|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Protective effect of naringenin on acetic acid-induced ulcerative colitis in rats显示文摘AIM:To evaluate the ameliorative effect of naringenin(NG)during ulcerative colitis(UC)in rats.METHODS:Rats were treated with three different doses(25,50 and 100 mg/kg per day)of NG and a single dose of mesalazine(MES,300 mg/kg per day)for seven days prior to ulcerative colitis induction by4%acetic acid(AA).Twenty four hours after AA rectal administration,animals were scarified and the colonic tissues were dissected.Colonic mucus content was estimated using Alcian blue dye binding technique.In colon tissues,levels of total glutathione sulphadryls(T-GSH),non-protein sulphadryls(NP-SH)and thiobarbituric acid reactive substances(TBARS)were evaluated.The activities of the antioxidant enzymes,catalase(CAT)and superoxide dismutase(SOD)were measured.Concentrations of nucleic acids(DNA and RNA)and total protein were also estimated in colon tissues.Colonic levels of tumor necrosis factor-(TNF-),interleukin-1(IL-1),interleukin-6(IL-6),prostaglandin E2(PGE2)and nitric oxide(NO)were estimated.In cross section of colitis tissue the histopathological changes were observed.RESULTS:Colonic mucus content was decreased in AA compared to controls(587.09±65.59 mg/kg vs941.78±68.41 mg/kg,P<0.001).AA administration markedly reduced T-GSH(5.25±0.37 nmol/L vs 3.04±0.24 nmol/L,P<0.01),NP-SH(3.16±0.04 nmol/L vs 2.16±0.30 nmol/L,P<0.01),CAT(6.77±0.40 U/mg vs 3.04±0.2 U/mg,P<0.01)and SOD(3.10±0.11U/mg vs 1.77±0.18 U/mg,P<0.01)while TBARS,TNF-,IL-1,IL-6,PGE2 and NO levels(15.09±3.84nmol/L vs 59.90±16.34 nmol/L,P<0.01;113.56±1.91 pg/mg vs 134.24±4.77 pg/mg,P<0.01;209.20±36.38 pg/mg vs 422.19±31.47 pg/mg,P<0.01;250.83±25.09 pg/mg vs 638.58±115.9 pg/mg,P<0.01;248.19±36.98 pg/mg vs 541.74±58.34 pg/mg,P<0.01 and 81.26±2.98 mmol/g vs 101.90±10.73 mmol/g,P<0.001)were increased in colon of rats with UC compared controls respectively.Naringenin supplementation,significantly and dose dependently increased the colonic mucus content.The elevated TBARS levels were significantly decreased(39.35±5.86nmol/L,P<0.05;26.74±3.17 nmol/L,P<0.01 nmol/L and 17.74±2.69 nmol/L,P<0.01)compared to AA(59.90±16.34 nmol/L)group while the decreased levels of T-GSH and NP-SH and activities of CAT and SOD found increased by NG treatments in dose dependent manner.The decreased values of nucleic acids and total protein in AA group were also significantly(P<0.01)increased in all three NG supplemented groupsrespectively.NG pretreatment inhibited the TNF-levels(123.76±3.76 pg/mg,122.62±3.41 pg/mg and121.51±2.61 pg/mg vs 134.24±4.78 pg/mg,P<0.05)compared to AA group,respectively.Interleukins,IL-1 and IL-6 levels were also decreased in NG50+AA(314.37±16.31 pg/mg and 292.58±23.68 pg/mg,P<0.05)and NG100+AA(416.72±49.62 pg/mg and 407.96±43.87 pg/mg,P<0.05)when compared to AA(352.46±8.58 pg/mg and 638.58±115.98pg/mg)group.Similar decrease(P<0.05)was seen in PGE2and NO values when compared to AA group.The group pretreated with MES,as a reference drug,showed significant(P<0.01)protection against the changes induced in colon tissue by AA administration respectively.CONCLUSION:In present study,NG produced antioxidant and anti-inflammatory effects demonstrating protective effect in inflammatory bowel disease. | Salim S Al-Rejaie Hatem M Abuohashish Maher M Al-Enazi Abdullah H Al-Assaf Mihir Y Parmar Mohammed M Ahmed | 2013 | World Journal of Gastroenterology2013，19，34： | 20 |
| 2 | Gadolinium doped tin dioxide nanoparticles: an efficient visible light active photocatalyst显示文摘Photocatalytic degradation of phenol with sol-gel prepared rare earth doped tin dioxide(SnO_2) nanoparticles was reported.Gadolinium doped tin dioxide(SnO_2:Gd) nanoparticles were found to absorb higher visible light compared to lanthanum,neodymium and cerium doped materials that were studied in detail.Photocatalytic degradation of phenol under artificial white light and sunlight in the presence of SnO_2:Gd nanoparticles was studied with high performance liquid chromatography(HPLC),capillary electrophoresis(CE),total organic carbon(TOC) measurements and the determination of chemical oxygen demand(COD).Clear correlations between the results obtained from these multiple measurements were found,and a kinetic pathway for the degradation process was proposed.Within 150 min of solar irradiation,the TOC of a 10 ppm phenol solution in water was reduced by 95%-99%,thus demonstrating that SnO_2:Gd nanoparticles are efficient visible light photocatalysts. | Abdullah M Al-Hamdi Mika Sillanp?? Joydeep Dutta | 2015 | Journal of Rare Earths2015，33，12： | 5 |
| 3 | 氮化硼纳米片吸附Cd(Ⅱ)的动力学和热力学研究显示文摘本工作对Cd(Ⅱ)在多孔六方氮化硼(p-BN)上的吸附行为和机理进行了系统而全面的研究,考察了溶液pH、吸附剂用量、接触时间和温度等条件对于Cd(Ⅱ)吸附的影响,并采用不同手段表征了吸附前后p-BN的化学组成、形态和表面官能团的变化,进而研究其吸附机理。研究结果显示,在pH 7.0和313 K条件下, Cd(Ⅱ)的最大吸附容量可达到184mg·g–1,其动力学数据与拟二级模型和颗粒内扩散模型吻合,表明吸附主要受化学吸附控制,限速步骤主要是分子扩散。Cd(Ⅱ)在p-BN上的吸附是一个自发和吸热过程,吸附等温线分别符合Freundlich和Langmuir模型,说明Cd(Ⅱ)通过多层和单层吸附而吸附在非均相表面上。XPS的光谱结果显示,p-BN吸附剂具有大量的B–N,B–O等结构用作键合位点,有利于从废水中吸收Cd(Ⅱ)。这些结果表明, p-BN有希望作为吸附材料用于清除水体中的Cd(Ⅱ)。 | 李丽 郭筱洁 金阳 陈朝贵 Abdullah M Asiri Hadi M Marwani 赵轻舟 盛国栋 | 2020 | 无机材料学报2020，35，3： | 3 |
| 4 | The impact of ipsilateral testicular atrophy on semen quality and sperm DNA fragmentation response to varicocele repair显示文摘Varicoceles adversely impact semen quality and sperm DNA fragmentation,which typically improve with surgical repair.Some men with varicoceles have ipsilateral testicular atrophy due to damage from the varicocele.This study assessed semen quality and the sperm DNA fragmentation index(DFI)response to varicocele repair in men with ipsilateral testicular atrophy(TA)versus men with no testicular atrophy(NTA).Semen parameter values and DFI in both groups were compared preoperatively and postoperatively.The Mann-Whitney U test and the Wilcoxon signed-rank test were used where appropriate.There were 20 men in the TA group and 121 men in the NTA group with no difference in age,varicocele grade,or preoperative semen parameter values between the two groups.The NTA group had a higher preoperative DFI than the TA group.Both groups showed improvement in semen quality postoperatively,only the TA group showed a significant improvement in DFI,whereas the NTA group showed significant improvements in several parameter values and DFI.The change from preoperative to postoperative parameter values when comparing the two groups revealed a difference in total sperm motile count and DFI,with a larger mean improvement in the NTA group than in the TA group.Both TA and NTA groups showed improved semen quality and DFI after varicocele repair,but the NTA group had more improvement than the TA group.However,only total motile count(TMC)and DFI had a significantly greater mean change in preoperative to postoperative response in the NTA group than in the TA group. | Parviz K Kavoussi Natasha Abdullah Melissa S Gilkey Caitlin Hunn G Luke Machen Shu-Hung Chen Keikhosrow M Kavoussi Amy Esqueda J David Wininger Shahryar K Kavoussi | 2021 | Asian Journal of Andrology2021，23，2： | 2 |
| 5 | Breaking wheat yield barriers requires integrated efforts in developing countries显示文摘Most yield progress obtained through the so called 'Green Revolution', particularly in the irrigated areas of Asia, has reached a limit, and major resistance genes are quickly overcome by the appearance of new strains of disease causing organisms.New plant stresses due to a changing environment are difficult to breed for as quickly as the changes occur.There is consequently a continual need for new research programs and breeding strategies aimed at improving yield potential, abiotic stress tolerance and resistance to new, major pests and diseases.Recent advances in plant breeding encompass novel methods of expanding genetic variability and selecting for recombinants, including the development of synthetic hexaploid, hybrid and transgenic wheats.In addition, the use of molecular approaches such as quantitative trait locus(QTL) and association mapping may increase the possibility of directly selecting positive chromosomal regions linked with natural variation for grain yield and stress resistance.The present article reviews the potential contribution of these new approaches and tools to the improvement of wheat yield in farmer's fields, with a special emphasis on the Asian countries, which are major wheat producers, and contain the highest concentration of resource-poor wheat farmers. | Saeed Rauf Maria Zaharieva Marilyn L Warburton ZHANG Ping-zhi Abdullah M AL-Sadi Farghama Khalil Marcin Kozak Sultan A Tariq | 2015 | Journal of Integrative Agriculture2015，14，8： | 2 |
| 6 | Anticoagulation and antiplatelets as prophylaxis for hepatic artery thrombosis after liver transplantation显示文摘Hepatic artery thrombosis(HAT) is the most serious vascular complication after liver transplantation. Multiple risk factors have been identified to impact its development. Changes in haemostasis associated with end stage liver disease and the disturbance of the coagulation and anticoagulation cascades play an important role in development of this lethal complication. Early recognition and therapeutic intervention is mandatory to avoid its consequences. Pharmacological prophylaxis, by the use of antiplatelet or anticoagulant agents, is an important tool to reduce its incidence and prevent graft loss. Only a few studies have shown a clear benefit of antiplatelet agents in reducing HAT occurrence, however, these studies are limited by being retrospective and by inhomogeneous populations. The use of anticoagulants such as heparin is associated with an improvement in the outcomes mainly when used for a high-risk patients like living related liver recipients. The major concern when using these agents is the tendency to increase bleeding complications in a setting of already unstable haemostasis. Hence, monitoring of their administration and careful selection of patients to be treated are of great importance. Well-designed clinical studies are still needed to further explore their effects and to formulate proper protocols that can be implemented safely. | Abdullah A Algarni Moustafa M Mourad Simon R Bramhall | 2015 | World Journal of Hepatology2015，7，9： | 2 |
| 7 | Low speed calibration of hot-wire anemometers 显示文摘 | Abdullah M AL-Gami | 2007 | Flow Measure and Instrument2007，18，： | 1 |
| 8 | Reverse en-gineering of turbine blades based on design intent 显示文摘 | Mohaghegh K Sadeghi M H Abdullah A | 2007 | International Journal of Advanced Manufacturing Tech-nology2007，32，5： | 1 |
| 9 | Application of flexible printed circuit board (FPCB) in personal computer motherboards: Focusing on mechanical performance 显示文摘 | LEONG W ABDULLAH M KHOR C | 2012 | Microelectronics Reliability2012，52，4： | 1 |
| 10 | Tensile Testing for Weld Properties in Tailor Welded Blanks Using the Rule of Mixtures显示文摘 | Abdullah K Wild P M Jeswiet J J | | 0，，： | 1 |
| 11 | Frequency Domain Identifica- tion of Transfer Function Model of a Disk Drive Actuator显示文摘 | ABDULLAH A M LEE T H | 2002 | Mechatronics2002，，12： | 1 |
| 12 | A survey on routing techniques in underwater wireless sensor networks显示文摘 | Ayaz M Nubaig I Abdullah A | 2011 | Journal of Network and Computer Application2011，34，6： | 1 |
| 13 | Elec- tromigration noise measurements using a novel AC/DC water -level noise measurement system 显示文摘 | ABDULLAH M Y CHARLES I' CHEN Songming | 1997 | IEEE Transactions on Electron Devices1997，44，1： | 1 |
| 14 | The effect of storage temperature on histamine production and the freshness of yellowfin tuna(Thunnus albacares)显示文摘 | Guizani N Abdullah M Busaidy A | 2005 | Food Research International2005，38，2： | 1 |
| 15 | Heavy metals (Cd, Cu, Cr, Pb and Zn) in Meretrix meretrix roding, water and sediments from estuaries in sabah, North Borneo显示文摘 | ABDULLAH M H SIDI J ARIS A Z | 2007 | International Journal of Environmental & Science Education2007，2，3： | 1 |
| 16 | Optimal placement of DVFC controllers on buildings subjected to earthquake loading显示文摘 | Abdullah M | 1999 | Earthquake Engineering and Structural Dynamics1999，28，2： | 1 |
| 17 | Improvement of reverse-engineered turbine blades using construction geometry 显示文摘 | MOHAGHEGH K SADEGHI M ABDULLAH A | 2010 | International Journal of Advanced Manufacturing Technology2010，49，58： | 1 |
| 18 | Substitution of nitrite by sorbate and the effect on properties of mortadella 显示文摘 | A1- Shuibi A M B M M- Abdullah | 2002 | Meat Science2002，62，4： | 1 |
| 19 | Microwave electromagnetic and absorption properties of some LiZn ferrites 显示文摘 | YUSOFF N ABDULLAH M H | 2004 | J Magn Magn Mater2004，269，： | 1 |
| 20 | Placement of sensors/actuators on civil structures using genetic algorithms显示文摘 | Abdullah M Richardson A Hanif J | 2001 | Earthquake Engineering and Structural Dynamics2001，30，8： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员