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| 1 | Efficacy and side effects of praziquantel in the treatment of Schistosomiasis mansoni in schoolchildren in Shesha Kekele Elementary School,Wondo Genet,Southern Ethiopia显示文摘Objective:To evaluate the efficacy and side effects of praziquantel(PZQ) in the treatment of schistosomiasis in Ethiopia.Methods:In a cross-sectional study,stool specimens were collected from randomly selected 299 school children in Shesha Kekele Elementary School,Wondo Genet, Southern Ethiopia,in April 2010.Stool specimens were examined using a single Kato-Katz thick smear for Schistosoma mansoni(5.mansoni) ova.Children who were found positive for S.mansoni were treated with a single oral dose of PZQ at 40 mg/kg bw and interviewed for treatment-related symptoms 24 hours after drug administration.Four weeks post-treatment,stool specimens were collected from the same children and examined following the same procedure as in the pretreatment.Drug efficacy was determined based on cure and egg reduction rates.Results:Pretreatment prevalence of S.mansoni infection was 74.9%with geometric mean egg count of 268. The evaluated generic PZQ produced an overall cure rate of 73.6%(P<0.000 1,OR:8.33,CI:5.3-13.1) and egg reduction rate of 68.2%(P=0.03,F=0.64).The cure rate showed significant association with age(x^2=H,P=0.004),the highest rate being observed in the 15-22 age group.83%of S. mansoni infected children showed various treatment-related symptoms,the most frerjiient being headache,nausea,and abdominal pain.These symptoms were associated with age(P<0.001) and pre-treatment intensity of infection(P<0.05).Conclusions:The present observations revealed relatively lower cure and egg reduction rates of the PZQ evaluated as compared to previous reports for other PZQ brands in Ethiopia.Hence,in depth studies are recommended to clarify whether the present relatively lower cure rate is the actual cure rate of the praziquantel evaluated,treatment failure,or reduced susceptibility of the parasite.Treatment-related side effects observed were transient and tolerable. | Berhanu Erko Abraham Degarege Konjit Tadesse Asnake Mathiwos Mengistu Legesse | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，3： | 3 |
| 2 | Timeline visualization of research fronts显示文摘 | Morris A Yen G Wu Z Asnake B | 2003 | Journal of the American Society for Information Science and Technology2003，54，5： | 1 |
| 3 | Timeline visualization of research fronts 显示文摘 | Morris A Yen G Wu Z Asnake B | 2003 | Journal of the American Society for Inforrnatien Science and Technology2003，54，5： | 1 |
| 4 | An automated method for mapping physical soil and water conservation structures on cultivated land using GIS and remote sensing techniques显示文摘An efficient and reliable automated model that can map physical Soil and Water Conservation(SWC) structures on cultivated land was developed using very high spatial resolution imagery obtained from Google Earth and Arc GIS?ERDAS IMAGINE?and SDC Morphology Toolbox for MATLAB and statistical techniques. The model was developed using the following procedures:(1) a high-pass spatial filter algorithm was applied to detect linear features,(2) morphological processing was used to remove unwanted linear features,(3) the raster format was vectorized,(4) the vectorized linear features were split per hectare(ha) and each line was then classified according to its compass directionand(5) the sum of all vector lengths per class of direction per ha was calculated. Finallythe direction class with the greatest length was selected from each ha to predict the physical SWC structures. The model was calibrated and validated on the Ethiopian Highlands. The model correctly mapped 80% of the existing structures. The developed model was then tested at different sites with different topography. The results show that the developed model is feasible for automated mapping of physical SWC structures. Thereforethe model is useful for predicting and mapping physical SWC structures areas across diverse areas. | Asnake MEKURIAW Andreas HEINIMANN Gete ZELEKE Hans HURNI Kaspar HURNI | 2017 | Journal of Geographical Sciences2017，27，1： | 1 |
| 5 | Achievements and prospects of genomics-assisted breeding in three legume crops of the semi-arid tropics显示文摘 | Rajeev K. Varshney S. Murali Mohan Pooran M. Gaur N.V.P.R. Gangarao Manish K. Pandey Abhishek Bohra Shrikant L. Sawargaonkar Annapurna Chitikineni Paul K. Kimurto Pasupuleti Janila K.B. Saxena Asnake Fikre Mamta Sharma Abhishek Rathore Aditya Pratap Shail | 2012 | Biotechnology Advances2012，，： | 1 |
| 6 | Improving Group Member Participation of 4th Year Section A Civil Engineering extension Students in integrated Project Work at Debre Markos University显示文摘Group work is a form of voluntary association of members benefiting from cooperative learning,which enhances the total output of the activity.Therefore,group discussion is a way for active participants to explore new ideas.Based on the previously observed practices in 4th year civil engineering students at Debre Markos University,the group member participations was not pleasing.The objective of this study was to identify the core causes of low participation of group members in their project work and to take actions for improving group member participation.The data collection method used questionnaires and interviews and was analyzed using Microsoft Excels.Action research done in civil engineering 4th year Extension courses focused on continuous advising and instruction.These practices have achieved a good understanding of how to increase active participation in their group work activities.Therefore,a main conclusion of this project is that an active learning method helps the students to share skill,knowledge and attitude to each other. | Mulusew Minuyelet Zewdie Zeleke Damtie Almaw Mamaru Gashaw Kebede Fnotework Asnake | 2021 | Journal of International Education and Practice2021，4，1： | 0 |
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