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| 1 | Updated Worldwide Survey on the Methods, Efficacy, and Safety of Catheter Ablation for Human Atrial Fibrillation显示文摘 | Riccardo Cappato Hugh Calkins Shih-Ann Chen Wyn Davies Yoshito Iesaka Jonathan Kalman You-Ho Kim George Klein Andrea Natale Douglas Packer Allan Skanes Federico Ambrogi Elia Biganzoli | 2010 | Circulation: Arrhythmia and Electrophysiology2010，，1： | 2 |
| 2 | Differential expression of genes involved in the epigenetic regulation of cell identity in normal human mammary cell commitment and differentiation显示文摘The establishment and maintenance of mammary epithelial cell identity depends on the activity of a group of proteins, collectively called maintenance proteins, that act as epigenetic regulators of gene transcription through DNA methylation, histone modification, and chromatin remodeling. Increasing evidence indicates that dysregulation of these crucial proteins may disrupt epithelial cell integrity and trigger breast tumor initiation. Therefore, we explored in silico the expression pattern of a panel of 369 genes known to be involved in the establishment and maintenance of epithelial cell identity and mammary gland remodeling in cell subpopulations isolated from normal human mammary tissue and selectively enriched in their content of bipotent progenitors, committed luminal progenitors, and differentiated myoepithelial or differentiated luminal cells. The results indicated that, compared to bipotent cells, differentiated myoepithelial and luminal subpopulations were both characterized by the differential expression of 4 genes involved in cell identity maintenance: CBX6 and PCGF2, encoding proteins belonging to the Polycomb group, and SMARCD3 and SMARCE1, encoding proteins belonging to the Trithorax group. In addition to these common genes, the myoepithelial phenotype was associated with the differential expression of HDAC1, which encodes histone deacetylase 1, whereas the luminal phenotype was associated with the differential expression of SMARCA4 and HAT1, which encode a Trithorax protein and histone acetylase 1, respectively. The luminal compartment was further characterized by the overexpression of ALDH1A3 and GATA3, and the down-regulation of NOTCH4 and CCNB1, with the latter suggesting a block in cell cycle progression at the G2 phase. In contrast, myoepithelial differentiation was associated with the overexpression of MYC and the down-regulation of CCNE1, with the latter suggesting a block in cell cycle progression at the G1 phase. | Danila Coradini Patrizia Boracchi Saro Oriana Elia Biganzoli Federico Ambrogi | 2014 | Chinese Journal of Cancer2014，33，10： | 2 |
| 3 | Response to radiofrequency ablation of pulmonary tumours: a prospective, intention-to-treat, multicentre clinical trial (the RAPTURE study)显示文摘 | Riccardo Lencioni Laura Crocetti Roberto Cioni Robert Suh Derek Glenn Daniele Regge Thomas Helmberger Alice R Gillams Andrea Frilling Marcello Ambrogi Carlo Bartolozzi Alfredo Mussi | 2008 | Lancet Oncology2008，，7： | 2 |
| 4 | Systematic review of ablative therapy for the treatment of renal allograft neoplasms显示文摘BACKGROUND To date,there are no guidelines on the treatment of solid neoplasms in the transplanted kidney.Historically,allograft nephrectomy has been considered the only reasonable option.More recently,nephron-sparing surgery (NSS) and ablative therapy (AT) have been proposed as alternative procedures in selected cases.AIM To review outcomes of AT for the treatment of renal allograft tumours.METHODS We conducted a systematic review according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2009 Checklist.PubMed was searched in March 2019 without time restrictions for all papers reporting on radiofrequency ablation (RFA),cryoablation (CA),microwave ablation (MWA),high-intensity focused ultrasound (HIFU),and irreversible electroporation (IRE) of solid tumours of the kidney allograft.Only original manuscripts describing actual cases and edited in English were considered.All relevant articles were accessed in full text.Additional searches included all pertinent references.Selected studies were also assessed for methodological quality using a tool based on a modification of the Newcastle Ottawa scale.Data on recipient characteristics,transplant characteristics,disease characteristics,treatment protocols,and treatment outcomes were extracted and analysed.Given the nature and the quality of the studies available (mostly retrospective case reports and small retrospective uncontrolled case series),a descriptive summary was provided.RESULTS Twenty-eight relevant studies were selected describing a total of 100 AT procedures in 92 patients.Recipient age at diagnosis ranged from 21 to 71 years whereas time from transplant to diagnosis ranged from 0.1 to 312 mo.Most of the neoplasms were asymptomatic and diagnosed incidentally during imaging carried out for screening purposes or for other clinical reasons.Preferred diagnostic modality was Doppler-ultrasound scan followed by computed tomography scan,and magnetic resonance imaging.Main tumour types were: papillary renal cell carcinoma (RCC) and clear cell RCC.Maximal tumour diameter ranged from 5 to 55 mm.The vast majority of neoplasms were T1a N0 M0 with only 2 lesions staged T1b N0 M0.Neoplasms were managed by RFA (n = 78),CA (n = 15),MWA (n = 3),HIFU (n = 3),and IRE (n = 1).Overall,3 episodes of primary treatment failure were reported.A single case of recurrence was identified.Follow-up ranged from 1 to 81 mo.No cancer-related deaths were observed.Complication rate was extremely low (mostly < 10%).Graft function remained stable in the majority of recipients.Due to the limited sample size,no clear benefit of a single procedure over the other ones could be demonstrated.CONCLUSION AT for renal allograft neoplasms represents a promising alternative to radical nephrectomy and NSS in carefully selected patients.Properly designed clinical trials are needed to validate this therapeutic approach. | Evaldo Favi Nicholas Raison Federico Ambrogi Serena Delbue Maria Chiara Clementi Luca Lamperti Marta Perego Matteo Bischeri Mariano Ferraresso | 2019 | World Journal of Clinical Cases2019，7，17： | 2 |
| 5 | Sociological and Philosophical Studies: twenty years of controversy显示文摘 | Ambrogi Alvarez | 1996 | Phil & Tech 1:3-4 Spring1996，，： | 1 |
| 6 | Intercalation Compounds of Hydrotalcite-like Anionic Clays With Anti-inflammatory Agents,Ⅱ:Uptake of Diclofenac for a Controlled Release Formulation显示文摘 | Ambrogi V Fardella G Grandolini G | | 0，，03： | 1 |
| 7 | Long-term results ofradiofrequency ablation treatment of stage 1 non-small cell lungcancer: a prospective intention-to-treat study 显示文摘 | Ambrogi MC Fanucchi 0 Cioni R | 2011 | J Thorac Oncol2011，6，12： | 1 |
| 8 | Prognostic impact of VEGF,CD31,CD34,and CD105 expression and tumour vessel invasion after radical surgery for IB-IIA non-small cell lung cancer显示文摘 | Mineo TC Ambrogi V Baldi A | | 0，，06： | 1 |
| 9 | 查看详情显示文摘 | Ambrogi V Fardella G Grandolini G Perioli L | | 0，，： | 1 |
| 10 | Prolonged survival after extracranial metastasectomy from synchronous resectable lung canccr显示文摘 | Ambrogi V Tonini G Mineo TC | 2001 | Ann Surg Oncol2001，8，8： | 1 |
| 11 | Prognostic impact of VEGF, CD3L , CD34, and CD105 expression and tumour vessel invasion alter radical surgery for IB - IIA non - small cell lung cancer显示文摘 | Minco T C Ambrogi V Baldi A | 2004 | J Clin Pathol2004，957，： | 1 |
| 12 | Risk factors for postpartum hemorrhage in a cohort of 6011 Italian women显示文摘 | Biguzzi E Franchi F Ambrogi F | | 0，，04： | 1 |
| 13 | Changing indications for thorac6tomy in blunt chest trauma after the advent of videothoracoscopy显示文摘 | Mineo TC Ambrogi V Cristino B | 1999 | J Trauma1999，47，6： | 1 |
| 14 | Prognostic impact of VEGF, CD31, CD34, and CD105 expression and tumour vessel invasion after radical surgery for ⅠB- ⅡA non-small cell lung cancer 显示文摘 | Mineo TC Ambrogi V Baldi A | 2004 | J Clin Pathol2004，57，6： | 1 |
| 15 | Prognostic impact of VEGF,CD31,CD34,and CD105 expression and tumour vessel invasion after radical surgery for IB-ⅡA non-small cell lung cancer显示文摘 | Mineo TC Ambrogi V Baldi A Rabitti C Bol ero P Vincenzi B | 2004 | J Clin Pathol2004，57，6： | 1 |
| 16 | Percutmleous radio - fequency ablation of lung tumours : results in the mid - term 显示文摘 | AMBROGI M C LUCCHI M DINI P | 2006 | Eur J Cardiothorac Surg2006，30，1： | 1 |
| 17 | Prognostic impact VEGF, CD31,CD34,and CD105 expression and tumor vessel invasion after radical surgery for IB-IIA non-small cell lung cancer显示文摘 | Mineo TC Ambrogi V Baldi A | 2004 | J Clin Pathol2004，57，6： | 1 |
| 18 | Prognostic impact VEGF,CD31,CD34 and CD105 expression and tumor vessel invasion after radical surgery for Ⅰ B,Ⅱ A non-small cell lung cance显示文摘 | Mineo TC Ambrogi V Baldi A | 2004 | J Clin Pathol2004，57，6： | 1 |
| 19 | p53 status identifies two subgroups of triple-negative breast cancers with distinct biological features 显示文摘 | Biganzoli E Coradini D Ambrogi F | 2011 | Jpn J Clin Oncol2011，41，2： | 1 |
| 20 | Transxiphoid hand-assisted videothoracoscopic surgery 显示文摘 | Mineo T C Ambrogi V Mineo D | 2007 | Ann Thorac Surg2007，83，5： | 1 |
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