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| 1 | Brain metastasis of hepatocellular carcinoma:A case report and review of the literature显示文摘Hepatocellular carcinoma (HCC) is one of the most frequent malignancies in the world. It is more common in far eastern countries and relatively rare in the United States and western European countries where at autopsy it accounts for only 1-2% of malignant rumors, The disease is usually manifested in the the 6^th and 7^th decade of life. HCC is one of the highly malignant neoplasms, Extrahepatic metastases are seen in 64% of patients with HCC. The lungs, regional lymph nodes, kidney, bone marrow and adrenals are common sites of HCC metastasis^[1-3], But, metastasis to brain and skull is extremely rare. Table I shows some of the reported cases of HCC with brain metastasis. These case reports reaffirms the complex and multidisciplinary care of these patients^[4-5]. | Bilge Tunc Levent Filik Irsel Tezer-Filik Burhan Sahin | 2004 | World Journal of Gastroenterology2004，10，11： | 4 |
| 2 | Association between Helicobacter pylori and liver-to-spleen ratio: a randomized-controlled single-blind study显示文摘 | Zeynal Do?an Levent Filik Bilal Ergül Murat Sarikaya Erdem Akbal | 2013 | European Journal of Gastroenterology & Hepatology2013，，1： | 3 |
| 3 | The Efficacy of Two‐Week Quadruple First‐Line Therapy with Bismuth, Lansoprazole, Amoxicillin, Clarithromycin on H elicobacter pylori Eradication: A Prospective Study显示文摘 | Bilal Ergül Zeynal Do?an Murat Sarikaya Levent Filik | 2013 | Helicobacter2013，，6： | 2 |
| 4 | Use of the molybdenum-thiocyanate-rhodamine-6G ternary complex for spectrophotometric molybdenum determination without extraction显示文摘 | Hayati Filik Esma Tatem Resat Apak | 2004 | Analytiea Chimica Acta2004，505，： | 1 |
| 5 | Effect of interferon and ribavirin combined with amantadine in interferon and ribavirin non-responder patients with chronic hepatitis C (genotype 1)显示文摘AIM: To evaluate the efficacy of amantadine plus interferonalpha and ribavirin in non-responder patients with chronic hepatitis C.METHODS: Twenty-six non-responder patients received the regimen of IFN-α-2a at a dose of 6 million units three times a week, 1 000-1 200 mg of ribavirin daily, and 200 mg of amantadine daily in divided doses over 48 wk. After the end of treatment, at the 72nd wk, a sustained viral response rate was determined.RESULTS: An early (after 12 wk of therapy) response was seen in 34.6% (9/26) of patients. Response rate at the 24th wk was 42.3% (11/26). End of treatment response (ETR) was 53.8% (14/26). Sustained viral response (SVR) was 42.3% (11/26). There was a statistically significant difference between 0 and 12 wk (P = 0.04), 0 and 24 wk (P = 0.01), 0 and 48 wk (P = 0.00), and 0 and 72 wk (P = 0.001). No patient had severe adverse effects during the treatment.CONCLUSION: Combination regimen of interferon-α,ribavirin and amantadine can enhance sustained viral response on IFN-α and ribavirin non-responder patients with HCV. Triple therapy with amantadine should be evaluated in further studies. | Dilek Oguz Bahattin Cicek Levent Filik Bulent Odemis Mesut Kilic Engin Altintas Neslihan Zengin Emin Altiparmak | 2005 | World Journal of Gastroenterology2005，11，4： | 1 |
| 6 | Design and Evaluation of V-shaped Arrays for 2-D DOA Estimation 显示文摘 | Filik T Tuncer T E | 2008 | IEEE Conference on Acoustics Speech and Signal Processing2008，4，2： | 1 |
| 7 | Preconcentration and speciation of chromium using a melamine based polymeric sequestering succinic acid resin: its application for Cr (VI) and Cr (III) determination in wastewater 显示文摘 | Dog-utan M Filik H Tor I | 2003 | Talanta2003，59，5： | 1 |
| 8 | Behcet' s disease and colonic diverticula显示文摘 | Filik L | 2010 | Dig Surg2010，26，6： | 1 |
| 9 | An unusual complication of nasogastric tube显示文摘 | Biyiko glu I Ktklti S Filik L | 2012 | Acta Gastroenterol Belg2012，75，4： | 1 |
| 10 | Monocyte chemotactic protein-1 gene polymorphism and spontaneous bacterial peritonitis显示文摘I read with great interest the article by Gbele et al published in issue 44 of World J Gastroenterol 2009.The results of their study indicate that-2518 Monocyte chemotactic protein-1(MCP-1)genotype AA is a risk factor for spontaneous bacterial peritonitis in patients with alcoholic cirrhosis.However,there are some items that need to be discussed. | Levent Filik | 2010 | World Journal of Gastroenterology2010，16，7： | 1 |
| 11 | Spectrophotometric determination of paracetamol in urine with tetrahydroxycalix arene as acoupling reagent and preconcentration with triton X-114 using cloud point extraction 显示文摘 | Filik H Sener I Cekic S D | 2006 | Chemical & Pharmaceutical Bulletin2006，54，6： | 1 |
| 12 | CRP and pediatric ulcerative colitis显示文摘 | Filik L | 2012 | J Crohns Colitis2012，6，2： | 1 |
| 13 | Spectrophotometric determination of paracetamol in urine with tetrahydroxycalixarene as a coupling reagent and preconcentration with Triton X-114 using cloud point extraction显示文摘 | Filik H Sener I Cekic S D | 2006 | Chem Pharm Bull2006，54，6： | 1 |
| 14 | Hypophosphatemia in living liver donors显示文摘 | Filik L Karakayali H Dalgi A | 2006 | Transplant Proc2006，38，2： | 1 |
| 15 | Severe Legionella pneumophila pneumonia following infliximab therapy in a patient with Crohn's dis- ease显示文摘 | Bigel F Jnrgens M Filik L | 2009 | Inflamm Bowel Dis2009，15，： | 1 |
| 16 | Determination of zinc in pharmaceuticals by first derivative UV-visible spectrophotometry显示文摘 | GUMUS G FILIK H DEMIRATA B | 2005 | Anal Chim Acta2005，547，： | 1 |
| 17 | Behcet's disease and colonic diverticula 显示文摘 | Filik I | 2010 | Dig Surg2010，26，6： | 1 |
| 18 | Determination of Sulfite in Water and Dried Fruit Samples by Dispersive Liquid–Liquid Microextraction Combined with UV–Vis Fiber Optic Linear Array Spectrophotometry显示文摘 | Hayati Filik Gamze ?etinta? | 2012 | Food Analytical Methods2012，，6： | 1 |
| 19 | The effect of ion energy on the deposition of amorphous carbon phosphide films 显示文摘 | Pearce S R J Filik J May P W | 2003 | Diamond Relat Mater2003，12，37： | 1 |
| 20 | Clinical and laboratory features of sportaneous bacterial peritoritis显示文摘 | Filik L Unal S | 2004 | East African Medical Journal2004，81，9： | 1 |
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