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| 1 | Computer Simulation of Mechanical Properties of Nano-scale Cu/FeS Composite显示文摘The mechanical properties of nano-scale Cu/FeS composite were simulated by molecular dynamics (MD) simulation in this paper. Through the analysis on the stress-strain curves, the results of MD simulation were in good agreement with mechanisms of macroscopic deformation. When the size of particles was smaller than a certain value, the relationship between yield strength and size, which was different from the large size crystals abided by the contrary Hall-Petch relationship. Based on the discussion of nano-scale Cu/FeS composite, some interesting conclusions were obtained. For example, the 'S' type curves were discovered in stress-strain curves and the anisotropy of FeS was very evident when the exposures of reinforcing phase (FeS) were different and so on. The basic theories and calculations of the composite that contains nano-scale particles were discussed. At the same time, a new modeling building method of composites, which was close to actual experiences, were considered in this paper. | Zhenjun Hong Jingchao Chen Jing Feng Yeping Du Jie Yu Lijuan Zhang Shuzhen Wu Futai Xu | 2010 | Journal of Materials Science & Technology2010，26，4： | 2 |
| 2 | Effect of quenching temperature on structure and properties of centrifugal casting high speed steel roll显示文摘The critical points and time-temperature-transformation(TTT)curves of the isothermal transformation diagrams for a high-speed steel casting on a horizontal centrifugal casting machine had been determined experimentally in the study.The effects of quenching temperature on the microstructures and properties of centrifugal casting high speed steel(HSS)roll has been investigated using scanning electron microscopy(SEM), light optical microscopy(LOM)and X-ray diffraction(XRD)as well as using tensile,impact,and hardness tests. The results show that the HSS roll has excellent hardenability and its matrix structure can be transformed into the martensite after being quenched in the sodium silicate solution.The retained austenite in the quenching structure increases and the hardness decreases when the quenching temperature exceeds 1,040℃.The tensile strength and impact toughness of HSS roll increase once the quenching temperature is raised from 980℃to 1,040℃. However,the tensile strength and impact toughness have no significant change when the quenching temperature exceeds 1,040℃.The HSS roll quenched at 1,040℃exhibits excellent comprehensive mechanical properties. | Fu Hanguang Cheng Xiaole Du Zhongze Lei Yingping Feng Zhenjun | 2009 | China Foundry2009，6，1： | 2 |
| 3 | Mechanical properties and microcosmic mechanism of cement modified asphalt emulsion concrete显示文摘 | DU Shaowen WANG Zhenjun | 2009 | Journal of Tongji University:Natural Science2009，37，8： | 1 |
| 4 | LncRNA-Airn alleviates acute liver injury by inhibiting hepatocyte apoptosis via the NF-κB signaling pathway显示文摘Acute liver injury is a common and serious syndrome caused by multiple factors and unclear pathogenesis.If the injury persists,liver injury can lead to cirrhosis and liver failure and ultimately results in the development of liver cancer.Emerging evidence has indicated that long noncoding RNAs(lncRNAs)play an important role in the development of liver injury.However,the role of antisense Igf2r RNA(Airn)in acute liver injury and its underlying mechanism remain largely unclear.In this study,we show that Airn is upregulated in liver tissue and primary hepatocytes from an acute liver injury mouse model.Consistently,Airn is also overexpressed in serum samples of patients with acute-on-chronic liver failure and is negatively correlated with the Model for End-Stage Liver Disease(MELD)score.Moreover,gene knockout and rescue assays reveal that Airn alleviates CCl_(4)-induced liver injury by inhibiting hepatocyte apoptosis and oxidative stress in vivo.Further investigation reveals that Airn decreases H_(2)O_(2)-induced hepatocyte apoptosis in vitro.Mechanistically,we reveal that Airn represses CCl_(4)-and H_(2)O_(2)-induced enhancement of phosphorylation of p65 and IκBα,suggesting that Airn inhibits hepatocyte apoptosis by inactivating the NF-κB pathway.In conclusion,our results demonstrate that Airn can alleviate acute liver injury by inhibiting hepatocyte apoptosis via inactivating the NF-κB signaling pathway,and Airn could be a potential biomarker for acute liver injury. | Shuai Shao Yu Zhang Feng Zhou Xiaoxiang Meng Zhenjun Yu Guantong Li Lina Zheng Kun Zhang Yuhan Li Beichen Guo Qi Liu Mengxia Zhang Xiaoxiao Du Wei Hong Tao Han | 2022 | Acta Biochimica et Biophysica Sinica2022，54，11： | 1 |
| 5 | DGConv: A Novel Convolutional Neural Network Approach for Weld Seam Depth Image Detection显示文摘We propose a novel image segmentation algorithm to tackle the challenge of limited recognition and segmentation performance in identifying welding seam images during robotic intelligent operations.Initially,to enhance the capability of deep neural networks in extracting geometric attributes from depth images,we developed a novel deep geometric convolution operator(DGConv).DGConv is utilized to construct a deep local geometric feature extraction module,facilitating a more comprehensive exploration of the intrinsic geometric information within depth images.Secondly,we integrate the newly proposed deep geometric feature module with the Fully Convolutional Network(FCN8)to establish a high-performance deep neural network algorithm tailored for depth image segmentation.Concurrently,we enhance the FCN8 detection head by separating the segmentation and classification processes.This enhancement significantly boosts the network’s overall detection capability.Thirdly,for a comprehensive assessment of our proposed algorithm and its applicability in real-world industrial settings,we curated a line-scan image dataset featuring weld seams.This dataset,named the Standardized Linear Depth Profile(SLDP)dataset,was collected from actual industrial sites where autonomous robots are in operation.Ultimately,we conducted experiments utilizing the SLDP dataset,achieving an average accuracy of 92.7%.Our proposed approach exhibited a remarkable performance improvement over the prior method on the identical dataset.Moreover,we have successfully deployed the proposed algorithm in genuine industrial environments,fulfilling the prerequisites of unmanned robot operations. | Pengchao Li Fang Xu Jintao Wang Haibing Guo Mingmin Liu Zhenjun Du | 2024 | Computers, Materials & Continua2024，78，2： | 0 |
| 6 | Synthesis and biological evaluation of peptide-siRNA conjugates with phosphodiester unit as linker显示文摘In this paper,a series of peptide-siRNA conjugates with phosphodiester unit as the linker targeting to Cdc2 gene were synthesized by solid phase stepwise strategy.The conjugation of peptides at either 3’-terminus of siCdc2 bring no change to the classical A-form of RNA duplex,but slightly compromise the thermodynamic stability.Peptide conjugation at the 3’-terminus of sense strand could improve the serum stability obviously,however,the opposite peptide conjugation at the 3’-terminus of antisense strand shows no such influence.According to the results of artificial silencing activity assay system,peptide conjugation at 3’-terminus of antisense strand slightly weakens the silencing activity of siCdc2.But sense strand peptide conjugation exhibits similar silencing activity as native siCdc2,meanwhile,it could mitigate the unwanted off-target effect of sense strand targeting to its own mRNA. | WANG XiaoFeng HUANG Ye LIU Yang CHEN Yue JIN HongWei ZHENG Yi DU Quan YANG ZhenJun ZHANG LiHe | 2013 | Science China Chemistry2013，56，11： | 0 |
| 7 | Self-accommodated defect structures modifying the growth of Laves phase显示文摘Laves phases,with the topologically close-packed structure and a chemical formula of Ab_(2),constitute the largest single class of intermetallics.Planar defects in Laves phases are widely investigated,especially for stacking behavior transformations through synchroshear.Here,we report the coexistence of C14,C36 and C15 structures in MgZn_2 precipitates by using atomic resolution scanning transmission electron microscopy,verifying the previously predicted Laves phase transformation sequence of C14→C36→C15 also applies to MgZn_2.One type of stacking fault couple in precipitates has been found to alone reduce the lattice mismatch with matrix,while some other stacking fault couples need to self-accommodate with irregular planar defects(rhombic units and flattened hexagonal units),or with five-fold symmetry structures to relieve the strain concentration.Precipitates thus grow towards an equiaxed or even round morphology,rather than the plate morphology as conventionally believed.Molecular dynamics calculations are performed to support our analysis.These findings reveal the principles governing the concurrent occurrence of various defects in laves structures,acting as an update of the widely accepted perception of random occurrence of defects during crystal growth. | Tong Yang Yi Kong Jiangbo Lu Zhenjun Zhang Mingjun Yang Ning Yan Kai Li Yong Du | 2021 | Journal of Materials Science & Technology2021，，3： | 0 |
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