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| 1 | Ketamine use disorder:preclinical,clinical,and neuroimaging evidence to support proposed mechanisms of actions显示文摘Ketamine,a noncompetitive N-methyl-D-aspartate(NMDA)receptor antagonist,has been exclusively used as an anesthetic in medicine and has led to new insights into the pathophysiology of neuropsychiatric disorders.Clinical studies have shown that low subanesthetic doses of ketamine produce antidepressant effects for individuals with depression.However,its use as a treatment for psychiatric disorders has been limited due to its reinforcing effects and high potential for diversion and misuse.Preclinical studies have focused on understanding the molecular mechanisms underlying ketamine’s antidepressant effects,but a precise mechanism had yet to be elucidated.Here we review different hypotheses for ketamine’s mechanism of action including the direct inhibition and disinhibition of NMDA receptors,aminomethylphosphonic acid receptors(AMPAR)activation,and heightened activation of monoaminergic systems.The proposed mechanisms are not mutually exclusive,and their combined influence may exert the observed structural and functional neural impairments.Long term use of ketamine induces brain structural,functional impairments,and neurodevelopmental effects in both rodents and humans.Its misuse has increased rapidly in the past 20 years and is one of the most common addictive drugs used in Asia.The proposed mechanisms of action and supporting neuroimaging data allow for the development of tools to identify‘biotypes’of ketamine use disorder(KUD)using machine learning approaches,which could inform intervention and treatment. | Leah Vines Diana Sotelo Allison Johnson Evan Dennis Peter Manza Nora D.Volkow Gene-Jack Wang | 2022 | Intelligent Medicine2022，2，2： | 2 |
| 2 | Stability of hybrid simulation of dynamic systems显示文摘 | Allison J S Johnson H M | 1979 | Mathematics and Computers in Simulation1979，21，3： | 1 |
| 3 | Achieving National cholesterol Education program goals for low density Liprorotein cholesterol in cardiac patients:imprortance of diet,exercise,weight control,and drug therapy 显示文摘 | Squires RW Johnson BD | 1999 | Mago Clin Proc1999，74，46： | 1 |
| 4 | Heart rate recovery and prognosis in heart failure patients显示文摘 | Vera Kubrychtova Thomas P. Olson Kent R. Bailey Prabin Thapa Thomas G. Allison Bruce D. Johnson | 2009 | European Journal of Applied Physiology2009，，1： | 1 |
| 5 | Cracking in concrete tension flanges of composite T-beams 显示文摘 | Johnson R P Allison R W | 1983 | The Structural Engineer1983，61，3： | 1 |
| 6 | Behavioral Interventions to Prevent Childhood Obesity: A Systematic Review and Metaanalyses of Randomized Trials显示文摘 | Celia C. Kamath Kristin S. Vickers Angela Ehrlich Lauren McGovern Jonathan Johnson Vibha Singhal Remberto Paulo Allison Hettinger Patricia J. Erwin Victor M. Montori | 2008 | The Journal of Clinical Endocrinology & Metabolism2008，，： | 1 |
| 7 | Emergence of Fluoroquinolone Resistance in Outpatient Urinary Escherichia coli Isolates显示文摘 | Luke Johnson Allison Sabel William J. Burman Rachel M. Everhart Marcie Rome Thomas D. MacKenzie Jeanne Rozwadowski Philip S. Mehler Connie Savor Price | 2008 | The American Journal of Medicine2008，，10： | 1 |
| 8 | Oophorectomy, hormone therapy, and subclinical coronary artery disease in women with hysterectomy: the Women’s Health Initiative coronary artery calcium study显示文摘 | Matthew A. Allison JoAnn E. Manson Robert D. Langer J. Jeffrey Carr Jacques E. Rossouw Mary B. Pettinger Lawrence Phillips Barbara B. Cochrane Charles B. Eaton Philip Greenland Susan Hendrix Judith Hsia Julie R. Hunt Rebecca D. Jackson Karen C. Johnson Le | 2008 | Menopause2008，，4： | 1 |
| 9 | Correspondence between the adult treatment panel Ⅲ criteria for metabolic syndrome and insulin resistance显示文摘 | Sierra-Johnson J Johnson B D Allison T G | 2006 | Diabetes Care2006，29，3： | 1 |
| 10 | Rapid thrombelastography (r-TEG) identifies hypercoagulability and predicts thromboembolic events in surgical patients显示文摘 | Jeffry L. Kashuk Ernest E. Moore Allison Sabel Carlton Barnett James Haenel Tuan Le Michael Pezold Jerry Lawrence Walter L. Biffl C. Clay Cothren Jeffrey L. Johnson | 2009 | Surgery2009，，4： | 1 |
| 11 | Achieving national cholesterol education program goals for lowdensity lipoprotein cholesterol in cardiac patients: importance of diet, exercise, weight control, and drug therapy 显示文摘 | ALLISON T G SQUIRES R W JOHNSON B D | 2000 | Journal of Cardiopulmonary Rehabilitation2000，20，3： | 1 |
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