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| 1 | Precise measurement technique for the stable acoustic cavitation bubble显示文摘Based on the periodic oscillation of the stable acoustic cavitation bubble, we present a precise measure-ment technique for the bubble evolution. This technique comprises the lighting engineering of pulsing laser beam whose phase can be digitally shifted, and the long distance microphotographics. We used a laser, an acousto-optic modulator, a pulse generator, and a long distance microscope. The evolution of a levitated bubble can be directly shown by a series of bubble’s images at different phases. Numerical simulation in the framework of the Rayleigh-Plesset bubble dynamics well supported the experimental result, and the ambient radius of the bubble, an important parameter re-lated to the mass of the gas inside the bubble, was obtained at the same time. | HUANG Wei CHEN Weizhong LIU Yanan GAO Xianxian JIANG Li'an XU Junfeng ZHU Yifei | 2005 | Chinese Science Bulletin2005，50，21： | 8 |
| 2 | Whole genome sequencing of 10K patients with acute ischaemic stroke or transient ischaemic attack: design, methods and baseline patient characteristics显示文摘Background and purpose Stroke is the second leading cause of death worldwide and the leading cause of mortality and long-term disability in China,but its underlying risk genes and pathways are far from being comprehensively understood.We here describe the design and methods of whole genome sequencing(WGS)for 10914 patients with acute ischaemic stroke or transient ischaemic attack from the Third China National Stroke Registry(CNSR-III).Methods Baseline clinical characteristics of the included patients in this study were reported.DNA was extracted from white blood cells of participants.Libraries are constructed using qualified DNA,and WGS is conducted on BGISEQ-500 platform.The average depth is intended to be greater than 30×for each subject.Afterwards,Sentieon software is applied to process the sequencing data under the Genome Analysis Toolkit best practice guidance to call genotypes of single nucleotide variants(SNVs)and insertion-deletions.For each included subject,21 fingerprint SNVs are genotyped by MassARRAY assays to verify that DNA sample and sequencing data originate from the same individual.The copy number variations and structural variations are also called for each patient.All of the genetic variants are annotated and predicted by bioinformatics software or by reviewing public databases.Results The average age of the included 10914 patients was 62.2±11.3 years,and 31.4%patients were women.Most of the baseline clinical characteristics of the 10914 and the excluded patients were balanced.Conclusions The WGS data together with abundant clinical and imaging data of CNSR-III could provide opportunity to elucidate the molecular mechanisms and discover novel therapeutic targets for stroke. | Si Cheng Zhe Xu Yang Liu Jinxi Lin Yong Jiang Yilong Wang Xia Meng Anxin Wang Xinying Huang Zhimin Wang Guohua Chen Songdi Wu Zhengchang Jia Yongming Chen Xuerong Qiu Jun Wu Binbin Song Weizhong Ji Zhongping An Wenjun Xue Lili Zhao Yu Geng Hongyan Li Hao Li Yongjun Wang | 2021 | Stroke & Vascular Neurology2021，6，2： | 8 |
| 3 | Effects of adding sodium dichloroacetate to low-protein diets on nitrogen balance and amino acid metabolism in the portaldrained viscera and liver of pigs显示文摘Background:Identifying regulatory measures to promote glucose oxidative metabolism while simultaneously reducing amino acid oxidative metabolism is one of the foremost challenges in formulating low-protein(LP)diets designed to reduce the excretion of nitrogen-containing substances known to be potential pollutants.In this study,we investigated the effects of adding sodium dichloroacetate(DCA)to a LP diet on nitrogen balance and amino acid metabolism in the portal-drained viscera(PDV)and liver of pigs.To measure nitrogen balance,18 barrows(40±1.0 kg)were fed one of three diets(n=6 per group):18%crude protein(CP,control),13.5%CP(LP),and 13.5%CP+100 mg DCA/kg dry matter(LP-DCA).To measure amino acid metabolism in the PDV and liver,15 barrows(40±1.0 kg)were randomly assigned to one of the three diets(n=5 per group).Four essential amino acids(Lys,Met,Thr,and Trp)were added to the LP diets such that these had amino acid levels comparable to those of the control diet.Results:The LP-DCA diet reduced nitrogen excretion in pigs relative to that of pigs fed the control diet(P<0.05),without any negative effects on nitrogen retention(P>0.05).There were no differences between the control and LP-DCA groups with respect to amino acid supply to the liver and extra-hepatic tissues in pigs(P>0.05).The net release of ammonia into the portal vein and production rate of urea in the liver of pigs fed the LP-DCA diet was reduced relative to that of pigs fed the control and LP diets(P<0.05).Conclusion:The results indicated that addition of DCA to a LP diet can efficiently reduce nitrogen excretion in pigs and maximize the supply of amino acids to the liver and extra-hepatic tissues. | Weizhong Sun Yunxia Li Zhiru Tang Huiyuan Chen Ke Wan Rui An Liuting Wu Zhihong Sun | 2020 | Journal of Animal Science and Biotechnology2020，11，3： | 2 |
| 4 | EFFECT OF Na,K AND Ce ON CRACK PROPAGATION RESISTANCE FOR ALLOY 8090显示文摘The crack propagation resistance for alloy 8090 sheet decreases with the increase of content ofNa and K impurities.An improvement over the fracture toughness and crack initiation resist-ance for the alloy containing Na and K within certain limit may be made by adding 0.05%Ce.This beneficial modification would not be manifested if the alloy contained more Na andK.One of the reasons why Na and K injure the toughness of the alloy might be due to thatthey cause the precipitation of T1 phase along grain and subgrain boundaries and acceleratethe abnormal growth of recystallized grains. | MENG Liang ZHANG Baochang LIANG Ying ZHANG Weizhong TIAN Puke Northwestern Polytechnical University,Xi’an,China | 1992 | Acta Metallurgica Sinica(English Letters)1992，5，5： | 0 |
| 5 | Simulation and design of a heat-integrated double-effect reactive distillation process for propylene glycol methyl ether production显示文摘A double-effect reactive distillation(DERD)process was proposed for the production of propylene glycol methyl ether from propylene oxide and methanol to overcome the shortcoming of low selectivity and high-energy consumption in the tubular plug-flow reactor.A single-column reactive distillation(RD)process was conducted under optimized operating conditions based on sensitivity analysis as a reference.The results demonstrated that the proposed DERD process is able to achieve more than 95%selectivity of the desired product.After that,a design approach of the DERD process with an objective of the minimum operating cost was proposed to achieve further energy savings in the RD process.The proposed DERD configuration can provide a large energy-savings by totally utilization of the overhead vapor steam in the high-pressure RD column.A comparison of the single-column RD process revealed that the proposed DERD process can reduce the operating cost and the total annual cost of 25.3%and 30.7%,respectively,even though the total capital cost of DERD process is larger than that of the RD process. | Ran An Shengxin Chen Shun Hou Yuting Zhu Chunhu Li Xinbao Zhu Ruixia Liu Weizhong An | 2022 | Chinese Journal of Chemical Engineering2022，，12： | 0 |
| 6 | An Investigation of Bubble Motion in the Fluidic Oscillator显示文摘Enhanced gas-liquid mass transfer is significant for the desulfurization and denitration of ship exhaust gases.As a fluid device,the special structure of the fluidic oscillator generates self-excited oscillations that can effectively enhance the mass transfer process of gas-liquid.But there are few studies on the internal gas-liquid flow.The transportation of individual bubbles in the fluidic oscillator was investigated by a high-speed camera and digital image analysis.The results show that the bubble experienced a significant deceleration process in the chamber region of the fluidic oscillator.In addition,the maximum bubble offset increased with the diameter of the initial bubble.The trajectory of the bubble showed zigzag movement due to the deflecting oscillation of the fluidic oscillator.At the same time,the deformation of the bubble was intensified by the deflecting oscillation.The deformation ratio of the bubble increased with the increase of Reynolds number.By studying the transport process of a single bubble in the fluid oscillator,it is considered that the fluid oscillator has the potential to be a new bubble generator. | BIE Haiyan XUE Licheng LI Yulong LI Yunxia LIN Zixin AN Weizhong | 2023 | Journal of Ocean University of China2023，22，2： | 0 |
| 7 | Representation and Inhibition of Abnormal Arcing in Plasma Vapor Deposition Filming显示文摘Introduction During the filming process of plasma vapor deposition,arcing takes place in plasma cavity due to target pollution,charge accumulation and Insulating ability reduction.Frequent arcing ablates base material,reduces | Kong Linggang Jiang Qing'an Zhang Weizhong | 2007 | 兰州交通大学学报2007，26，6： | 0 |
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