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| 1 | Bipolar transurethral enucleation and resection of the prostate:Whether it is ready to supersede TURP?显示文摘Objective:According to the EAU Guidelines,transurethral resection of the prostate(TURP)has so far still been considered as the gold standard for surgical treatment for patients with obstructing clinical benign prostate hyperplasia(BPH).However,its relatively high rate of complications and postoperative recurrence necessitates further modification and innovation on the surgery technique.We reported the patient outcomes with our technique.Methods:We retrospectively analyzed 52 patients with obstructing clinical BPH who underwent bipolar transurethral enucleation and resection of the prostate(B-TUERP)between March 2015 and September 2015.Pre-and perioperative parameters were obtained from medical charts.Postoperative follow-ups were administrated at 1,3,6,12 and 24 month(s)after surgery,respectively.Results:All the operations were performed successfully with a mean operative time of 43.1 min and an average tissue removal rate of 74.7%.Qmax was significantly improved immediately after surgery,followed by a continuous improvement throughout the follow-ups.Following a steep decrease in mean prostate specific antigen(PSA)and post void residual(PVR)observed within the first half year after surgery,the serum PSA was then maintained at a constant level of 0.61 ng/mL.Temporary urinary retention was found in four cases(7.7%).Stress urinary incontinence occurred in five patients(9.6%),with the condition resolved in 1e2 weeks without extra treatment.Urethral strictures and bladder neck contractures,as the most commonly observed long-term complications,developed in four patients(7.7%).No recurrence was found during 2 years of follow-ups.An improvement in International Index of Erectile Function(IIEF-5)scores was witnessed in 17 patients preoperatively with normal sexual function during the first 6 months after surgery,and sustained throughout the 24-month period.Conclusions:Enucleation reflects an improvement on surgical technique in many ways with a need for surgical equipment that can be broadly accessible in clinical practice.Currently,bipolar resection is a commonly employed procedure in clinical settings,and its similarity shared with bipolar enucleation technique warrants a quick learning of B-TUERP by urologists.Based on these findings,we believe that the substitution of TURP by TUERP as the gold standard for prostate endoscopic procedure can be expected in the future. | Peng Xu Abai Xu Binshen Chen Shaobo Zheng Yawen Xu Hulin Li Haiyan Shen Chunxiao Liu | 2018 | Asian Journal of Urology2018，5，1： | 19 |
| 2 | Melatonin enhances radiofrequency-induced NK antitumor immunity,causing cancer metabolism reprogramming and inhibition of multiple pulmonary tumor development显示文摘Surgery is the comm on treatme nt for early lung cancer with multiple pulm onary no dules,but it is often accompanied by the problem of significant malignancy of other nodules in non-therapeutic areas.In this study,we found that a combined treatment of local rad iofreq ue ncy ablati on(RFA)and melatonin(MLT)greatly improved clinical outcomes for early lung cancer patie nts with multiple pulmonary nodules by minimizing lung function injury and reducing the probability of malignant transformation or enlargement of nodules in non-ablated areas.Mechanically,as demonstrated in an associated mouse lung tumor model,RFA not only effectively remove treated tumors but also stimulate antitumor immunity,which could inhibit tumor growth in non-ablated areas.MLT enhanced RFA-stimulated NK activity and exerted synergistic antitumor effects with RFA.Transcriptomics and proteomics analyses of residual tumor tissues revealed enhanced oxidative phosphorylation and reduced acidification as well as hypoxia in the tumor microenvironment,which suggests reprogrammed tumor metabolism after combined treatment with RFA and MLT.Analysis of residual tumor further revealed the depressed activity of MAPK,NF-kappa B,Wnt,and Hedgehog pathways and upregulated P53 pathway in tumors,which was in line with the inhibited tumor growth.Combined RFA and MLT treatment also reversed the Warburg effect and decreased tumor malignancy.These findings thus demonstrated that combined treatment of RFA and MLT effectively inhibited the malignancy of non-ablated nodules and provided an innovative non-invasive strategy for treating early lung tumors with multiple pulmonary nodules.Trial registration:www.chictr.org.cn,identifier ChiCTR2100042695,http://gffzz62a03ee25e6f4a77h9w059uoxn6o06fnn.ffgz.tsg.suse.edu.cn/showproj.aspx?proj=120931. | Ming Li Bingjie Hao Menghuan Zhang Russel J.Reiter Shumeng Lin Tiansheng Zheng Xiangyun Chen Yanbei Ren Liduo Yue Baigenzhin Abay Guojie Chen Xiao Xu Yufeng Shi Lihong Fan | 2021 | Signal Transduction and Targeted Therapy2021，6，10： | 6 |
| 3 | Current and future predicting potential areas of Oxytenanthera abyssinica(A.Richard)using MaxEnt model under climate change in Northern Ethiopia显示文摘Introduction:Climate change will either improve,reduce,or shift its appropriate climatic habitat of a particular species,which could result in shifts from its geographical range.Predicting the potential distribution through MaxEnt modeling has been developed as an appropriate tool for assessing habitat distribution and resource conservation to protect bamboo species.Methods:Our objective is to model the current and future distribution of Oxytenanthera abyssinica(A.Richard)based on three representative concentration pathways(RCP)(RCP2.6,RCP4.5,and RCP8.5)for 2050s and 2070s using a maximum entropy model(MaxEnt)in Northern Ethiopia.For modeling procedure,77 occurrence records and 11 variables were retained to simulate the current and future distributions of Oxytenanthera abyssinica in Northern Ethiopia.To evaluate the performance of the model,the area under the receiver operating characteristic(ROC)curve(AUC)was used.Results:All of the AUCs(area under curves)were greater than 0.900,thereby placing these models in the“excellent”category.The jackknife test also showed that precipitation of the coldest quarter(Bio19)and precipitation of the warmest quarter(Bio18)contributed 66.8%and 54.7%to the model.From the area of current distribution,1367.51 km2(2.52%),7226.28 km2(13.29%),and 5377.26 km2(9.89%)of the study area were recognized as high,good,and moderate potential habitats of Oxytenanthera abyssinica in Northern Ethiopia,and the high potential area was mainly concentrated in Tanqua Abergele(0.70%),Kola Temben(0.65%),Tselemti(0.60%),and Tsegede(0.31%).Kafta Humera was also the largest good potential area,which accounts for 2.75%.Compared to the current distribution,the total area of the high potential regions and good potential regions for Oxytenanthera abyssinica under the three RCPs(RCP2.6,RCP4.5,and RCP8.5)would increase in the 2050s and 2070s.However,the total area of the least potential regions under the three RCPs(RCP2.6,RCP4.5,and RCP8.5)in 2050s and 2070s would decrease.Conclusion:This study can provide vital information for the protection,management,and sustainable use of Oxytenanthera abyssinica,the resource to address the global climate challenges. | Yikunoamlak Gebrewahid Selemawi Abrehe Esayas Meresa Gebru Eyasu Kiros Abay Gebrehiwot Gebreab Kiros Kidanemariam Gezu Adissu Gebrekidan Abreha Girmay Darcha | 2020 | Ecological Processes2020，9，1： | 4 |
| 4 | Phlebotomus papatasi and Meriones libycus as the vector and reservoir host of cutaneous leishmaniasis in Qomrood District,Qom Province,central Iran显示文摘Objective:To determine the sand flies species responsible for most transmission of Leishmania major(L major) to human,as well as to determine the main reservoir hosts of the disease. Methods:Sand flies were collected using sticky papers and mounted in Puri’s medium for species identification.Rodents were trapped by live Sherman traps.Both sand flies and rodents were subjected to molecular methods for detection of leishmanial parasite.Results:Phlebotomus papatasi(P.papatasi) was the common species in outdoor and indoor resting places.Employing PCR technique only three specimens of 150 P.papatasi(2%) were found naturally infected by parasites with a band of 350 bp which is equal to the L major parasite.Forty six rodents were captured by Sherman traps and identified.Microscopic investigation on blood smear of the animals for amastigote parasites revealed 1(3.22%) infected Meriones libycus(M.libycus). Infection of this animal to L.major was confirmed by PCR against rDNA loci of the parasite. Conclusions:This is the first molecular report of parasite infection of both vector(P.papatasi) and reservoir(M.libycus) to L major in the region.The results indicated that P.papatasi was the primary vector of the disease and circulating the parasite between human and reservoirs and M. libycus was the most important host reservoir for maintenance of the parasite source in the area. | Rassi Yavar Saghafipour Abedin Abai Mohammad Reza Oshaghi Mohammad Ali Rafizadeh Sina Mohebail Mehdi Yaaghobi-Ershadi Mohammad Reza Mohtarami Fatemeh Farzinnia Babak | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，2： | 3 |
| 5 | Climate change and potential distribution of zoonotic cutaneous leishmaniasis in Central Iran: Horizon 2030 and 2050显示文摘Objective: To investigate and predict the effects of climate change on the potential distribution of the main vector and reservoir hosts of the disease in Yazd province in the future.Methods: Distribution data for vector and reservoir hosts of zoonotic cutaneous leishmaniasis in Yazd province were obtained from earlier studies conducted in the area.MaxEnt ecological niche modeling was used to predict environmental suitability.BCC-CSM1-1(m) model and two climate change scenarios, RCP 4.5 and RCP 8.5 were used for horizons 2030 and 2050 climate projections.Future projections were based on data of a regional climate change model.Results: With both scenarios in 2030 and 2050, the results of jackknife test indicated that the mean temperature of wettest quarter and temperature annual range had the greatest effect on the model for the vector and the reservoir hosts, respectively.Conclusions: The climate conditions are the major determinants of zoonotic cutaneous leishmaniasis incidence rate in Yazd Province.These climate conditions provide favorable habitats for ease transmission of zoonotic cutaneous leishmaniasis in this endemic area.Habitats suitability for the vector and reservoir will be expanding in the coming years compared with the current conditions, such that, in horizon 2030 & 2050, the probability of the presence of the vector and reservoir within 38 580 and 37 949 km^2, respectively, from Yazd province is above 60%.Moreover, an increase is predicted in the presence of the vector in the western parts and the reservoir in the northern and central parts of the province in the future.Understanding the role of environmental and bioclimatic factors in zoonotic cutaneous leishmaniasis occurrence can provide a guide for policy-makers in the creation and implementation of more effective policies for prevention and control. | Babak Shiravand Ahmad Ali Hanafi-Bojd Abbas Ali Dehghani Tafti Mohammad Reza Abai Ali Almodarresi Masoud Mirzaei | 2019 | Asian Pacific Journal of Tropical Medicine2019，12，5： | 2 |
| 6 | Anopheline species composition in borderline of Iran–Azerbaijan显示文摘 | M.A. Oshaghi H. Vatandoost A. Gorouhi M.R. Abai A. Madjidpour S. Arshi H. Sadeghi M. Nazari A. Mehravaran | 2011 | Acta Tropica2011，，1： | 2 |
| 7 | Bioinspired and biomimetic membranes for water purification and chemical separation: A review显示文摘Bioinspired and biomimetic membranes that contain biological transport channels or attain their structural designs from biological systems have been through a remarkable development over the last two decades.They take advantage of the exceptional transport properties of those channels,thus possess both high permeability and selectivity,and have emerged as a promising solution to existing membranes.Since the discovery of biological water channel proteins aquaporins(AQPs),extensive efforts have been made to utilize them to make separation membranes–AQP-based membranes,which have been commercialized.The exploration of AQPs’unique structures and transport properties has resulted in the evolution of biomimetic separation materials from protein-based to artificial channelbased membranes.However,large-scale,defect-free biomimetic membranes are not available yet.This paper reviews the state-of-the-art biomimetic membranes and summarizes the latest research progress,platform,and methodology.Then it critically discusses the potential routes of this emerging area toward scalable applications.We conclude that an appropriate combination of bioinspired concepts and molecular engineering with mature polymer industry may lead to scalable polymeric membranes with intrinsic selective channels,which will gain the merit of both desired selectivity and scalability. | Elham Abaie Limeimei Xu Yue-xiao Shen | 2021 | Frontiers of Environmental Science & Engineering2021，15，6： | 2 |
| 8 | Phytochemistry and larvicidal activity of Eucalyptus camaldulensis against malaria vector,Anopheles stephensi显示文摘Objective:To determine phytochemistry and larvicidal activity of Eucalyptus eamaldulensis against Anopheles stephensi.Methods:The chemical compositions of the leaf essential oils were analyzed using gas chromatography/mass spectrometry(GC/MS).The larvicidal activity of essential oils and extract of leaf were tested against 4th instar larvae of laboratory-reared Anopheles stephensi.Results:GC/MS analyses identified the presence of 28 compounds corresponding to 99.60%of the total oil.The main constituents in the leaf essential oil were 1,8-cineole(69.46%),γ-Terpinene(15.10%),α-Pinene(5.47%) and Globulol(2%).The leaf extract and volatile oil exerted significant larvicidal activity with LC50 values of 89.85 and 397.75 ppm,respectively.Clear dose-response relationships were established with the highest dose of 320 ppm essential oil extract resulted almost 100%mortality in the population.Conclusions:The larvicidal properties suggest that the essential oil of plant is a potential source of valuable larvicidal compounds against malaria vector and can be used as an alternative to synthetic insecticides. | Sedaghat Mohamad Medhi Sanei Dehkordi Ali Reza Khnavi Mahnaz Abai Mohammad Reza Hadjiakhoondi Abbas Mohtarami Fatemeh Vatandoost Hassan | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，11： | 2 |
| 9 | 中哈特殊食药用菌的收集分离及功效评价显示文摘哈萨克斯坦有丰富的食药用菌资源,如牛肝菌、猴头菌、块菌、桦褐孔菌等,均具有很高的研究价值。山西气候和地形复杂多样,造就了丰富的特殊真菌资源,像五台山、芦芽山、中条山、太行山等独特的气候、丰富的植被条件以及特殊的生态环境,为大型真菌的生长繁殖提供了良好的环境。五台山的台蘑,芦芽山的银盘蘑菇,关帝山的羊肚菌,霍州的枝瑚菌,垣曲虫草,中条山的香棒虫草、块菌等都有很高的研究价值,均是药用及食用价值高的名优真菌。近几年我们对中哈两国特殊食药用菌资源进行了收集分离、液体培养及功效评价。 | 杨槐俊 郭素萍 Sagitov Abay | 2013 | 科技情报开发与经济2013，23，5： | 2 |
| 10 | Effects of Low Concentration Methanol, PVP and PVCap on Structure-I Methane Hydrate Formation显示文摘 | Wei Ke Thor M. Svartaas Hailu K. Abay | 2013 | Journal of Energy and Power Engineering2013，7，3： | 2 |
| 11 | Phenotypic and genotypicvariation in flowering time in Ethiopian barleys显示文摘 | Tsehaye Y Bj?rnstad ? Abay F | 2012 | Euphytica2012，188，3： | 1 |
| 12 | Novel microneutraliza- tion assay for HCMV using automated data collection and analysis显示文摘 | Abai A M Smith L R Wloch M K | 2007 | J Immunol Methods2007，322，12： | 1 |
| 13 | Traumatic axonal injury results in biphasic calpain activation and retrograde transport impairment in mice 显示文摘 | SAATMAN KE ABAI B GROSVENOR A | 2003 | J Cereb Blood Flow Metab2003，23，1： | 1 |
| 14 | Traumatic axonal injury results in biphasic calpain activation and retrograde transport impairment in mice 显示文摘 | Saatman K E Abai B Grosvenor A | 2003 | J Cereb Blood Flow Metab2003，23，1： | 1 |
| 15 | Repellency efects of essential oils of Myrtle (Myrtus communis), Marigold (Calendula offwinalis) compared with DEET against Anopheles stephensi onhuman volunteers显示文摘 | Tavasso|i M Shayeghi M Abai MR | 2011 | Iran J Arthropod-Bor2011，5，2： | 1 |
| 16 | Traumatic axonal injury results in biphasic calpain activation and retrograde transport impairmemt in mice显示文摘 | Saatman KE Abai B Grosvenor A | | 0，，： | 1 |
| 17 | Income inequality and the environment: aggregation bias in environmental Kuznets curves显示文摘 | Nico Heerink Abay Mulatu Erwin Bulte | 2001 | Ecological Economics2001，，3： | 1 |
| 18 | Income Inequality and the Environment: Aggregation Bias in Environmental Kuznets Curves显示文摘 | Nico H Abay M Erwin B | 2001 | Ecological Economics2001，58，5： | 1 |
| 19 | Larvicidal Activity of Essential Oils of Apiaceae Plants against Malaria Vector,Anopheles stephensi显示文摘 | SEDAGHAT M Ms DEHKORDI A S ABAI M R | 2011 | Iranian Journal of Arthropod-bome Diseases2011，5，2： | 1 |
| 20 | Income Inequality and the Environment: Aggregation Bias in Environmental Kuznets Crones显示文摘 | Nico Heerink Abay Mulatu Encin Buhe | 2001 | Ecological Economies2001，，38： | 1 |
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