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| 1 | Further support for a Cretaceous age for the feathered-dinosaur beds of Liaoning,China:New ^(40)Ar/^(39)Ar dating of the Yixian and Tuchengzi Formations显示文摘We report new 40Ar/39Ar dating results ob-tained from total fusion and incremental-heating analyses of sanidine and biotite from three tuffs found interbedded within the fossil-bearing deposits of Liaoning, northeast China. The first is a new sample of the Bed 6 Sihetun tuff from the Yixian Formation, previously dated by our team as middle Early Cretaceous, and recently considered by Lo et al., partially reset due to metamorphism from a nearby ba-saltic sill. The second is the Yixian Bed 9 tuff from Heng-daozi considered by Lo et al. to be unaffected by metamor-phism and whose age, based on total fusion 40Ar/39Ar dating of biotite, argues for a Jurassic age for the Yixian Formation. The third tuff is a previously undated tuff from the upper part of the underlying Tuchengzi Formation. Single crystal total fusion 40Ar/39Ar analyses of the Sihetun sanidine showed homogeneous radiogenic Ar, Ca/K ratios, excellent reproducibility and gave a mean age of 125.0 ± 0.18 (1SD) ± 0.04 (SE) Ma. Single sanidine | C. C. Swisher III, WANG Xiaolin, ZHOU Zhonghe, WANG Yuanqing, JIN Fan, ZHANG Jiangyong , XU Xing, ZHANG Fucheng & WANG YuanDepartment of Geological Sciences, Wright Labs, Rutgers University, Piscataway, New Jersey 08854, USA (e-mail: cswish@rutgers. rci.e | 2002 | Chinese Science Bulletin2002，47，2： | 83 |
| 2 | Progress in carbon dioxide separation and capture: A review显示文摘这篇文章考察在 CO2 分离和俘获研究和工程取得的进步。各种各样的技术例如吸收,吸附,和膜分离,彻底地被讨论。象化学循环的燃烧和基于水合物的分离那样的新概念也简短被介绍。未来方向被建议。隐遁方法海洋授精和矿物质碳酸饱和技术例如造林,也被盖住。地下的注射和直接海洋垃圾场没被盖住。 | Hongqun Yang Zhenghe Xu Maohong Fan Rajender Gupta Rachid B Slimane Alan E Bland Ian Wright | 2008 | Journal of Environmental Sciences2008，20，1： | 89 |
| 3 | Surgical management of polycystic liver disease显示文摘Adult polycystic liver disease (PCLD) is an autosomal dominant condition commonly associated with autosomal dominant polycystic kidney disease (ADPKD). However in the last decade, it has been recognized that there is a distinct form of autosomal dominant PCLD that arises without concomitant ADPKD. Early knowledge of the pathogenesis was gained from the study of hepatic cysts in patients with ADPKD. Bile duct overgrowth after embryogenesis results in cystic hepatic dilatations that are known as biliary microhamartomas or von Meyenburg complexes. Further dilatation arises from cellular proliferation and fluid secretion into these cysts. There is a variable, broad spectrum of manifestations of PCLD. Although PCLD is most often asymptomatic, massive hepatomegaly can lead to disabling symptoms of abdominal pain, early satiety, persistent nausea, dyspnea, ascites, biliary obstruction, and lower body edema. Complications of PCLD include cyst rupture and cyst infection. Also, there are associated medical problems, especially intracranial aneurysms and valvular heart disease, which clinicians need to be aware of and evaluate in patients with PCLD. In asymptomatic patients, no treatment is indicated for PCLD. In the symptomatic patient, surgical therapy is the mainstay of treatment tailored to the extent of disease for each patient. Management options include cyst aspiration and sclerosis, open or laparoscopic fenestration, liver resection with fenestration, and liver transplantation. The surgical literature discussing treatment of PCLD, including techniques, outcomes, and complication rates, are summarized in this review. | Robert T Russell C Wright Pinson | 2007 | World Journal of Gastroenterology2007，13，38： | 20 |
| 4 | 子宫颈癌筛查异常妇女处理的共识指南(2006版)显示文摘2001年,美国阴道镜与宫颈病理学会(American Society for Colposcopyand Cervical Pathology,ASCCP)联合其他专业学会以及联邦与国际组织.制订了2001版的宫颈癌细胞学筛查结果异常妇女处理的共识指南。这是全面的、以循证医学为依据的指南,其目的是帮助所有亚专业的临床医生,处理每年约480万诊断为细胞学异常的美国妇女。 | 李志刚(翻译) Thomas C. Wright Jr L Stewart Massad Charles J. Dunton MarkSpitzer Edward J. Wilkinson DianeSolomon | 2008 | 循证医学2008，8，4： | 16 |
| 5 | 人类血压测量方法:美国心脏协会科学声明显示文摘准确的血压测量对高血压诊断与治疗至关重要。该文是美国心脏协会关于人类血压测量的最新科学声明。业已证实,在诊室许多电子血压计可以准确测量血压,同时减少与听诊法有关的人为误差。即使没有一个观察者在场,全自动电子血压计也可以通过多次测量提供较听诊法更准确的血压测量值。研究表明诊室外所测血压与诊室血压比较存在实质性差别。目前认为动态血压监测是诊室外血压评估的参考标准,当动态血压监测不可行或患者不能耐受时,家庭血压监测则是一个替代方法。 | 赵狄(摘译) 练桂丽(审校) Muntner P Shimbo D Carey RM Charleston JB Gaillard T Misra S Myers MG Ogedegbe G Schwartz JE Townsend RR Urbina EM Viera AJ White WB Wright JT Jr | 2019 | 中华高血压杂志2019，27，6： | 16 |
| 6 | 指南针:指向社会主义的替代性选择显示文摘对社会主义概念的讨论,如果不是置之于与资本主义的二元对立,而是将其与资本主义和国家主义同时进行比较,那我们可以把它定义为生产资料归整个社会共同所有,因此出于各种社会目的而进行的资源分配和使用须通过社会权力的实施才能实现的经济结构。社会权力不同于国家权力,也不同于经济权力,它是植根于公民社会中动员人们参与各种合作性、志愿性的集体活动的力量。本文从理论上考察了包括社会经济在内的五种最主要的通过社会权力有效控制经济生产与分配的途径。而其中的许多方案在世界各地的实践以及各种新的社会赋权形式的不断涌现表明,我们在资本主义内部实行的各种局部的、片段的社会赋权,也许最终会帮助我们超越资本主义的命运。 | 埃里克·欧林·赖特(Erik Olin Wright) 闻翔(译) | 2012 | 开放时代2012，，6： | 15 |
| 7 | Association of symptoms with gastrointestinal microbiota in irritable bowel syndrome显示文摘AIM:To investigate the correlations between selfreported symptoms of irritable bowel syndrome(IBS) and the gastrointestinal(GI) microbiota composition.METHODS:Fecal samples were collected from a total of 44 subjects diagnosed with IBS.Their symptoms were monitored with a validated inflammatory bowel disease questionnaire adjusted for IBS patients.Thirteen quantitative real-time polymerase chain reaction assays were applied to evaluate the GI microbiota composition.Eubacteria and GI bacterial genera(Bifidobacterium,Lactobacillus and Veillonella),groups(Clostridium coccoides/Eubacterium rectale,Desulfovibrio desulfuricans) and distinct bacterial phylotypes [closest 16S rDNA sequence resemblance to species Bifidobacterium catenulatum,Clostridium cocleatum,Collinsella aerofaciens(C.aerofaciens),Coprococcus eutactus(C.eutactus),Ruminococcus torques and Streptococcus bovis ] with a suspected association with IBS were quantified.Correlations between quantities or presence/absence data of selected bacterial groups or phylotypes and various IBSrelated symptoms were investigated.RESULTS:Associations were observed between subjects' self-reported symptoms and the presence or quantities of certain GI bacteria.A Ruminococcus torques(R.torques)-like(94% similarity in 16S rRNA gene sequence) phylotype was associated with severity of bowel symptoms.Furthermore,among IBS subjects with R.torques 94% detected,the amounts of C.cocleatum 88%,C.aerofaciens-like and C.eutactus 97% phylotypes were significantly reduced.Interesting observations were also made concerning the effect of a subject's weight on GI microbiota with regard to C.aerofaciens like phylotype,Bifidobacterium spp.and Lactobacillus spp.CONCLUSION:Bacteria seemingly affecting the symptom scores are unlikely to be the underlying cause or cure of IBS,but they may serve as biomarkers of the condition. | Erja Malinen Lotta Krogius-Kurikka Janne Nikkil Airi Palva Anna Lyra Anne Jskelinen Teemu Rinttil Terttu Vilpponen-Salmela Atte Johannes von Wright | 2010 | World Journal of Gastroenterology2010，16，36： | 13 |
| 8 | Antibiotic prophylaxis in variceal hemorrhage:Timing,effectiveness and Clostridium difficile rates显示文摘AIM:To investigate if antibiotics administered within 8 h of endoscopy reduce mortality or increase the incidence of Clostridium difficile infection(CDI).METHODS:A 2-year retrospective analysis of all patients who presented with first variceal hemorrhage was undertaken.The primary outcome measure was 28-d mortality.Secondary outcome measures were 28-d rebleeding rates and 28-d incidence of CDI.All patients were admitted to a tertiary liver unit with a consultantled,24-h endoscopy service.Patients received standard care including terlipressin therapy.Data collection included:primary and secondary outcome measures,timing of first administration of intravenous antibiotics,eti-ology of liver disease,demographics,endoscopy details and complications.A prospective study was undertaken to determine the incidence of CDI in the study population and general medical inpatients admitted for antibiotic therapy of at least 5 d duration.Statistical analysis was undertaken using univariate,non-parametric tests and multivariate logistic regression analysis.RESULTS:There were 70 first presentations of variceal hemorrhage during the study period.Seventy percent of cases were male and 65.7% were due to chronic alcoholic liver disease.In total,64/70(91.4%) patients received antibiotics as prophylaxis during their admission.Specifically,53/70(75.7%) received antibiotics either before endoscopy or within 8 h of endoscopy [peri-endoscopy(8 h) group],whereas 17/70(24.3%) received antibiotics at > 8 h after endoscopy or not at all(non peri-endoscopy group).Overall mortality and rebleeding rates were 13/70(18.6%) and 14/70(20%),respectively.The periendoscopy(8 h) group was significantly less likely to die compared with the non peri-endoscopy group [13.2% vs 35.3%,P = 0.04,odds ratio(OR) = 0.28(0.078-0.997)] and showed a trend towards reduced rebleeding [17.0% vs 29.4%,P = 0.27,OR = 0.49(0.14-1.74)].On univariate analysis,the non peri-endoscopy group [P = 0.02,OR = 3.58(1.00-12.81)],higher model for end-stage liver disease(MELD) score(P = 0.02),presence of hepatorenal syndrome [P < 0.01,OR = 11.25(2.24-56.42)] and suffering a clinical episode of sepsis [P = 0.03,OR = 4.03(1.11-14.58)] were significant predictors of death at 28 d.On multivariate logistic regression analysis,lower MELD score [P = 0.01,OR = 1.16(1.04-1.28)] and periendoscopy(8 h) group [P = 0.01,OR = 0.15(0.03-0.68)] were independent predictors of survival at 28 d.The CDI incidence(5.7%) was comparable to that in the general medical population(5%).CONCLUSION:Antibiotics administered up to 8 h following endoscopy were associated with improved survival at 28 d.CDI incidence was comparable to that in other patient groups. | Matthew RL Brown Graeme Jones Kathryn L Nash Mark Wright Indra Neil Guha | 2010 | World Journal of Gastroenterology2010，16，42： | 13 |
| 9 | 前交叉韧带重建术后感染的相关因素显示文摘前交叉韧带(anterior cruciate ligament,ACL)重建术后感染相对少见,但一旦发生,情况非常严重,潜在威胁大。近期研究表明,移植物选择可能是ACL重建术后感染的危险因素之一,吸烟、肥胖、糖尿病等亦与骨科等外科手术术后感染密切相关。本研究的目的在于探究ACL重建术后感染与患者年龄、体质量指数(body mass index,BMI)、吸烟、糖尿病、移植物选择等潜在危险因素的相关性。 | Brophy RH Wright RW Huston LJ 胡玮 | 2015 | 中国骨科临床与基础研究杂志2015，7，4： | 10 |
| 10 | 含某些碱金属盐的互穿聚合物网络的离子导电性显示文摘研究了由分子量为400的聚环氧乙烷(PEO400)、碱金属盐(NaI、LiClO_4或LiBF_4)与环氧树脂或不饱和聚酯树脂形成的互穿聚合物网络(IPN)的离子电导率与温度的关系,发现其1olσ-1/T符合Afrhenius公式,但在333K处直线斜率出现转折。这一现象可能与其中的PEO400-碱金属盐络合物具有某种有序结构有关。环氧树脂IPN的室温电导率达3×10^(-5)Scm^(-1),不饱和聚酯树脂IPN的室温电导率较低,(σ_(RT)=2×10^(-6)Scm^(-1)。然而,若在后者的聚酯大分子链中引入PEO400链段,增加它们与PEO400/LiClO_4络合物的相容性,则室温电导率与环氧树脂IPN相同,σ_(RT)=3×10^(-5)Scm^(-1)。 | 胡春圃 Wright P.V. | 1990 | 高分子材料科学与工程1990，6，3： | 10 |
| 11 | Combined analysis of land cover change and NDVI trends in the Northern Eurasian grain belt显示文摘我们在场在联合 MODIS 的时间系列分析的北欧亚的谷物带的地区性的环境监视的一条途径使差别植被索引(NDVI ) 正常化在时期 2001-2008 和陆地盖子变化(LCC ) 上的数据 2001 和 2008 MODIS 全球陆地盖子的分析产品(MCD12Q1 ) 。NDVI 趋势越过谷物带与是压倒性地否定的统计上重要(p0.05 ) 仅仅盖住 1% 土地的积极趋势出现。LCC 被在三个班之间的转变统治;农田,草地,和混合农田 / 天赋植被马赛克。联合我们 NDVI 趋势和 LCC 的分析,我们在与一致与的谷物带的南部的范围发现了农业放弃(到草地的农田) 的一个模式统计上重要(p0.05 ) 否定 NDVI 趋势并且多半由地区性的干旱开车。在谷物带的北范围,我们向农业增强发现了一个相反的趋势;在这种情况中,从农田马赛克由 LCC 代表了到纯农田,并且也与联系了统计上重要(p0.05 ) 否定 NDVI 趋势。相对小的簇统计上重要(p0.05 ) 与放弃和局部性的农业增强显示出的两块局部性的陆地相应的积极 NDVI 趋势那项陆地使用决策不是越过这个区域的制服。在北欧亚的谷物带的陆地表面变化在社会主义陆地任期和农业市场的苏联后面的重组的东方欧洲,俄国,和以前的领土是陆地盖子陆地使用变化(LCLUC ) 的一个更大的模式的部分。这里,我们证明 LCC 和 NDVI 趋势的联合分析在北欧亚的谷物带提供 LCLUC 的复杂性的一幅更完全的图画,包含更宽广的气候的强迫,和更狭窄的人为的影响,与力量独自从任何一个分析被获得比[出版摘要] | Christopher K. WRIGHT Kirsten M. de BEURS Geoffrey M. HENEBRY | 2012 | Frontiers of Earth Science2012，6，2： | 8 |
| 12 | 钠-葡萄糖共转运蛋白-2抑制剂或胰高血糖素样肽-1受体激动剂治疗成人2型糖尿病:临床实践指南显示文摘临床问题对于存在不同心血管风险及肾脏结局的2型糖尿病患者,在原有生活方式干预和/或其他降糖药物的基础上加用钠-葡萄糖共转运蛋白2(SGLT-2)抑制剂和胰高血糖素样肽1(GLP-1)受体激动剂的获益及风险是什么?现行做法几十年来,2型糖尿病的治疗决策都以控制血糖为主导。SGLT-2抑制剂和GLP-1受体激动剂在传统观念中常被用于二甲双胍治疗后血糖仍控制不佳的患者。目前这一现状已经发生了改变,这得益于多项临床研究结果。研究显示SGLT-2抑制剂和GLP-1受体激动剂拥有独立于药物降糖作用之外的对于动脉粥样硬化性心血管病(CVD)和慢性肾脏病(CKD)的获益。建议本指南阐述了针对不同风险分层的成人2型糖尿病患者使用SGLT-2抑制剂或GLP-1受体激动剂的建议。•伴有3种或更少的心血管风险因素且不存在CVD或CKD:不建议启动SGLT-2抑制剂或GLP-1受体激动剂治疗。(推荐等级:弱)•伴有3种以上心血管风险因素且不存在CVD或CKD:建议启动SGLT-2抑制剂治疗,不建议启动GLP-1受体激动剂治疗。(推荐等级:弱)•已经存在CVD或CKD:建议启动SGLT-2抑制剂治疗和GLP-1受体激动剂治疗。(推荐等级:弱)•已经存在CVD和CKD:建议启动SGLT-2抑制剂治疗(推荐等级:强)和GLP-1受体激动剂治疗。(推荐等级:弱)•对于那些想要进一步降低CVD和CKD结局风险的患者:推荐优先启用SGLT-2抑制剂治疗而非GLP-1受体激动剂治疗。(推荐等级:弱)这项指南是如何制订的一个由患者、临床医生和方法学家共同组成的国际小组提出了这些推荐意见。这些推荐意见基于可信度较高的指南的标准,并使用GRADE分级方法进行评估。该小组采用了息者个体化的观点。证据一项关于获益与风险的系统综述和网络meta分析(764项随机对照研究,包括421346例参与者)发现SGLT-2抑制剂和GLP-1受体激动剂可以降低总体死亡率、心肌梗死发生率、终末期肾病或肾衰竭的发生率(中等至高等质量的证据)。在不同的亚组中这些药物对卒中、因心力衰竭所致住院和其他主要不良事件有不同的影响。药物绝对获益的程度因患者个体风险的不同有很大的差异。(例如,对于接受了超过5年药物治疗的1000例患者,在最低风险人群中死亡人数减少了5人,在最高风险人群中死亡人数减少了48人)。一项关于预后的综述确认了14种风险预测模型,其中一种(RECODe)在证据总结中报告了大部分基线风险评估数据,小组利用该模型以支持风险分层的建议。考虑到患者的价值观及个体差异,指南推荐的支撑证据包括一项对已发表论文的系统综述、一项患者焦点小组研究、一项临床问题总结,以及一项指南调查。指南解读我们依据不同的CVD和CKD风险水平,综合考虑获益、风险和其他因素的平衡,以及每一个风险组别的实际问题,来对推荐意见进行分层。本指南强烈建议CVD和CKD患者使用SGLT-2抑制剂治疗,这说明专家组认为其具有显著的获益。而对于其他成人2型糖尿病患者,推荐等级较弱,这说明专家组想要在获益、风险及治疗花费上取得一个更好的平衡。临床医生通过该指南可以使用可靠的风险计算模型,如RECODe,来明确其患者的个体心血管和肾脏疾病风险。医患交互式总结临床证据和制订决策有助于患者知晓治疗选择,包括进行共同决策。2型糖尿病人群(全球患病率不断增长1-2)正面临着不断增加的心血管疾病、肾脏病和其他并发症的风险3。数十年来,2型糖尿病的管理始终以控制血糖及糖化血红蛋白(HbA1c)为治疗目标4-5,但是,最近的高质量随机对照研究已经对这种以血糖为中心的治疗模式发起了挑战。研究结果显示,强化血糖控制未必会降低大血管不良事件,它还可能带来不利影响监管机构现在要求新型糖尿病药物必须证明其具有心血管和肾脏获益才能获得批准。对两类新药--钠-葡萄糖共转运蛋白2(SGLT-2)抑制剂和胰高血糖素样肽1(GLP-1)受体激动剂(见框图1)的临床试验结果显示,在现有治疗方案(常规治疗)之上加用这些药物,对死亡、心肌梗死、卒中、心力衰竭和肾脏的结局(如进展为终末期肾病)都有获益8-12。 | Sheyu Li Per Olav Vandvik Lyubov Lytvyn Gordon H Guyatt Suetonia C Palmer Rene Rodriguez-Gutierrez Farid Foroutan Thomas Agoritsas Reed A C Siemieniuk Michael Walsh Lawrie Frere David J Tunnicliffe Evi V Nagler Veena Manja Bjφrn Olav Asvold Vivekanand Jha Mieke Vermandere Karim Gariani Qian Zhao Yan Ren Emma Jane Cartwright Patrick Gee Alan Wickes Linda Fems Robin Wright Ling Li Qiukui Hao Reem A Mustafa 无 郭鹤鸣(译) | 2021 | 英国医学杂志中文版2021，24，9： | 7 |
| 13 | 基于RBF神经网络的人体运动跟踪与姿态预测(英文)显示文摘本文采用径向基函数神经网络进行人体运动跟踪与人体姿态预测,利用采集的运动数据对本文提出的运动跟踪与姿态预测方法进行性能评估,给出部分测试和比较实验结果,实验结果表明,基于径向基函数神经网络的人体运动跟踪与人体姿态预测方法是可行的。 | 孙光民 陈德明 秦圣峰 Wright D.K. 康金胜 赵越 | 2007 | 仪器仪表学报2007，28，1： | 7 |
| 14 | A review of in-situ EBSD experiments显示文摘Automated EBSD or Orientation Imaging Microscopy (OIM) systems are being used in combination with other equipment within the scanning electron microscope (SEM) to perform in-situ measurements. This paper briefly reviews OIM studies of in-situ experiments performed using tensile and heating stages as well as in-situ serial sectioning. In particular, in-situ OIM scan results on an aluminum alloy sample deformed in tension; phase transformations in a cobalt sample, recrystallization and grain growth in a copper sample and serial sectioning of a nickel super-alloy sample are reviewed. | Stuart I. WRIGHT Matthew M. NOWELL | 2005 | 中国体视学与图像分析2005，10，4： | 6 |
| 15 | 向中国介绍电视胸腔镜肺叶切除术及如何避免西方的失误(英文)显示文摘目的在过去10~15年里,香港、日本和西方的临床医生开展了非小细胞肺癌的电视胸腔镜肺叶切除手术。虽然此种技术的支持者发表了结果满意的文章,但毫无疑问有些病人遭受了由于医生的技术尚处于学习曲线阶段或由于病例选择不当造成的失误。杂志投稿零星的报道和在国际会议上的个人交流并未被广泛传播,而且外科医生不太可能发表效果不好的结果,这些都导致报道的阳性误差。尽管我们中心已经有650例胸腔镜手术的经验,其中还包括食管切除、扩大胸腺切除、膈肌修补等复杂手术,但我们对开展非小细胞肺癌胸腔镜肺叶切除术仍很谨慎,因为我们不希望危及开胸手术的良好效果。另外,为了向中国医生全面系统地介绍这一经过慎重考虑的技术,对于将要开展胸腔镜肺叶切除术的医院,我们推荐了一个10步方案。本文还将介绍我们中心开展胸腔镜肺叶切除的经历,在过去12个月中技术的提高呈指数级增长,学习曲线达到平台期。本文详细介绍电视胸腔镜肺叶切除术,40例手术无死亡,5年生存率86%。根据现有的证据,在中国目前正在继续进行医疗改革之际,对合适的非小细胞肺癌进行胸腔镜手术应会使广大的人群获益。 | Gavin Michael Wright 刘伦旭 | 2006 | 中国微创外科杂志2006，6，9： | 6 |
| 16 | Self-management approaches for people with chronic conditions: a review显示文摘 | Julie Barlow Chris Wright Janice Sheasby Andy Turner Jenny Hainsworth | 2002 | Patient Education and Counseling2002，，2： | 6 |
| 17 | 基于随机暴雨移置方法的城市设计暴雨分析显示文摘城市地区暴雨洪灾发生频繁,合理计算设计暴雨是解决城市洪涝的重要前提。采用随机暴雨移置方法(Stochastic Storm Transposition,SST),设定暴雨移置区并提取出暴雨目录,通过区域性概率重采样与暴雨空间变换相结合的方式进行降雨频率分析,估计本地化的极端暴雨频率。以上海地区为例,研究发现暴雨移置区内暴雨分布具有空间异质性,暴雨随机移置概率不均,计算得到的设计暴雨方案包含了降雨时空分布信息,在不同重现期下设计暴雨的时空结构存在变异性,说明传统方法中采用的简化雨型和均一化空间分布假设会增加设计暴雨的不确定性。 | 周正正 刘曙光 Daniel B Wright | 2020 | 水科学进展2020，31，4： | 6 |
| 18 | The hormone resistin links obesity to diabetes显示文摘 | Steppan CM Bailey ST Bhat S Brown EJ Banerjee RR Wright CM Patel HR Ahima RS Lazar MA | | 0，，： | 6 |
| 19 | PLEIOTROPIC REGULATORY LOCUS 1 (PRL1) Integrates the Regulation of Sugar Responses with Isoprenoid Metabolism in Arabidopsis显示文摘在植物房间的 isoprenoids 的生合成从 mevalonate (MVA ) 在 cytosol 生产的先锋发生小径并且在由 methylerythritol 4 磷酸盐(MEP ) 的质体,小径,而是很少对协调两条小径的机制被知道。在 Arabidopsis thaliana 为如此的协作发信号的糖的重要性的证据被没有变化,在相关 MEP 小径抄本,蛋白质,或酶活动的层次显示出导出 MEP 的 isoprenoid 产品(叶绿素和类胡萝卜素) 的增加的累积的异种的描述这里提供。这异种被发现是新 loss-of-function 等位基因 PRL1 (多种的规章的地点 1 ) ,编码作为糖的一个全球管理者工作的保存 WD 蛋白质的基因,应力,和荷尔蒙回答,部分地由 SNF1 相关的蛋白质 kinases (SnRK1 ) 的抑制。与在 MVA 小径的主要的规章的酶的 phosphorylation 和 inactivation 的 SnRK1 kinases 的报导角色一致(hydroxymethylglutaryl 辅酶 -- reductase ) ,它的活动或蛋白质层次在 prl1 幼苗被减少。然而,导出 MVA 的结束产品(甾醇) 的累积在变异的幼苗是未改变的。蔗糖补充到野类型的幼苗 phenocopied prl1 变化以 isoprenoid 新陈代谢,建议观察 isoprenoid 显型从增加的糖累积导致 prl1 异种。在摘要, PRL1 看起来与糖,荷尔蒙,和压力回答协调 isoprenoid 新陈代谢。 | Ursula Flores-Perez Jordi Perez-Gil Marta Closa Louwrance R Wright Patricia Botella-Pavia Michael A. Phillips Albert Ferrer Jonathan Gershenzon Manuel Rodriguez-Concepcion | 2010 | Molecular Plant2010，3，1： | 5 |
| 20 | Development of Biomimetic Squid-Inspired Suckers显示文摘 | Jinping Hou Edward Wright Richard H. C. Bonser George Jeronimidis | 2012 | Journal of Bionic Engineering2012，9，4： | 4 |
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