|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Characterization and phylogenetic analysis of novel polyene type antimicrobial metabolite producing actinomycetes from marine sediments:Bay of Bengal India显示文摘Objective:To isolate and indentify the promising antimicrobial metabolite producing Streptomyces strains from marine sediment samples from Andraprudesh coast of India.Methods:Antagonistic aetinomycetes were isolated by starch casein agar medium and modified nutrient agar medium with 1%glucose used as a base for primary screening.Significant antimicrobial metabolite producing strains were selected and identified by using biochemical and 16S rDNA level.Minimum inhibitory concentrations of the organic extracts were done by using broth micro dilution method.Results:Among the 210 actinomyeetes,64.3%exhibited activity against Gram positive bacteria,48.5%showed activity towards Cram negative bacteria,38.8%exhibited both Cram positive and negative bacteria and 80.85%isolates revealed significant antifungal activity.However,five isolates AP-5,AP-18,AP-41 and AP-70 showed significant antimicrobial activity.The analysis of cell wall hydrolysates showed the presence of LL-diaminopimelic acid and glycine in all the isolates.Sequencing analysis indicated that the isolates shared 98.5%-99.8%sequence identity to the 16S rDNA gene sequences of the Streptomyces taxons.The antimicrobial substances were extracted using hexane and ethyl acetate from spent medium in which strains were cultivated at 30X for five days.The antimicrobial activity was assessed using broth micro dilution technique.Each of the culture extracts from these five strains showed a typical polyenelike property.The lowest minimum inhibitory concentrations of ethyl acetate extracts against Escherichia coli and Cumularia lunula were 67.5 and 125.0μg/mL,respectively.Conclusions:It can be concluded that hexane and ethyl acetate soluble extracellular products of novel isolates are effective against pathogenic bacteria and fungi. | Valan Arasu M Asha KRT Duraipandiyan V Ignacimuthu S Agastian P | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，10： | 5 |
| 2 | NAD-alcohol dehydrogenase and superoxide dismutase activity in Zea mays under hypoxic and posthypoxic stress regime显示文摘 | Pandey O P Asha K Hoque H | 2000 | Plant Biology2000，27，1： | 1 |
| 3 | Meso-tetrakis(p-sulfonatophenyl)N-confused porphyrin tetrasodium salt:a potential sensitizer for photodynamic therapy显示文摘 | THOMAS A P SANEESH BABU P S ASHA NAIR S | | 0，，11： | 1 |
| 4 | Production of cellulose-free endoxy- lanase from novel alkalophilic thermotolerant Bacillus pumilus by solid-state fermentation and its application in wastepaper recycling显示文摘 | ASHA P C PREMA P | 2007 | Bioresource Technology2007，98，3： | 1 |
| 5 | Cytotoxicity and genotoxicity of silver nanoparticles in human cells显示文摘 | Asha Rani P V Low K M G Valiyaveettil S | 2009 | ACS Nano2009，3，2： | 1 |
| 6 | Induction therapy in pediatric renal transplant recipients 显示文摘 | Asha M Dechu P | 2007 | Pediatric Drugs2007，9，5： | 1 |
| 7 | Effects of single and combined microalgae on larval growth,development and survival of the commercial sea cucumber holothuria spinifera theel显示文摘 | Asha P S Muthiah P | 2006 | Aquaculture Research2006，37，2： | 1 |
| 8 | TRAF6-dependent NF-KB transcriptional activity during mouse development显示文摘 | Kathleen M D Asha L B Barker P A | 2004 | Dev Dyn2004，231，1： | 1 |
| 9 | Multiple forms of al- pha-expansin genes are expressed during banana fruit ripening and development显示文摘 | ASHA SANE V A SANE A P NATH F | 2007 | Postharvest Biology and Technology2007，45，2： | 1 |
| 10 | Centrifuge modeling of moisture in silty soil显示文摘 | ASHA P SMITHA R N | 2000 | Journal of Geotechnical Engineering2000，126，8： | 1 |
| 11 | GLCM-basedchi-square histogram distance for automatic detectionof defects on patterned textures显示文摘 | Asha V Bhajantri N U Nagabhushan P | 2011 | International Journalof Computational Vision and Robotics2011，4，： | 1 |
| 12 | Purification and partial characterization of polygalacturonase from Streptomyces lydicus 显示文摘 | Jacoba N Asha Poornaa C Prema P | 2008 | Bioresour Yechno12008，99，14： | 1 |
| 13 | NRAGE, A Novel MAGE Protein, Interacts with the p75 Neurotrophin Receptor and Facilitates Nerve Growth Factor–Dependent Apoptosis显示文摘 | Amir H Salehi Philippe P Roux Chris J Kubu Christine Zeindler Asha Bhakar Laura-Lee Tannis Joseph M Verdi Philip A Barker | 2000 | Neuron2000，，2： | 1 |
| 14 | Production and partial characterization of endoxylanase by Bacillus pumilus using agro industrial residues显示文摘 | Asha Poorna C Prema P | 2006 | Biochemical Engineering Journal2006，32，： | 1 |
| 15 | Spawning and larval rearing of the sea cucumber Holothuria ( Theelothuria ) spinifera Theel 显示文摘 | ASHA P S MUTHIAH P | 2002 | SPC Beche-de-mer InfBull2002，16，9： | 1 |
| 16 | Mor- ganella morganii, subspecies Morganii, biogroup A: An unu- sual causative pathogen of brain abscess显示文摘 | Asha B P Shohha D N Lakshminarayana S A eta| | 2012 | J Neurosci Rural Pract2012，3，3： | 1 |
| 17 | Multiple forms of α-expansin genes are expressed during banana fruit ripening and development显示文摘 | Asha Sane V A Sane A P | 2007 | Postharvest Biology and Technology2007，45，2： | 1 |
| 18 | Effects of temperature, salinity and pH on lar-val growth, survival and development of the sea cucumberHolothuria spinifera Theel显示文摘 | PS Asha P Muthiah | 2005 | Aquaculture2005，250，34： | 1 |
| 19 | Effects of temperature,salinity and pH on larval growth,survival and development of the sea cucumber Holothuria spinifera Theel 显示文摘 | Asha F S amd Muthiah P | 2005 | Aquaculture2005，，250： | 1 |
| 20 | Effects of temperature,salinity and pH on larval growth,survival and development of the sea cucumber Holothuria spinifera Theel显示文摘 | ASHA P S MUTHIAH P | | 0，，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员