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13篇 您的检索式:作者名="AMEL L"
    题名 作者 年代 出处 被引量
1Diagnostic accuracy of FibroScan and comparison to liver fibrosis biomarkers in chronic viral hepatitis: A multicenter prospective study (the FIBROSTIC study)显示文摘Francoise Degos Paul Perez Bruno Roche Amel Mahmoudi Julien Asselineau Hélène Voitot Pierre Bedossa 2010Journal of Hepatology2010,,6:3
2Distal catheter obstruction from non-infectiouscause in ventriculo-peritoneal shunted children 显示文摘Amell K Olsen L 2004Eur J PediatrSurg2004,14,4:1
3Sonic Hedgehog Is Required for Progenitor Cell Maintenance in Telencephalic Stem Cell Niches显示文摘Robert Machold Shigemi Hayashi Michael Rutlin Mandar D Muzumdar Susana Nery Joshua G Corbin Amel Gritli-Linde Tammy Dellovade Jeffery A Porter Lee L Rubin Henryk Dudek Andrew P McMahon Gord Fishell 2003Neuron2003,,1:1
4Distal cather obstruction from non-in-fentions cause in ventriculoperitoneal shunted children 显示文摘Amell K Olsen L 2004Eur J Pediatr surg2004,14,4:1
5Histologic and prognostic study of nephroblastoma in central Tunisia 显示文摘AMEL L LEILA BF LAMIA K 2003Ann Urol (Paris)2003,37,4:1
6A TDG/CBP/RARα Ternary Complex Mediates the Retinoic Acid-dependent Expression of DNA Methylation-sensitive Genes显示文摘The thymine DNA glycosylase(TDG) is a multifunctional enzyme,which is essential for embryonic development.It mediates the base excision repair(BER) of G:T and G:U DNA mismatches arising from the deamination of 5-methyl cytosine(5-MeC) and cytosine,respectively.Recent studies have pointed at a role of TDG during the active demethylation of 5-MeC within CpG islands.TDG interacts with the histone acetylase CREB-binding protein(CBP) to activate CBP-dependent transcription.In addition,TDG also interacts with the retinoic acid receptor a(RARα),resulting in the activation of RARα target genes.Here we provide evidence for the existence of a functional ternary complex containing TDG,CBP and activated RARα.Using global transcriptome profiling,we uncover a coupling of de novo methylation-sensitive and RA-dependent transcription,which coincides with a significant subset of CBP target genes.The introduction of a point mutation in TDG,which neither affects overall protein structure nor BER activity,leads to a significant loss in ternary complex stability,resulting in the deregulation of RA targets involved in cellular networks associated with DNA replication,recombination and repair.We thus demonstrate for the first time a direct coupling of TDG's epigenomic and transcription regulatory function through ternary complexes with CBP and RARα.Hélène Léger Caroline Smet-Nocca Amel Attmane-Elakeb Sara Morley-Fletcher Arndt G.Benecke Sebastian Eilebrecht 2014Genomics, Proteomics & Bioinformatics2014,12,1:1
7Histoiogic and prognostic study of nephroblastoma in central Tunisia显示文摘 Leila BF Lamia K 2003Ann Urol(Paris)2003,37,4:1
8Determination of volatile or- ganic compounds in exhaled breath of patients with lung cancer u- sing solid phase microextraction and gas chromatography mass spec- trometry 显示文摘Magdalena L Tomasz L Amel B 2009Clin Chem Lab Med2009,47,5:1
9The global activator GacA of Pseudomonas aeruginosa PAO positively controls the production of the autoindueer N-butyryl-homoserine lactone and the formation of the virulence factors pyocyanin, cyanide and lipase 显示文摘Cornelia R Markus B Amel L 1997Molecular Microbiology1997,24,2:1
10Successful adaptation to climate change across scales 显示文摘Adger W N Amell N W Tompkins E L 2005Global Environmental Change2005,15,:1
11Tumor necrosis factor gene polymorphism association with increased susceptibility to non- Hodgkin's lymphomas显示文摘Besma B H J Amel C Adnene L 2006European Journal of Haematology2006,78,:1
12Distal catheter obstruction from non-infectious cause in ventriculo-peritoneal shunted children 显示文摘Amell K Olsen L 2004Eur J Pediatr Surg2004,14,4:1
13Temporary suppression of visual processing in an RSVP task : An attentional blink显示文摘RAYMOND J E SHAPIRO K L AMELL M 1992Journal of Ex- perimental Psychology: Human Perception andPerformance1992,18,:1
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