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| 1 | Additive manufacturing of high-strength CrMnFeCoNi high-entropy alloys-based composites with WC addition显示文摘Laser melting deposition with WC addition has been developed to fabricate high-strength CrMnFeCoNibased high-entropy alloys-based composites.By this technique,a microstructure of compact refined equiaxed grains can be achieved,and the tensile strength can be remarkably improved.The sample with 5 wt%WC addition shows a promising mechanical performance with a tensile strength of 800 MPa and an elongation of 37%.The improvement in mechanical property may be attributed to the formation of Cr(23)C6 reinforcement precipitates,which could promote the heterogeneous nucleation of grains and hinder the propagation of slip bands. | Jinfeng Li Shuo Xiang Hengwei Luan Abdukadir Amar Xue Liu Siyuan Lu Yangyang Zeng Guomin Le Xiaoying Wang Fengsheng Qu Chunli Jiang Guannan Yang | 2019 | Journal of Materials Science & Technology2019，35，11： | 13 |
| 2 | Tuning the dual-active sites of ZIF-67 derived porous nanomaterials for boosting oxygen catalysis and rechargeable Zn-air batteries显示文摘The rational control of the active site of metal-organic frameworks(MOFs)derived nanomaterials is essential to build efficient bifunctional oxygen reduction/evolution reaction(ORR/OER)catalysts.Accordingly,through designing and constructing a Co_(3)O_(4)-Co heterostructure embedded in Co,N co-doped carbon polyhedra derived(Co_(3)O_(4)-Co@NC)from the in-situ compositions of ZIF-67 and cobalt nanocrystals synthesized by the strategy of in-situ NaBH4 reduction,the dual-active site(Co_(3)O_(4)-Co and Co-N_(x))is synchronously realized in a MOFs derived nanomaterials.The formed Co_(3)O_(4)-Co@NC shows excellent bifunctional electrocatalytic activity with ultra-small potential gap(ΔE=E_(j=10)(OER)–E_(1/2)(ORR))of 0.72 V,which surpasses the commercial Pt/C and RuO_(2) catalysts.The theory calculation results reveal that the excellent bifunctional electrocatalytic activity can be attributed to the charge redistribution of Co of Co-N_(x) induced by the synergistic effects of well-tuned active sites of Co_(3)O_(4)-Co nanoparticle and Co-N_(x),thus optimizing the rate-determining step of the desorption of O_(2)^(*)intermediate in ORR and OH^(*)intermediate in OER.The rechargeable Zn-air batteries with our bifunctional catalysts exhibit superior performance as well as high cycling stability.This simple-effective optimization strategy offers prospects for tuning the active site of MOF derived bifunctional catalyst in electrochemical energy devices. | Zeyi Zhang Yangyang Tan Tang Zeng Liyue Yu Runzhe Chen Niancai Cheng Shichun Mu Xueliang Sun | 2021 | Nano Research2021，14，7： | 3 |
| 3 | Microstructure and electrical properties of (Pb 0.87 Ba 0.1 La 0.02 )(Zr 0.68 Sn 0.24 Ti 0.08 )O 3 anti-ferroelectric ceramics fabricated by the hot-press sintering method显示文摘 | Guangzu Zhang Sisi Liu Yan Yu Yike Zeng Yangyang Zhang Xu Hu Shenglin Jiang | 2013 | Journal of the European Ceramic Society2013，，1： | 1 |
| 4 | Repercussions of COVID-19 pandemic on solid waste generation and management strategies显示文摘It has been over ten months since the beginning of the 2019 coronavirus disease(COVID-2019),and its impact on solid waste management,especially medical waste,is becoming clearer.This study systematically reviews the potential influences of the COVID-19 pandemic on medical waste,personal protection equipment waste and municipal solid waste(MSW),and discusses the corresponding measures and policies of solid waste management in typical countries.The results show that the generation of medical waste from the pandemic increased significantly,with 18%‒425%growth.It is estimated that the daily output of COVID-19 medical waste increased from 200 t/d on Feb.22 to over 29000 t/d at the end of September 2020 throughout the world.The use of personal protective equipment will continue to grow in the long-term,while the blockade and isolation measures greatly reduced the volume of commercial waste,especially for tourist cities,and part of this waste was transferred to household waste.Residents’attitudes and behavior toward food waste have changed due to the COVID-19 pandemic.In response to the pandemic,international organizations and several countries have issued new policies and guidelines and adjusted their management strategies for medical waste and MSW treatment.The pandemic has brought specific challenges to the disposal capacity of medical waste worldwide.It has also brought about the stagnation of policies related to the reduction of plastic products and waste recycling.This study will provide some useful information for managers and governmental officials on effective solid waste management during and after the COVID-19 pandemic. | Yangyang Liang Qingbin Song Naiqi Wu Jinhui Li Yuan Zhong Wenlei Zeng | 2021 | Frontiers of Environmental Science & Engineering2021，15，6： | 1 |
| 5 | Optimizing Winding Angles of Reinforced Thermoplastic Pipes Based on Progressive Failure Criterion显示文摘This paper examines a scheme to optimize the multiple winding angles of reinforced thermoplastic pipes(RTPs)under internal and external pressures.To consider the nonlinear mechanical behavior of the material under changes of winding angle due to deformation,we use three-dimensional(3D)thick-walled cylinder theory with the 3D Hashin failure criterion and theory of the evolution of damage to composite materials,to formulate a model that analyzes the progressive failure of RTPs.The accuracy of the model was verified by experiments.A model to optimize the multiple winding angles of the RTPs was then established using the model for progressive failure analysis and a multi-island genetic algorithm.The optimal scheme for winding angles of RTPs capable of withstanding the maximum internal/external pressure was obtained.The simulation results showed that the ply number of the reinforced layer has a prominent nonlinear effect on the internal and external pressure capacity of the RTPs.Compared with RTPs with a single angle of±55°,the multiple winding angle overlay scheme based on the multi-angle optimization model improved the internal and external pressure capacity of the RTPs,and the improvement in the external pressure capacity was significantly better than the internal pressure carrying capacity. | WANG Yangyang LOU Min ZENG Xin DONG Wenyi WANG Sen | 2021 | Journal of Ocean University of China2021，20，5： | 1 |
| 6 | Oligomannuronate-Chromium (Ⅲ) Complex Ameliorates Insulin Resistance in C57BL/KsJ-db/db Mice显示文摘Diabetes mellitus is the most common metabolic disease and its prevalence is increasing in many countries year by year.More than 90% of diabetes patients are type 2 diabetes,which is caused by insulin resistance and beta-cell dysfunction.In this paper,the oligomannuronate-chromium(III)complex(OM2)was prepared and its effect and mechanism on attenuating insulin resistance in diabetic C57BL/KsJ-db/db mice were studied.The results indicated that oral intake of OM2(50 mg kg-1d-1)for 42 d decreased blood glucose and lipid concentration,which was associated with the reduced serum insulin concentration and insulin resistance.According to western blot assay,OM2 could activate AMPK pathway to regulate glycogen synthesis,gluconeogenesis and lipid metabolism in the liver,and attenuate the hyperglycemic symptom in db/db mice.The effects of OM2 on attenuating insulin resistance were com-parable to that of the established antidiabetic drug metformin,and OM2 showed less adverse effect than metformin in vivo.Based on the effectiveness and low toxicity,OM2 may potentially be used for prevention and treatment of type 2 diabetes mellitus. | HAO Cui HAO Jiejie WANG Wei LI Guangsheng ZENG Yangyang WANG Peipei ZHAO Xia YU Guangli | 2011 | Journal of Ocean University of China2011，10，4： | 1 |
| 7 | Polysaccharides Purified from Wild Cordyceps Activate FGF2/FGFR1c Signaling显示文摘Land animals as well as all organisms in ocean synthesize sulfated polysaccharides. Fungi split from animals about 1.5 billion years ago. As fungi make the evolutionary journey from ocean to land, the biggest changes in their living environment may be a sharp decrease in salt concentration. It is established that sulfated polysaccharides interact with hundreds of signaling molecules and facilitate many signaling transduction pathways, including fibroblast growth factor(FGF) and FGF receptor signaling pathway. The disappearance of sulfated polysaccharides in fungi and plants on land might indicate that polysaccharides without sulfation might be sufficient in facilitating protein ligand/receptor interactions in low salinity land. Recently, it was reported that plants on land start to synthesize sulfated polysaccharides in high salt environment, suggesting that fungi might be able to do the same when exposed in such environment. Interestingly, Cordyceps, a fungus habituating inside caterpillar body, is the most valued traditional Chinese Medicine. One of the important pharmaceutical active ingredients in Cordyceps is polysaccharides. Therefore, we hypothesize that the salty environment inside caterpillar body might allow the fungi to synthesize sulfated polysaccharides. To test the hypothesis, we isolated polysaccharides from both lava and sporophore of wild Cordyceps and also from Cordyceps militaris cultured without or with added salts. We then measured the polysaccharide activity using a FGF2/FGFR1 c signaling-dependent Ba F3 cell proliferation assay and found that polysaccharides isolated from wild Cordyceps activated FGF2/FGFR signaling, indicating that the polysaccharides synthesized by wild Cordyceps are indeed different from those by the cultured mycelium. | ZENG Yangyang HAN Zhangrun YU Guangli HAO Jiejie ZHANG Lijuan | 2015 | Journal of Ocean University of China2015，14，1： | 1 |
| 8 | Correlation between Vascular Calcification and Serum Sclerostin in MHD Patients显示文摘Objective Investigate the correlation between serum sclerostinlevel and chronic kidney disease-mineral and bone disorder(CKD-MBD),especially vascular calcification,in maintenance hemodialysis(MHD)patients.Methods This is across-sectional study,a total of 72 MHD patients were included from the first affiliated hospital of Jinan university.Measure the biochemical indicators of mineral metabolism,renal function,and serum sclerostin level by ELISA.The abdominal aorta calcification score(AACS)was assessed according to Kauppila method on lateral spine imaging using DEXA.Patients were distributed into two groups according to the level of serum sclerostin:low sclerostingroup(≤125 pg/ml)and high sclerostingroup(>125 pg/ml).Analyze the association of serum sclerostin level with the indicators of CKD-MBD.Results There was significant difference in i PTH level between high sclerost in group and low sclerost in group.Multivariate Logistic regression analysis demonstrated that dialysis duration,male and anuria were independent risk factor of high sclerostin level,and i PTH and Kt/V were protective factors.Conclusion Dialysis duration,man,anuria was independent risk factors and i PTH,Kt/V were protective factors of high serum sclerostin level in MHD patients.There was no correlation between abdominal aorta calcification and serum sclerostin level. | Yangyang Zhang Shufei Zeng Chen Yun Lifeng Yang Fanna Liu Guanmin Wu Taksui Wong Bo Hu Xiangnan Dong Folan Li Yu Chen Peitian Yang Aiyun Cha Huanhuan Liu Mingming Ma B.Hocher W. Pommer Huiyuan Zheng Tong Liu Zuhui Chen Lianghong Yin | 2017 | 临床医学工程2017，24，S1： | 0 |
| 9 | Advances in Diagnosis and Treatment of Neuropsychiatric Systemic Lupus Erythematosus显示文摘1 Introduction Neuropsychiatric systemic lupus erythematosus(NPSLE)is a serious complication of systemic lupus erythematosus(SLE),with an incidence of about 30%to 40%[1].No matter early or late SLE patients are prone to concurrent,so early diagnosis and treatment of NPSLE is extremely important. | Shufei Zeng Yangyang Zang Dezhen Chen Baozhang Guan Fanna Liu Mingming Ma Yu Mong Huiyuan Zheng Aiyun Cha Xiangnan Dong Huanhuan Liu Taksui Wong Shuang Cui Tong Liu Yongpin Lu Chen Yun Hongwei Hu B.Hocher W.Pommer Zuhui Chen Lianghong Yin | 2017 | 临床医学工程2017，24，S1： | 0 |
| 10 | Cytoplasmic YAP1-mediated ESCRT-III assembly promotes autophagic cell death and is ubiquitinated by NEDD4L in breast cancer显示文摘Background:Nuclear Yes1-associated transcriptional regulator(YAP1)promotes tumor progression.However,the function of cytoplasmic YAP1 in breast cancer cells and its impact on the survival of breast cancer patients remain unclear.Our research aimed to explore the biological function of cytoplasmic YAP1 in breast cancer cells and the possibility of cytoplasmic YAP1 as a predictive marker of breast cancer survival.Methods:We constructed cell mutant models,including NLS-YAP15SA(nuclear localized),YAP1S94A(incapable of binding to the TEA domain transcription factor family)and YAP1S127D(cytoplasmic localized),and used Cell Counting Kit-8(CCK-8)assays,5-ethynyl-2’-deoxyuridine(EdU)incorporation assays,and Western blotting(WB)analysis to detect cell proliferation and apoptosis.The specific mechanism of cytoplasmic YAP1-mediated endosomal sorting complexes required for transport III(ESCRT-III)assembly was studied by co-immunoprecipitation,immunofluorescence staining,and WB analysis.Epigallocatechin gallate(EGCG)was used to simulate YAP1 retention in the cytoplasm in in vitro and in vivo experiments to study the function of cytoplasmic YAP1.YAP1 binding to NEDD4-like E3 ubiquitin protein ligase(NEDD4L)was identified using mass spectrometry and was verified in vitro.Breast tissue microarrays were used to analyze the relationship between cytoplasmic YAP1 expression and the survival of breast cancer patients.Results:YAP1 was mainly expressed in the cytoplasm in breast cancer cells.Cytoplasmic YAP1 promoted autophagic death of breast cancer cells.Cytoplasmic YAP1 bound to the ESCRT-III complex subunits charged multivesicular body protein 2B(CHMP2B)and vacuolar protein sorting 4 homolog B(VPS4B),promoting assembly of CHMP2B-VPS4B and activating autophagosome formation.EGCG retained YAP1 in the cytoplasm,promoting the assembly of CHMP2B-VPS4B to promote autophagic death of breast cancer cells.YAP1 bound to NEDD4L,and NEDD4L mediated ubiquitination and degradation of YAP1.Breast tissue microarrays revealed that high levels of cytoplasmic YAP1 were beneficial to the survival of breast cancer patients.Conclusions:Cytoplasmic YAP1 mediated autophagic death of breast cancer cells by promoting assembly of the ESCRT-III complex;furthermore,we established a new breast cancer survival prediction model based on cytoplasmic YAP1 expression. | Yan Guo Yuqing Cui Yangyang Li Xiaoying Jin Dandan Wang Mengxia Lei Fengzhi Chen Yali Liu Jinwen Xu Guanyu Yao Guangchun Zeng Xuesong Chen | 2023 | Cancer Communications2023，43，5： | 0 |
| 11 | Guided Dropout: Improving Deep Networks Without Increased Computation显示文摘Deep convolution neural networks are going deeper and deeper.How-ever,the complexity of models is prone to overfitting in training.Dropout,one of the crucial tricks,prevents units from co-adapting too much by randomly drop-ping neurons during training.It effectively improves the performance of deep net-works but ignores the importance of the differences between neurons.To optimize this issue,this paper presents a new dropout method called guided dropout,which selects the neurons to switch off according to the differences between the convo-lution kernel and preserves the informative neurons.It uses an unsupervised clus-tering algorithm to cluster similar neurons in each hidden layer,and dropout uses a certain probability within each cluster.Thereby this would preserve the hidden layer neurons with different roles while maintaining the model’s scarcity and gen-eralization,which effectively improves the role of the hidden layer neurons in learning the features.We evaluated our approach compared with two standard dropout networks on three well-established public object detection datasets.Experimental results on multiple datasets show that the method proposed in this paper has been improved on false positives,precision-recall curve and average precision without increasing the amount of computation.It can be seen that the increased performance of guided dropout is thanks to shallow learning in the net-works.The concept of guided dropout would be beneficial to the other vision tasks. | Yifeng Liu Yangyang Li Zhongxiong Xu Xiaohan Liu Haiyong Xie Huacheng Zeng | 2023 | Intelligent Automation & Soft Computing2023，，6： | 0 |
| 12 | MoTransFrame:Model Transfer Framework for CNNs on Low-Resource Edge Computing Node显示文摘Deep learning technology has been widely used in computer vision,speech recognition,natural language processing,and other related fields.The deep learning algorithm has high precision and high reliability.However,the lack of resources in the edge terminal equipment makes it difficult to run deep learning algorithms that require more memory and computing power.In this paper,we propose MoTransFrame,a general model processing framework for deep learning models.Instead of designing a model compression algorithm with a high compression ratio,MoTransFrame can transplant popular convolutional neural networks models to resources-starved edge devices promptly and accurately.By the integration method,Deep learning models can be converted into portable projects for Arduino,a typical edge device with limited resources.Our experiments show that MoTransFrame has good adaptability in edge devices with limited memories.It is more flexible than other model transplantation methods.It can keep a small loss of model accuracy when the number of parameters is compressed by tens of times.At the same time,the computational resources needed in the reasoning process are less than what the edge node could handle. | Panyu Liu Huilin Ren Xiaojun Shi Yangyang Li Zhiping Cai Fang Liu Huacheng Zeng | 2020 | Computers, Materials & Continua2020，，12： | 0 |
| 13 | Tribological properties of low-temperature time-dependent pretreated graphite for mechanical seal pairs in high-speed turbopump显示文摘The friction coefficient and wear rate of pretreated graphite with liquid nitrogen were obtained by using a ball-on-disk tester,and the wear of GCr15–graphite seal pairs with the low-temperature time-dependent pretreatment was discussed by comparing the wear morphology.The results show that liquid nitrogen pretreatment can affect the hardness and interlayer spacing of graphite.The range of the friction coefficients of pretreated graphite changes from 0.17 to 0.22.With the increase of liquid nitrogen pretreatment time,the wear mechanism of graphite would change from dominated three-body wear to adhesion wear.The experimental results of the mechanical seal with liquid nitrogen pretreatment show that the wear rate of stator is less than 0.00165 mm^(3)·N^(−1)·m^(−1),and the graphite shows a good low-temperature compatibility. | Yangyang ZHAO Guoyuan ZHANG Junqian WANG He WANG Weigang ZHAO Qunfeng ZENG | 2024 | Friction2024，12，2： | 0 |
| 14 | Exploration of Graduate Student Cultivation Mode of Landscape Architecture under the Background of“Artificial Intelligence+X”显示文摘Under the background of“artificial intelligence+X”,the development of landscape architecture industry ushers in new opportunities,and professional talents need to be updated to meet the social demand.This paper analyzes the cultivation demand of landscape architecture graduate students in the context of the new era,and identifies the problems by comparing the original professional graduate training mode.The new cultivation mode of graduate students in landscape architecture is proposed,including updating the target orientation of the discipline,optimizing the teaching system,building a“dualteacher”tutor team,and improving the“industry-university-research-utilization”integrated cultivation,so as to cultivate high-quality compound talents with disciplinary characteristics. | CAO Yangyang ZENG Junfeng | 2024 | Journal of Landscape Research2024，16，1： | 0 |
| 15 | Cold Start Problem of Vehicle Model Recognition under Cross-Scenario Based on Transfer Learning显示文摘As a major function of smart transportation in smart cities,vehicle model recognition plays an important role in intelligent transportation.Due to the difference among different vehicle models recognition datasets,the accuracy of network model training in one scene will be greatly reduced in another one.However,if you don’t have a lot of vehicle model datasets for the current scene,you cannot properly train a model.To address this problem,we study the problem of cold start of vehicle model recognition under cross-scenario.Under the condition of small amount of datasets,combined with the method of transfer learning,load the DAN(Deep Adaptation Networks)and JAN(Joint Adaptation Networks)domain adaptation modules into the convolutional neural network AlexNet and ResNet,and get four models:AlexNet-JAN,AlexNet-DAN,ResNet-JAN,and ResNet-DAN which can achieve a higher accuracy at the beginning.Through experiments,transfer the vehicle model recognition from the network image dataset(source domain)to the surveillance-nature dataset(target domain),both Top-1 and Top-5 accuracy have been improved by at least 20%. | Hongbo Wang Qian Xue Tong Cui Yangyang Li Huacheng Zeng | 2020 | Computers, Materials & Continua2020，，4： | 0 |
| 16 | Dual inhibition of CDK4 and FYN leads to selective cell death in KRAS-mutant colorectal cancer显示文摘Dear Editor,Activating mutations in KRAS have been found in nearly 50%of colorectal cancers(CRCs),and patients with KRAS mutations are resistant to the anti-EGFR agent cetuximab1.Currently,though there are several strategies targeting the mutated cysteine in KRAS(G12C;http://gffzzd3f38a9638994581h9non9x5wvxku6op5.ffgz.tsg.suse.edu.cn/ct2/show/NCT03600883),the frequency of the KRAS G12C mutation is much lower in CRC than in lung adenocarcinoma2.Thus,it is urgent to increase efforts to develop a novel strategy for KRAS-mutant CRC. | Yan Wang Rongjie Lin Huan Ling Yuan Ke Yangyang Zeng Yudi Xiong Qian Zhou Fuxiang Zhou Yunfeng Zhou | 2019 | Signal Transduction and Targeted Therapy2019，4，1： | 0 |
| 17 | Constructing origami power generator from one piece of electret thin film and application in AIenabled transmission line vibration monitoring显示文摘One of the crucial issues for applying electret/triboelectric power generators in the Internet of Things(IoT)is to take full advantage of specific high voltage signals and enable self-powered sensing.Therefore,inspired by Miura-origami,we present an innovative origami power generator(OPG)constructed from only one piece of electret thin film.The Miura-origami architecture realizes a generator with excellent deformability and stretchability and makes it unnecessary for any auxiliary support structure during the compress-release cycle.Various parameters of the generator are intensively investigated,including the excitation accelerations,excitation displacements,numbers of power generation units and deformation degree of the device.When stimulated with 5.0 g acceleration at 15 Hz frequency,the generator with 8 generation units can obtain an instantaneous peak-to-peak voltage and a remarkable optimum peak power of 328 V and 2152μW at 50MΩ,respectively.In addition,the regulable shape and multiple generation modes of the device greatly improve its applicability in various vibration energy collection requirements.Based on the above results,a hexagonal electret generator integrated with six-phase OPGs is developed as a“Buoy on Sky,”after which the signal waveforms generated from internal power generators are recognized with 92%accuracy through a neural network algorithm that identifies the vibration conditions of transmission lines.This work demonstrates that a fusion of origami art and energy conversion techniques can achieve a multifunctional generator design satisfying the requirements for IoT applications. | Boming Lyu Huipeng Zhou Yangyang Gao Xinhui Mao Fangzhi Li Jiyuan Zhang Dezhi Nie Wen Zeng Yonglin Lu Jin Wu Zhaoshu Yang Kai Tao | 2023 | Microsystems & Nanoengineering2023，9，4： | 0 |
| 18 | CAR-T cells for cancer immunotherapy显示文摘Adoptive immunotherapy expressing synthetic chimeric antigen receptors(CAR)on T cells through in vitro modifications represents a new and innovative strategy in cancer treatment.This new approach enables T cells to recognize and bind tumor antigens via a single-chain variable fragment recognition domain,circumventing the restriction of major histocompatibility complex.This review summarized the structure/design of CAR-T cells and the evolution process this technology went through,displaying the theoretical foundation for CAR-T therapy,the marketed products and the latest preclinical and clinical research progress.Finally,we provided perspectives on this technology’s development and potential future applications,especially for treating hematological malignant and solid tumors. | Yangyang Xie Xiaotong Li Jingyi Wu Huiling Zeng Hamza Boucetta Binru Wang Pei Yang Wei He | 2023 | Chinese Chemical Letters2023，34，9： | 0 |
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