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| 1 | Relationship Between Grain Yield and Yield Components in Super Hybrid Rice显示文摘Chinese super hybrid rice breeding project has developed many new varieties with great yield potential. It is controversial which yield component should be emphasized in super hybrid rice production. The present study was conducted to compare super hybrid rice with common hybrid and super inbred rice and analyze contributions of yield components to grain yield of super hybrid rice under experimental conditions, and evaluate relationships between grain yield and yield components of super hybrid rice in farmer’s paddy fields. Field experiments were done in Changsha, Guidong, and Nanxian, Hunan Province, China, from 2007 to 2009. Eight super hybrid varieties, one common hybrid variety, and one super inbred variety were grown in each location and year. Rice production investigation was undertaken in high-yielding (Guidong), moderate-yielding (Nanxian), and low-yielding (Ningxiang) regions of Hunan Province, China, in 2009. Grain yield and yield components were measured in both the field experiments and rice production investigation. Super hybrid rice varieties outyielded common hybrid and super inbred varieties across three locations and years. Yield potential has been increased by 11.4% in super hybrid rice varieties compared with common and super inbred varieties. The higher yield of super hybrid varieties was attributed to improvement in panicle size. Panicles per m2 had the highest positive contribution to grain yield with the exception under yield level of 10.0 to 12.0 t ha-1, and was positively related to grain yield in farmer’s field at all of the high-, moderate-, and low-yielding regions. Our study suggests that panicle per m2 ought to be emphasized in super hybrid rice production. | HUANG Min ZOU Ying-bin JIANG Peng XIA Bing Md Ibrahim AO He-jun | 2011 | Agricultural Sciences in China2011，10，10： | 41 |
| 2 | Endoscopic submucosal dissection vs endoscopic mucosal resection for superficial esophageal cancer显示文摘AIM:To investigate the effectiveness of endoscopic submucosal dissection(ESD)and endoscopic mucosal resection(EMR)in treating superficial esophageal cancer(SEC).METHODS:Studies investigating the safety and efficacy of ESD and EMR for SEC were searched from the databases of Pubmed,Web of Science,EMBASE and the Cochrane Library.Primary end points included the en bloc resection rate and the curative resection rate.Secondary end points included operative time,rates of perforation,postoperative esophageal stricture,bleeding and local recurrence.The random-effect model and the fixed-effect model were used for statistical analysis.RESULTS:Eight studies were identified and included in the meta-analysis.As shown by the pooled analysis,ESD had significantly higher en bloc and curative resection rates than EMR.Local recurrence rate in the ESD group was remarkably lower than that in the EMR group.However,operative time and perforation rate for ESD were significantly higher than those for EMR.As for the rate of postoperative esophageal stricture and procedure-related bleeding,no significant difference was found between the two techniques.CONCLUSION:ESD seems superior to EMR in the treatment of SEC as evidenced by significantly higher en bloc and curative resection rates and by obviously lower local recurrence rate. | Hui-Min Guo Xiao-Qi Zhang Min Chen Shu-Ling Huang Xiao-Ping Zou | 2014 | World Journal of Gastroenterology2014，20，18： | 30 |
| 3 | Abnormal expression of HSP gp96 associated with HBV replication in human hepatocellular carcinoma显示文摘BACKGROUND: Heat shock protein (HSP) gp96 is a member of the HSP90 family and presumably overexpresses as a result of stimulation by mutated or abnormal proteins. Its abnormal expression correlates with carcinogenesis, progression and prognosis of hepatocellular carcinoma (HCC). In this study, we investigated the pathological characteristics of liver gp96 expression and its relationship with hepatitis B virus (HBV) replication in HCC patients. METHODS: Tumor specimens were prospectively collected from 30 HCC patients undergoing liver resection. Total RNAs were extracted from HCC or their noncancerous tissues. The distribution of gp96 expression in hepatocytes was investigated by streptavidin peroxidase (S-P) immunohistochemistry and tissue HBV-DNA was detected by the in situ molecular hybridization technique. The association of gp96 expression with HBV replication, and the histopathological characteristics of HCC were analyzed. RESULTS: The gp96 was strongly expressed in HCC (73.3%, 22 of 30) and weakly (46.7%, 14 of 30) in non-cancerous tissues. The gp96 expression in HCC tissues was correlated with degree of tumor differentiation and tumor size, but not with tumor number (P>0.05). Immunohistochemical analysis showed that 17 of 19 HCC patients with HBVDNA -positive were strongly expressed for gp96, whereas only 5 of 11 patients with HBV-DNA-negative were positive for gp96. A significant difference was found between the two groups (89.5% vs. 45.5%, P<0.05). CONCLUSIONS: The abnormal expressions of HSP gp96 in HCC tissues are associated with HBV replication. This finding indicates that HBV infection plays an important role in the development of HCC. | Deng-Fu Yao,Xin-Hua Wu,Xiao-Qin Su,Min Yao, Wei Wu, Li-Wei Qiu, Li Zou and Xian-Yong Meng The Institute of Clinical Medicine, Nantong University, and Department of Gastroenterology,Affiliated Hospital of Nantong University, Nantong 226001, China and Nanjing Medical University, Nanjing 210009, China | 2006 | Hepatobiliary & Pancreatic Diseases International2006，5，3： | 14 |
| 4 | Involvement of interstitial cells of Cajal in experimental severe acute pancreatitis in rats显示文摘AIM:To observe the changes in interstitial cells of Cajal(ICC) in rats with experimental severe acute pancreatitis(SAP).METHODS:A total of twenty-four SD rats were randomly divided into two groups(n = 12),namely the sham(S) group and the SAP group;the SAP rat model was established by retrograde injection of 5% sodium taurocholate(1.0 mL/kg) into the pancreatic duct.Twenty-four hours later intestinal motility was assessed by testing small intestinal propulsion rate,and then the rats were sacrificed.The pancreas and jejunum were resected and underwent routine pathologic examination.Immunohistochemical staining was used to detect c-kit-positive cells in the jejunum.Expression of c-kit mRNA was detected by real-time polymerase chain reaction,and the expression of c-kit protein was evaluated by Western blotting.Ultrastructure of ICC was evaluated by transmission electron microscopy.RESULTS:There was bleeding,necrosis and a largeamount of inflammatory cell infiltration in pancreatic tissue in the SAP group,while in jejunal tissue we observed a markedly denuded mucosal layer,loss of villous tissue and a slightly dilated muscular layer.The small intestinal propulsion rate was 68.66% ± 2.66% in the S group and 41.55% ± 3.85% in the SAP group.Compared with the S group,the rate of the SAP group decreased sharply.The density of c-kit-positive cells in the SAP group was significantly lower than in the S group;the respective mean densities were 88.47 ± 10.49 in the S group and 56.11 ± 7.09 in the SAP group.The levels of c-kit protein and mRNA were 0.36 ± 0.04 and 1.29 ± 0.91 in the SAP group,respectively,which were significantly lower than those in the S group(0.53 ± 0.06,0.64 ± 0.33,respectively).In the SAP group,ICC profiles showed the same change tendency,such as vacuolation of mitochondria,irregular vacuoles and loosened desmosome-like junctions.CONCLUSION:Decreased c-kit-positive cells and ultrastructural changes in ICC resulting from blockade of the c-kit signaling pathway are involved in the intestinal dysmotility associated with SAP. | Liang-Liang Shi Ming-Dong Liu Min Chen Xiao-Ping Zou | 2013 | World Journal of Gastroenterology2013，19，14： | 13 |
| 5 | Artesunate attenuates LPS-induced osteoclastogenesis by suppressing TLR4/TRAF6 and PLCγ1-Ca^(2+)-NFATc1 signaling pathway显示文摘In chronic infectious diseases caused by gram-negative bacteria,such as osteomyelitis,septic arthritis,and periodontitis,osteoclastic activity is enhanced with elevated inflammation,which disturbs the bone homeostasis and results in osteolysis.Lipopolysaccharide(LPS),as a bacteria product,plays an important role in this process.Recent evidence shows that an antimalarial drug artesunate attenuates LPS-induced osteolysis independent of RANKL.In this study we evaluated the effects of artesunate on LPS-induced osteoclastogenesis in vitro and femur osteolysis in vivo,and explored the mechanisms underlying the effects of artesunate on LPS-induced osteoclast differentiation independent of RANKL.In preosteoclastic RAW264.7 cells,we found that artesunate(1.56?12.5μM)dose dependently inhibited LPS-induced osteoclast formation accompanied by suppressing LPS-stimulated osteoclast-related gene expression(Fra-2,TRAP,Cathepsin K,β3-integrin,DC-STAMP,and Atp6v0d2).We showed that artesunate(3.125?12.5μM)inhibited LPS-stimulated nuclear factor of activated T cells c1(NFATc1)but not NF-κB transcriptional activity;artesunate(6.25,12.5μM)significantly inhibited LPS-stimulated NFATc1 protein expression.Furthermore,artesunate treatment markedly suppressed LPS-induced Ca2+influx,and decreased the expression of PP2B-Aα(calcineurin)and pPLCγ1 in the cells.In addition,artesunate treatment significantly decreased the expression of upstream signals TLR4 and TRAF6 during LPS-induced osteoclastogenesis.Administration of artesunate(10 mg/kg,ip)for 8 days effectively inhibited serum TNF-αlevels and ameliorated LPS(5 mg/kg,ip)-induced inflammatory bone loss in vivo.Taken together,artesunate attenuates LPS-induced inflammatory osteoclastogenesis by inhibiting the expression of TLR4/TRAF6 and the downstream PLCγ1-Ca^2+-NFATc1 signaling pathway.Artesunate is a valuable choice to treat bone loss induced by gram-negative bacteria infection or inflammation in RANKL-independent pathway. | Xiang-zhou Zeng Yue-yang Zhang Qin Yang Song Wang Bin-hua Zou Yan-hui Tan Min Zou Shu-wen Liu Xiao-juan Li | 2020 | Acta Pharmacologica Sinica2020，41，2： | 12 |
| 6 | PPARy agonists inhibit TGF-β-PKA signaling in glomeru Iosclerosis显示文摘 | Rong ZOU Gang XU Xiao-cheng LIU Min HAN Jing-jing JIANG Qian HUANG Yong HE Ying YAO | 2010 | Acta Pharmacologica Sinica2010，31，1： | 12 |
| 7 | Insight-HXMT observations of the first binary neutron star merger GW170817显示文摘Finding the electromagnetic(EM) counterpart of binary compact star merger, especially the binary neutron star(BNS) merger,is critically important for gravitational wave(GW) astronomy, cosmology and fundamental physics. On Aug. 17, 2017,Advanced LIGO and Fermi/GBM independently triggered the first BNS merger, GW170817, and its high energy EM counterpart,GRB 170817 A, respectively, resulting in a global observation campaign covering gamma-ray, X-ray, UV, optical, IR, radio as well as neutrinos. The High Energy X-ray telescope(HE) onboard Insight-HXMT(Hard X-ray Modulation Telescope) is the unique high-energy gamma-ray telescope that monitored the entire GW localization area and especially the optical counterpart(SSS17 a/AT2017 gfo) with very large collection area(~1000 cm^2) and microsecond time resolution in 0.2-5 MeV. In addition,Insight-HXMT quickly implemented a Target of Opportunity(ToO) observation to scan the GW localization area for potential X-ray emission from the GW source. Although Insight-HXMT did not detect any significant high energy(0.2-5 MeV) radiation from GW170817, its observation helped to confirm the unexpected weak and soft nature of GRB 170817 A. Meanwhile,Insight-HXMT/HE provides one of the most stringent constraints(~10^(-7) to 10^(-6) erg/cm^2/s) for both GRB170817 A and any other possible precursor or extended emissions in 0.2-5 MeV, which help us to better understand the properties of EM radiation from this BNS merger. Therefore the observation of Insight-HXMT constitutes an important chapter in the full context of multi-wavelength and multi-messenger observation of this historical GW event. | TiPei Li ShaoLin Xiong ShuangNan Zhang FangJun Lu LiMing Song XueLei Cao Zhi Chang Gang Chen Li Chen TianXiang Chen Yong Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong YuanYuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao CongZhan Liu GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge OU JinLu Qu Na Sai Liang Sun Yin Tan Lian Tao WenHui Tao YouLi Tuo GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BoBing WU Mei Wu GuangCheng Xiao He Xu YuPeng Xu LinLi Yan JiaWei Yang Sheng Yang YanJi Yang AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang Shu Zhang Tong Zhang Wei Zhang WanChang Zhang WenZhao Zhang Yi Zhang Yue Zhang YiFei Zhang YongJie Zhang Zhao Zhang ZiLiang Zhang HaiSheng Zhao JianLing Zhao XiaoFan Zhao ShiJie Zheng Yue Zhu YuXuan Zhu ChangLin Zou | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，3： | 12 |
| 8 | Chang'E-1 Lunar Mission:An Overview and Primary Science Results显示文摘Chang'E-1 is the first lunar mission in China,which was successfully launched on Oct.24th,2007.It was guided to crash on the Moon on March 1,2009,at 52.36°E,1.50°S,in the north of Mare Fecunditatis.The total mission lasted 495 days,exceeding the designed life-span about four months.1.37Terabytes raw data was received from Chang'E-1.It was then processed into 4Terabytes science data at different levels.A series of science results have been achieved by analyzing and applicating these data,especially 'global image of the Moon of China's first lunar exploration mission'.Four scientific goals of Chang'E-1 have been achieved.It provides abundant materials for the research of lunar sciences and cosmochemistry.Meanwhile these results will serve for China's future lunar missions. | Ouyang Ziyuan Li Chunlai Lu Chang Liu Jianzhong Zou Yongliao Zhang Hongbo Jianjun Zuo Wei Su Yah Wen Weibin Bian Wei Zhao Baochang Wang Jianyu Yang Jianfeng Chang Jin Wang Huanyu Zhang Xiaohui Wang Shijin Wang Min Ren Xin Mu Lingli Kong Deqing Wang Xiaoqian Wang Fang Geng Liang Zhang Zhoubin Zheng Lei Zhu Xinying Zheng Yongchun Li Junduo Zou Xiaoduan Xu Chun Shi Shuobiao Gao Yifei Gao Guannan | 2010 | 空间科学学报2010，30，5： | 11 |
| 9 | Yield potential and stability in super hybrid rice and its production strategies显示文摘China's Super Hybrid Rice Breeding Program has made significant progress over the past two decades. In this paper, we reviewed our studies on the yield potential and stability in super hybrid rice and discussed the strategies for super hybrid rice production. The results of our studies show that rice yield potential has been increased by 12% in super hybrid cultivars as compared with ordinary hybrid and inbred cultivars. The higher grain yields in super hybrid rice cultivars are attributed to larger panicle size coupled with higher biomass production or higher harvest index. However, grain yields in super hybrid rice cultivars vary widely among locations depending on soil and climatic factors. Therefore, it is important to tailor target yield to local conditions in super hybrid rice production. The target yield for super hybrid rice production can be determined by the average yield method or the regression model method. Improving soil quality is critical to achieving the target yield in super hybrid rice production. Favorable crop rotations such as rice-oilseed rape and novel soil management practices, such as biochar addition, are effective approaches to improve soil quality. It is needed to develop simplified cultivation technologies for super hybrid rice to meet the changes in socioeconomic environments during the period of transition. There are such technologies as no-tillage direct seeding and mechanized transplanting at high hill density with single seedling per hill. | HUANG Min TANG Qi-yuan AO He-jun ZOU Ying-bin | 2017 | Journal of Integrative Agriculture2017，16，5： | 11 |
| 10 | Risk factor analysis of post-ERCP cholangitis: A single-center experience显示文摘Background: Endoscopic retrograde cholangiopancreatography(ERCP) may have complications. Our study aimed to investigate the risk factors and prevention of post-ERCP cholangitis.Methods: We retrospectively analyzed 4234 cases undergone ERCP in the Affiliated Drum Tower Hospital of Nanjing University Medical School from January 2008 to December 2013. Patient-related factors and procedure-related factors were analyzed to find the risk factors of post-ERCP cholangitis. The time point of post-ERCP cholangitis was also analyzed. Univariate and multivariate analyses were performed to define the independent risk factors of post-ERCP cholangitis.Results: The success rate of ERCP was 96.8%(4099/4234). The overall complication rate was 9.4%(399/4234). Post-ERCP cholangitis occurred in 102 cases(2.4%, 102/4234). The most dangerous time of post-ERCP cholangitis was from 24 h–48 h after ERCP(45.1%, 46/102). Univariate analysis revealed that age, hypertension, diabetes, previous ERCP history, biliary stent insertion, pancreatography, endoscopic sphincterotomy, balloon dilation and hilar obstruction were risk factors of post-ERCP cholangitis(P < 0.05). Multivariate analysis indicated that age, previous ERCP history and hilar obstruction were independent risk factors(P < 0.05). While endoscopic stone extraction was the potential protective factor.Conclusions: Many risk factors are involved in post-ERCP cholangitis. Among them, old age, previous ERCP history and hilar obstruction were independently related to this post-ERCP complication. | Min Chen Lei Wang Yun Wang Wei Wei Yu-Ling Yao Ting-Sheng Ling Yong-Hua Shen Xiao-Ping Zou | 2018 | Hepatobiliary & Pancreatic Diseases International2018，17，1： | 11 |
| 11 | Superhydrophobic Surfaces Produced by Applying a Self- Assembled Monolayer to Silicon Micro/Nano-Textured Surfaces显示文摘A novel way of producing superhydrophobic surfaces by applying a self-assembled monolayer(SAM)to silicon micro/nano-textured surfaces is presented in this paper.The micro/nano-textured surfaces on silicon substrates were generated by the aluminum-induced crystallization(AIC)of amorphous silicon(a-Si)technique.Octadecyltrichlorosilane(OTS)SAMs were then applied to the textured surfaces by dip coating.The topography and wetting properties of the resulting surfaces were characterized using scanning electron microscopy(SEM)and a video-based contact angle measurement system.The results show that by introducing OTS SAMs on the silicon micro/nano-textured surfaces,superhydrophobic surfaces with water contact angles(WCAs)of 155°were obtained,as compared to the WCAs of OTS-modified smooth silicon surfaces of about 112°.Surface topography was found to directly influence the WCA as predicted by the Cassie-Baxter model. | Yong Song Rahul Premachandran Nair Min Zou Yongqiang Wang | 2009 | Nano Research2009，2，2： | 11 |
| 12 | Heterogeneous oxidation of cyclohexanone catalyzed by TS-1:Combined experimental and DFT studies显示文摘 | Changjiu Xia Long Ju Yi Zhao Hongyi Xu Bin Zhu Feifei Gao Min Lin Zhenyu Dai Xiaodong Zou Xingtian Shu | 2015 | 催化学报2015，36，6： | 11 |
| 13 | Micromanufacturing technologies of compact heat exchangers for hypersonic precooled airbreathing propulsion: A review显示文摘The Hypersonic Precooled Combined Cycle Engine(HPCCE), which introduces precooler into traditional hypersonic engine, is regarded as the most promising propulsion system for realizing a single-stage-to-orbit vehicle. The unique demands lead to the application of the compact heat exchangers, which can realize high thrust-to-weight ratio, sufficient specific impulse and high compression ratio. However, it is challenging to accurately manufacture the compact heat exchanger due to its extremely high heat dissipation capacity, remarkable compactness, superior adaptability and harsh operating condition. This review summarizes the precooling schemes of combined cycle propulsions and describes the demands and key issues in the fabrication of a compact heat exchanger for HPCCE. The investigation focuses on the application of various micromanufacturing methods of heat exchangers constructed from tubes of less than 1 mm in diameter and microchannels of less than 200 micrometers. Various micromanufacturing processes, which include microforming, micromachining, stereolithography, chemical etching, 3 D printing, joining and other advanced microfabricating processes, were reviewed. In addition, the technologies are compared in terms of dimensional tolerance, material compatibility, and process applicability. Furthermore, the boundaries of the micromanufacturing constraints are specified as references for the design of compact heat exchangers. Ultimately, the technological difficulties and development trends are discussed for the fabrication of compact heat exchangers for HPCCE. | Bao MENG Min WAN Rui ZHAO Zhengping ZOU Huoxing LIU | 2021 | Chinese Journal of Aeronautics2021，34，2： | 10 |
| 14 | Comparisons of Yield and Growth Behaviors of Hybrid Rice Under Different Nitrogen Management Methods in Tropical and Subtropical Environments显示文摘To compare the grain yield and growth behaviors of hybrid rice, field experiments were conducted in a subtropical environment in Changsha, Hunan Province, China, and in two tropical environments in Gazipur and Habiganj in Bangladesh during 2009 to 2011. Three hybrid rice cultivars were grown under three nitrogen (N) management treatments in each experiment. The results showed that grain yield was significantly affected by locations, N treatments and their interaction but not by cultivars. Changsha produced 8-58% higher grain yields than Bangladesh locations. Sink size (spikelet number per unit land area) was responsible for these yield differences. Larger panicle size (spikelet number per panicle) contributed to greater sink size in Changsha. Aboveground total biomass was greater in Changsha than in Bangladesh locations, whereas harvest index was higher in Bangladesh locations than in Changsha. Crop growth rate (CGR) was greater at Changsha than Bangladesh locations during vegetative phase, while the difference was relatively small and not consistent during the later growth phases. Higher leaf area index and leaf area duration were partly responsible for the greater CGR in Changsha. Real-time N management (RTNM) produced lower grain yields than fixed-time N management in more than half of the experiments. Our study suggested that further improvement in rice yield in the tropical environments similar to those of Bangladesh will depend mainly on the ability to increase panicle size as well as CGR during vegetative phase, and the chlorophyll meter threshold value used in RTNM needs to be modified according to environmental conditions and cultivar characteristics to achieve a desirable grain yield. | Ibrahim Md PENG Shao-bing TANG Qi-yuan HUANG Min JIANG Peng ZOU Ying-bin | 2013 | Journal of Integrative Agriculture2013，12，4： | 10 |
| 15 | Effects of single basal application of coated compound fertilizer on yield and nitrogen use efficiency in double-cropped rice显示文摘Fertilizer plays an important role in increasing rice yield. More than half of all fertilizer applied to the field is not taken up, resulting in environmental damage and substantial economic losses. To address these concerns, a low-cost, coated compound fertilizer named 'Xiang Nong Da'(XND), requiring only a single basal application, was studied. A two-year field experiment was conducted to test the effects of XND application on rice yield and nitrogen fertilizer use efficiency. An ordinary uncoated compound fertilizer(UNCF), with 20% more nutrients and split application was selected as the control. The yield of XND-treated rice was only 3.1% lower than that of the control, an insignificant difference. There were no significant differences between N use efficiency indices of the two fertilizer treatments except for N partial factor productivity(PFP_N). PFP_Nof XND treatment was 19.7%–23.2% higher than the control, a significant difference. This result indicates that a 20% decrease in N application rate is possible with XND without yield reduction and with savings in both labor and time. | Jiana Chen Fangbo Cao Hairong Xiong Min Huang Yingbin Zou Yuanfu Xiong | 2017 | The Crop Journal2017，5，3： | 9 |
| 16 | Dynamic alteration of telomerase expression and its diagnostic significance in liver or peripheral blood for hepatocellular carcinoma显示文摘瞄准:在肝纸巾或外部血在肝细胞癌(HCC ) 和它的诊断含意的开发期间调查 telomerase 表示的动态改变为 HCC 的单音的原子房间。方法:肝 telomerase 的动态表情在 hepatocytes 的恶意的转变期间被观察在(SD ) Sprague-Dawly,老鼠用 0.05% 2-fluoenyacetamide (2-FAA ) 喂了。全部的 RNA 和 telomerase 从老鼠或人的肝纸巾被提取。在肝并且在传播的血的 telomerase 活动被 telomeric 重复扩大 protocol-enzyme-linked 免疫吸着剂试金(TRAP-ELISA ) 检测,并且它的诊断价值与良性或恶意的肝疾病在病人被调查。结果:肝细胞瘤模型在 HCC 开发期间显示了肝的 telomerase 的动态表示。telomerase 活动与肝总数 RNA 层次一致(r = 0.83, P<0.01 ) 在 hepatocytes 的退化,初癌状态,和癌化的阶段。在 HCC 病人,在 HCC 纸巾的 telomerase 层次比在他们的邻近的非癌的纸巾,而是肝全部的 RNA 铺平显著地高比在后者在前者是更低的。尽管 HCC 病人的传播 telomerase 反常地与长期的肝疾病在病人之中被表示,因为发生在正常控制是15.7%, telomerase 活动是为 HCC 诊断的一个非特定的标记,25%在长期的肝炎,45.9%在肝肝硬化,并且85.2%在 HCC ,分别地吸收度什么时候 telomerase 活动珍视,是超过 0.2 。如果价值是超过 0.6,发生在 HCC 组是 60% 并且 0% 在除了在有肝的二种情况中的其它(P<0.01 ) 的任何东西肝硬化。然而,有浆液 alpha-fetoprotein 水平的传播 telomerase 的联合能增加积极的率和精确性(92.6% , 135 中的 125 个) HCC 诊断。结论:过去 telomerase 的表示在肝纸巾与 HCC 开发,和它的反常被联系或在外设,血能是为 HCC 的诊断和预后的一个有用标记。 | Deng-Fu Yao Wei Wu Min Yao Li-Wei Qiu Xin-Hua Wu Xiao-Qin Su Li Zou Deng-Bing Yao Xian-Yong Meng | 2006 | World Journal of Gastroenterology2006，12，31： | 9 |
| 17 | Continuous applications of biochar to rice: Effects on grain yield and yield attributes显示文摘Biochar is considered as a beneficial soil amendment for crop production. However, limited information is available on the effects of continuous applications of biochar on rice. In this study, a fixed field experiment was conducted in the early and late rice-growing seasons from 2015 to 2017. Grain yield and yield attributes with a widely-grown rice cultivar Zhongzao 39 were compared, with and without applications of biochar in each season. The results showed that grain yield initially decreased with biochar applications in the first three seasons due to decreases in grain weight and harvest index. Although there were further relative decreases in grain weight and harvest index for rice that was supplied with biochar in the fourth to sixth seasons, grain yield was increased(by 4–10%) because of increases in sink size(spikelets per m2) and total biomass. The increased sink size in rice whose soil had been supplied with biochar in the fourth to sixth seasons was achieved by increasing panicle size(spikelets per panicle) or number of panicles, or both. Our study suggests that the positive effects of biochar application on rice yield and yield attributes depend on the duration of biochar application. Further investigations are needed to determine what are the soil and physiological processes for producing yield responses associated with ongoing applications of biochar. Also, it should be evaluated the performance of biochar application combined with other management practices, especially those can increase the grain weight and harvest index in rice production. | HUANG Min FAN Long JIANG Li-geng YANG Shu-ying ZOU Ying-bin Norman Uphoff | 2019 | Journal of Integrative Agriculture2019，18，3： | 9 |
| 18 | Standardization of CPUE for Chilean Jack Mackerel (Trachurus murphyi) from Chinese Trawl Fleets in the High Seas of the Southeast Pacific Ocean显示文摘The generalized linear model(GLM) and generalized additive model(GAM) were applied to the standardization of catch per unit effort(CPUE) for Chilean jack mackerel from Chinese factory trawl fishing fleets in the Southeast Pacific Ocean from 2001 to 2010 by removing the operational,environmental,spatial and temporal impacts.A total of 9 factors were selected to build the GLM and GAM,i.e.,Year,Month,Vessel,La Ni a and El Ni o events(ELE),Latitude,Longitude,Sea surface temperature(SST),SST anomaly(SSTA),Nino3.4 index and an interaction term between Longitude and Latitude.The first 5 factors were significant components in the GLM,which in combination explained 27.34% of the total variance in nominal CPUE.In the stepwise GAM,all factors explained 30.78% of the total variance,with Month,Year and Vessel as the main factors influencing CPUE.The higher CPUE occurred during the period April to July at a SST range of 12-15℃ and a SSTA range of 0.2-1.0℃.The CPUE was significantly higher in normal years compared with that in La Ni a and El Ni o years.The abundance of Chilean jack mackerel declined during 2001 and 2010,with an increase in 2007.This work provided the relative abundance index of Chilean jack mackerel for stock assessment by standardizing catch and effort data of Chinese trawl fisheries and examined the influence of temporal,spatial,environmental and fisheries operational factors on Chilean jack mackerel CPUE. | LI Gang ZOU Xiaorong CHEN Xinjun ZHOU Yinqi ZHANG Min | 2013 | Journal of Ocean University of China2013，12，3： | 9 |
| 19 | Why high grain yield can be achieved in single seedling machine-transplanted hybrid rice under dense planting conditions?显示文摘This study was conducted to identify the factors associated with high grain yield in single seedling machine-transplanted hybrid rice under dense planting conditions. Field experiments were done in Yong'an Town, Hunan Province, China in 2015 and 2016. Two hybrid rice cultivars were grown under single seedling machine transplanting(SMT) and conventional machine transplanting(CMT) at a high planting density in each year. Grain yield and yield attributes were compared between SMT and CMT. Averaged across cultivars and years, grain yield was 12% higher under SMT than under CMT. Plant height, basal stem width, and shoot and root dry weights were higher in seedlings for SMT than those for CMT. SMT had less maximum tiller number per m^2 and consequently less panicle number per m^2 than did CMT. Branch number per panicle, especially the secondary branch number per panicle, and spikelet number per cm of panicle length were more under SMT than under CMT, which resulted in more spikelet number per panicle under SMT than under CMT. SMT had higher or equal spikelet filling percentage than did CMT. The difference in grain weight between SMT and CMT was relatively small and inconsistent cross years. SMT had higher or equal total biomass and harvest index than did CMT. Dry weight per stem under SMT was heavier than that under CMT. Larger leaf area per stem was partly responsible for the heavier dry weight per stem under SMT than under CMT. Our study suggests that improvement in seedling quality, panicle size, and dry weight per stem are critical to the high grain yield in single seedling machine-transplanted hybrid rice under dense planting conditions. | HUANG Min SHAN Shuang-lü XIE Xiao-bing CAO Fang-bo ZOU Ying-bin | 2018 | Journal of Integrative Agriculture2018，17，6： | 8 |
| 20 | Comparative studies on epithelial lesions at gastric cardia and pyloric antrum in subjects from a high incidence area for esophageal cancer in Henan,China显示文摘ComparativestudiesonepitheliallesionsatgastriccardiaandpyloricantruminsubjectsfromahighincidenceareaforesophagealcancerinHena... | GAO ShanShan1, ZHOU Qi1, LI YongXin1, BAI YongMin1, ZHENG ZuoYu1, ZOU JianXiang1, LIU Gang1, FAN ZongMin1, QI YiJun1, ZHAO Xin1 and WANG LiDong1,2Keywords esophageal neoplasms stomach neoplasms gastric ca | 1998 | World Journal of Gastroenterology1998，4，4： | 8 |
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