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| 1 | Axitinib plus gemcitabine versus placebo plus gemcitabine in patients with advanced pancreatic adenocarcinoma: a double-blind randomised phase 3 study显示文摘 | Hedy L Kindler Tatsuya Ioka Dirk J Richel Jaafar Bennouna Richard Létourneau Takuji Okusaka Akihiro Funakoshi Junji Furuse Young Suk Park Shinichi Ohkawa Gregory M Springett Harpreet S Wasan Peter C Trask Paul Bycott Alejandro D Ricart Sinil Kim Eric Van | 2011 | Lancet Oncology2011，，3： | 4 |
| 2 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 3 | Gastric cancer in young people under 30 years of age: worse prognosis, or delay in diagnosis?显示文摘 | Horacio N López-Basave Diaz Romero C Alejandro Padilla Rosciano Melchor Ruan J Silvio A. ?amendys-Silva Vela Sarmiento I Ruiz Molina JM Calderillo Ruiz G Flavia Morales-Vásquez Abelardo Meneses Garcia Angel Herrera-Gomez | 2013 | Cancer Management and Research (default)2013，，： | 2 |
| 4 | Information Fusion for Wireless Sensor Networks: Methods, Models, and Classifications 显示文摘 | Eduardo F N Antonio A F L Alejandro C F | 2007 | ACM Computing Surveys2007，39，3： | 1 |
| 5 | Genetic Polymorphisms in MTHFR (C677T, A1298C), MTR (A2756G) and MTRR (A66G) Genes Associated With Pathological Characteristics of Prostate Cancer in the Ecuadorian Population显示文摘 | Andrés López-Cortés Gabriela Jaramillo-Koupermann María J. Mu?oz Alejandro Cabrera Carolina Echeverría Felipe Rosales Nicolás Vivar César Paz-y-Mi?o | 2013 | The American Journal of the Medical Sciences2013，，： | 1 |
| 6 | Adaptive control for a radio-controlled helicopter in a vertical flying stand 显示文摘 | Alejandro D Rogelio L Pedro C | 2004 | International Journal of Adaptive Control and Signal Processing2004，18，5： | 1 |
| 7 | Phenolic composition of skins from four Carmenet grape varieties ( Vitis vinifera L.) during ripening显示文摘 | Elías Obreque-Slier álvaro Pe?a-Neira Remigio López-Solís Alejandro Cáceres-Mella Héctor Toledo-Araya Américo López-Rivera | 2013 | LWT - Food Science and Technology2013，，： | 1 |
| 8 | Rainfall partitioning within semiarid juniper communities: effects of event size and canopy cover显示文摘 | OWENS M K LYONS R K ALEJANDRO C L | 2006 | Hydrological Processes2006，20，： | 1 |
| 9 | Patterning Organic Single-Crystal Transistor Arrays 显示文摘 | Briseno Alejandro L Mannsfeld Stefan C B Ling Mang M | 2006 | Nature2006，444，7121： | 1 |
| 10 | Rainfall partitioning within semiarid juniper communities : Effects of event size and canopy cov- er显示文摘 | Owens M K Lyons R K Alejandro C L | 2006 | Hydrological Processes2006，20，15： | 1 |
| 11 | Artificial neural networks study of the catalytic reduction of resazurin: Stopped-flow injection kinetic-spectrophotometric determination of Cu(II) and Ni(II) 显示文摘 | Diana M Magni Alejandro C Olivieri Adrian L Bonivardi | 2005 | Analytica Chimica Acta2005，528，2： | 1 |
| 12 | Effect of aerobic Gram-positive heterotrophic bacteria associated with Artemia franciscana cysts on the survival and development of its larvae 显示文摘 | Orozco-Medina César Maeda-Martínez Alejandro M López-Cortés Alejandro | 2002 | Aqua2002，213，： | 1 |
| 13 | Sex determination in flowering plants显示文摘 | STEPHEN L D ALEJANDRO C U | 1993 | The Plant Cell1993，5，： | 1 |
| 14 | Adaptation of left ventricular morphology to long-term training in sprint-and endurance- trained elite runners显示文摘 | Alejandro L A Mariano G C Isaas L B | 2006 | Biomedical and life sciences and medicine2006，96，6： | 1 |
| 15 | Solving nonstationary classification problems with coupled support vector machines显示文摘 | Guillermo L G Lucas C U Alejandro C H | 2011 | IEEE Trans on Knowledge on Neural Network2011，22，1： | 1 |
| 16 | Chlorine dioxidedose, water quality and temperature affect the oxidative status oftomato processing water and its ability to inactivate Salmonella显示文摘 | Gabriela L V Alejandro T C Adrian S et at | 2012 | Food Control2012，26，1： | 1 |
| 17 | Rainfall partitioning within semiarid juniper communities:Effects of event size and canopy cover 显示文摘 | Owens M K Lyons R K Alejandro C L | 2006 | Hydrological Processes2006，20，： | 1 |
| 18 | Artificial neural networks study of the catalytic reduction of resazurin: stopped flow injection kinetic-spectrophotometric determination of Cu(II)and Ni(II) 显示文摘 | Diana M Magni Alejandro C Olivieri Adrian L Bonivardl | 2005 | Analytiea Chimica Acta2005，528，： | 1 |
| 19 | Presence of Echinococcus oligarthrus (Diesing, 1863) Luhe, 1910 in Lynx rufus texensis Alien, 1895 from San Fernando, Tamaulipas State, in north-east Mexico显示文摘 | NARCISO S L FERNANDO J G ALEJANDRO C R | 1996 | Int J Parasltol1996，26，7： | 1 |
| 20 | Inhibition effects observed between dibenzothiophene and carbazole during the hydrotreating process 显示文摘 | LAREDO G C ALEJANDRO M ANTONIO D L R J | 2004 | Applied Catalysis A: General2004，265，1： | 1 |
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