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| 1 | Heme in intestinal epithelial cell turnover, differentiation, detoxification, inflammation, carcinogenesis, absorption and motility显示文摘胃肠道被经历包含两极分裂,区别和细胞死亡的经常的更新的一张单层上皮衬里。另外,上皮的衬里分开由保护上皮免受被突破的伤害的防御机制从内部周围的无菌的环境发生在肠的腔的消化和吸收的敌对过程。对这些防御过程中央是合成他我和它的分解代谢由他我氧合酶(惊讶) 。饮食他我也是为被收起的身体的铁的重要来源由 enterocyte 未经触动。这评论在肠道在 heme/HO 的多样的性质上描述最近的文学。在房间 cycle/apoptosis, xenobiotics 的 detoxification,氧化压力,发炎,结肠癌的发展, heme 铁吸收和肠的活动性的规定的 heme/HO 的角色明确地被检验。 | Phillip S Oates Adrian R West | 2006 | World Journal of Gastroenterology2006，12，27： | 8 |
| 2 | Mechanisms of heme iron absorption:Current questions and controversies显示文摘Iron is a critical micronutrient, and iron derived from heme contributes a large proportion of the total iron absorbed in a typical Western diet. Heme iron is absorbed by different mechanisms than non-heme iron, but despite considerable study over many years these mechanisms remain poorly understood. This review provides an overview of the importance of heme iron in the diet and discusses the two prevailing hypotheses of heme absorption; namely receptor mediated endocytosis of heme, and direct transport into the intestinal enterocyte by recently discovered heme transporters. A specific emphasis is placed on the questions surrounding the site of heme catabolism and the identity of the enzyme that performs this task. Additionally, we present the hypothesis that a non-heme iron transport protein may be required for heme iron absorption and discuss the experiences of our laboratory in examining this hypothesis. | Adrian R West Phillip S Oates | 2008 | World Journal of Gastroenterology2008，14，26： | 5 |
| 3 | Accountability and accessibility:ensuring the evidence of e-governance in Australia显示文摘 | Adrian Cunningham Margaret Phillips | 2005 | Aslib Proceedings2005，，4： | 1 |
| 4 | Discharges in mam-malian sympathetic nerves 显示文摘 | Adrian ED Bronk DW Phillips G | 1932 | J Physiol1932，74，2： | 1 |
| 5 | 加快大型数据中心服务的可重构结构显示文摘数据中心的工作负载要求高计算能力、灵活性、能效和低成本。同时改善所有这些因素非常具有挑战性。为了推进数据中心超出商用服务器设计可以提供的能力,我们设计并构建了一个可组合、可重构的结构,来加速部分大型软件服务。结构的每个实例都由嵌入48台机器的半机架6×8二维环面高端Stratix V FPGA组成。每台服务器中都放置了一个FPGA,可以通过PCIe来访问,并用成对的10 Gb SAS电缆直接连接到其他FPGA。在本文中,我们描述了这种结构在1,632台服务器组(bed)的中等规模的部署,并测量了其在加快Bing搜索引擎方面的功效。我们描述了系统的要求和架构,详细介绍了关键技术挑战,以及使系统在出现故障情况下保持鲁棒性所需的解决方案,还有根据排名候选文档测量的系统性能、功率和弹性。在高负载时,一定范围内的可重构结构提高了每台服务器固定延迟分布的吞吐量排名95%——或在保持等效吞吐量时,减少29%的尾延迟。 | Andrew Putnam Adrian M.Caulfield Eric S.Chung Derek Chiou Kypros Constantinide John Demme Hadi Esmaeilzadeh Jeremy Fowers Gopi Prashanth Gopal Jan Gray Michael Haselman Scott Hauck Stephen Heil Amir Hormati Joo-Young Kim Sitaram Lanka James Larus Eric Peterson Simon Pope Aaron Smith Jason Thong Phillip Yi Xiao Doug Burger | 2015 | 中国集成电路2015，24，1： | 1 |
| 6 | Physical Characteristics of Plasma Antenna显示文摘 | John Phillip Rayner Adrian Philip Whichllo and Andrew Desmond Cheetham | 2004 | IEEE Transactions on plasma science2004，32，1： | 1 |
| 7 | Antioxidants versus corticosteroids in the treatment of severe alcoholic hepatitis—A randomised clinical trial显示文摘 | Martin Phillips Howard Curtis Bernard Portmann Nora Donaldson Adrian Bomford John O’Grady | 2005 | Journal of Hepatology2005，，4： | 1 |
| 8 | Hepatic Expression of Hepatocyte Growth Factor Gene mRNA in Acute Liver Failure显示文摘 | Phillip Harrison Christopher Gove Adrian Bomford | 2000 | Digestive Diseases and Sciences2000，45，10： | 1 |
| 9 | Photochemical synthesis of N-arylbenzophenanthridine selective estrogen receptor modulators (SERMs)显示文摘 | Grese T A Adrian M D Phillips D L | 2001 | J Med Chem2001，44，17： | 1 |
| 10 | Antisense inhibition of brainrenin-angiotensin system decreased blood pressure in chronic 2-kidney,1 clip hypertensiverats显示文摘 | Shuntaro Kagiyama Adrian VM Ian Phillips | 2001 | Hypertens2001，37，2： | 1 |
| 11 | Photochemical synthesis of N-arylben zophenanthridine selective estrogen receptor modulators(SERMs) 显示文摘 | Grese TA Adrian MD Phillips DL | 2001 | J Med Chem2001，44，17： | 1 |
| 12 | 进击人生的21次冒险显示文摘还在为下一站的冒险找寻灵感吗?这里就有你想要的答案。你可以划船穿越加拿大西部的荒野,或者乘列车贯穿整个西伯利亚;可以畅游亚马孙河,甚至在苏丹大金字塔的脚下沉入梦乡。多位热爱冒险的旅行作家已经将那些令人兴奋的旅行目的地全盘托出。而你唯一的任务就是,从中选出自己最钟爱的一个,抓紧时间出发吧。 | Julia Buckley Amelia Duggan Emma Gregg Jamie Lafferty Ben Lerwill Aaron Millar Adrian Phillips Emma Thomson 李雯蕊(译) | 2022 | 时尚旅游2022，，8： | 0 |
| 13 | Principles for managing marine ecosystems prone to tipping points显示文摘As climatic changes and human uses intensify,resource managers and other decision makers are taking actions to either avoid or respond to ecosystem tipping points,or dramatic shifts in structure and function that are often costly and hard to reverse.Evidence indicates that explicitly addressing tipping points leads to improved management outcomes.Drawing on theory and examples from marine systems,we distill a set of seven principles to guide effective management in ecosystems with tipping points,derived from the best available science.These principles are based on observations that tipping points(1)are possible everywhere,(2)are associated with intense and/or multifaceted human use,(3)may be preceded by changes in earlywarning indicators,(4)may redistribute benefits among stakeholders,(5)affect the relative costs of action and inaction,(6)suggest biologically informed management targets,and(7)often require an adaptive response to monitoring.We suggest that early action to preserve system resilience is likely more practical,affordable,and effective than late action to halt or reverse a tipping point.We articulate a conceptual approach to management focused on linking management targets to thresholds,tracking early-warning signals of ecosystem instability,and stepping up investment in monitoring and mitigation as the likelihood of dramatic ecosystem change increases.This approach can simplify and economize management by allowing decision makers to capitalize on the increasing value of precise information about threshold relationships when a system is closer to tipping or by ensuring that restoration effort is sufficient to tip a system into the desired regime. | Kimberly A.Selkoe Thorsten Blenckner Margaret R.Caldwell Larry B.Crowder Ashley L.Erickson Timothy E.Essington James A.Estes Rod M.Fujita Benjamin S.Halpern Mary E.Hunsicker Carrie V.Kappel Ryan P.Kelly John N.Kittinger Phillip S.Levin John M.Lynham Megan E.Mach Rebecca G.Martone Lindley A.Mease Anne KSalomon Jameal F.Samhouri Courtney Scarborough Adrian C.Stier Crow White Joy Zedler | 2015 | Ecosystem Health and Sustainability2015，1，5： | 0 |
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