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| 1 | The mixing of multi-source fluids in the Wusihe Zn–Pb ore deposit in Sichuan Province, Southwestern China显示文摘The Sichuan-Yunnan-Guizhou(SYG)metallogenic province of southwest China is one of the most important Zn-Pb ore zones in China,with^200 Mt ZnPb ores at mean grades of 10 wt.%Zn and 5 wt.%Pb.The source and mechanism of the regional Zn-Pb mineralization remain controversial despite many investigations that have been conducted.The Wusihe Zn-Pb deposit is a representative large-scale Zn-Pb deposit in the northern SYG,which mainly occurs in the Dengying Formation and yields Zn-Pb resources of^3.7 Mt.In this paper,Zn and S isotopes,and Fe and Cd contents of sphalerite from the Wusihe deposit were investigated in an attempt to constrain the controls on Zn and S isotopic variations,the potential sources of ore-forming components,and the possible mineralization mechanisms.Both theδ66Zn andδ34S values in sphalerite from the Wusihe deposit increase systematically from the bottom to the top of the strata-bound orebodies.Such spatial evolution inδ66Zn andδ34S values of sphalerite can be attributed to isotopic Rayleigh fractionation during sphalerite precipitation with temperature variations.The strong correlations between the Zn-S isotopic compositions and Fe-Cd concentrations in sphalerite suggest that their variations were dominated by a similar mechanism.However,the Rayleigh fractionation mechanism cannot explain the spatial variations of Fe and Cd concentrations of sphalerite in this deposit.It is noted that the bottom and top sphalerites from the strata-bound orebodies document contrasting Zn and S isotopic compositions which correspond to the Zn and S isotopic characteristics of basement rocks and host rocks,respectively.Therefore,the mixing of two-source fluids with distinct Zn-S isotopic signatures was responsible for the spatial variations of Zn-S isotopic compositions of sphalerite from the Wusihe deposit.The fluids from basement rocks are characterized by relatively lighter Zn(~0.2‰)and S(~5‰)isotopic compositions while the fluids from host rocks are marked by relatively heavier Zn(~0.6‰)and S(~15‰)isotopic compositions. | Hongjie Zhang Haifeng Fan Chaoyi Xiao Hanjie Wen Lin Ye Zhilong Huang Jiaxi Zhou Qingjun Guo | 2019 | Acta Geochimica2019，38，5： | 6 |
| 2 | Migration capacity of human umbilical cord mesenchymal stem cells towards glioma in vivo显示文摘High-grade glioma is the most common malignant primary brain tumor in adults.The poor prognosis of glioma,combined with a resistance to currently available treatments,necessitates the development of more effective tumor-selective therapies.Stem cell-based therapies are emerging as novel cell-based delivery vehicle for therapeutic agents.In the present study,we successfully isolated human umbilical cord mesenchymal stem cells by explant culture.The human umbilical cord mesenchymal stem cells were adherent to plastic surfaces,expressed specific surface phenotypes of mesenchymal stem cells as demonstrated by flow cytometry,and possessed multi-differentiation potentials in permissive induction media in vitro.Furthermore,human umbilical cord mesenchymal stem cells demonstrated excellent glioma-specific targeting capacity in established rat glioma models after intratumoral injection or contralateral ventricular administration in vivo.The excellent glioma-specific targeting ability and extensive intratumoral distribution of human umbilical cord mesenchymal stem cells indicate that they may serve as a novel cellular vehicle for delivering therapeutic molecules in glioma therapy. | Cungang Fan Dongliang Wang Qingjun Zhang Jingru Zhou | 2013 | Neural Regeneration Research2013，8，22： | 5 |
| 3 | Methods for assessing the grooving corrosion of high-frequency electric resistance welded pipes显示文摘Grooving corrosion is a major form of corrosion and is prone to occur when high-frequency electric resistance welded (HFW) pipes are being used.Therefore,grooving corrosion is one of the performance indexes of HFW products.Grooving corrosion usually occurs along the welding fusion line,resulting in one or more corrosion grooves.The main factors affecting grooving corrosion include the contents of alloying elements and impurities (especially sulphur) in the steel,the microstructure of the welds and the steel substrate,welding parameters and the service environment as well.In this study,the existing methods for assessing grooving corrosion were systematically reviewed,improvements and new methods were proposed and developed to overcome the shortcomings of the existing methods,such as inaccuracy and excessive research time.By comparison with the existing methods,the operational procedures and the characteristics of the new methods are introduced,and issues regarding the behavior of grooving corrosion and their assessment methods,which both need further research,are discussed in this study. | WANG Wei QI Huibin LIU Changsheng ZHOU Qingjun QIAN Yuhai SHEN Jianlan | 2010 | Baosteel Technical Research2010，4，3： | 5 |
| 4 | The mechanism of nucleation of hydrogen blister in metals显示文摘The nucleating, growing and cracking of hydrogen blister have been investigated experimentally and theoretically. The results show that atomic hydrogen induces superabundant vacancies in metals. The superabundant vacancies and hydrogen aggregate into a hydrogen-vacancy cluster (microcavity). The hydrogen atoms in the microcavity become hydrogen molecules which can stabilize the cluster. And the hydrogen blister nucleates. With the entry of vacancies and hydrogen atoms, the blister nucleus grows and the pressure in the cavity increases. When the stress induced by hydrogen pressure on the blister is up to the cohesive strength, cracks will initiate from the wall of the blister. | REN XueChong ZHOU QingJun CHU WuYang LI JinXu SU YanJing QIAO LiJie | 2007 | Chinese Science Bulletin2007，52，14： | 4 |
| 5 | The effect of interbeds on distribution of i ncremental oil displaced by a polymer flood显示文摘This paper discusses the effect of influ encing factors on the distribution of incremental oil displaced by a polymer flood(extra-displaced oil) using numerical reservoir simulation.These factors include the location,area and permeability of a thin low-permeability interbed,and the perforation location relative to the interbed.Simulation results show the locations from where the incremental oil was displaced by the polymer solution.The interbed position from the oil formation top affects the location of extra-displaced oil.The interbed area has a slight influence on the whole shape of extra-displaced oil.Larger interbed area leads to higher partition extent of extra-displaced oil.Higher vertical permeability of interbeds contributes to worse partition extent of extra-displaced oil and the partition effect disappears if the ratio of vertical to horizontal permeability is more than 0.05.The perforation location relative to the interbed affects polymer displacement efficiency,and also has a significant effect on the distribution of extra-displaced oil in polymer flooding. | Hou Jian Du Qingjun Lu Teng Zhou Kang Wang Rongrong | 2011 | Petroleum Science2011，8，2： | 3 |
| 6 | Revisiting the role of delta-1-pyrroline-5-carboxylate synthetase in drought-tolerant crop breeding显示文摘The delta-1-pyrroline-5-carboxylate synthetase(P5CS)gene exercises a protective function in stressed plants.However,the relationship between proline accumulation caused by P5CS and abiotic stress tolerance in plants is not always clear,as P5CS overexpression has been reported to repress plant growth under normal conditions in several reports.We re-evaluated the role of P5CS in drought-tolerant rice breeding by expressing the AtP5CS1 and feedback-inhibition-removed AtP5CS1(AtP5CS1^(F128A))genes under the regulation of an ABA-inducible promoter to avoid the potential side effects of P5CS overexpression under normal conditions.ABA-inducible AtP5CS1 and AtP5CS1^(F128A) increased seedling growth in a nutrient solution(under osmotic stress)and grain yield in pot plants.However,the evidently deleterious effects of AtP5CS1 on grain quality,tiller number,and grain yield in the field indicated the unsuitability of P5CS for drought-tolerance breeding. | Xuanjun Feng Yue Hu Weixiao Zhang Rongqian Xie Huarui Guan Hao Xiong Li Jia Xuemei Zhang Hanmei Zhou Dan Zheng Ying Wen Qingjun Wang Fengkai Wu Jie Xu Yanli Lu | 2022 | The Crop Journal2022，10，4： | 2 |
| 7 | Systematic screening of common wastewater-marking pharmaceuticals in urban aquatic environments: implications for environmental risk control显示文摘 | Haidong Zhou Qingjun Zhang Xuelian Wang Qianqian Zhang Lixin Ma Yong Zhan | 2014 | Environmental Science and Pollution Research2014，，11： | 1 |
| 8 | Rusting behavior and preventative measures of hot-rolled steel plates for automobile applications显示文摘As one of the important categories of hot-rolled products,hot-rolled steel plates for automobile applications generally undergo uniform corrosion or localized corrosion according to different environments of manufacturing,transportation and/or storage of the plates.General corrosion often takes place on the surface of a plate in the exterior part of a package,and only reduces the thickness of the plate and slightly increases the roughness of the surface; however,localized corrosion on the surface of a plate inside the package is likely to result in the formation of pit-like defects on the substrate of the plate,which cannot be removed thoroughly by normal acid pickling or sand blasting,and affects the application of the plate.This research report analyzes the phenomena and characteristics of the rusting behavior of hot-rolled steel plates for automobile applications,and the influencing factors are summaried.The corresponding preventative measures are proposed. | QI Huibin QIAN Yuhai ZHANG Hua ZHOU Qingjun WANG Wei | 2009 | Baosteel Technical Research2009，3，2： | 1 |
| 9 | Template-free hydrothermalsynthesis of ZnO micro/nano-materials and their application inacetone sensing properties 显示文摘 | Dongmin An Xiaoqiang Tong Jincheng Liu Qiong Wang Qingjun Zhou Juan Dong Yan Li | 2015 | Superlattices and Microstructures2015，77，： | 1 |
| 10 | Washing out heavy metals from contaminated soils from an iron and steel smelting site显示文摘洗是为由化学动员分开土壤 ex-situ 的粒子一定的沾染物的一个有希望的方法。实验室批洗实验用 deionized 水和草酸酸的变化集中被进行,柠檬性的酸的、酒石的酸,醋酸,盐酸酸和 ethylenediaminetetra 醋酸( EDTA )弄脏估计把这些化学药品用作洗代理人的效率并且重重地从二清理重金属从一个熨斗和 streel 熔炼地点的土壤。毒性减小索引和补习费用被分析,并且结果证明土壤与 Cd, Pb 和 Zn 被弄脏。盐酸酸和 EDTA 是比在测试土壤的补习的另外的洗的代理人更有效的。最大的全部的毒性减小索引显示出毛孔散开不是在吸附过程的限制率的步的那 0.5 molggests。覰?覰?? | Guangxu ZHU Qingjun GUO Junxing YANG Hanzhi ZHANG Rongfei WEI Chunyu WANG Marc PETERS Xiaoyong ZHOU Jun YANG | 2015 | Frontiers of Environmental Science & Engineering2015，9，4： | 1 |
| 11 | Effect of the extract of intestine from stressed rat on lymphocyte proliferation in vitro显示文摘Immuno-suppressive protein, with a molecular weight of 155 and 370 ku, was generated in spleen and lymph node in stressed rats. It strongly inhibited lymphocyte proliferation. The results of activity assay, molecular weight determination and histological localization all demonstrated that under stress the immuno-suppressive protein was also generated in intestinal mucosa of rats. | Qingjun Huang Xiansuo Zhou Shaoguang Fan | 1998 | Chinese Science Bulletin1998，43，17： | 1 |
| 12 | Overexpression of Bmi-1 contributes to the invasion and metastasis ofhepatocellular carcinoma by increasing the expression of matrix metalloproteinase(MMP)?2, MMP-9 and vascular endothelial growth factor via the PTEN/PI3K/Akt pathway显示文摘 | Xiaolei Li Zhaoxu Yang Wenjie Song Liang Zhou Qingjun Li Kaishan Tao Jingshi Zhou Xing Wang Zhigang Zheng Nan You Kefeng Dou Haimin Li | 2013 | International Journal of Oncology2013，，3： | 1 |
| 13 | Kinetic study of polysulfide-acrylate click reaction by DEA and DMA显示文摘 | Zhou Baijie Shen Mingxia Wang Qingjun | | 0，，12： | 1 |
| 14 | Experiment study on fatigue beahivor of steeel reinforced concrete girders at high-speed railway station显示文摘 | TONG Lewei XIAN Qingjun ZHOU Liying | 2013 | Journal of tongji university (natural science)2013，41，3： | 1 |
| 15 | Acute and subchronic toxicity of hydroxylammonium nitrate in Wistar rats显示文摘Hydroxylammonium nitrate(HAN) is a major constituent in a class of liquid monopropellants and is extensively used in nuclear industry and space propulsion.Previous toxicological studies have focused on oral,inhalation and dermal routes of exposure to HAN-based propellant blends.In this study,acute and subchronic toxicity of HAN in Wistar rats by intraperitoneal injections were evaluated.In this acute study,doses of HAN at 115,125,135,147,160 or 174 mg/kg were administered.No adverse effects were observed during a 14-day period and at gross histopathological examination.In the subchronic study,HAN at 7,14 or 28 mg/kg were administered for 13 weeks.The treatment with HAN caused significant changes in the weight of spleen,in the level of hematological parameters,total bilirubin,direct bilirubin,uric acid and carbondioxidecombining power and histopathological damages of the lung,liver,spleen and kidney.Overall,the study suggests that 13-week HAN treatment caused abnormal hematological changes and tissue lesions,and the risk of toxicity to mammals is not negligible. | An Hui Liu Jinyi Yang Lujun Liu Shengxue Zhou Yanhong Yang Huan Jia Qingjun Cui Zhihong Cao Jia | 2008 | Journal of Medical Colleges of PLA(China)2008，23，3： | 1 |
| 16 | SmBaCo2O5+δ double-perovs- kite structure cathode material for intermediate-temperature solid-oxide fuel cells 显示文摘 | ZHOU Qingjun HE Tianmin JI Yuan | 2008 | J Power Sources2008，185，： | 1 |
| 17 | The role of corneal endothelium in macular corneal dystrophy development and recurrence显示文摘Macular corneal dystrophy(MCD)is a progressive,bilateral stromal dystrophic disease that arises from mutations in carbohydrate sulfotransferase 6(CHST6).Corneal transplantation is the ultimate therapeutic solution for MCD patients.Unfortunately,postoperative recurrence remains a significant challenge.We conducted a retrospective review of a clinical cohort comprising 102 MCD patients with 124 eyes that underwent either penetrating keratoplasty(PKP)or deep anterior lamellar keratoplasty(DALK).Our results revealed that the recurrence rate was nearly three times higher in the DALK group(39.13%,9/23 eyes)compared with the PKP group(10.89%,11/101 eyes),suggesting that surgical replacement of the corneal endothelium for treating MCD is advisable to prevent postoperative recurrence.Our experimental data confirmed the robust m RNA and protein expression of CHST6 in human corneal endothelium and the rodent homolog CHST5 in mouse endothelium.Selective knockdown of wild-type Chst5 in mouse corneal endothelium(AC^(siChst5)),but not in the corneal stroma,induced experimental MCD with similar extracellular matrix synthesis impairments and corneal thinning as observed in MCD patients.Mice carrying Chst5 point mutation also recapitulated clinical phenotypes of MCD,along with corneal endothelial abnormalities.Intracameral injection of wild-type Chst5 rescued the corneal impairments in AC^(siChst5)mice and retarded the disease progression in Chst5 mutant mice.Overall,our study provides new mechanistic insights and therapeutic approaches for MCD treatment by highlighting the role of corneal endothelium in MCD development. | Bi-Ning Zhang Benxiang Qi Chunxiao Dong Bin Zhang Jun Cheng Xin Wang Suxia Li Xiaoyun Zhuang Shijiu Chen Haoyun Duan Dewei Li Sujie Zhu Guoyun Li Yihai Cao Qingjun Zhou Lixin Xie | 2024 | Science China(Life Sciences)2024，67，2： | 0 |
| 18 | Corrosion performance and applicability evaluation of nickel-based alloys for oil and gas production tubing applications显示文摘The sulfide stress corrosion cracking( SSC) performance of G3 and 028 nickel-based alloys w as studied using slow strain rate test( SSRT) and the four-point bend( FPB) test under simulated dow nhole conditions. The effect of high temperature,high H2 S / CO2 partial pressure,and the presence of sulfur on SSC susceptibility w as investigated. The G3 alloy w as found to have a higher SSC resistance than the 028 alloy. Presence of sulfur and temperature bear a strong influence on the SSC performance of the metals,particularly on the 028 alloy. The applicability of 028 and G3 alloys may be expanded and both could safely be used beyond the limits set by the ISO15156-3 standard. | ZHOU Qingjun ZHANG Zhonghua YANG Jianqiang | 2015 | Baosteel Technical Research2015，9，4： | 0 |
| 19 | Corrosion characteristics and mechanism of the S135 drill pipes in slurry显示文摘The corrosion mechanism of the S135 drill pipes was investigated through observation of the corrosion morphology and analysis of the corrosion products by scanning electronic microscope (SEM),energy dispersive spectrum (EDS) and X-ray diffraction (XRD).The results show that the localized corrosion on the outer surface of the drill pipes was caused by oxygen corrosion due to the action of retained slurry.Cl- contained in slurry accelerated the corrosion and promoted the development of corrosion pits.Suggestions for mitigating or preventing such corrosion of the drill pipes are proposed based on the research results. | ZHOU Qingjun GUO Jinbao QI Huibin QIAN Yuhai WANG Wei | 2009 | Baosteel Technical Research2009，3，2： | 0 |
| 20 | Effect of Cl- on electrochemical corrosion behavior of H2S显示文摘In the process of natural gas transportation in high-sulfur oil and gas fields,the inner wall of the pipeline absorbs large quantities of condensate water due to the different temperatures inside and outside the pipeline.This condensate water dissolves a number of other ions.On one hand,these ions lead to the dissolution of H2S and reduce the concentration of the acid corrosion reduction due to the ions having the same effect as salt.On the other hand,the ions in the electrochemical corrosion process can promote charge transfer and accelerate electrochemical reactions.Polarization curves and AC impedance measurements were used to investigate the effects of different Cl^- and S^2- concentrations on the electrochemical behavior of H2S. | LIU Mingliang ZHOU Qingjun QI Qingju | 2019 | Baosteel Technical Research2019，13，3： | 0 |
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