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8篇 您的检索式:作者名="ATHOS J"
    题名 作者 年代 出处 被引量
1Correlation of endoscopic disease severity with pediatric ulcerative colitis activity index score in children and young adults with ulcerative colitis显示文摘AIM To investigate of pediatric ulcerative colitis activity index(PUCAI) in ulcerative colitis correlate with mucosal inflammation and endoscopic assessment of disease activity(Mayo endoscopic score).METHODS We reviewed charts from ulcerative colitis patients who had undergone both colonoscopy over 3 years. Clinical assessment of disease severity within 35 d(either before or after) the colonoscopy were included. Patients were excluded if they had significant therapeutic interventions(such as the start of corticosteroids or immunosuppressive agents) between the colonoscopy and the clinical assessment. Mayoendoscopic score of the rectum and sigmoid were done by two gastroenterologists. Inter-observer variability in Mayo score was assessed.RESULTS We identified 99 patients(53% female, 74% pancolitis) that met inclusion criteria. The indications for colonoscopy included ongoing disease activity(62%), consideration of medication change(10%), assessment of medication efficacy(14%), and cancer screening(14%). Based on PUCAI scores, 33% of patients were in remission, 39% had mild disease, 23% had moderate disease, and 4% had severe disease. There was 'moderate-substantial' agreement between the two reviewers in assessing rectal Mayo scores(kappa = 0.54, 95%CI: 0.41-0.68). CONCLUSION Endoscopic disease severity(Mayo score) assessed by reviewing photographs of pediatric colonoscopy has moderate inter-rater reliability, and agreement was less robust in assessing patients with mild disease activity. Endoscopic disease severity generally correlates with clinical disease severity as measured by PUCAI score. However, children with inflamed colons can have significant variation in their reported clinical symptoms. Thus, assessment of both clinical symptoms and endoscopic disease severity may be required in future clinical studies.Basavaraj Kerur Heather J Litman Julia Bender Stern Sarah Weber Jenifer R Lightdale Paul A Rufo Athos Bousvaros 2017World Journal of Gastroenterology2017,23,18:5
2Regulation of ovarian steroidogenesis in vitro by follicle stimulating hormone and luteinizing hormone during sexual maturation in salmonid fish显示文摘PIANSA J V ATHOS J SWANSON P 2000Biological Reproductive2000,62,5:1
3Regulation of ovarian steroidogenesis in vitro by follicle-stimulating hormone and luteinizing hormone during sexual maturation in salmonid fish 显示文摘Planas J V Athos J Goetz F W 2000Biology of Reproduction2000,62,5:1
4Variation in Care in Pediatric Crohn Disease显示文摘Richard B Colletti Robert N Baldassano David E Milov Peter A Margolis Athos Bousvaros Wallace V Crandall Karen D Crissinger Michael A D?Amico Andrew S Day Lee A Denson Marla Dubinsky Dawn R Ebach Edward J Hoffenberg Howard A Kader David J Keljo Ian H Leib 2009Journal of Pediatric Gastroenterology and Nutrition2009,,3:1
5Conversion of glycerol to 1,3-propanediol via selective dehydroxylation显示文摘Wang K Hawley M C De Athos S J 2003Industrial and Engineering Chemistry Research2003,42,13:1
6Calcium-stimulated adenylyl cyclase activity is critical for hippocampus dependent long-term memory and late phase LTP 显示文摘Wong S T Athos J Figueroa X A 1999Neuron1999,23,4:1
7Regulation of ovarian steroidogenesis in vitro by follicle stimulating hormone and luteinizing hormone during sexual maturation in salmonid fish显示文摘PIANAS J V ATHOS J SWANSON P 2000Biol Reprod2000,62,5:1
8破裂和未破裂颅内动脉瘤栓塞治疗实践标准显示文摘弹簧圈栓塞最初被设计并经美国食品药品监督管理局批准用于治疗显微外科手术夹闭风险高的脑动脉瘤,但目前该方法越来越被认为是颅内动脉瘤的一线治疗方法。动脉瘤血管内治疗技术已有长足进步,新器材的研发使得以前因血管解剖结构复杂而无法填塞的动脉瘤也得以治疗,从而扩大了血管内治疗的适应证。而且,血管内弹簧圈栓塞已成为当前动脉瘤血管内治疗的主流方法;医学文献证明,在特定患者人群中,弹簧圈栓塞的转归优于外科手术夹闭。最近的一份美国心脏协会(AmericanHeartAssociation,AHA)科学声明指出,对于适合治疗的脑动脉瘤,不论是血管内栓塞还是显微外科手术夹闭,均为破裂动脉瘤I级推荐治疗方法和未破裂动脉瘤的11a级推荐治疗方法。在这两组患者中,治疗利大于弊。一个在血管显微神经外科、神经重症监护和介入神经外科方面有着丰富经验的多学科团队最有利于对颅内动脉瘤的处理实施最佳的技术。神经血管联合写作组此前已发表过一份联合声明,提出了有关脑血管介入治疗的培训和认证的推荐意见。Athos Patsalides Ketan R Bulsara Daniel P Hsu Todd Abruzzo Sandm Narayanan Mahesh V Jayaraman Gary Duckwiler Richard Paul Klucznik Michael Kelly Joshua A Hirsch Don Heck Jeffery Stmshine Don Frei Michael J Alexander Huy M Do Philip M Meyers 邱忠明(译) 张君(译) 徐格林(译) 2013国际脑血管病杂志2013,21,6:0
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