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| 1 | 联合应用沙利度胺和脂质体阿霉素治疗复发性卵巢上皮性癌和腹膜癌的初步研究显示文摘目的:评价联合应用沙利度胺与脂质体阿霉素治疗复发性卵巢上皮性癌和腹膜癌的疗效和毒副作用。方法:将9例经手术和术后泰素+卡铂化疗后复发患者纳入本研究。每4周予以脂质体阿霉素30~50mg/m^2化疗,共3~8个疗程;同时每日予以沙利度胺100~300mg,其剂量从100mg/d开始,此后每2周增加50~100mg。通过体检、影像学检查和测定CA125水平评价治疗效果。结果:9例患者的中位年龄为56岁(35~81岁),FIGO分期为ⅢB~Ⅳ期。本次化疗的中位疗程数是6个疗程。中位随访时间为18.5个月。最常见的不良反应为疲劳(55.6%)和神经系统症状(55.6%)。3例患者出现Ⅲ度副反应,1例为无力、1例过敏性皮疹和1例末梢神经感觉异常。根据RECIST标准评价有病灶的6例患者疗效,2例部分缓解,2例治疗中疾病无进展,1例病情进展,1例失访。另有2例CA125升高的患者,在联合化疗3~4个疗程后CA125水平降低50%以上。1例二次肿瘤细胞减灭术后化疗的患者治疗后随访36个月无肿瘤复发迹象。在随访的8例患者中,中位疾病无进展时间为6.5个月(0~36个月);中位总的生存时间为20.5个月(8~36个月)。结论:联合应用沙利度胺与脂质体阿霉素治疗复发性卵巢上皮性癌具有可接受的毒副作用,同时具有一定的治疗效果。 | 郭红燕 Nelson N. Teng John K. Chan Amreen Husain Deirdre Stieglitz Jonathon S Bereck | 2008 | 现代妇产科进展2008，17，2： | 5 |
| 2 | Herbal option for diabetes: an overview显示文摘 | Amreen Fatima Parul Agrawal Prem Prakash Singh | 2012 | Asian Pacific Journal of Tropical Disease2012，，： | 2 |
| 3 | Chemical speciation of respirable suspended particulate matter during a major firework festival in India显示文摘 | Sayantan Sarkar Pandit S. Khillare Darpa S. Jyethi Amreen Hasan Musarrat Parween | 2010 | Journal of Hazardous Materials2010，，1： | 1 |
| 4 | Oncogenic potential of Human Papillomavirus (HPV) and its relation with cervical cancer显示文摘 | Rabia F Amreen Z Khalida K | 2011 | Virology Journal2011，8，： | 1 |
| 5 | Vein graft failure显示文摘 | Christopher D. Owens Warren J. Gasper Amreen S. Rahman Michael S. Conte | 2015 | Journal of Vascular Surgery2015，，1： | 1 |
| 6 | OCEANS: A Randomized, Double-Blind, Placebo-Controlled Phase III Trial of Chemotherapy With or Without Bevacizumab in Patients With Platinum-Sensitive Recurrent Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer显示文摘 | Carol Aghajanian Stephanie V. Blank Barbara A. Goff Patricia L. Judson Michael G. Teneriello Amreen Husain Mika A. Sovak Jing Yi Lawrence R. Nycum | 2012 | Journal of Clinical Oncology2012，，17： | 1 |
| 7 | Endoscopic management and outcomes of pregnant women hospitalized for nonvariceal upper GI bleeding: a nationwide analysis显示文摘 | Geoffrey C. Nguyen Amreen M. Dinani Kevin Pivovarov | 2010 | Gastrointestinal Endoscopy2010，，5： | 1 |
| 8 | BRCA1 Up-Regulation Is Associated with Repair-mediated Resistance to cis-Diamminedichloroplatinum (Ⅱ)显示文摘 | Amreen Husain Guoshun He Ennapadam S | 1998 | Cancer Res1998，58，： | 1 |
| 9 | Detection and identifi cation of bact erial enteropathogens by polymerase chain reaction and conventional techniques in childhood acute gastroenteritis in Gaza, Palestine 显示文摘 | Abu El amreen FH Abed AA Sharif FA | 2007 | Int J Infect Dis2007，11，： | 1 |
| 10 | OCEANS: A Randomized, Double-Blind, Placebo-Controlled Phase III Trial of Chemotherapy With or Without Bevacizumab in Patients With Platinum-Sensitive Recurrent Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer显示文摘 | Carol Aghajanian Stephanie V. Blank Barbara A. Goff Patricia L. Judson Michael G. Teneriello Amreen Husain Mika A. Sovak Jing Yi Lawrence R. Nycum | 2012 | Journal of Clinical Oncology2012，，17： | 1 |
| 11 | Oncogenic potential of human papillornavirus(HPV) and its relation with cervical cancer显示文摘 | Rabia F Amreen Z Khalida K | 2011 | Virol J2011，8，3： | 1 |
| 12 | Epigenetic control of autophagy in women’s tumors:role of non-coding RNAs显示文摘Cancer remains the second leading cause of death worldwide and a major public health and economic issue.To reduce the burden,new approaches are necessary to diagnose the disease at early stages and improve clinical outcomes of cancer patients,for which understanding the molecular mechanisms of carcinogenesis is crucial.Autophagy is a pro-survival pathway that ensures the removal and renewal of cellular macromolecular structures,thus playing a crucial role in the maintenance of cellular homeostasis.Dysregulation of autophagy can favor chemoresistance and survival of dormant cancer cells,thus favoring cancer progression and relapse.Several studies report dysregulated expression of long non-coding RNAs and micro-RNAs acting as tumor suppressors or tumor promoters by targeting genes involved in the autophagy pathway.Here,we focus on the role played by non-coding RNAs-mediated regulation of autophagy in development and progression of cancers in women.Understanding how epigenetics can impact autophagy might open novel therapeutic strategies in the fight against cancers in women. | Chiara Vidoni Letizia Vallino Alessandra Ferraresi Eleonora Secomandi Amreen Salwa Menaka Chinthakindi Alessandra Galetto Danny N Dhanasekaran Ciro Isidoro | 2021 | Journal of Cancer Metastasis and Treatment2021，7，1： | 0 |
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