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| 1 | LHP1 Interacts with ATRX through Plant-Specific Domains at Specific Loci Targeted by PRC2显示文摘(HP1 ) Heterochromatin 蛋白质 1 是染色质结构和功能的一个主要管理者。在动物,与 HP1 交往的蛋白质的网络主要与组成的 heterochromatin 由 H3K9me3 标记被联系。HP1 身体上与 SNF2 染色质 remodeler ATRX 的通常认为的 ortholog ?交往,它在哺乳动物控制 histone 变体 H3.3 的免职。在这研究,我们证明 ATRX 的 Arabidopsis thaliana ortholog ?参予 H3.3 免职并且在植物拥有特定的保存领域。我们发现象 HP1 (LHP1 ) 蛋白质一样的那植物通过在陆地植物明确地演变的领域与 ATRX 交往 ? 祖先。在 Arabidopsis 的 ATRX 功能的损失影响 PRC2 (POLYCOMB 压抑的建筑群 2 ) 控制的基因的一个有限子集的表示,包括 flowering 时间管理者 FLC。在 flowering 时间的规定的 ATRX 的函数要求新奇交往 LHP1 领域和 ATRX SNF2 helicase 域的 ATPase 活动。一起拿,这些结果建议不同进化小径在植物在哺乳动物和它的对应物 LHP1 导致了在 ATRX 和 HP1 之间的相互作用,导致 transcriptional 的不同模式规定。 | Haifeng Wang Danhua Jiang Elin Axelsson Zdravko J. Lorkovic Sean Montgomery Sarah Holec Bas J.G.E. Pieters Abbas H.K. AI Temimi Jasmin Mecinovic Frederic Berger | 2018 | Molecular Plant2018，11，8： | 3 |
| 2 | Functional evaluation of the filtering bleb by ultrasound biomicroscopy after trabeculectomy with mitomycin C显示文摘AIM: To study the role of ultrasound biomicroscopy(UBM) in the assessment of the bleb function after trabeculectomy with mitomycin C(MMC). METHODS: This was a cross-sectional study including all cases had undergone trabeculectomy with MMC 0.2 mg/mL for 3 min. Participants were recruited from the follow-up cases at Department of Ophthalmology, Tanta University in the period from August 2015 to August 2016. Full history taking and ophthalmological examination were performed. Intraocular pressure(IOP) was measured using Goldmann applanation tonometry and the history of prescribed postoperative antiglaucoma medications was recorded. Accordingly, the trabeculectomy blebs were divided clinically into successful blebs when the IOP post-operative was ≤18 mmHg without medications. Scanning examination of the filtering bleb using UBM examination was performed at the period from 2 to 36 mo after trabeculectomy(13.6±9.7 m o). RESULTS: This study included 33 trabeculectomy filtering blebs of 25 patients(9 males and 16 females). The mean age of patients was 53.2±14.2 y(range 25-71y). We had 20 eyes with complete success, 9 eyes with qualified success, and 4 eyes with failure after trabeculectomy with MMC. The blebs were classified into successful blebs(IOP ≤18 mmHg without antiglaucoma medications), others were classified into qualified successful and failed blebs. There was a significant correlation between certain UBM findings(intra-bleb reflectivity, draining sub-scleral tract, bleb height, and intrableb fluid cysts) and cases with different grades of clinical functional success(P<0.01).CONCLUSION: UBM is an objective tool in the functional assessment of the post-trabeculectomy filtering bleb through a significant correlation between certain UBM parameters and the different grades of clinical functional success. | Ali Abbas El Salhy Rabab Mohamed Elseht Ahmed Fekry AI Maria Saied Mohamed Abd El-wahab Shalaby Tarek Ragaee Hossein | 2018 | International Journal of Ophthalmology(English edition)2018，11，2： | 3 |
| 3 | Amisulpride is a potent 5-HT7 antagonist: relevance for antidepressant actions in vivo 显示文摘 | Abbas AI Hedlund PB Huang XP | 2009 | J Psychopharmacol (Bed)2009，205，1： | 1 |
| 4 | Predicting new molecular targets for known drugs显示文摘 | Keiser MJ Setola V Irwin JJ Laggner C Abbas AI Hufeisen SJ | | 0，，7270： | 1 |
| 5 | Amisulpride is a potent 5- H37 antagonist:relevance for antidepressant actions in vivo显示文摘 | Abbas AI Hedlund PB Huang XP | 2009 | J Psy- chopharmacol ( Berl )2009，205，： | 1 |
| 6 | Woleott - Rallison syn- drome in two siblings with isolated central hypothyroidism显示文摘 | Bin - Abbas B AI - Mulhim A A1 - Ashwal A | 2002 | Am J Med Genet2002，111，2： | 1 |
| 7 | Immunophenotypic characterization of peripheral T lymphocytes in pulmonary tuberculosis 显示文摘 | AI Majid FM Abba AA | 2008 | J Postgrad Med2008，54，1： | 1 |
| 8 | Spectra of normal and nutrient deficient maize leaves 显示文摘 | AI - Abbas A H Barr R Hall J D | 1974 | Agronomy Journal1974，66，： | 1 |
| 9 | Amisulpride is a potent 5-HT7 antagonist:relevance for antidepressant actions in vivo显示文摘 | Abbas AI Hedlund PB Huang XP | 2009 | Psychopharmacology(Berl)2009，205，1： | 1 |
| 10 | Amisulpride is a potent 5-HT7antagonist:relevance for antidepressant actions in vivo显示文摘 | Abbas AI Hedlund PB Huang XP | 2009 | Psychopharmacology2009，205，1： | 1 |
| 11 | Amisulpride is a potent 5-HT7 antagonist:relevance for antidepressant actions in vivo显示文摘 | Abbas AI Hedlund PB Huang XP | | 0，，01： | 1 |
| 12 | Fetal renal defects:associated malformatfons and chromosomai defects显示文摘 | Nfcolaides KH Oheng HH Abbas A et aI | | Fetal Diagn Ther 9920，7，1： | 1 |
| 13 | Conservative versus radical surgery for treatment of uncomplicated hepatic hydatid cysts显示文摘 | Abbas M Nafeh AI Youssef YF | 2006 | J Egypt Soc Parasitol2006，36，2： | 1 |
| 14 | Amisulpride is a potent 5-HT7 antagonist: relevance for antidepressant actions in vivo 显示文摘 | Abbas AI Hedlund PB Huang XP | 2009 | J Psychopharmacol ( Berl )2009，205，1： | 1 |
| 15 | Comparative performance evaluation of conventional bleaching and enzymatic blea- ching with glucose oxidase on knitted cotton fabric显示文摘 | Farooq A Ali S Abbas N et aI | 2013 | Journal of Cleaner Production2013，42，： | 1 |
| 16 | Subclinical hypothyroidism is associated with early insulin resistance in Kuwaiti women显示文摘 | AI Sayed A AI Ali N Bo Abbas Y | 2006 | Endocr J2006，53，5： | 1 |
| 17 | Mice with altered serotonin 2C receptor RNA editing display characteristics of Prader-Willi syndrome显示文摘 | Morabito MV Abbas AI Hood JL | 2010 | Neurobiol Dis2010，39，2： | 1 |
| 18 | Amisulpride is a potent 5- I-IT 7 antagonist: relevance for antidepressant actions in vivo 显示文摘 | Abbas AI Hedlund PB Huang XP | 2009 | Psychopharmacology2009，205，1： | 1 |
| 19 | H1F-1 ~Overexpression Induces Angiogenesis in Mesenchymal StemCells 显示文摘 | Vahid Razban Abbas Sahebqadam Lotfi Masoud Soleimani et aI | 2012 | BioresearchOpenAccess2012，1，4： | 1 |
| 20 | Predicting new molecular targets for known drugs 显示文摘 | Keiser MJ Setola V Irwin JJ Laggner C Abbas AI Hufeisen SJ | 2009 | Na- ture2009，462，7270： | 1 |
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