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| 1 | Pacemaker therapy in very elderly patients: survival and prognostic parameters of single center experience显示文摘Background Permanent pacing is the therapy of choice for treating severe and/or symptomatic bradyarrhythmias. The number of very elderly patients receiving pacemakers is increasing and little is known about survival in this specific subgroup. This study is aimed at assessing the actual survival of patients requiring pacing therapy at age > 85 years and investigating variables associated with death. Methods Between 2010 and 2017, 572 patients aged ≥ 85 years underwent pacemaker implantation for conventional bradycardia indications in Department of Cardiology, S. Chiara Hospital, Italy. Results Thirty percent of patients were ≥ 90-year-old and comorbidities were frequent. Fifty-seven percent of patients required pacing for prognostic reasons(acquired atrioventricular block), and the remaining for relief of bradycardia symptoms. A dual-chamber pacemaker was implanted in 34% of patients. The 5-year survival was 45%(standard error: 3%), and the 8-year survival was 26%(standard error: 4%). The risk of death was similar in patients who received pacemaker for symptom relief and for prognostic reasons in the overall population(HR = 1.19, 95% CI: 0.93–1.52, P = 0.156), as well as in the ≥ 90-year-old group(HR = 1.39, 95% CI: 0.92–2.11, P = 0.102). At multivariate analysis, following variables were associated with death: higher age, lower ejection fraction, dementia/dysautonomia and diagnosis of cancer. The pacing indication and the implantation of a single chamber pacemaker were not associated with worse prognosis. Conclusions This study showed a good life expectancy in patients aged ≥ 85 years who received a pacemaker. Strong risk factors for all-cause death were non-cardiac. Pacemaker therapy seems a clinically effective therapeutic option to improve survival and to control bradyarrhythmia-related symptoms in very elderly patients. | Massimiliano Marini Marta Martin Michela Saltori Silvia Quintarelli Filippo Zilio Fabrizio Guarracini Alessio Coser Sergio Valsecchi Roberto Bonmassari | 2019 | Journal of Geriatric Cardiology2019，16，12： | 3 |
| 2 | Condensation inside and outside smooth and enhanced tubes — a review of recent research显示文摘 | A. Cavallini G. Censi D. Del Col L. Doretti G.A. Longo L. Rossetto C. Zilio | 2003 | International Journal of Refrigeration2003，，4： | 2 |
| 3 | The fluorinated olefin R- 1234ze(Z) as a high-temperature heat pmnping refrigerant 显示文摘 | Brown J S Zilio C Cavallini A | 2009 | International Journal of Refrigeration2009，32，6： | 1 |
| 4 | Thermodynamic analysis of different two-stage transcritical carbon dioxide cycles显示文摘 | Luca Cecchinato Manuel Chiarello Marco Corradi Ezio Fornasieri Silvia Minetto Paolo Stringari Claudio Zilio | 2008 | International Journal of Refrigeration2008，，5： | 1 |
| 5 | OPAl requires mitofusin 1 to promote mitochondrial fusion 显示文摘 | Cipolat S de Brito OM Dal Zilio B | 2004 | Proc Natl Acad Sci USA2004，101，15： | 1 |
| 6 | GDP and environment pressure: The role of energy in Latin America and the Caribbean显示文摘 | Mariana Zilio Marina Recalde | 2011 | Energy Policy2011，，12： | 1 |
| 7 | Condensation of the low GWP refrigerant HFC152a inside a brazed plate heat exchanger显示文摘 | LONGO G A ZILIO C RIGHETTI G | 2015 | Experimental Thermal and Fluid Science2015，68，： | 1 |
| 8 | Performance of sali vary cortisol in the diagnosis of Cushing's syndrome, adrenal inciden?talorna , and adrenal insufficiency显示文摘 | Cecca to F Barbot M Zilio M et a1 | 2013 | EurJ Endocrinol2013，169，1： | 1 |
| 9 | Experimental as- sessment of the low GWP refrigerant I-IFO-1234ze(Z) for high temperature heat pumps 显示文摘 | Longo G A Zilio C Righetti G | 2014 | Experimental Thermal and Fluid Science2014，57，3： | 1 |
| 10 | Superhydrophobic Surfaces Fabricated by Nanoimprint Lithography显示文摘 | A Pozzato S Dal Zilio G Fois | 2006 | Microelectronic Engineering2006，83，： | 1 |
| 11 | OPAl requires mitofusin 1 to promote mitochondrial fusion 显示文摘 | Cipolat S Martins de Brito O Dal Zilio B | 2004 | Proc Natl Acad Sci USA2004，101，15： | 1 |
| 12 | Myeloid-derived suppressor cell heterogeneity and subset definition显示文摘 | Peranzoni E Zilio S Marigo I | 2010 | Curr Opin Immunol2010，22，2： | 1 |
| 13 | OPA1 re-quires mitofusin 1 to promote mitochondrial fusion显示文摘 | Cipolat S Martins de Brito O Dal Zilio B | | 0，，： | 1 |
| 14 | Experimental air heat transfer and pressure drop through copper foams 显示文摘 | Mancin S Zilio C Diani A | 2012 | Experimental Thermal and Fluid Science2012，36，： | 1 |
| 15 | Air forced convection through metal foams: experimental results and modeling 显示文摘 | Mancin S Zilio C Diani A | 2013 | International Journal of Heat and Mass Transfer2013，62，： | 1 |
| 16 | Pressure drop during air flow in aluminum foams显示文摘 | MANCIN S ZILIO C CAVALLINI A | 2010 | Intern-ational Journal of Heat and Mass Transfer2010，53，1516： | 1 |
| 17 | Are modern economies following a sustainable energy consumption path? 显示文摘 | Marina Yesiea Recalde Carina Guzowski Mariana Ines Zilio | | Energy for Sustainable Development0，2014，19： | 1 |
| 18 | Electrochemical treatment of tan-nery wastewater using Ti/Pt and Ti/Pt/Ir electrodes显示文摘 | Szpyrkowicz L Naumczyk J Zilio G F | | 0，，02： | 1 |
| 19 | Heat transfer performance of aluminum foams显示文摘 | Mancin S Zilio C Rossetto L | | Journal of Heat Transfer0，133，06： | 1 |
| 20 | Myeloid-deriw~d suppressor cell het- erogeneity and subset definition 显示文摘 | Peranzoni E Zilio S Mza'igo I | 2010 | Curt Opin lnumauno2010，22，2： | 1 |
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