|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Viral hepatitis prevalence in patients with active and latent tuberculosis显示文摘AIM: To assess the prevalence of hepatitis B virus(HBV) and hepatitis C virus(HCV) infection and association with drug induced liver injury(DILI) in patients undergoing anti-tuberculosis(TB) therapy.METHODS: Four hundred and twenty nine patients with newly diagnosed TB- either active disease or latent infection- who were due to commence antiTB therapy between September 2008 and May 2011 were included. These patients were prospectively tested for serological markers of HBV, HCV and human immunodeficiency virus(HIV) infections- hepatitis B core antigen(HBc Ag), hepatitis B surface antigen(HBs Ag), hepatitis B e antigen, Ig G and Ig M antibody to HBc Ag(anti-HBc), HCV Ig G antibody and HIV antibody using a combination of enzyme-linked immunosorbent assay, Western blot assay and polymerase chain reaction techniques. Patients were reviewed at least monthly during the TB treatment initiation phase. Liver function tests were measured prior to commencement of antiTB therapy and 2-4 wk later. Liver function tests were also performed at any time the patient had significant nausea, vomiting, rash, or felt non-specifically unwell. Fisher's exact test was used to measure significance in comparisons of proportions between groups. A P value of less than 0.05 was considered statistically significant.RESULTS: Of the 429 patients, 270(62.9%) had active TB disease and 159(37.1%) had latent TB infection. 61(14.2%) patients had isolated anti-HBc positivity, 11(2.6%) were also HBs Ag positive and 7(1.6%) were HCV-antibody positive. 16/270 patients with active TB disease compared to 2/159 patients with latent TB infection had markers of chronic viral hepatitis(HBs Ag or HCV antibody positive; P = 0.023). Similarly the proportion of HBs Ag positive patients were significantly greater in the active vs latent TB infection group(10/43 vs 1/29, P = 0.04). The prevalence of chronic HBV or HCV was significantly higher than the estimated United Kingdom prevalence of 0.3% for each. We found no association between DILI and presence of serological markers of HBV or HCV. Three(5.3%) patients with serological markers of HBV or HCV infection had DILI compared to 25(9.5%) patients without; P = 0.04.CONCLUSION: Viral hepatitis screening should be considered in TB patients. DILI risk was not increased in patients with HBV/HCV. | Hesam Ahmadi Nooredinvand David W Connell Mahmoud Asgheddi Mohammed Abdullah Marie O'Donoghue Louise Campbell Melissa I Wickremasinghe Ajit Lalvani Onn Min Kon Shahid A Khan | 2015 | World Journal of Gastroenterology2015，21，29： | 7 |
| 2 | Probiotics in poultry:Modes of action Worlds Poult显示文摘 | Jin L Z Ho Y W Abdullah N | 1997 | Sci J1997，53，： | 1 |
| 3 | Tectonostratigraphic controls on turbidite depositional processes in Brunei显示文摘 | Allman W P Tromp J P Abdullah I | 2000 | AAPG Bulletin2000，84，9： | 1 |
| 4 | Application of flexible printed circuit board (FPCB) in personal computer motherboards: Focusing on mechanical performance 显示文摘 | LEONG W ABDULLAH M KHOR C | 2012 | Microelectronics Reliability2012，52，4： | 1 |
| 5 | The dieta- ry protein requirement of the Malaysian mahseer, Tor tambroides (Bleeker), and the lack of protein-sparing action by dietary lipid 显示文摘 | NG W K ABDULLAH N DE SILVA S S | 2008 | Aquaculture2008，284，1234： | 1 |
| 6 | Ul- traviolet radiation enhanced growth of lactobacilli andtheir bioconversion of isoflavones in biotin - supple- mented soymilk 显示文摘 | Ewe J A Wan Abdullah W N Alias A K | 2013 | LWT - Food Science and Tech- nology2013，50，1： | 1 |
| 7 | Molecular charaemrization of a new 1-deoxy-D- xylulose 5-phosphate reductoisomerase (DXR) transcript from Vanda Mimi Palmer显示文摘 | CHAN W S ABDULLAH J O NAMASIVAYAM P | 2009 | Scientia Horticulture2009，121，： | 1 |
| 8 | Effects of feeding high forage diets and supplemental fat on feed intake and lactation per- formance in dairy cows 显示文摘 | Abdullah M Young J W Tyler H D | 2000 | Asian-Aust J Anita Sci2000，13，4： | 1 |
| 9 | Effects of ultrasound on growth, bioconversion of isoflavones and probiotic properties of parent and subsequent passages of Lactobacillus fermentum BT 8633 in biotin - supplemented soymilk 显示文摘 | Ewe J A Wan Abdullah W N Alias A K | 2012 | Ultrason- ics Sonochemistry2012，19，4： | 1 |
| 10 | Urban soil pollution inDamascus, Syria: concentrations and patterns of heavy metals in thesoils of the Damascus显示文摘 | Moller A Muller H W Abdullah A | 2005 | Ghouta Geoderma2005，124，12： | 1 |
| 11 | Growth performance,intestinal microbial populations,and serum cholesterol of broilers fed diets containing lactobacillus cultures显示文摘 | Jin L Z Ho Y W Abdullah N | 1998 | Poultry Science1998，77，9： | 1 |
| 12 | A Comprehensive Study of Data Collection Schemes Using Mobile Sinks in Wireless Sensor Networks显示文摘 | Khan A W Abdullah A H Anisi M H | 2014 | Sensors2014，14，2： | 1 |
| 13 | Effects of common inorganic anoins on rates of photocatalytic oxidation of organic carbon over illuminated显示文摘 | Abdullah Mohammad Low Gary K-C Matthews Ralph W | 1990 | Journal of Physical Chemistry1990，94，17： | 1 |
| 14 | Growth performance, intestinal microbial populations, and serum cholesterol of broilers fed diets containing Lactobacillus cultures显示文摘 | Jin L Z Ho Y W Abdullah N | 1998 | Poultry science1998，77，9： | 1 |
| 15 | Urban soil pollution in Damascus,Syria:Concentrations and patterns of heavy metals in the soils of the Damascus Ghouta显示文摘 | Moller A Muller H W Abdullah A | 2005 | Geoderma2005，124，12： | 1 |
| 16 | En- hanced growth of lactobacilli and bioconversion of isoflavones in biotin - supplemented soymilk upon ultrasound - treatment 显示文摘 | Ewe J A Wan Abdullah W N Bhat R | 2012 | Ultrasonics Sonochemis- try2012，19，1： | 1 |
| 17 | Influence of aggregate type and gradation on voids of asphalt concrete pavements显示文摘 | Abdullah W S Obaidat M T Abu-Sada N M | 1998 | Journal of Materials in Civil Engineering1998，10，2： | 1 |
| 18 | Multi-objective optimization using genetic algorithms:a tutorial显示文摘 | Abdullah Konakk Coit D W Smith A E | 2006 | Reliability Engineering and System Safety2006，91，9： | 1 |
| 19 | Organic geochemical characteristics and depositional environment of the Tertiary Tanjong Formation coals in the Pinangah area, onshore Sabah, Malaysia 显示文摘 | Alias F L Abdullah W H Hakimi M H | 2012 | International Journal of Coal Geology2012，104，： | 1 |
| 20 | Effects of ultrasound on growth, bioconversion of isoflavones and probiotic properties of parent and subsequent passages of Lactobacillus fermentum BT 8633 in biotin - supplemented soymilk 显示文摘 | Ewe J A Wan - abdullah W N Alias A K | 2012 | Ultrason Sonochem2012，19，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员