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| 1 | 2016 Chinese expert consensus and guidelines for the diagnosis and treatment of papillary thyroid microcarcinoma显示文摘The incidence of papillary thyroid carcinoma(PTC)has exponentially increased in recent years.Papillary thyroid microcarcinoma(PTMC)accounts for the majority of the reported cases of PTC.The debates and crucial issues in PTMC management have received researchers'attention.To further improve the clinical management of PTMC in China, | Ming Gao Minghua Ge Qinghai Ji Ruochuan Cheng Hankui Lu Haixia Guan Li Gao Zhuming Guo Tao Huang Xiaoming Huang Xiaoming Li Yansong Lin Qinjiang Liu Xin Ni Yi Pan Jianwu Qin Zhongyan Shan Hui Sun Xudong Wang Zhengang Xu Yang Yu Daiwei Zhao Naisong Zhang ShengZhang Ying Zheng Jingqiang Zhu Dapeng Li Xiangqian Zheng 无 | 2017 | Cancer Biology & Medicine2017，14，3： | 23 |
| 2 | 2017 Chinese expert consensus on the clinical application ofserum marker for thyroid cancer显示文摘In recent years, the clinical incidence of thyroid cancer has been increasing year by year, and its risk assessment and clinical management methods have also been accordingly modified and constantly improved. There are great differences between the clinical diagnostic and therapeutic modes and disease management of thyroid cancer employed by various medical institutions in China, particularly with regard to the clinical application of serum marker of thyroid cancer. To this end, the China Anti-Cancer Association Thyroid Cancer Specialized Committee Chinese Association of Thyroid Oncology organized this compilation of ExpertConsensus on Clinical Application of Serum Marker of Thyroid Cancer to help and impel relevant clinical institutions and professionals to standardize clinical diagnosis, treatment, and long-term management of thyroid cancer, and to properly utilize the serum marker for scientific auxiliary clinical diagnosis and assessment of thyroid cancer before and after operation. | Ming Gao Minghua Ge Qinghai Ji Ruochuan Cheng Hankui Lu Haixia Guan Wei Cui Li Gao Zairong Gao Lin Guo Zhuming Guo Tao Huang Xiaoming Huang Yansong Lin Qinjiang Liu Xin Ni Jianwu Qin Li Ren Zhongyan Shan Hui Sun Xudong Wang Zhengang Xu Yang Yu Bin Zhang DaiweiZhao Ying Zheng Jingqiang Zhu Xiangqian Zheng 无 | 2018 | Cancer Biology & Medicine2018，15，4： | 3 |
| 3 | Neck dissection for recurrent and persistent lymph nodes of nasopharyngeal carcinoma after radiotherapy: effect and choice显示文摘目的将在放射疗法以后与周期性、坚持的淋巴节点为鼻咽的癌的病人调查最好的外科的模式。有在放射疗法以后的周期性、坚持的淋巴节点的鼻咽的癌的 88 个病人的临床的数据回顾地被分析的方法。在层次之中的深奥淋巴节点和关系的层次被分析;幸存率和包括激进的颈解剖(RND ) 的外科的模式的周期性的率,修改的激进的颈解剖(MRND ) ,选择的颈解剖(SND ) ,和淋巴节点切除术(LNR ) 被分析;手术后的放射疗法的角色被评估。周期性、坚持的淋巴节点主要在水平 II 定位了的结果( 1 )(55.6%和58.6%,分别地),下次是水平 III 并且很少在水平 IV , V ,并且我,而是层次 IV 的数字, V ,并且我与忍受癌症的淋巴结是相对多于临床的测量的。(2 ) 通常,有涉及水平 III 和 IV 的淋巴节点的病人把另外的层次同时深奥;百分比分别地是 63.6% 和 88.9% 。然而,在水平 II 和 V 的淋巴节点主要被孤立。(3 )5 年的幸存率和整个组的周期性的率分别地是 42.77% 和 22.7% 。(4 ) RND, MRND, SND,和 LMR 组的 5 年的幸存率分别地是 39.75% , 60.00% , 37.87% ,和 44.10% ;差别是不足道的(木头等级 = 1.0, P = 0.8011 ) ;在广泛、本地的外科组之间的周期性的率是不足道的(X 2= 0.470, P = 0.493 ) 。(5 ) 有或没有手术后的放射疗法的病人的 5 年的幸存率分别地是 39.06% 和 45.26% ;差别是不足道的(木头等级 = 0.06, P = 0.8138 ) 。当周期性、坚持的淋巴结是超过一水平时,广泛的外科被推荐的结论包含了或很大或不可移动不那样, SND 应该被执行,手术后的放射疗法如果必要是重要赔偿。 | Liangping Xia Zongyuan Zeng Zhuming Guo Guifang Guo Bei Zhang Huijuan Qiu Feifei Zhou | 2009 | The Chinese-German Journal of Clinical Oncology2009，8，2： | 3 |
| 4 | Performance Optimization for an Irreversible Quantum Stirling Cooler显示文摘The purpose of this paper is to study the optimal performance for an irreversible quantum Stirling cooler with heat leak and other irreversible losses. The relationship between the optimal cooling load and the coefficient of performance (COP) for the quantum Stirling cooler is derived. The maximum cooling load and the corresponding COP, as well as the maximum coefficient of performance and the corresponding cooling load are obtained. The experimental observation for the optimal region is provided. | Zhuming Huang Feng Wu Lingen Chen Chih Wu Fangzhong Guo | 2002 | Journal of Thermal Science2002，11，3： | 1 |
| 5 | Using a linear stapler for pharyngeal closure in total laryngectomy显示文摘 | Xinrui Zhang Zhimin Liu Quan Li Xuekui Liu Hao Li Weiwei Liu Qiuli Li Zhuming Guo Zongyuan Zeng | 2013 | European Archives of Oto-Rhino-Laryngology2013，，4： | 1 |
| 6 | Circulating MicroRNA Profiles as Potential Biomarkers for Diagnosis of Papillary Thyroid Carcinoma显示文摘 | Shuang Yu Yuanyuan Liu Jingsong Wang Zhuming Guo Quan Zhang Fengyan Yu Yunjian Zhang Kai Huang Yanbing Li Erwei Song Xi-long Zheng Haipeng Xiao | 2012 | The Journal of Clinical Endocrinology & Metabolism2012，，6： | 1 |
| 7 | Intratumoral Bacteria Dysbiosis Is Associated with Human Papillary Thyroid Cancer and Correlated with Oncogenic Signaling Pathways显示文摘Emerging evidence suggests that microbial dysbiosis plays vital roles in many human cancers.However,knowledge of whether the microbial community in thyroid tumor is related to tumorigenesis remains elusive.In this study,we aimed to explore the microbial community in thyroid tissues and its contribution to papillary thyroid cancer(PTC).In parallel,we performed microbial profiling and transcriptome sequencing in the tumor and adjacent normal tissues of a large cohort of 340 PTC and benign thyroid nodule(BTN)patients.Distinct microbial signatures were identified in PTC,BTN,and their adjacent nontumor tissues.Intra-thyroid tissue bacteria were verified by means of bacteria staining,fluorescence in situ hybridization,and immunoelectron microscopy.We found that 17 bacterial taxa were differentially abundant in PTC compared with BTN,which included enrichment in PTC of the pathobionts Rhodococcus,Neisseria,Streptococcus,Halomonas,and Devosia,and depletion of the beneficial bacteria Amycolatopsis.These differentially abundant bacteria could differentiate PTC tumor tissues(PTC-T)from BTN tissues(BTN-T)with an area under the curve(AUC)of 81.66%.Microbial network analysis showed increased correlation strengths among the bacterial taxa in PTC-T in comparison with BTN-T.Immunefunction-corresponding bacteria(i.e.,Erwinia,Bacillus,and Acinetobacter)were found to be enriched in PTC with Hashimoto’s thyroiditis.Moreover,our integrative analysis revealed that the PTC-enriched bacteria had a positive association with key PTC-oncogenic pathway-related genes,including BRAF,KRAS,IRAK4,CTNNB1,PIK3CA,MAP3K7,and EGFR.In conclusion,our results suggest that intratumor bacteria dysbiosis is associated with the thyroid tumorigenesis and oncogenic signaling pathways of PTC. | Shuang Yu Yanqiang Ding Xuejie Wang Siu Kin Ng Siting Cao Weixin Liu Zhuming Guo Yubin Xie Shubin Hong Lixia Xu Xiaoxing Li Jie Li Weiming Lv Sui Peng Yanbing Li Joseph J.Y.Sung Jun Yu Haipeng Xiao | 2023 | Engineering2023，，9： | 0 |
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