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| 1 | Resection of early esophageal neoplasms: The pendulum swings from surgical to endoscopic management显示文摘Esophageal cancer is a highly lethal disease and is the sixth leading cause of cancer related mortality in the world.The standard treatment is esophagectomy which is associated with significant morbidity and mortality.This led to development of minimally invasive,organ sparing endoscopic therapies which have comparable outcomes to esophagectomy in early cancer.These include endoscopic mucosal resection and endoscopic submucosal dissection.In early squamous cell cancer,endoscopic submucosal dissection is preferred as it is associated with cause specific 5-year survival rates of 100%for M1 and M2 tumors and 85%for M3 and SM1 tumors and low recurrence rates.In early adenocarcinoma,endoscopic resection of visible abnormalities is followed by ablation of the remaining flat Barrett’s mucosa to prevent recurrences.Radiofrequency ablation is the most widely used ablation modality with others being cryotherapy and argon plasma coagulation.Focal endoscopic mucosal resection followed by radiofrequency ablation leads to eradication of neoplasia in 93.4%of patients and eradication of intestinal metaplasia in 73.1%of patients.Innovative techniques such as submucosal tunneling with endoscopic resection are developed for management of submucosal tumors of the esophagus.This review includes a discussion of various endoscopic techniques and their clinical outcomes in early squamous cell cancer,adenocarcinoma and submucosal tumors.An overview of comparison between esophagectomy and endoscopic therapy are also presented. | Vedha Sanghi Hina Amin Madhusudhan R Sanaka Prashanthi N Thota | 2019 | World Journal of Gastrointestinal Endoscopy2019，11，10： | 4 |
| 2 | Barrett's esophagus:Prevalence and risk factors in patients with chronic GERD in Upper Egypt显示文摘AIM:To determine the prevalence and possible risk factors of Barrett's esophagus(BE) in patients with chronic gastroesophageal reflux disease(GERD) in El Minya and Assuit, Upper Egypt.METHODS:One thousand consecutive patients with chronic GERD symptoms were included in the study over 2 years.They were subjected to history taking including a questionnaire for GERD symptoms, clinical examination and upper digestive tract endoscopy.Endoscopic signs suggestive of columnar-lined esophagus(CLE) were defined as mucosal tongues or an upward shift of the squamocolumnar junction.BE was diagnosed by pathological examination when specialized intestinal metaplasia was detected histologically in suspected CLE.pH was monitored in 40 patients.RESULTS:BE was present in 7.3% of patients with chronic GERD symptoms, with a mean age of 48.3 ± 8.2 years, which was signif icantly higher than patients with GERD without BE(37.4 ± 13.6 years).Adenocarcinomawas detected in eight cases(0.8%), six of them in BE patients.There was no signiflcant difference between patients with BE and GERD regarding sex, smoking, alcohol consumption or symptoms of GERD.Patients with BE had significantly longer esophageal acid exposure time in the supine position, measured by pH monitoring.CONCLUSION:The prevalence of BE in patients with GERD who were referred for endoscopy was 7.3%.BE seems to be associated with older age and more in patients with nocturnal gastroesophageal reflux. | Yasser M Fouad Madiha M Makhlouf Heba M Tawfik Hussein El Amin Wael Abdel Ghany Hisham R El-khayat | 2009 | World Journal of Gastroenterology2009，15，28： | 4 |
| 3 | PPARγ Activation Primes Human Monocytes into Alternative M2 Macrophages with Anti-inflammatory Properties显示文摘 | M. Amine Bouhlel Bruno Derudas Elena Rigamonti Rébecca Dièvart John Brozek Stéphan Haulon Christophe Zawadzki Brigitte Jude Gérard Torpier Nikolaus Marx Bart Staels Giulia Chinetti-Gbaguidi | 2007 | Cell Metabolism2007，，2： | 2 |
| 4 | Definition of Patients Presenting a High Risk of Developing Peritoneal Carcinomatosis After Curative Surgery for Colorectal Cancer: A Systematic Review显示文摘 | Charles Honoré Diane Goéré Amine Souadka Frédéric Dumont Dominique Elias | 2013 | Annals of Surgical Oncology2013，，1： | 2 |
| 5 | Rapid and sensitive microplate assay for screening the effect of silver and goldnanoparticles on bacteria显示文摘 | AMIN R M MOHAMED M B RAMADAN M A | 2009 | Nanomedicine2009，4，6： | 1 |
| 6 | Estimating parameters in continuous univariate distributions with a shifted origin显示文摘 | CHENG R C H AMIN N A K | 1983 | Journal of the Royal Statistical Society Series B (Methodological)1983，45，3： | 1 |
| 7 | Identification of mesenchymal progenitor calls in normal and osteoarthritic human articular cartilage显示文摘 | Alsalameh S Amin R Gemba T | 2004 | Arthritis Rheum2004，50，5： | 1 |
| 8 | Packing material and ripening methods affect mango fruit quality显示文摘 | ANWAR R MALIK A U AMIN M | 2008 | Int J Agri Biol2008，，10： | 1 |
| 9 | Inter- leukin-6 and type I interferon-regulated genes and chemokines mark disease activity in dermatomyositis 显示文摘 | BILGIC H YTFERBERG S R AMIN S | 2009 | Arthritis Rheum2009，6，11： | 1 |
| 10 | The pleiotorpic function of aspirin : me- chanisms of action 显示文摘 | AMIN A R ATYUR M G PILLINGER M | 1999 | Cell Mal Life Sci1999，56，34： | 1 |
| 11 | The development of microalbuminuria is associated with raised longitudinal adiponectin levels in female but not male adolescent patients with type 1 diabetes显示文摘 | Amin R Frystyk J Ong K | | 0，，： | 1 |
| 12 | No Significant Association of 14 Candidate Genes With Schizophrenia in a Large European Ancestry Sample: Implications for Psychiatric Genetics显示文摘 | Sanders Alan R Duan Jubao Levinson Douglas F Shi Jianxin He Deli Hou Cuiping Burrell Gregory J Rice John P Nertney Deborah A Olincy Ann Rozic Pablo Vinogradov Sophia Buccola Nancy G Mowry Bryan J Freedman Robert Amin Farooq Black Donald W | 2008 | The American Journal of Psychiatry2008，，4： | 1 |
| 13 | Additively manufactured porous tantalum implants显示文摘 | Wauthle R van der Stok J Amin YS | 2015 | Acta Biomater2015，14，3： | 1 |
| 14 | Effects of prepartum monensin feeding on energy metabolism and reproductive performance of postpartum high-producing Holstein dairy cows显示文摘 | Mahmood C M Abbas R G Amin T | 2012 | Pakistan Vet J2012，32，1： | 1 |
| 15 | Inclusion of the herpes simplex thymidine kinase gene in a replicating adenovirus does not augment antitumor efficacy显示文摘 | Lambright ES Amin K Wiewrodt R | 2001 | Gene Ther2001，8，： | 1 |
| 16 | Clavicular hook-plate: complications of retaining the implant 显示文摘 | Nadarajah R Mahaluxmivala J Amin A | 2005 | Injury2005，36，： | 1 |
| 17 | Identification of mesenchymal progenitor cells in normal and osteoarthritic human articular cartilage 显示文摘 | Alsalameh S Amin R Gemba T | 2004 | Arthritis Rheum2004，50，： | 1 |
| 18 | Clavicular hook-plate:complications of retaining the implant显示文摘 | Nadarajah R Mahaluxmivala J Amin A | 2005 | Injury2005，36，5： | 1 |
| 19 | A novel mechanism of action of tetracyclines:effects on nitric oxide synthases显示文摘 | Amin A R Attur M G Thakker G D | 1996 | Proc Natl Acad Sci USA1996，93，14： | 1 |
| 20 | Attention,learning,and arous- al of experimentally sleep-restricted adolescents in a simulated classroom显示文摘 | Beebe DW Rose D Amin R | 2010 | Journal of Adolescent Health2010，47，5： | 1 |
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