2篇
您的检索式：作者名="Sergio Valsecchi"
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| 1 | Pacemaker therapy in very elderly patients: survival and prognostic parameters of single center experience显示文摘Background Permanent pacing is the therapy of choice for treating severe and/or symptomatic bradyarrhythmias. The number of very elderly patients receiving pacemakers is increasing and little is known about survival in this specific subgroup. This study is aimed at assessing the actual survival of patients requiring pacing therapy at age > 85 years and investigating variables associated with death. Methods Between 2010 and 2017, 572 patients aged ≥ 85 years underwent pacemaker implantation for conventional bradycardia indications in Department of Cardiology, S. Chiara Hospital, Italy. Results Thirty percent of patients were ≥ 90-year-old and comorbidities were frequent. Fifty-seven percent of patients required pacing for prognostic reasons(acquired atrioventricular block), and the remaining for relief of bradycardia symptoms. A dual-chamber pacemaker was implanted in 34% of patients. The 5-year survival was 45%(standard error: 3%), and the 8-year survival was 26%(standard error: 4%). The risk of death was similar in patients who received pacemaker for symptom relief and for prognostic reasons in the overall population(HR = 1.19, 95% CI: 0.93–1.52, P = 0.156), as well as in the ≥ 90-year-old group(HR = 1.39, 95% CI: 0.92–2.11, P = 0.102). At multivariate analysis, following variables were associated with death: higher age, lower ejection fraction, dementia/dysautonomia and diagnosis of cancer. The pacing indication and the implantation of a single chamber pacemaker were not associated with worse prognosis. Conclusions This study showed a good life expectancy in patients aged ≥ 85 years who received a pacemaker. Strong risk factors for all-cause death were non-cardiac. Pacemaker therapy seems a clinically effective therapeutic option to improve survival and to control bradyarrhythmia-related symptoms in very elderly patients. | Massimiliano Marini Marta Martin Michela Saltori Silvia Quintarelli Filippo Zilio Fabrizio Guarracini Alessio Coser Sergio Valsecchi Roberto Bonmassari | 2019 | Journal of Geriatric Cardiology2019，16，12： | 3 |
| 2 | Antiarrhythmic Effect of Reverse Ventricular Remodeling Induced by Cardiac Resynchronization Therapy显示文摘 | Luigi Di Biase Maurizio Gasparini Maurizio Lunati Massimo Santini Maurizio Landolina Giuseppe Boriani Antonio Curnis Mario Bocchiardo Antonio Vincenti Alessandra Denaro Sergio Valsecchi Andrea Natale Luigi Padeletti | 2008 | Journal of the American College of Cardiology2008，，18： | 1 |
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