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| 1 | Tumor suppressor miR-128-3p inhibits metastasis and epithelial-mesenchymal transition by targeting ZEB1 in esophageal squamous-cell cancer显示文摘MicroRNAs (miRNAs ) 是在 post-transcriptional 层次调整多重生物功能的一些短 RNA,例如 tumorigenic 过程,煽动性的损害和房间 apoptosis。(ZEB1 ) 锌手指电子盒子有约束力的 homeobox 因素 1 是上皮间充质的转变(EMT ) 的一个关键调停人。它包括人的食道的有鳞房间的癌(ESCC ) 导致各种各样的癌症的恶意的前进。在这研究,我们发现 miR-128-3p 由使用 PCR 是在 ESCC 纸巾和房间的 downregulated。而且, miR-128-3p 的下面调整的表示被证明与 ESCC 病人的差的预后被联系并且可能被认为是一个独立预示的因素。然后,我们在 ESCC 房间检验了 miR-128-3p 的角色,并且发现 miR-128-3p 能在 vitro 压制房间迁居和侵略。而且, ZEB1 被证实是由酶记者试金的 miR-128-3p 的一个直接目标。营救实验证明 EMT 被 miR-128-3p 经由 ZEB1 的抑制调整。一起拿所有,我们断定 miR-128-3p 压制 EMT,经由 ZEB1 的转移,和 miR-128-3p 可以是在 ESCC 的一个批评调停人。 | Lili Zhao Rui Li Shanling Xu Yi Li Pei Zhao Wei Dong Zhenjun Liu Qian Zhao Bo Tan | 2018 | Acta Biochimica et Biophysica Sinica2018，50，2： | 21 |
| 2 | Exploitation of Bi2O2Se/graphene van der Waals heterojunction for creating efficient photodetectors and short-channel field-effect transistors显示文摘The formation of heterojunction within solid-state devices enables them with eventually high performances,but provides a challenge for material synthesis and device fabrication because strict conditions such as lattice match are needed.Herein,we show a facile method to fabricate a van der Waals(vdW)heterojunction between two-dimensional(2D)bismuth oxyselenide(Bi2O2Se)and graphene,during which the graphene is directly transferred to the Bi2O2Se and served as a lowcontract-resistant electrode with small work function mismatch(~50 meV).As an optoelectronic device,the Bi2O2Se/graphene vdW heterojunction allows for the efficient sensing toward 1200-nm incident laser.Regarding the application of fieldeffect transistors(FETs),the short-channel(50 nm)sample can be synthesized by utilizing these two 2D materials(ie,channel:Bi2O2Se;drain/source terminal:graphene)and the n-type characteristic can be observed with the accordant field modulation.It is confirmed that we show a simple way to prepare the vdW heterojunction which is aiming to the high-performance applications among optoelectronics and FETs. | Congwei Tan Shipu Xu Zhenjun Tan Luzhao Sun Jinxiong Wu Tianran Li Hailin Peng | 2019 | InfoMat2019，1，3： | 8 |
| 3 | Growth of 12-inch uniform monolayer graphene film on molten glass and its application in PbI2-based photodetector显示文摘Direct growth of large area uniform graphene on functional insulating materials is essential for engineering versatile applications of graphene. However, the existing synthesis approaches can hardly avoid the generation of non-uniform multilayer graphene along the gas flow direction, affording huge challenges for further scaling up. Herein, by exploiting the molten state of soda-lime glass, we have accomplished the direct growth of large area uniform (up to 30 cm × 6 cm) graphene via a facile chemical vapor deposition route on low cost soda-lime glass. The use of molten glass eliminates the chemically active sites (surface corrugations, scratches, defects), and improves the mobility of carbon precursors, affording uniform nucleation and growth of monolayer graphene. Intriguingly, thus-obtained graphene acts as an ideal coating layer for the surface crystallographic modification of soda-lime glass, making it epitaxy substrates for synthesizing high-quality PbI2 nanoplates and continues films. Accordingly, a prototype photodetector was fabricated to present excellent photoelectrical properties of high responsivity (~ 600 on/off current ratio) and fast response speed (18 μs). This work hereby paves ways for the batch production and the direct applications of graphene glass as platforms for constructing high performance electronic and optoelectronic devices. | Zhaolong Chen Haina Ci Zhenjun Tan Zhipeng Dou Xu-dong Chen Bingzhi Liu Ruojuan Liu Li Lin Lingzhi Cui Peng Gao Hailin Peng Yanfeng Zhang Zhongfan Liu | 2019 | Nano Research2019，12，8： | 1 |
| 4 | Xiaoping Dong,China CDC’s Chief Expert of Virology显示文摘Xiaoping Dong is the Chief Expert of Virology of China CDC,Adjunct Professor at Beijing University and Xi’an Jiaotong University,and Adjunct Principal Investigator(PI)at the Chinese Academy of Science and China Academy of Chinese Medical Sciences.He is a syndic of the Chinese Society of Microbiology and the Head of the Group of Medical Virology.During his roughly 40-year career,he has dedicated himself to the studies of medical virology and molecular biology. | Yu Chen Peter Hao Nankun Liu Zhenjun Li Jingjing Xi Feng Tan | 2021 | China CDC weekly2021，3，19： | 0 |
| 5 | Jiaqi Ma, China CDC’s Chief Expert of Health Information显示文摘Jiaqi Ma is the Chief Expert of Health Information of China CDC and has been engaged in public health informatics for more than 30 years.As a leading figure,he put forward creative information construction concepts at multiple key periods and led his team to achieve the establishment of the Chinese Information System for Disease Control and Prevention(CISDCP),which represented a major development of China’s public health informatics. | Peter Hao Nankun Liu Zhenjun Li Jingjing Xi Feng Tan | 2020 | China CDC weekly2020，2，38： | 0 |
| 6 | Wenhua Zhao, China CDC’s Chief Expert of Nutrition显示文摘Wenhua Zhao is the China CDC’s Chief Expert of Nutrition and the Chairwoman of the Society for Noncommunicable Diseases(NCDs)Control and Prevention,Chinese Preventive Medicine Association(CPMA).She has been working in public health for almost four decades and has expertise in nutrition,epidemiology,and NCD control and prevention. | Peter Hao Nankun Liu Zhenjun Li Jingjing Xi Feng Tan | 2020 | China CDC weekly2020，2，39： | 0 |
| 7 | Zunyou Wu,China CDC’s Chief Expert of Epidemiology显示文摘Zunyou Wu is the Chief Expert of Epidemiology of China CDC,an Adjunct Professor of Epidemiology at the University of California,Los Angeles(UCLA),and a member of the UNAIDS Evaluation Expert Advisory Committee.He has made significant contributions in the field of infectious diseases control,particularly for HIV/AIDS,severe acute respiratory syndrome(SARS),and coronavirus disease 2019(COVID-19). | Peter Hao Ying Zhang Zhenjun Li Jingjing Xi Feng Tan | 2020 | China CDC weekly2020，2，34： | 0 |
| 8 | Liubo Zhang, China CDC’s Chief Expert of Disinfection显示文摘Liubo Zhang is the Chief Expert of Disinfection of China CDC and has been devoted to public health and preventive medicine since graduating from Wuhan Medical College in 1983.Over the past 37 years,he has been engaged in many fields such as epidemic control,infectious disease prevention and control,and disinfection and hospital infection control.Especially in the past 20 years,he has made outstanding contributions to these fields.Zhang has participated in the prevention and control of major infectious diseases such as the severe acute respiratory syndrome(SARS)epidemic and laboratory infections,human infection with highly pathogenic avian influenza,hand-foot-mouth disease,influenza A(H1N1),coronavirus disease 2019(COVID-19),etc.He was responsible for the development of disinfection technical guidelines and on-site guidance for these diseases. | Peter Hao Yu Chen Zhenjun Li Jingjing Xi Feng Tan | 2020 | China CDC weekly2020，2，36： | 0 |
| 9 | Guizhen Wu, China CDC’s Chief Expert of Biosafety显示文摘Guizhen Wu,China CDC’s Chief Expert of Biosafety,has been working for nearly four decades in the field of public health emergencies and laboratory biosafety.Wu is the major planner and promoter of the laboratory biosafety management system in China.In 2018 as the Chairwoman,Wu hosted the 13th Asia-Pacific Biosafety Association(A-PBA)Biosafety Conference held in Beijing,which was the first international biosafety conference held in China.She was elected as the President of A-PBA on September 19,2019. | Peter Hao Yu Chen Zhenjun Li Jingjing Xi Feng Tan | 2020 | China CDC weekly2020，2，37： | 0 |
| 10 | Xu Su,China CDC’s Chief Expert of Radiation Protection显示文摘Xu Su is the major leader of radiation protection in China and has been honored and awarded several times,has published more than 280 research papers,and has been the Director of the National Institute for Radiological Protection(NIRP)of China CDC and the Professor and Executive Director of the Chinese Center for Medical Response to Radiation Emergency from 2002 to 2017. | Peter Hao Yu Chen Zhenjun Li Jingjing Xi Feng Tan | 2020 | China CDC weekly2020，2，29： | 0 |
| 11 | Chengye Sun,China CDC’s Chief Expert of Poison Control显示文摘In July 1985,Chengye Sun graduated from Henan Medical University and became a physician in a hospital.In 1988,he entered the Chinese Academy of Preventive Medical Sciences for postgraduate studies on occupational medicine,which helped him become a public health professional.The shift from being a clinician to a public health worker helped him realize how external factors could act as strong drivers on human health. | Yu Chen Peter Hao Nankun Liu Zhenjun Li Jingjing Xi Feng Tan | 2021 | China CDC weekly2021，3，18： | 0 |
| 12 | Yiming Shao, China CDC’s Chief Expert of AIDS显示文摘Yiming Shao is China CDC’s Chief Expert of AIDS,the Chairman of the Academic Committee of the National Center for AIDS/STD Control and Prevention(NCAIDS),and the Vice President of the Chinese Microbiology Society(CMS)after chairing the CMS’s Virology Committee(2001–2010).Shao graduated from Qingdao Medical College in 1983 and pursued a PhD at the Institute of Virology in the Chinese Academy of Preventive Medicine.He participated in the diagnosis of China’s first cases of HIV and AIDS,isolated China’s first HIV-1 virus,and developed the initial HIV diagnostic reagents for the country. | Peter Hao Nankun Liu Zhenjun Li Jingjing Xi Feng Tan | 2020 | China CDC weekly2020，2，40： | 0 |
| 13 | Weiping Wu,China CDC’s Chief Expert in Parasitic Disease Control显示文摘Weiping Wu is a leading expert in parasitic diseases and leads more than ten key projects that focus on important parasitic diseases including schistosomiasis,filariasis,leishmaniasis,and echinococcosis.Over his career,he’s achieved several milestone results including the spatial aggregation of the distribution of leishmaniasis cases and related livestock after 15 years of study in the desert area of Xinjiang Uyghur Autonomous Region,almost 40 publications in SCI journals as the first or corresponding author,and significant contributions to several key documents including the“Action plan for the control of echinococcosis in China”in 1995,“Diagnosis for echinococcosis,”and“Echinococcosis control,”all of which have helped standardize prevention and control practices for effective echinococcosis management. | Peter Hao Yu Chen Zhenjun Li Jingjing Xi Feng Tan | 2020 | China CDC weekly2020，2，33： | 0 |
| 14 | Linhong Wang,China CDC’s Chief Expert of Chronic and Non-Communicable Disease Control显示文摘Linhong Wang is the Chief Expert of Chronic and Non-Communicable Disease(NCD)Control of China CDC and is a professional with over 30 years of experience in clinical and preventive medical science.Her specialties and professions span multiple fields with extraordinary contributions to public health.Wang graduated from Beijing Medical University in 1983 with her first job out of university as an obstetrician and gynecologist in the Affiliated Hospital of the University. | Peter Hao Yu Chen Zhenjun Li Jingjing Xi Feng Tan | 2020 | China CDC weekly2020，2，35： | 0 |
| 15 | Surprisingly fast cooling in graphene-based van der Waals stacks显示文摘A thorough understanding of nanoscale heat flow inheterostructures is crucial for future multifunctional na-nodevices based on 2D materials. For example, the ther-mal exchanges based on hot-carrier cooling pathways andtime in graphene devices have been rigorously in-vestigated, and these studies provide guidance for thedevelopment of electronic and optoelectronic applications[1,2]. Furthermore, defect-assisted acoustic phononscattering [3], intrinsic optical phonon (OP) cooling [4],and interlayer Coulomb coupling [5] are the three pri-mary relaxation mechanisms in diffusive, suspended, anddecoupled multilayer graphene, respectively. However,perfect supported or encapsulated graphene, in whichelectrons are coupled to remote polar phonon modes, isdifferent from the other types of graphene mentionedabove, and it lacks sufficient experimental research. | Hailin Peng Zhenjun Tan | 2018 | Science China Materials2018，61，7： | 0 |
| 16 | Xi Jin,China CDC’s Chief Expert of Maternal and Child Health显示文摘Editorial Our new column Profiles is a new series that aims to introduce China CDC’s chief experts,major decisionmakers,and key contributors that ensure the high standard of operation of China CDC.These articles are meant to present high-achieving individuals of China CDC and will describe the background,achievements,and paths to success of the eponymous individuals. | Peter Hao Xi Jin Xiaoqi Wang Zhenjun Li Jingjing Xi Feng Tan | 2020 | China CDC weekly2020，2，28： | 0 |
| 17 | Huaqing Wang,China CDC’s Chief Expert in National Immunization Program显示文摘Huaqing Wang has had a long and distinguished career in developing and implementing immunization programs to protect China’s people.After graduating from Harbin Medical University in 1986 with a major in preventive medicine,Huaqing Wang was assigned to Heilongjiang Provincial CDC and has dedicated his career to infectious disease control and immunization. | Peter Hao Ying Zhang Zhenjun Li Jingjing Xi Feng Tan | 2020 | China CDC weekly2020，2，30： | 0 |
| 18 | Qiyong Liu,China CDC’s Chief Expert of Vector Control显示文摘Qiyong Liu is a leading expert and scientist for vector surveillance and control and leads national research on health and climate change in China.Qiyong Liu heads the World Health Organization(WHO)Collaborating Centre for Vector Surveillance and Management(WHOCCVSM)and has been awarded over 20 national and international prestigious grants including the following:National Basic Research Program of China(973 Program),the National Natural Science Foundation of China(NSFC),National Programs for Science and Technology Development,Australian Agency for International Development(AusAID),China Prosperity Strategic Programme Fund(SPF),and Wellcome Trust. | Peter Hao Yu Chen Zhenjun Li Jingjing Xi Feng Tan | 2020 | China CDC weekly2020，2，31： | 0 |
| 19 | Tao Li,China CDC’s Chief Expert in Occupational Health显示文摘If the national college entrance examination had not resumed or if the Chinese policies for talent turnover had not been established,Tao Li might have continued his grassroots occupational health work and might never have joined China CDC.Born in 1957,Tao Li had once worked at a county-level knitting factory in northeastern China for a year before China resumed the college entrance examination. | Peter Hao Ying Zhang Zhenjun Li Jingjing Xi Feng Tan | 2020 | China CDC weekly2020，2，32： | 0 |
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