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| 1 | Hepatocellular carcinoma: Epidemiology, risk factors and pathogenesis显示文摘Hepatocellular carcinoma (HCC) is the commonest primary malignant cancer of the liver in the world. Given that the burden of chronic liver disease is expected to rise owing to increasing rates of alcoholism, hepatitis B and C prevalence and obesity-related fatty liver disease, it is expected that the incidence of HCC will also increase in the foreseeable future. This article summarizes the international epidemiology, the risk factors and the pathogenesis of HCC, including the roles of viral hepatitis, toxins, such as alcohol and aflatoxin, and insulin resistance. | Asmaa Ibrahim Gomaa Shahid A Khan Mireille B Toledano Imam Waked Simon D Taylor- Robinson | 2008 | World Journal of Gastroenterology2008，14，27： | 78 |
| 2 | Diagnosis of hepatocellular carcinoma显示文摘Hepatocellular carcinoma (HCC) is one of the commonest cancers worldwide, particularly in parts of the developing world, and is increasing in incidence. This article reviews the current modalities employed for the diagnosis of HCC, including serum markers, radiological techniques and histological evaluation, and summarises international guidelines for the diagnostic approach to HCC. | Asmaa I Gomaa Shahid A Khan Edward LS Leen Imam Waked Simon D Taylor-Robinson | 2009 | World Journal of Gastroenterology2009，15，11： | 44 |
| 3 | Recent advances in multidisciplinary management of hepatocellular carcinoma显示文摘The incidence of hepatocellular carcinoma(HCC) is increasing, and it is currently the second leading cause of cancer-related death worldwide. Potentially curative treatment options for HCC include resection, transplantation, and percutaneous ablation, whereas palliative treatments include trans-arterial chemoembolization(TACE), radioembolization, and systemic treatments. Due to the diversity of available treatment options and patients' presentations, a multidisciplinaryteam should decide clinical management of HCC, according to tumor characteristics and stage of liver disease. Potentially curative treatments are suitable for very-early- and early-stage HCC. However, the vast majority of HCC patients are diagnosed in later stages, where the tumor characteristics or progress of liver disease prevent curative interventions. For patients with intermediate-stage HCC, TACE and radioembolization improve survival and are being evaluated in addition to potentially curative therapies or with systemic targeted therapy. There is currently no effective systemic chemotherapy, immunologic, or hormonal therapy for HCC, and sorafenib is the only approved moleculartargeted treatment for advanced HCC. Other targeted agents are under investigation; trials comparing new agents in combination with sorafenib are ongoing. Combinations of systemic targeted therapies with local treatments are being evaluated for further improvements in HCC patient outcomes. This article provides an updated and comprehensive overview of the current standards and trends in the treatment of HCC. | Asmaa I Gomaa Imam Waked | 2015 | World Journal of Hepatology2015，7，4： | 15 |
| 4 | Platelet-albumin-bilirubin score - a predictor of outcome of acute variceal bleeding in patients with cirrhosis显示文摘BACKGROUND The albumin-bilirubin(ALBI)score was validated as a prognostic indicator in patients with liver disease and hepatocellular carcinoma.Incorporating platelet count in the platelet-albumin-bilirubin(PALBI)score improved validity in predicting outcome of patients undergoing resection and ablation.AIM To evaluate the PALBI score in predicting outcome of acute variceal bleeding in patients with cirrhosis.METHODS The data of 1517 patients with cirrhosis presenting with variceal bleeding were analyzed.Child Turcotte Pugh(CTP)class,Model of End-stage Liver Disease(MELD),ALBI and PALBI scores were calculated on admission,and were correlated to the outcome of variceal bleeding.Areas under the receivingoperator characteristic curve(AUROC)were calculated for survival and rebleeding.RESULTS Mean age was 52.6 years;1176 were male(77.5%),69 CTP-A(4.5%),434 CTP-B(29.2%),1014 CTP-C(66.8%);306 PALBI-1(20.2%),285 PALBI-2(18.8%),and 926 PALBI-3(61.1%).Three hundred and thirty-two patients died during hospitalization(21.9%).Bleeding-related mortality occurred in 11%of CTP-B,28%of CTP-C,in 21.8%of PALBI-2 and 34.4%of PALBI-3 patients.The AUROC for predicting survival of acute variceal bleeding was 0.668,0.689,0.803 and 0.871 for CTP,MELD,ALBI and PALBI scores,respectively.For predicting rebleeding the AUROC was 0.681,0.74,0.766 and 0.794 for CTP,MELD,ALBI and PALBI scores,respectively.CONCLUSION PALBI score on admission is a good prognostic indicator for patients with acute variceal bleeding and predicts early mortality and rebleeding. | Omar Elshaarawy Naglaa Allam Eman Abdelsameea Asmaa Gomaa Imam Waked | 2020 | World Journal of Hepatology2020，12，3： | 13 |
| 5 | Ciprofloxacin adsorption from aqueous solution onto chemically prepared carbon from date palm leaflets显示文摘A chemically prepared carbon was synthesized from date palm leaflets via sulphuric acid carbonization at 160℃.Adsorption of ciprofloxacin(CIP) from aqueous solution was investigated in terms of time,pH,concentration,temperature and adsorbent status(wet and dry).The equilibrium time was found to be 48 hr.The adsorption rate was enhanced by raising the temperature for both adsorbents,with adsorption data fitting a pseudo second-order model well.The activation energy,E a,was found to be 17 kJ/mol,indicating a diffusion-controlled,physical adsorption process.The maximum adsorption was found at initial pH 6.The wet adsorbent showed faster removal with higher uptake than the dry adsorbent,with increased performance as temperature increased(25-45℃).The equilibrium data were found to fit the Langmuir model better than the Freundlich model.The thermodynamic parameters showed that the adsorption process is spontaneous and endothermic.The adsorption mechanism is mainly related to cation exchange and hydrogen bonding. | El-Said Ibrahim El-Shafey Haider Al-Lawati Asmaa Soliman Al-Sumri | 2012 | Journal of Environmental Sciences2012，24，9： | 9 |
| 6 | Validation of modified albumin-bilirubin-TNM score as a prognostic model to evaluate patients with hepatocellular carcinoma显示文摘BACKGROUND An ideal staging system for hepatocellular carcinoma(HCC)should rely on the hepatic reserve function and tumor burden.With the improvement in diagnostic and treatment strategies for HCC,in addition to recent treatment of viral hepatitis,finding a suitable assessment tool for hepatic reserve has become mandatory.AIM To validate a recently proposed modified albumin-bilirubin-TNM(mALBI-T)grade as a prognostic model for patients with HCC in Egypt.METHODS For patients diagnosed with HCC,Child-Turcotte-Pugh(CTP)score,Barcelona Clinic Liver Cancer(BCLC)stage,albumin-bilirubin(ALBI),plateltetalbumin– bilirubin(PALBI),ALBI-based BCLC,ALBI-T and mALBI-T grades were estimated.Patients were followed from time of diagnosis to date of death or date of data collection if they remained alive.Overall survival and received treatments were determined.Survival data were analyzed.RESULTS A total of 1910 patients were included(mean age,57 years;1575 males).At presentation,50.6%had CTP A,36.1%had CTP B and 13.4%had CTP C;12%had ALBI grade 1,62.3%had ALBI grade 2 and 24.7%had ALBI grade 3.Overall median survival was 13 mo;survival was better in patients with ALBI 1 than in those with ALBI 2 and 3(28.6 vs 14 and 5.8 mo,respectively,P<0.001).Patients with ALBI-T grades 0 and 1 had better survival than those with ALBI-T grades 2,3,4 and 5(P<0.001).The modified ALBI-T showed better stratification and significant improvement in prediction of survival.CONCLUSION ALBI-T grade is a superior prognostic tool that selects patients with HCC who have better liver reservoir and tumor stage.mALBI-T is a better prognostic model in patients with HCC. | Omar Elshaarawy Alzhraa Alkhatib Mostafa Elhelbawy Asmaa Gomaa Naglaa Allam Ayman Alsebaey Eman Rewisha Imam Waked | 2019 | World Journal of Hepatology2019，11，6： | 7 |
| 7 | 氧气条件对矿化垃圾修复石油污染土壤的影响显示文摘通过对比不同氧气条件下矿化垃圾修复石油污染土壤的效果、降解产物、生态毒性、酶活性和微生物群落,分析了氧气条件对矿化垃圾修复石油污染土壤的影响.结果表明,添加矿化垃圾在厌氧、好氧和厌氧⁃好氧3种氧气条件下对微生物修复石油污染土壤都有较好的强化效果.修复的最佳氧气条件为好氧,好氧修复后土壤总石油烃(TPH)去除率最高,土壤生态毒性最小.厌氧⁃好氧试验的TPH去除率和土壤生态毒性介于厌氧和好氧试验之间.好氧条件更利于小分子石油类污染物的降解,修复后链烷烃、烯烃、芳香烃和芳香烃衍生物的去除率最高,新增污染物主要为环烷烃、含卤有机物和含氮杂环有机物.而厌氧条件更利于大分子石油类污染物的降解,修复后环烷烃、环烷烃衍生物和含氮杂环有机物的去除率最高,新增污染物主要为支链烷烃、环烷烃和含氧环状有机物.好氧条件下土壤微生物总活性更高,而厌氧条件下土壤微生物多样性更高.纲水平上,厌氧和好氧条件下土壤优势细菌都为放线菌纲、β⁃变形菌纲和γ⁃变形菌纲,优势真菌都为粪壳菌纲.但在属水平上优势菌差异很大,好氧条件下的石油烃降解菌更多,而厌氧条件下的石油烃衍生物降解菌更多. | 刘庆梅 Asmaa Hussein Ali 刘丹 | 2021 | 环境科学学报2021，41，2： | 6 |
| 8 | 纯钛超声微弧氧化-化学镀铜涂层的制备及抗菌性显示文摘为了赋予纯钛口腔种植体表面涂层生物活性及抗菌性,发挥酸蚀、微弧氧化技术、碱处理及化学镀铜技术各自优势,在TA2纯钛表面制备载铜生物涂层。研究了镀铜时间和温度对载铜含量及涂层表面形貌、结合力和抗菌性的影响。结果表明:钛基体酸蚀获得表面腐蚀均匀的微纳米结构,为超声微弧氧化提供了更多的氧化物生长空间;钛超声微弧氧化涂层碱处理使陶瓷层Ti O2活化,并利于载铜;利用多孔涂层进行化学镀铜时,涂层中铜元素含量随化学镀铜温度的升高和时间增长而增大,而涂层结合力随着化学镀铜时间增长而下降;50℃下化学镀铜3 min时,涂层抗菌率为98.3%,表面铜含量适宜,载铜破坏生物膜的形成使细菌黏附的微环境发生改变,造成细菌难以正常生长,实现了抗菌效果。 | 李慕勤 Asmaa Alzalab 新朋礼 蔡丁森 田钦文 马臣 Maudhah Alaa Ali | 2016 | 材料保护2016，49，12： | 6 |
| 9 | Liver stiffness as a predictor of hepatocellular carcinoma behavior in patients with hepatitis C related liver cirrhosis显示文摘Background: Risk strati cation and prognostication of hepatocellular carcinoma (HCC) help to improve patient outcome. Herein we investigated the role of liver stiffness measurement (LSM) in the prediction of HCC behavior. Methods: Totally 121 na ve patients with HCC were included. HCC radiological evaluation and staging were done. LSM was measured using virtual touch quanti cation. Patients were divided into early to intermediate HCC (BCLC-0, A and B) and late HCC (BCLCC and D). HCC was treated according to the BCLC stage. HCC recurrence-free interval was estimated. Results: The mean LSM inside the tumor was signi cantly lower than the peri-tumoral area and the cirrhotic non-cancerous liver parts (P<0.001). In late HCCs stage, the mean LSM inside the tumor and in the peri-tumoral tissue was lower than the corresponding values in the early to intermediate HCCs stage (P<0.001). LSM inside the tumor and in the peri-tumoral tissue negatively correlated with serum AFP, tumor vascular invasion, and stage (P<0.05). The recurrence-free interval was directly correlated to LSM inside the tumor and inversely to LSM in cirrhotic non tumorous liver part. Kaplan-Meier analysis showed that the recurrence-free interval was signi cantly longer in patients with LSM inside the tumor of ≥1.25m/s compared to those with LSM inside the tumor of<1.25m/s. Conclusions: LSM can serve as a potential non-invasive predictor for HCC clinical behavior and the recurrence-free interval following loco-regional treatments. | Sameh A Lashen Mohamed M Elshafei Fahmy H Hablass Eman A Alsayed Asmaa A Hassan | 2020 | Hepatobiliary & Pancreatic Diseases International2020，19，1： | 4 |
| 10 | Ascites and alpha-fetoprotein improve prognostic performance of Barcelona Clinic Liver Cancer staging显示文摘AIM: To assess how ascites and alpha-fetoprotein(AFP) added to the Barcelona Clinic Liver Cancer(BCLC) staging predict hepatocellular carcinoma survival.METHODS: The presence of underlying cirrhosis, ascites and encephalopathy, Child-Turcotte-Pugh(CTP) score, the number of nodules, and the maximum diameter of the largest nodule were determined at diagnosis for 1060 patients with hepatocellular carcinoma at a tertiary referral center for liver disease in Egypt. Demographic information, etiology of liver disease, and biochemical data(including serum bilirubin, albumin, international normalized ratio, alanine and aspartate aminotransferases, and AFP) were evaluated. Staging of the tumor was determined at the time of diagnosis using the BCLC staging system; 496 patients were stage A and 564 patients were stage B. Patients with mild ascites on initial ultrasound, computed tomography, or clinical examination, and who had a CTP score ≤ 9 were included in this analysis. All patients received therapy according to the recommended treatment based on the BCLC stage, and were monitored from the time of diagnosis to the date of death or date of data collection. The effect of the presence of ascites and AFP level on survival was analyzed.RESULTS:At the time the data were censored,123/496(24.8%)and 218/564(38.6%)patients with BCLC stages A and B,respectively,had died.Overall mean survival of the BCLC A and B patients during a three-year follow-up period was 31 mo[95%confidence interval(95%CI):29.7-32.3]and 22.7mo(95%CI:20.7-24.8),respectively.The presenceof ascites,multiple focal lesions,large tumor size,AFP level and CTP score were independent predictors of survival for the included patients on multivariate analysis(P<0.001).Among stage A patients,18%had ascites,33%had AFP≥200 ng/m L,and 8%had both.Their median survival in the presence of ascites was shorter if AFP was≥200 ng/m L(19 mo vs 24 mo),and in the absence of ascites,patients with AFP≥200 ng/m L had a shorter survival(28mo vs 39 mo).For stage B patients,survival for the corresponding groups was 12,18,19 and 22 mo.The one-,two-,and three-year survival rates for stage A patients without ascites and AFP<200 ng/m L were94%,77%,and 71%,respectively,and for patients with ascites and AFP≥200 ng/m L were 83%,24%,and 22%,respectively(P<0.001).Adding ascites and AFP≥200 ng/m L improved the discriminatory ability for predicting prognosis(area under the curve,0.618vs 0.579 for BCLC,P<0.001).CONCLUSION:Adding AFP and ascites to the BCLC staging classification can improve prognosis prediction for early and intermediate stages of hepatocellular carcinoma. | Asmaa I Gomaa Alzhraa Al-Khatib Wael Abdel-Razek Mohammed Saad Hashim Imam Waked | 2015 | World Journal of Gastroenterology2015，21，18： | 3 |
| 11 | Association of vascular endothelial growth factor-634G/C and receptor for advanced glycation end products G82S gene polymorphisms with diabetic retinopathy显示文摘AIM: To investigate the association of receptor for advanced glycation end products(RAGE) G82S and vascular endothelial growth factor(VEGF)-634 G/C gene polymorphisms with diabetic retinopathy(DR).METHODS: Our cross-sectional study included 61 diabetic patients, 12 of them had proliferative diabetic retinopathy(PDR), 15 had non proliferative diabetic retinopathy(NPDR), 34 had no diabetic retinopathy(NDR)and 61 healthy controls. Participants were tested for RAGE G82S and VEGF-634 G/C polymorphisms by polymerase chain reaction-restriction fragment length polymorphism.RESULTS: We found a significant association between VEGF-634 G/C polymorphism and PDR as PDR patients had increased incidence of VEGF-634 CC genotype compared to NDR patients [odds ratio for CC vs(GC +GG)=6.5, 95% CI=1.5-27.8, P =0.021]. Also VEGF-634 CC genotype and C allele were significantly higher in the PDR than in NPDR patients, which is a novel finding in our study(P =0.024, 0.009 respectively). The mean triglycerides level was significantly higher in diabetic patients with CC genotype(P =0.01) as compared to patients with other genotypes. All cases and control subjects were of the same heterozygous RAGE 82G/S genotype.CONCLUSION: Patients carrying VEGF-634 C polymorphism have a higher risk of PDR development,so VEGF-634 G/C polymorphism could be used as a predictive marker for PDR in diabetic patients. We could not find a significant association between RAGE G82S polymorphism and DR. | Asmaa Kamal Khaled Abu Eleinen Ibrahem Siam | 2016 | International Journal of Ophthalmology(English edition)2016，9，8： | 2 |
| 12 | Molecular mechanisms of the anti-obesity potential effect of Moringa oleifera in the experimental model显示文摘Objective: To elucidate the molecular mechanisms of the potent anti-obesity effect of Moringa oleifera Lam.(M. oleifera) ethanolic extract and to clarify the link between these mechanisms and the associated metabolic and vascular risks in the experimental model of visceral obesity.Methods: M. oleifera ethanolic extract was orally administered at 600 mg/kg body weight in obese female rats daily for 12 weeks. At the end of treatment, body weight was determined, and the atherogenic index, coronary artery index, glucose level, insulin resistance status, liver and kidney functions were assessed. Also, the m RNA of leptin, adiponectin and resistin in visceral adipose tissue was determined by quantitative real time-PCR.Results: The results showed that M. oleifera extract down-regulated m RNA expression of leptin and resistin, while it up-regulated adiponectin gene expression in obese rats relative to untreated obese control counterparts. This amelioration of genes expression was paralleled by a reduction in body weight and improvement of the atherogenic index and coronary artery index, as well as glucose level and insulin resistance value without adverse effects on liver or kidney functions, versus the untreated obese control ones.Conclusions: It is reasonable to assume that the anti-obesity, anti-atherogenic and antidiabetic properties of M. oleifera are mechanistically achieved via working directly on the adipokines of the visceral adipose tissue. Therefore, M. oleifera may be a good therapeutic candidate for the symptoms of metabolic syndrome. | Fateheya Mohamed Metwally Hend Mohamed Rashad Hanaa Hamdy Ahmed Asmaa Ahmed Mahmoud Ehab Ragaa Abdol Raouf Aboelfetoh Mohamed Abdalla | 2017 | Asian Pacific Journal of Tropical Biomedicine2017，7，3： | 2 |
| 13 | Egyptian heavy vacuum gas oil hydrotreating over Co-Mo/CNT and Co-Mo/γ-Al2O3 catalysts显示文摘The catalytic activity of CoMoS /CNT towards the Egyptian heavy vacuum gas oil hydrotreating was studied. The delivered CNT was functionalized with 6 mol /L HNO_3. The CNT were loaded with 12% MoO_3( by weight) and 0.7 Co /Mo atomic ratio with impregnation methods. The γ-Al_2O_3 catalyst was also prepared by impregnation method to compare both catalysts activities.The analysis tools such XRD,Raman spectroscopy,TEM,and BET were used to characterize the catalysts. The autoclave reactor was used to operate the hydrotreating experiments. The hydrotreating reactions were tested at various operating conditions of temperature 325-375 ℃,pressure 2-6 MPa,time 2-6 h,and catalyst /oil ratio( by weight) of 1 ∶75,1 ∶33 and 1 ∶10. The results revealed that the CoMoS /CNT was highly efficient for the hydrotreating more than the CoMoS /γ-Al_2O_3. Also, the hydrodesulfurization( HDS) increased with increasing catalyst /oil ratio. Additionally,results showed that the optimum condition was temperature 350℃,pressure 4 MPa,catalyst /oil ratio of 1 ∶75 for 2 h. Furthermore,even at low CoMoS /CNT catalyst /oil ratio of 1 ∶75,an acceptable HDS of 77.1% was achieved. | W.Ahmed Hoda,S.Ahmed H.S.El-Sheshtawy Nadia,A.Mohamed Asmaa,I.Zahran | 2016 | 燃料化学学报2016，44，7： | 2 |
| 14 | 电子医疗数据云服务安全显示文摘医疗信息技术的重要性最近几年得到了戏剧性的提升。研究者、开发者以及公司已经开始努力发展手机、网络、桌面以及企业E健康应用。这些发展又提升了E健康应用和健康信息系统(HIS)之间的互通和数据交换的重要性,进而导致了对敏感数据和数据交换的安全性的担忧。这篇文章强调了基于云计算服务的HISs和E健康应用之间的标准化数据交换机制和互通性。这项服务在包含有大量的病人记录的HISs上提供一个单一的检索电子医疗记录和搜索此类信息的E健康应用的入口。再者,这项研究提出一个统一的安全平台提供给开发者、安全医疗提供者和组织者一个连接框架的渠道去检索和管理医疗记录,以及提供给大量注册者个人一个连接通道到自己的医疗记录(PHR)。此项服务和平台已经在埃及亚历山大大学医学院示范的医生、病人和医院管理者之间进行了定性的评估。评估结果比较乐观,不过原型的实现还需要更多的研究。 | Asmaa S.Radwan Ayman A.Abdel-Hamid Yasser Hanafy 尹捍东 | 2013 | 电子世界2013，，17： | 2 |
| 15 | CFD investigation of the agitation in the desupersaturation during the wet-process phosphoric acid(WPPA)process显示文摘Desupersaturation is a complex cooling operation that involves hydrodynamic,thermal and mechanical phenomena.This process requires continuous agitation to avoid fouling problems and sludge deposition.The current work aims to investigate the well mixedness in the desupersaturation tank for optimal performance.For this purpose,a multi-fluid CFD study was conducted based on the Euler–Euler modeling approach,considering a multiphase flow involving a liquid phase(phosphoric acid)and a poly-dispersed solid phase,i.e.a sludge with three different sizes where each size is considered as a separate phase.First,the hydrodynamic behavior of the flow within the agitated desupersaturator is analyzed through the investigation of the velocity fields as well as the power and pumping numbers,to determine both the agitator capacity to pump the flow and its power consumption during the operation.Then,in order to assess the mixture homogeneity,we evaluated the solid suspension in the desupersaturation reactor following conventional methods and two new proposed methodologies:the first approach is to evaluate the suspension quality in the mixing system by compartment and the second consists on the assessment of the uniform convergence of the solid concentration.Furthermore,we calculated the time required to achieve a full suspension at different solid concentrations.On other hand,we conducted a detailed analysis of the solid distribution dependency on the impeller rotational speed at different solid volume fraction,which allows a good understanding of the parameters controlling the homogenization in the desupersaturator. | Asmaa Hadane Lhachmi Khamar Saad Benjelloun Abderrahman Nounah Mohammed Khamar | 2020 | Chinese Journal of Chemical Engineering2020，28，8： | 2 |
| 16 | Perinatal outcome of monochorionic in comparison to dichorionic twin pregnancies 显示文摘 | Nihal AR Asmaa AR Murtadha AK | 2013 | Oman Medical Journal2013，28，3： | 1 |
| 17 | Assessment of river contamination by estrogenic compounds in Paris area (France) 显示文摘 | Cargouet M Perdiz D Asmaa M S | 2004 | Science of the Total Environment2004，324，： | 1 |
| 18 | Endothelial dysfunction in geriatric diabetic patients: the role of microalbuminuria in elderly type 2 diabetic patients? A randomized controlled study显示文摘 | Mohamed A. Helaly Hussein A. Sheashaa El Sayed Z. Hatata Ansaf B. Youssef Asmaa Hegazi Ibrahim A. Abdel-Aal | 2007 | International Urology and Nephrology2007，，1： | 1 |
| 19 | Mathematical modeling of female breast cancer in Japan显示文摘Cancer incidence rates are significantly diferent all over the world.Breast cancer is affected by many factors,the most important being genetics and lifestyle.The aim of this paper is to study the mutation mechanisms of breast cancer for Japanese women by fitting the incidence data of three high-quality population areas in Japan from 1985 to 2010.To achieve this goal,we have set up multi-stage models within the mathematical model of Moolgavkar,Venzon,and Knudson.Such models take both mutation rates and clonal expansion rates as parameters in each compartment into consideration.Based on our simulation outcomes,two to twelve driver mutations are sufficient in the pathway to female breast cancer in Japan.On the other hand,a previous study demonstrated that breast cancer in American women requires two to fourteen gene mutations to get a cancerous cell.Moreover,the 3-stage mat hematical model is the optimal model as it fits clinical data very nicely for all affected cases of females in Japan and the US.The genetic instability has a promincnt effect on the tumorigenesis of Japanese females caused by the first four driver mutations.The calculated results for Japanese women are compared with previous works for American women. | Ahmed Nagah Asmaa Amer Xinan Zhang | 2020 | International Journal of Biomathematics2020，13，4： | 1 |
| 20 | Serum IGFBP?3 is a more effective predictor than IGF?1 and IGF-2 forthe development of hepatocellular carcinoma in patients with chronic HCV infection显示文摘 | Eiman Aleem Ayman Elshayeb Nihal Elhabachi Amal Mansour Ahmed Gowily Asmaa Hela | 2012 | Oncology Letters2012，，3： | 1 |
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