First outbreak was in December 2019,later on at the end of 2020,the mortality ratio decreased that created a sigh of temporary relief in the globe.Summer season was considered as one of the sources combating infection and preventing spread of virus.However,for the last few months,suddenly a huge outrage of new variants of coronavirus disease 2019 are capturing attention of the entire population of earth endangering lives of people irrespective of their ages and communities.Researchers must focus on the inventions and discoveries of either preventive or therapeutic medicines that precisely target the spike proteins that enable the severe acute respiratory syndrome coronavirus-2’s entry into a host cell.In this article,we have highlighted various vaccines being approved for emergency use by Federal Investigating Agency to combat the disastrous effects of pandemic on humanity.Mutated variants have created an alarming situation for the health care workers,researchers and scientists to consider the possible mutants and their threat to humanity in the coming years.Further,we have tried to create awareness for developing a global internet community to promote a barrier-free connectivity among all corners of the world to facilitate humanity in case of a category 5 coronavirus disease-hurricane,a term used by researchers for future threats of pandemic. | Rabia Altaf Asra Iftikhar Rabia Haq Bushra Zahoor Muhammad Zaini Asmawi Mohamed Khadeer Ahamed Basheer | 2021 | Life Research2021，4，3： | 0 |
| 19 | Malnutrition associated factors on children under 5 years old in Lhaviyani Atoll,Maldives显示文摘In this report,we aimed to analyze the prevalence of undernutrition and associated factors among children under 5 years of age in Lhaviyani Atoll,Maldives.A total of 800 children(under 5 years old) and their mothers were selected for this study.Data was collected by using a pretested questionnaire and anthropometric measurements were taken from the hospital record book.Chi-square tests and multivariate logistic regression were used to find the association between nutritional status and determinants.The distribution of height for age and weight for age in surveyed children in Maldives was skewed to the left compared with the WHO standard.The prevalence of undernutrition based on underweight(10.75%),stunting(13.5%),and wasting(9.60%) was estimated to be 23.85% among children.Child age,gender and mother’s education were significantly associated with undernutrition(P<0.05).Our survey highlighted that better nutritional interventions are needed to improve child health in this region. | Mariyam Asra Xiaofang Lin Ijaz Ul Haq Asfia Banu Pasha Yingying Shao Rui Qin Manli Hu Ye Ding Zhixu Wang | 2020 | The Journal of Biomedical Research2020，34，4： | 0 |
| 20 | 我男友是色狼 | Asra Q.Nomani | 2009 | 跨世纪(时文博览)2009，0，10X： | 0 |
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