|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Vitamin B complex and vitamin B12 levels after peripheral nerve injury显示文摘The aim of the present study was to evaluate whether tissue levels of vitamin B complex and vitamin B12 were altered after crush-induced peripheral nerve injury in an experimental rat model. A total of 80 male Wistar rats were randomized into one control(n = 8) and six study groups(1, 6, 12, 24 hours, 3, and 7 days after experimental nerve injury; n = 12 for each group). Crush-induced peripheral nerve injury was performed on the sciatic nerves of rats in six study groups. Tissue samples from the sites of peripheral nerve injury were obtained at 1, 6, 12, 24 hours, 3 and 7 days after experimental nerve injury. Enzyme-linked immunosorbent assay results showed that tissue levels of vitamin B complex and vitamin B12 in the injured sciatic nerve were significantly greater at 1 and 12 hours after experimental nerve injury, while they were significantly lower at 7 days than in control group. Tissue level of vitamin B_(12) in the injured sciatic nerve was significantly lower at 1, 6, 12 and 24 hours than in the control group. These results suggest that tissue levels of vitamin B complex and vitamin B_(12) vary with progression of crush-induced peripheral nerve injury, and supplementation of these vitamins in the acute period may be beneficial for acceleration of nerve regeneration. | Idiris Altun Ergül Belge Kurutas | 2016 | Neural Regeneration Research2016，11，5： | 6 |
| 2 | Long-term aspirin pretreatment in the prevention of cerulein-induced acute pancreatitis in rats显示文摘AIM:To investigate the effects of long term pretreatment with low-,medium-and high-dose aspirin(acetylsalicylic acid,ASA) on a model of acute pancreatitis(AP) induced in rats.METHODS:Forty male Wistar rats were used.Three experimental groups,each consisting of eight animals,received low-(5 mg/kg per day),medium-(150 mg/kg per day) and high-dose(350 mg/kg per day) ASA in supplemented pellet chow for 100 d.Eight animals,serving as the AP-control group,and another eight,serving as reference value(RV) group,were fed with standard pellet chow for the same period.After pretreatment,AP was induced in the experimental animals by intraperitoneal administration of cerulein(2 × 50 μg/kg),while the RV group received saline in the same way.Twelve hours after the second injection,the animals were sacrificed.Pancreatic tissue and plasma samples were collected.One part of the collected pancreatic tissues was used for histopathological evaluation,and the remaining portion was homogenized.Cytokine levels [tumor necrosis factor,interleukin(IL)1β,IL-6],hemogram parameters,biochemical parameters(amylase and lipase),nuclear factor-κB,aspirin triggered lipoxins and parameters related to the antioxidant system(malondialdehyde,nitric oxide,hemeoxygenase-1,catalase and superoxide dismutase) were measured.RESULTS:Cerulein administration induced mild pancreatitis,characterized by interstitial edema(total histopathological score of 5.88 ± 0.44vs 0.25 ± 0.16,P < 0.001).Subsequent pancreatic tissue damage resulted in an increase in amylase(2829.71 ± 772.48 vs 984.57 ± 49.22 U/L,P = 0.001) and lipase(110.14 ± 75.84 U/L vs 4.71 ± 0.78 U/L,P < 0.001) in plasma,and leucocytes(6.89 ± 0.48 vs 4.36 ± 0.23,P = 0.001) in peripheral blood.Cytokines,IL-1β(18.81 ± 2.55 pg/μg vs 6.65 ± 0.24 pg/μg,P = 0.002) and IL-6(14.62 ± 1.98 pg/μg vs 9.09 ± 1.36 pg/μg,P = 0.04) in pancreatic tissue also increased.Aspirin pretreatment reduced the increase in the aforementioned parameters to a certain degree and partially improved the histopathological alterations caused by cerulein.No evidence of side effects related to chronic ASA administration(e.g.,inflammation or bleeding) was observed in the gastrointestinal tract in macroscopic and histopathological examination.CONCLUSION:Long term ASA pretreatment could prevent and/or ameliorate certain hematological,serological and histological alterations caused by ceruleininduced AP. | Ibrahim Akyazi Evren Eraslan Ahmet Gülubuk Elif Ergül Ekiz Zeynep L rakli Damla Haktanir Deniz Aktaran Bala Mete zkurt Erdal Matur Mukaddes zcan | 2013 | World Journal of Gastroenterology2013，19，19： | 5 |
| 3 | Association between Helicobacter pylori and liver-to-spleen ratio: a randomized-controlled single-blind study显示文摘 | Zeynal Do?an Levent Filik Bilal Ergül Murat Sarikaya Erdem Akbal | 2013 | European Journal of Gastroenterology & Hepatology2013，，1： | 3 |
| 4 | Assessments on slope instabilities triggered by engineering excavations near a small settlement(Turkey)显示文摘In this study,the mechanisms of slope instabilities triggered by engineering excavations at location of a planned tunnel portal in the northwest region of Turkey were assessed,and stability of the current slopes which has impacts on safety of a settlement(village)and agricultural fields was investigated.In the first stage of the study,in order to identify the geological units and structural properties of the sedimentary rocks in the area,to clarify the mechanisms of instabilities and to characterize discontinuity and rock mass properties field works were conducted.In this content,geotechnical boreholes,geophysical explorations between the boreholes,line surveys to explore discontinuity properties,preparation of slope profiles using topographical techniques and sampling of rock blocks and discontinuity planes were performed.In the second stage,laboratory tests were carried out on the samples to determine the geomechnical properties of the slope forming materials and discontinuities.Then,back analyses of the instabilities were made to assess the responsible shear strength parameters of the geological units during failures by considering laboratory shear test results too.Based on the backanalyses of the failures,the strength properties of the slope debris were estimated,and it has been clarified that the residual shear strength properties are the factors controlling slip mechanism along the beddings.Following the stability analyses,it is understood that a further instability along the mass or bedding planes in the failed and redesigned area are not expected,if the current slope geometry is not changed.However,safety factor calculated for the slope in the debris is 1.1 which is well below the recommended value in the literature.The minimum safety factor for currently stable slopes which were cut at the eastern part of the failed area is 1.22 which is also less than that suggested in literature.Some remedial measures such as mini-pile or slope flattening are suggested after analyses to increase the factor of safety for this part below the settlement. | TUNCAY Ergün | 2018 | Journal of Mountain Science2018，15，1： | 2 |
| 5 | The Efficacy of Two‐Week Quadruple First‐Line Therapy with Bismuth, Lansoprazole, Amoxicillin, Clarithromycin on H elicobacter pylori Eradication: A Prospective Study显示文摘 | Bilal Ergül Zeynal Do?an Murat Sarikaya Levent Filik | 2013 | Helicobacter2013，，6： | 2 |
| 6 | Dose-dependent stimulatory effect of human growth hormone on the strength and collagen deposition of colonic anastomoses in the rat显示文摘 | CHRISTENSEN H FLYVBJ ERG A | 1992 | Acta Endocrinolgica1992，126，： | 1 |
| 7 | Agglomeration characteristics of alumina sand-straw ash mixtures at elevated temperatures显示文摘 | Ghaly A E Ergüdenler A Laufer E | 1993 | Biomass and Bioenergy1993，5，： | 1 |
| 8 | Growth-associated phosphoprotein expression is increase in the supragranular region of the dentate gyrus following pilo-carpine-induced seizrues in rats显示文摘 | Naffah-Mazzacoratti MG Funke MG Sanabria ERG | | 0，，02： | 1 |
| 9 | Analysis of dielectric photonic-crystal problems with MLFMA and schur-complement preconditioners显示文摘 | Ergül O Malas T Gürel L | 2011 | Lightwave Technology2011，29，6： | 1 |
| 10 | The local vascular to lerancetoan in travenou s in fusion of a con en trated glu tam in e solu tion in Icu patients显示文摘 | Berg A Forsb erg E W emerm an J | 2002 | C lin Nutr2002，21，2： | 1 |
| 11 | The formalin test: an evaluation of the method 显示文摘 | Tjolsen A B erge OG Hunskaar S | 1992 | Pain1992，51，1： | 1 |
| 12 | Multiuser detection using genetic in algorithm in CDMA communications systems显示文摘 | Ergün C Hacioglu K | 2000 | IEEE Transactions on Communication2000，48，8： | 1 |
| 13 | Vulvar syringoma exacerbated during pregnancy显示文摘 | Cem Turan Mustafa Ugur Lale Kutluay Selahattin Kükner Tülin Dabakoglu Tugrul Aydogdu Yusuf Ergün Omer Cobanoglu | 1996 | European Journal of Obstetrics and Gynecology1996，，1： | 1 |
| 14 | SMP concept for the new regulatory framework显示文摘 | ] ERG | 2005 | ERG Working Paper2005，，3： | 1 |
| 15 | Cryptosporidiosis in immuno compromised patients in a Turkish university hospital显示文摘 | Arikan S Ergüven S Akyn Y | 1999 | Acta Mi crobiol Immunol Hung1999，46，1： | 1 |
| 16 | Hallmarks of cancer: the next generation显示文摘 | Hanahan D Weinl~erg R A | 2011 | Cell2011，144，5： | 1 |
| 17 | Prophylactic antibiotic use in pediatric burn units显示文摘 | Ergün O Celik A Ergün G | | 0，，： | 1 |
| 18 | Aller- gic rhinitis and its impact on asthma显示文摘 | Bousquet J Van (}auwent)erge P Khaltaev N | 2001 | J Allergy Clin Immunol2001，108，5： | 1 |
| 19 | The CT frequencies of various non-traumatic acute abdominal emergencies in hemodialysis,peritoneal dialysis patients and the general population显示文摘 | Ergün T Lakadamyal H | | 0，，01： | 1 |
| 20 | Vascular endothelial growth factor,a possible paraerine growth factor in human acute myeloid leukemia显示文摘 | Fiedler W Graeven U Ergün S at al | 1997 | Blood1997，89，6： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员