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| 1 | Is autoimmune hepatitis a frequent finding among HCV patients with intense interface hepatitis?显示文摘AIM:To evaluate the overlap of autoimmune hepatitis in hepatitis C virus(HCV)-infected patients with intense interface hepatitis.METHODS:Among 1759 patients with hepatitis C submitted to liver biopsy,92(5.2%) presented intense interface hepatitis.These patients were evaluated regarding the presence of antinuclear antibody(ANA),anti-smooth muscle antibody(SMA) and anti-liver/kidney microsomal antibody(LKM-1),levels of γ-globulin and histological findings related to autoimmune hepatitis(plasma cell infiltrate and presence of rosettes).RESULTS:Among patients with hepatitis C and intense interface hepatitis there was a low prevalence of autoantibodies(ANA=12%,SMA=5%,LKM-1=0%) and the median γ-globulin level was within the normal range.Typical histological findings of autoimmune disease were observed in only two cases(2%).After applying the score for diagnosis of autoimmune hepatitis,only one patient was classified with a definitive diagnosis of autoimmune hepatitis.Since overlap with autoimmune hepatitis was not the explanation for the intense necroinflammatory activity in patients with chronic hepatitis C we sought to identify the variables associated with this finding.The presence of intense interface hepatitis was associated with more advanced age,both at the time of infection and at the time of the biopsy,and higher prevalence of blood transfusion and alcohol abuse.CONCLUSION:Although possible,overlap with autoimmune hepatitis is a very rare association in HCV-infected patients with intense interface hepatitis,an unusual presentation which seems to be related to other host variables. | Rosilene G Badiani Vitória Becker Renata M Perez Carla AL Matos Lara B Lemos Valéria P Lanzoni Luis Eduardo C Andrade Alessandra Dellavance Antonio Eduardo B Silva Maria Lucia G Ferraz | 2010 | World Journal of Gastroenterology2010，16，29： | 7 |
| 2 | 中心和外周动脉脉搏波传导速度测量的重复性:社区动脉粥样硬化风险研究显示文摘通过脉搏波传导速度(pulsewavevelocity,PwV)检测动脉硬化程度是当前对高血压和心血管病风险评估和分层所日渐常用的方式。颈股动脉脉搏波传导速度(catroidfemoralarteryPWV,cfPWV)是一项公认的测定中心动脉硬化程度的方式。 | Meyer ML Tanaka H Palta P Patel MD Camplain R Couper D Cheng S Al Qunaibet A Poon AK Heiss G 陈云 叶鹏 | 2016 | 中华高血压杂志2016，24，5： | 6 |
| 3 | Resurgence of Fentanyl as a Drug of Abuse显示文摘Fentanyl,a powerful opioid analgesic introduced over 50 years ago,has a major role in modern anesthesia and chronic pain relief but has also gained a major role in illicit use.After a spike in fentanyl abuse between 2005 and 2007,fentanyl deaths decreased until 2010,with the introduction of“abuse‑deterrent”OxyContin.Our data indicate a recent rise in fentanyl‑related deaths beginning in 2013,which follows national trends.With the re‑emergence of the synthetic narcotic analgesic of high potency as a popular drug of abuse and the alarmingly increasing mortality associated with its abuse,there are profound implications for public health,health care providers,law enforcement,and the society in general. | Lauren P Tamburro Jenan H Al‑Hadidi Ljubisa Jovan Dragovic | 2016 | Journal of Forensic Science and Medicine2016，2，2： | 3 |
| 4 | Definition and diagnostic criteria of refractory ascites and hepatorenal syndrome in cirrhosis显示文摘 | V Arroyo P Gines AL Gerbes FJ Dudley P Gentilini G Laffi TB Reynolds H Ring-Larsen J Scholmerich | 1996 | Hepatology1996，，1： | 3 |
| 5 | Omentum facilitates liver regeneration显示文摘AIM:To investigate the mechanism of liver regeneration induced by fusing the omentum to a small traumatic injury created in the liver. We studied three groups of rats. In one group the rats were omentectomized; in another group the omentum was left in situ and was not activated,and in the third group the omentum was activated by polydextran particles. METHODS:We pre-activated the omentum by injecting polydextran particles and then made a small wedge wound in the rat liver to allow the omentum to fuse to the wound. We monitored the regeneration of the liver by determining the ratio of liver weight/body weight,by histological evaluation (including immune staining for cytokeratin-19,an oval cell marker),and by testing for developmental gene activation using reverse transcription polymerase chain reaction (RT-PCR). RESULTS:There was no liver regeneration in the omentectomized rats,nor was there significant regeneration when the omentum was not activated,even though in this instance the omentum had fusedwith the liver. In contrast,the liver in the rats with the activated omentum expanded to a size 50% greater than the original,and there was histologically an interlying tissue between the wounded liver and the activated omentum in which bile ducts,containing cytokeratin-19 positive oval cells,extended from the wound edge. In this interlying tissue,oval cells were abundant and appeared to proliferate to form new liver tissue. In rats pre-treated with drugs that inhibited hepatocyte growth,liver proliferation was ongoing,indicating that regeneration of the liver was the result of oval cell expansion. CONCLUSION:Activated omentum facilitates liver regeneration following injury by a mechanism that depends largely on oval cell proliferation. | Ashok K Singh Nishit Pancholi Jilpa Patel Natalia O Litbarg Krishnamurthy P Gudehithlu Perianna Sethupathi Mark Kraus George Dunea Jose AL Arruda | 2009 | World Journal of Gastroenterology2009，15，9： | 2 |
| 6 | Definition and diagnostic criteria of refractory ascites and hepatorenal syndrome in cirrhosis显示文摘 | V Arroyo P Gines AL Gerbes FJ Dudley P Gentilini G Laffi TB Reynolds H Ring-Larsen J Scholmerich | 1996 | Hepatology1996，，1： | 2 |
| 7 | 缺血性脑卒中的A—S-C—O(表型)分类显示文摘背景和目的:国际5国脑血管病专家提出一种新的脑卒中亚型分类法,旨在介绍完整的“脑卒中表型”分类的新观念,该分类是包括脑卒中的病因和存在的所有病因相关的疾病,并将病因疾病按严重程度分成3级。这与TOAST等缺血性脑卒中亚型分类不同,只应用脑卒中最可能的病因分类。 | Amarenco P Bogousslavsky J Caplan LR,et al 李新 王纪佐 | 2010 | 中华神经科杂志2010，43，6： | 2 |
| 8 | Measurement of the integrated luminosity of the Phase 2 data of the Belle Ⅱ experiment显示文摘From April to July 2018,a data sample at the peak energy of the T(4 S) resonance was collected with the Belle Ⅱ detector at the SuperKEKB electron-positron collider.This is the first data sample of the Belle Ⅱ experiment.Using Bhabha and digamma events,we measure the integrated luminosity of the data sample to be(496.3±0.3±3.0) pb-1,where the first uncertainty is statistical and the second is systematic.This work provides a basis for future luminosity measurements at Belle Ⅱ. | F.Abudinén I.Adachi P.Ahlburg H.Aihara N.Akopov A.Aloisio F.Ameli L.Andricek N.Anh Ky D.M.Asner H.Atmacan T.Aushev V.Aushev T.Aziz K.Azmi V.Babu S.Baehr S.Bahinipati A.M.Bakich P.Bambade Sw.Banerjee S.Bansal V.Bansal M.Barrett J.Baudot A.Beaulieu J.Becker P.K.Behera J.V.Bennett E.Bernieri F.U.Bernlochner M.Bertemes M.Bessner S.Bettarini V.Bhardwaj F.Bianchi T.Bilka S.Bilokin D.Biswas G.Bonvicini A.Bozek M.Bračko P.Branchini N.Braun T.E.Browder A.Budano S.Bussino M.Campajola L.Cao G.Casarosa C.Cecchi D.Červenkov M.-C.Chang P.Chang R.Cheaib V.Chekelian Y.Q.Chen Y.-T.Chen B.G.Cheon K.Chilikin H.-E.Cho K.Cho S.Cho S.-K.Choi S.Choudhury D.Cinabro L.Corona L.M.Cremaldi S.Cunliffe T.Czank F.Dattola E.De La Cruz-Burelo G.De Nardo M.De Nuccio G.De Pietro R.de Sangro M.Destefanis S.Dey A.De Yta-Hernandez F.Di Capua S.Di Carlo J.Dingfelder Z.Doležal I.Domínguez Jiménez T.V.Dong K.Dort S.Dubey S.Duell S.Eidelman M.Eliachevitch T.Ferber D.Ferlewicz G.Finocchiaro S.Fiore A.Fodor F.Forti A.Frey B.G.Fulsom M.Gabriel E.Ganiev M.Garcia-Hernandez R.Garg A.Garmash V.Gaur A.Gaz U.Gebauer A.Gellrich J.Gemmler T.Geßler R.Giordano A.Giri B.Gobbo R.Godang P.Goldenzweig B.Golob P.Gomis P.Grace W.Gradl E.Graziani D.Greenwald C.Hadjivasiliou S.Halder K.Hara T.Hara O.Hartbrich K.Hayasaka H.Hayashii C.Hearty M.T.Hedges I.Heredia de la Cruz M.Hernández Villanueva A.Hershenhorn T.Higuchi E.C.Hill H.Hirata M.Hoek S.Hollitt T.Hotta C.-L.Hsu Y.Hu K.Huang T.Iijima K.Inami G.Inguglia J.Irakkathil Jabbar A.Ishikawa R.Itoh M.Iwasaki Y.Iwasaki S.Iwata P.Jackson W.W.Jacobs D.E.Jaffe E.-J.Jang H.B.Jeon S.Jia Y.Jin C.Joo J.Kahn H.Kakuno A.B.Kaliyar G.Karyan Y.Kato T.Kawasaki H.Kichimi C.Kiesling B.H.Kim C.-H.Kim D.Y.Kim S.-H.Kim Y.K.Kim Y.Kim T.D.Kimmel K.Kinoshita C.Kleinwort B.Knysh P.Kodyš T.Koga I.Komarov T.Konno S.Korpar D.Kotchetkov N.Kovalchuk T.M.G.Kraetzschmar P.Križan R.Kroeger J.F.Krohn P.Krokovny W.Kuehn T.Kuhr M.Kumar R.Kumar K.Kumara S.Kurz A.Kuzmin Y.-J.Kwon S.Lacaprara Y.-T.Lai C.La Licata K.Lalwani L.Lanceri J.S.Lange K.Lautenbach I.-S.Lee S.C.Lee P.Leitl D.Levit P.M.Lewis C.Li L.K.Li S.X.Li Y.M.Li Y.B.Li J.Libby K.Lieret L.Li Gioi J.Lin Z.Liptak Q.Y.Liu D.Liventsev S.Longo A.Loos F.Luetticke T.Luo C.MacQueen Y.Maeda M.Maggiora S.Maity E.Manoni S.Marcello C.Marinas A.Martini M.Masuda K.Matsuoka D.Matvienko J.McNeil J.C.Mei F.Meier M.Merola F.Metzner M.Milesi C.Miller K.Miyabayashi H.Miyata R.Mizuk G.B.Mohanty H.Moon T.Morii H.-G.Moser F.Mueller F.J.Müller Th.Muller R.Mussa K.R.Nakamura E.Nakano M.Nakao H.Nakayama H.Nakazawa M.Nayak G.Nazaryan D.Neverov M.Niiyama N.K.Nisar S.Nishida K.Nishimura M.Nishimura M.H.A.Nouxman B.Oberhof S.Ogawa Y.Onishchuk H.Ono Y.Onuki P.Oskin H.Ozaki P.Pakhlov G.Pakhlova A.Paladino T.Pang E.Paoloni H.Park S.-H.Park B.Paschen A.Passeri S.Patra S.Paul T.K.Pedlar I.Peruzzi R.Peschke R.Pestotnik M.Piccolo L.E.Piilonen P.L.M.Podesta-Lerma V.Popov C.Praz E.Prencipe M.T.Prim M.V.Purohit P.Rados M.Remnev P.K.Resmi I.Ripp-Baudot M.Ritter M.Ritzert G.Rizzo L.B.Rizzuto S.H.Robertson D.Rodríguez Pérez J.M.Roney C.Rosenfeld A.Rostomyan N.Rout G.Russo D.Sahoo Y.Sakai D.A.Sanders S.Sandilya A.Sangal L.Santelj P.Sartori Y.Sato V.Savinov B.Scavino M.Schram H.Schreeck J.Schueler C.Schwanda A.J.Schwartz B.Schwenker R.M.Seddon Y.Seino A.Selce K.Senyo M.E.Sevior C.Sfienti C.P.Shen H.Shibuya J.-G.Shiu A.Sibidanov F.Simon S.Skambraks R.J.Sobie A.Soffer A.Sokolov E.Solovieva S.Spataro B.Spruck M.Starič S.Stefkova Z.S.Stottler R.Stroili J.Strube M.Sumihama T.Sumiyoshi D.J.Summers W.Sutcliffe M.Tabata M.Takizawa U.Tamponi S.Tanaka K.Tanida H.Tanigawa N.Taniguchi Y.Tao P.Taras F.Tenchini E.Torassa K.Trabelsi T.Tsuboyama N.Tsuzuki M.Uchida I.Ueda S.Uehara T.Uglov K.Unger Y.Unno S.Uno P.Urquijo Y.Ushiroda S.E.Vahsen R.van Tonder G.S.Varner K.E.Varvell A.Vinokurova L.Vitale A.Vossen E.Waheed H.M.Wakeling K.Wan W.Wan Abdullah B.Wang M.-Z.Wang X.L.Wang A.Warburton M.Watanabe S.Watanuki J.Webb S.Wehle N.Wermes C.Wessel J.Wiechczynski P.Wieduwilt H.Windel E.Won S.Yamada W.Yan S.B.Yang H.Ye J.Yelton J.H.Yin M.Yonenaga Y.M.Yook C.Z.Yuan Y.Yusa L.Zani J.Z.Zhang Z.Zhang V.Zhilich Q.D.Zhou X.Y.Zhou V.I.Zhukova V.Zhulanov A.Zupanc | 2020 | Chinese Physics C2020，44，2： | 2 |
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