|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Efficacy of 1.2L polyethylene glycol plus ascorbic acid for bowel preparations显示文摘BACKGROUND A low-volume polyethylene glycol(PEG) solution that combines ascorbic acid with PEG-based electrolyte solution(PEG-ASC) is gaining mainstream acceptance for bowel preparation due to reduced volume and improved taste.Although several reports showed that bowel preparation with PEG-ASC volume lower than 2.0 L with laxative agents could be an alternative to traditional preparation regimen, the cleansing protocols have not been fully investigated.AIM To evaluate the cleansing efficacy of 1.2 L PEG-ASC solution comparing with 2.0 L PEG electrolyte(PEG-ELS) for bowel preparations.METHODS A randomized, single-blinded, open-label, single-center, non-inferiority study was conducted. In total, 312 Japanese adult patients(aged > 18 years) who underwent colonoscopy were enrolled. Patients were randomly allocated to bowel lavage with either 1.2 L of PEG-ASC solution with at least 0.6 L of an additional clear fluid(1.2 L PEG-ASC group) or 2.0 L of PEG-ELS(PEG-ELS group). Then, 48 mg of sennoside was administered at bedtime on the day before colonoscopy, and the designated drug solution was administered at the hospital on the day of colonoscopy. Bowel cleansing was evaluated using the Boston Bowel Preparation Scale(BBPS). The volume of fluid intake and required time for bowel preparation were evaluated. Furthermore, compliance, patient tolerance,and overall acceptability were evaluated using a patient questionnaire, which was assessed using a visual analog scale.RESULTS In total, 291 patients(1.2 L PEG-ASC group, 148; PEG-ELS group, 143) completed the study. There was no significant difference in successful cleansing, defined as a BBPS score ≥ 2 in each segment, between the two groups(1.2 L PEG-ASC group, 91.9%; PEG-ELS group, 90.2%; 95%CI:-0.03-0.09). The required time for bowel preparation was significantly shorter(164.95 min ± 68.95 min vs 202.16 min± 68.69 min, P < 0.001) and the total fluid intake volume was significantly lower(2.23 L ± 0.55 L vs 2.47 L ± 0.56 L, P < 0.001) in the 1.2 L PEG-ASC group than in the PEG-ELS group. Palatability, acceptability of the volume of solution, and overall acceptability evaluated using a patient questionnaire, which was assessed by the visual analog scale, were significantly better in the 1.2 L PEG-ASC group than in the PEG-ELS group(7.70 cm ± 2.57 cm vs 5.80 cm ± 3.24 cm, P < 0.001). No severe adverse event was observed in each group.CONCLUSION The 1.2 L PEG-ASC solution was non-inferior to the 2.0 L PEG-ELS solution in terms of cleansing efficacy and had better acceptability among Japanese patients. | Hiroyuki Tamaki Teruyo Noda Masahiro Morita Akina Omura Atsushi Kubo Chikara Ogawa Toshihiro Matsunaka Mitsushige Shibatoge | 2019 | World Journal of Clinical Cases2019，7，4： | 4 |
| 2 | Modulation of the fecal bile acid profile by gut microbiota in cirrhosis显示文摘 | Genta Kakiyama William M. Pandak Patrick M. Gillevet Phillip B. Hylemon Douglas M. Heuman Kalyani Daita Hajime Takei Akina Muto Hiroshi Nittono Jason M. Ridlon Melanie B. White Nicole A. Noble Pamela Monteith Michael Fuchs Leroy R. Thacker Masoumeh Sikaro | 2013 | Journal of Hepatology2013，，5： | 3 |
| 3 | Postoperative shivering in children and causative factors显示文摘 | Akina Esmaoglu A Boyaci A | 2005 | Paediatr Anaesth2005，15，12： | 1 |
| 4 | J Anal Lett显示文摘 | KARYAKIN A A GITELMACHER O KARY- AKINA E E | 1994 | 27 (15) : 2861-28691994，27，15： | 1 |
| 5 | Toll-like receptor signaling显示文摘 | Akina S Takoda K | 2004 | Nat Rev Immunol2004，4，7： | 1 |
| 6 | Monitoring and control of biological nutrient removal in a sequencing batch reactor 显示文摘 | AkIna B S Ugurlu A | 2005 | Process Biochemistry2005，40，8： | 1 |
| 7 | Oxidation of phenols and hydrazones with tert-butyl hydroperoxide and catalysis by Co (salen) 显示文摘 | AKINA YANNAZAKI | 1985 | Nippon Kagaku Kai shi1985，，3： | 1 |
| 8 | Dexmedetomidine added to levbupivacaine prolongs axillary brachial plexus block显示文摘 | EsmaogluA YegenogluF AkinA | 2010 | Anesth Analg2010，111，6： | 1 |
| 9 | Brachial-ankle pulse wave velocity as a marker of arteriosclerotic vascular damage and cardiovascular risk 显示文摘 | Akina Y Hirofum T Tomio A | 2003 | Hypertens Res2003，26，： | 1 |
| 10 | Dexmedetomidine vs midazolam for premedication of pediatric patientsundergoing anesthesia显示文摘 | AkinA BayramA EsmaogluA | 2012 | Paediatr Anaesth2012，22，9： | 1 |
| 11 | Rapid and cost-effective SNP detection method: application of SmartAmp2 to pharmacogenomics research显示文摘 | Yasumasa Mitani Alexander Lezhava Aki Sakurai Akina Horikawa Makoto Nagakura Yoshihide Hayashizaki Toshihisa Ishikawa | 2009 | Pharmacogenomics2009，，： | 1 |
| 12 | Endthelium-dependent flow-mediated vasodilation in coronary and brachial arteries in suspected coronary artery disease显示文摘 | Takase B Vehata A Akina T | 1998 | Am J Cardiol1998，82，10： | 1 |
| 13 | Dexmedetemidiand, meperdine prevent postanaesthetic shivering 显示文摘 | Biter A Esmaoglu A AkinA | 2006 | Euro J Annesth2006，23，2： | 1 |
| 14 | Dexmedetomidine and mep- eridine prevent post anesthetic shivering 显示文摘 | Bicer C ESMAOGLU A Akina | 2006 | European Journal of Anaesthesiol2006，23，2： | 1 |
| 15 | Social model of depression in mice of C57 BL/6J strain 显示文摘 | Kudryavtseva NN Bakshtanovskaya IV Kory- akina LA | 1991 | Pharmacol Biochem Behav1991，38，2： | 1 |
| 16 | 如何克服恐水心理显示文摘Q1:有一个问题想问下编辑们:夏天快到了,想带孩子游泳顺便教教他,却发现常去的游泳馆水太深,估计有2米多,脚站不到池底,更别提教孩子了。请问这种隋况下有什么办法能让孩子学会游泳呢? | Akina | 2012 | 游泳2012，，4： | 1 |
| 17 | Forsus Nitinol Flat Spring and Jasper Jumper corrections of Class Ⅱ division 1 malocclusions显示文摘 | Karacaya S Akina E Olmez H | 2006 | Angle Orthod2006，76，4： | 1 |
| 18 | Differences in organochlorine accumulation accompanying life history in the catadromous eel Anguilla japonica and the marine eel Conger myriaster显示文摘 | Takaomi Arai Akina Takeda | 2012 | Ecotoxicology2012，，4： | 1 |
| 19 | 关于蝶泳的陆上练习等显示文摘编辑您好!我女儿今年13岁,身高162公分,体重45公斤。她在每天放学后练习游泳已有6年,目前,她的成绩是100米蝶泳1分14秒,50米蝶泳成绩是32秒。她想在1~2年内冲击一级运动员(100米蝶泳1分8秒,50米蝶泳30.5秒)。 | 姜义环 Akina 杨听宇 | 2013 | 游泳2013，，3： | 0 |
| 20 | 如何克服恐水心理显示文摘Q1:初学游泳的时候(当然现在也不是完全没有问题),蛙、自、蝶三种姿势总有换气不充分的问题。当时总是担心头出水的时候呛到水,所以总是留半口气,也就是吐气不干净,导致很快缺氧。虽然知道在出水前一定要用力吐净,但就是不敢。比如,自由泳换气的时候要用力出“啪”的声音,做的时候其实是假的,声音大,胸腔里还是有气。仰泳好一些,因为头(嘴)一直在水面上。 | Akina | 2012 | 游泳2012，，3： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员