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| 1 | Fulminant myocarditis in adults: a narrative review显示文摘Fulminant myocarditis(FM)is an uncommon syndrome characterized by sudden and severe hemodynamic compromise secondary to acute myocardial inflammation,often presenting as profound cardiogenic shock,life-threatening ventricular arrhythmias and/or electrical storm.FM may be refractory to conventional therapies and require mechanical circulatory support(MCS).The immune system has been recognized as playing a pivotal role in the pathophysiology of myocarditis,leading to an increased focus on immunosuppressive treatment strategies.Recent data have highlighted not only the fact that FM has significantly worse outcomes than non-FM,but that prognosis and management strategies of FM are heavily dependent on histological subtype,placing greater emphasis on the role of endomyocardial biopsy in diagnosis.The impact of subtype on severity and prognosis will likewise influence how aggressively the myocarditis is managed,including whether MCS is warranted.Many patients with refractory cardiogenic shock secondary to FM end up requiring MCS,with venoarterial extracorporeal membrane oxygenation demonstrating favorable survival rates,particularly when initiated prior to the development of multiorgan failure.Among the challenges facing the field are the need to more precisely identify immunopathophysiological pathways in order to develop targeted therapies,and the need to better optimize the timing and management of MCS to minimize complications and maximize outcomes. | Santiago Montero Darryl Abrams Enrico Ammirati Florent Huang Dirk WDonker Guillaume Hekimian Cosme García-García Antoni Bayes-Genis Alain Combes Matthieu Schmidt | 2022 | Journal of Geriatric Cardiology2022，19，2： | 3 |
| 2 | Usefulness of procalcitonin for the diagnosis of ventilator-associated pneumonia显示文摘 | Charles-Edouard Luyt Alain Combes Catherine Reynaud Guillaume Hekimian Ania Nieszkowska Marc Tonnellier Alexandra Aubry Jean-Louis Trouillet Maguy Bernard Jean Chastre | 2008 | Intensive Care Medicine2008，，8： | 3 |
| 3 | Continuous venovenous haemodiafiltration versus intermittent haemodialysis for acute renal failure in patients with multiple-organ dysfunction syndrome: a multicentre randomised trial显示文摘 | Christophe Vinsonneau Christophe Camus Alain Combes Marie Alyette Costa de Beauregard Kada Klouche Thierry Boulain Jean-Louis Pallot Jean-Daniel Chiche Pierre Taupin Paul Landais Jean-Fran?ois Dhainaut | 2006 | The Lancet2006，，9533： | 1 |
| 4 | Lipase- catalysed transesterification of high oleic sunflower oil 显示文摘 | Valerie Dossat Didier Combes Alain Marry | 2002 | Enzyme and Microbial Technology2002，30，： | 1 |
| 5 | Efficient lipase catalysed production of a lubricant and surfactant using a continuous solvent - free process显示文摘 | Valerie Dossat Didier Combes Alain Marry | 2002 | journal of biotechnology2002，，97： | 1 |
| 6 | Efficient lipase catalysed production of a lubricant and surfactant using a continuous solvent-free process显示文摘 | Valerie Dossat Didier Combes Alain Marty | 2002 | Journal of Biotechnology2002，97，： | 1 |
| 7 | Estimation of left ventricular systolic function by single transpulmonary thermodilution显示文摘 | Alain Combes Jean-Baptiste Berneau Charles-Edouard Luyt Jean-Louis Trouillet | 2004 | Intensive Care Medicine2004，，7： | 1 |
| 8 | Virus-induced acute respiratory distress syndrome: Epidemiology, management and outcome显示文摘 | Charles-édouard Luyt Alain Combes Jean-Louis Trouillet Ania Nieszkowska Jean Chastre | 2011 | La Presse Medicale2011，，12： | 1 |
| 9 | Diffusion Tensor Imaging to Predict Long-term Outcome after Cardiac Arrest: A Bicentric Pilot Study显示文摘 | Charles-Edouard Luyt Damien Galanaud Vincent Perlbarg Audrey Vanhaudenhuyse Robert D. Stevens Rajiv Gupta Hortense Besancenot Alexandre Krainik Gérard Audibert Alain Combes Jean Chastre Habib Benali Steven Laureys Louis Puybasset | 2012 | Anesthesiology2012，，6： | 1 |
| 10 | Usefulness of procalcitonin for the diagnosis of ventilator-associated pneumonia显示文摘 | Charles-Edouard Luyt Alain Combes Catherine Reynaud Guillaume Hekimian Ania Nieszkowska Marc Tonnellier Alexandra Aubry Jean-Louis Trouillet Maguy Bernard Jean Chastre | 2008 | Intensive Care Medicine2008，，8： | 1 |
| 11 | Continuous venovenous haemodiafiltration versus intermittent haemodialysis for acute renal failure in patients with multiple-organ dysfunction syndrome: a multicentre randomised trial显示文摘 | Christophe Vinsonneau Christophe Camus Alain Combes Marie Alyette Costa de Beauregard Kada Klouche Thierry Boulain Jean-Louis Pallot Jean-Daniel Chiche Pierre Taupin Paul Landais Jean-Fran?ois Dhainaut | 2006 | The Lancet2006，，9533： | 1 |
| 12 | Lipased catalysed transesterification of high oleic sunflower oil 显示文摘 | Valerie Dossat Didier Combes Alain Marty | 2002 | Enzyme and Microbial Technology2002，30，： | 1 |
| 13 | Continuous venovenous haemodiafi ltration versus intermittent haemodialysis for acute renal failure in patients with multiple-organ dysfunction syndrome:a multicentre randomised trial显示文摘 | Christophe Vinsonneau Christophe Camus Alain Combes | | 0，，： | 1 |
| 14 | Lipase-catalysed transesterification of high oleic sunflower oil显示文摘 | Valerie Dossat Didier Combes Alain Marty | 2002 | Enzyme and Microbial Technology2002，30，： | 1 |
| 15 | Extracorporeal membrane oxygenation in COVID-19 associated acute respiratory distress syndrome:A narrative review显示文摘Venovenous extracorporeal membrane oxygenation(VV-ECMO)is an established rescue therapy in the management of refractory acute respiratory distress syndrome(ARDS).Although ECMO played an important role in previous respiratory viral epidemics,concerns about the benefits and usefulness of this technique were raised during the coronavirus disease 2019(COVID-19)pandemic.Indeed,the mortality rate initially reported in small case series from China was concerning and exceeded 90%.A few months later,the critical care community published the findings from several observational cohorts on the use of extracorporeal membrane oxygenation(ECMO)in COVID-19-related ARDS.Contrary to the preliminary results,data from the first surge supported the use of ECMO in experienced centers because the mortality rate was comparable to those from the ECMO to Rescue Lung Injury in Severe ARDS(EOLIA)trial or other large prospective studies.However,the mortality rate of the population with severe disease evolved during the pandemic,in conjunction with changes in the management of the disease and the occurrence of new variants.The results from subsequent studies confirmed that the outcomes mainly depend on strict patient selection and center expertise.In comparison with non-COVID-related ARDS,the duration of ECMO for COVID-related ARDS was longer and increased over time.Clinicians and decision-makers must integrate this finding in the ECMO decision-making process to plan their ICU capacity and resource allocation.This narrative review summarizes the current evidence and specific considerations for ECMO use in COVID-19-associated ARDS. | Benjamin Assouline Alain Combes Matthieu Schmidt | 2023 | Journal of Intensive Medicine2023，3，1： | 0 |
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